The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

Journal of Experimental Medicine

Volumn 187, Issue 9, 1998, Pages 1417-1426

  Frearson, Julie A ^a   Alexander, Denis R ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ARTICLE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANNEXIN A2; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GRB2 ADAPTOR PROTEIN; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MUROMONAB-CD3; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION;

EID: 0032482171     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.9.1417     Document Type: Article

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