Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C- 1027 apoprotein

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 2, 2000, Pages 382-392

  Liu, Wen ^a,b   Shen, Ben ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC C 1027; ANTINEOPLASTIC ANTIBIOTIC; BACTERIAL DNA; CARRIER PROTEIN; HYDROLYASE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA DETERMINATION; DRUG STRUCTURE; GENE CLUSTER; GENE LOCATION; GENE MUTATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESTRICTION MAPPING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STREPTOMYCES; STREPTOMYCES GLOBISPORUS;

AMINO ACID SEQUENCE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, BACTERIAL; DNA, BACTERIAL; ENEDIYNES; FUNGAL PROTEINS; GENETIC COMPLEMENTATION TEST; HYDRO-LYASES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES;

EID: 0033984077     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.2.382-392.2000     Document Type: Article

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