Moderate wine and alcohol consumption: Beneficial effects on cardiovascular disease

Thrombosis and Haemostasis

Volumn 86, Issue 2, 2001, Pages 517-528

  Booyse, F M ^a   Parks, D A ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Alcohol; CHD; Endothelial cells; Platelets; Polyphenols

Indexed keywords

ALCOHOL; ANTICOAGULANT AGENT; BETA2 GLYCOPROTEIN 1; CATECHIN; EPICATECHIN; ESTROGEN; FLAVONOID; HEAT SHOCK PROTEIN 70; LIPOPROTEIN; NITRIC OXIDE; ORAL CONTRACEPTIVE AGENT; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; TISSUE FACTOR PATHWAY INHIBITOR;

ALCOHOL CONSUMPTION; ARTERY THROMBOSIS; BLOOD CLOTTING; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAUSE OF DEATH; CLINICAL TRIAL; DISEASE COURSE; ENDOTHELIUM CELL; ENVIRONMENTAL FACTOR; EXPERIMENTAL MODEL; FIBRINOLYSIS; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART PROTECTION; HEMOSTASIS; HUMAN; ISCHEMIC HEART DISEASE; MONOCYTE; MORTALITY; NONHUMAN; PATHOGENESIS; POSTMENOPAUSE; PRIORITY JOURNAL; REVIEW; SMOOTH MUSCLE FIBER; SYSTEMIC CIRCULATION; THROMBOCYTE; VASCULAR LESION; WINE;

EID: 0034897516     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616080     Document Type: Review

References (176)

1. Alcohol and risk of coronary events
2. Light-to-moderate alcohol consumption and mortality in the Physicians' Health Study enrollment cohort
3. Drinking habits and cardiovascular disease: The Framingham Study
4. Alcohol consumption and risk of coronary heart disease
5. Alcohol drinking and mortality among men enrolled in an American Cancer Society prospective study
6. A prospective study of moderate alcohol consumption and the risk of coronary heart disease and stroke in women
7. Ten-year incidence of coronary heart disease in the Honolulu Heart Program
8. Frequency of alcohol consumption and morbidity and mortality: The Yugoslavia cardiovascular disease study
9. Intake of spirits and beer and risk of myocardial infarction and death: A longitudinal study in eastern Finland
10. Mortality associated with moderate intakes of wine, beer, or spirits
11. Risks of cardiovascular mortality in alcohol drinkers, ex-drinkers and nondrinkers
12. Wine, alcohol, platelets, and the French paradox for coronary heart disease
13. Alcohol and the cardiovascular system
14. Beneficial effect of moderate alcohol consumption on vascular disease: Myth or reality?
15. High density lipoprotein: The clinical implication of recent studies
16. The effect of cessation and resumption of moderate alcohol intake on serum high-density-lipoprotein subfractions. A controlled study
17. Rapid decrease in high density lipoprotein subfractions and post heparin plasma lipase activity after cessation of chronic alcohol intake
18. Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction
19. Effect of alcohol intake on high and low density lipoprotein metabolism in healthy volunteers
20. Serum high-density lipoprotein particles of alcohol-fed rats are deficient in apolipoprotein E
21. Comparison of the effects of two different doses of alcohol on serum lipoproteins, HDL-subfractions and apolipoproteins A-I and A-II: A controlled study
22. Moderate alcohol feeding attenuates postinjury vascular cell proliferation in rabbit angioplasty model
23. Lipoproteins and blood pressure as biological pathways for effect of moderate alcohol consumption on coronary heart disease
24. The effect of moderate alcohol intake on serum apolipoprotein A-1-containing lipoproteins and lipoprotein (a)
25. The effect of ethanol on hemostatic properties of human blood platelets
26. Alcohol and platelet aggregation: The Caerphilly Prospective Heart Disease Study
27. Alcohol and platelet function
28. Effect of ethanol on platelet function
29. Inhibitory effect of alcohol on platelet functions of rats fed saturated fats
30. Platelet aggregation and plasma lipoproteins in alcoholics during alcohol withdrawal
31. What supports the role of alcohol as a risk factor for stroke?
32. Effects of acute, moderate ethanol consumption on human platelet aggregation in platelet-rich plasma and whole blood
33. Acute administration of ethanol to rabbits inhibits thrombus formation induced by indwelling aortic catheters
34. Administration of wine and grape juice inhibits in vivo platelet activity and thrombosis in stenosed canine coronary arteries
35. Ethanol inhibits thrombin-induced secretion by human platelets at a site distinct from phospholipase C or protein kinase C
36. Ethanol interferes with collagen-induced platelet activation by inhibition of arachidonic acid mobilization
37. Effects of ethanol on pathways of platelet aggregation in vitro
38. In vitro effects of ethanol on rabbit platelet aggregation, secretion of granule contents, and cyclic AMP levels in the presence of prostacyclin
39. Effect of ethanol on platelet phospholipase A2
40. Effect of ethanol on vascular prostacyclin (prostaglandin I2) synthesis, platelet aggregation, and platelet thromboxane release
41. Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol
42. Fibrinogen is an independent marker for thoracic aortic atherosclerosis
43. Contribution of factor VII, fibrinogen and fibrinolytic components to the risk of ischaemic cardiovascular disease: Their genetic determinants
44. Alcohol, coagulation and fibrinolysis
45. The effects of alcohol on coagulation and fibrinolytic factors: A controlled trial
46. Influence of biological factors on lipid and fibrinogen measurements in young men. An epidemiological study in 2009 recruits
47. Associations of fibrinogen, factor VII and PAI-1 with baseline findings among 10,500 male participants in a prospective study of myocardial infarction - The PRIME study. Prospective epidemiological study of myocardial infarction
48. Fibrinogen plasma levels in an apparently healthy general population - Relation to environmental and genetic determinants
49. Fibrinogen: A possible link between alcohol consumption and cardiovascular disease? DESIR study group
50. Effects of moderate consumption of red wine on platelet aggregation and haemostatic variables in healthy volunteers
51. Moderate beer consumption and the blood coagulation in patients with coronary artery disease
52. Haemostatic parameters and lifestyle factors in elderly men in Italy and The Netherlands
53. C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992
54. Alcohol and cytokine networks
55. The effects of acute and chronic alcoholism on tumor necrosis factor and the inflammatory response
56. Alcohol at moderate levels decrease fibrinogen expression in vivo and in vitro
57. Characteristics affecting fibrinolytic activity and plasma fibrinogen concentrations
58. Association of moderate alcohol consumption and plasma concentration of endogenous tissue-type plasminogen activator
59. Effect of moderate dose of alcohol with evening meal on fibrinolytic factors
60. Alcohol consumption and plasminogen activator inhibitor type 1: The National Heart, Lung, and Blood Institute Family Heart Study
61. Urokinase-like plasminogen activator increased in plasma after alcohol drinking
62. Ethyl alcohol enhances plasminogen activator secretion by endothelial cells
63. Ethanol-induced alterations in the expression of endothelial-derived fibrinolytic components
64. Ethanol increases surface-localized fibrinolytic activity in cultured endothelial cells
65. Alcohol-induced upregulation of plasminogen activators and fibrinolytic activity in cultured human endothelial cells
66. Ethanol transcriptionally upregulates t-PA and u-PA gene expression in cultured human endothelial cells
67. Ethanol downregulates transcription of the PAI-1 gene in cultured human endothelial cells
68. Identification of a 251-bp fragment of the PAI-1 gene promoter that mediates the ethanol-induced suppression of PAI-1 expression
69. Ethanol-induced upregulation of candidate plasminogen receptor annexin II in cultured human endothelial cells
70. Ethanol-induced upregulation of urokinase receptor in cultured human endothelial cells
71. Ethanol-induced increased surface-localized fibrinolytic activity in cultured human endothelial cells: Kinectic analysis
72. Activation of guanine nucleotide-binding proteins and induction of endothelial tissue-type plasminogen activator gene transcription by alcohol
73. Risk factors related to ischemic and hemorrhagic cerebrovascular disease at autopsy: The Honolulu Heart Study
74. Alcohol and hemorrhagic stroke. The Honolulu Heart Program
75. Alcohol and stroke. A case-control study of drinking habits past and present
76. Regular light-to-moderate intake of alcohol and the risk of ischemic stroke. Is there a beneficial effect?
77. Light-to-moderate alcohol consumption and risk of stroke among U.S. male physicians
78. The protective effect of moderate alcohol consumption on ischemic stroke
79. Regulation of basal myocardial function by NO
80. Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption
81. Endothelial nitric oxide synthase increases in left atria of dogs with pacing-induced heart failure
82. Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase
83. Infarct size and nitric oxide synthase in murine myocardium
84. The nitric oxide hypothesis of late preconditioning
85. Repetitive myocardial stunning in pigs is associated with the increased expression of inducible and constitutive nitric oxide synthases
86. Regular alcohol consumption mimics cardiac preconditioning by protecting against ischemia-reperfusion injury
87. Over-expressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells
88. Constitutive and inducible hsp70s are involved in oxidative resistance evoked by heat shock or ethanol
89. Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension
90. The pathogenesis of atherosclerosis: A perspective for the 1990s
91. Biological aspects of reactive nitrogen species
92. Regulation of vascular homeostasis by nitric oxide
93. Nitric oxide: From discovery to the clinic
94. Adenoviral gene transfer of nitric oxide synthase: High level expression in human vascular cells
95. Overexpression of endothelium nitric oxide synthase reverses the diminished vasorelaxation in the hindlimb vasculature in ischemic heart failure in vivo
96. Nitric oxide, superoxide and peroxynitrite: The good, the bad and the ugly
97. Improvement of relaxation in an atherosclerotic artery by gene transfer of endothelial nitric oxide synthase
98. Injury-coupled induction of endothelial eNOS and COX-2 genes: A paradigm for thromboresistant gene therapy
99. Enhanced antioxidant activity following chlorination of quercetin by hypochlorous acid
100. eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity
101. Enhanced recovery of injury-caused downregulation of paxillin protein by eNOS gene expression in rat carotid artery. Mechanism of NO inhibition of intimal hyperplasia?
102. Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine
103. The reduction of coronary heart disease with light to moderate alcohol consumption: Effect or artifact?
104. Wine as a biological fluid: History, production, and role in disease prevention
105. Principal phenolic phytochemicals in selected California wines and their antioxidant activity in inhibiting oxidation of human low-density lipoproteins
106. Possible mechanisms for the protective role of antioxidants in wine and plant foods
107. Effect of dietary supplementation of red or white wine on human blood chemistry, hematology and coagulation: Favorable effect of red wine on plasma high-density lipoprotein
108. Effect of the consumption of alcohol, white wine, and red wine on platelet function and serum lipids
109. Wines and grape juices as modulators of platelet aggregation in healthy human subjects
110. Wine: Does the colour count?
111. Effect of red wine consumption on lipoprotein (a) and other risk factors for atherosclerosis
112. Antiatherogenic effects of nonalcoholic ingredients in alcoholic beverages
113. Moderate alcohol consumption and changes in postprandial lipoproteins of premenopausal and postmenopausal women: A diet-controlled, randomized intervention study
114. An enhanced chemiluminescent assay for antioxidant capacity in biological fluids
115. Inhibition of oxidation of low-density lipoprotein with red wine
116. Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation
117. Red wine inhibits the cell-mediated oxidation of LDL and HDL
118. Two glasses of red but not white wine inhibits ex-vivo platelet aggregation and increases bleeding time in human volunteers
119. Effect of red and white wine on serum lipids, platelet aggregation, oxidation products and antioxidants: A preliminary report
120. Platelet rebound effect of alcohol withdrawal and wine drinking in rats. Relation to tannins and lipid peroxidation
121. Platelet functions in relation to dietary fats in farmers from two regions of France
122. Red wine, de-alcoholized red wine of polyphenolics increase fibrinolytic activity in cultured human endothelial cells
123. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation
124. The effect of moderate alcohol consumption as either red or white wine in the C57BL/6 mouse atherosclerosis model
125. Effect of red wine consumption on low-density lipoprotein oxidation and atherosclerosis in aorta and coronary artery in Watanabe heritable hyperlipidemic rabbits
126. Differential effects of alcoholic beverages on experimental atherosclerosis in rabbits
127. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells: A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine
128. Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol
129. Effects of the wine polyphenolics quercetin and resveratrol on pro- inflammatory cytokine expression in RAW 264.7 macrophages
130. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells
131. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-κB
132. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells
133. Red wine polyphenols inhibit proliferation of vascular smooth muscle cells and down-regulate expression of cyclin A gene
134. Gallates inhibit cytokine-induced nuclear translocation of NF-κB and expression of leukocyte adhesion molecules in vascular endothelial cells
135. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin
136. Absorption, distribution, elimination of tea polyphenols in rats
137. Plasma metabolites of quercetin and their antioxidant properties
138. Catechin is present as metabolites in human plasma after consumption of red wine
139. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
140. Inhibition of human LDL oxidation by resveratrol
141. Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines
142. Non-alcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations
143. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease
144. Interference of some flavonoids and non-steroidal anti-inflammatory drugs with oxidative metabolism of arachidonic acid by human platelets and neutrophils
145. Antiplatelet activity of cis-resveratrol
146. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
147. Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin
148. Inhibition in vitro of platelet aggregation and arachidonic acid metabolism by flavone
149. The tissue factor pathway: How it has become a "prima ballerina"
150. Tissue factor in the pathogenesis of atherosclerosis
151. Tissue factor in health and disease
152. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal antihuman tissue factor antibody
153. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque
154. Polyphenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells
155. Resveratrol promotes atherosclerosis in hypercholesterolemic rabbits
156. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury
157. Selective inhibition of separated forms of cyclic nucleotide phosphodiesterase from rat heart by some pentasubstituted quercetin analogs
158. Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties
159. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta
160. Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta
161. Effect of red wine on endothelium-dependent relaxation in rabbits
162. Mechanism of endothelial nitric oxide-dependent vasorelaxation induced by wine polyphenols in rat thoracic aorta
163. Effects of red and white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries
164. Antioxidant polyphenols in tea, cocoa, and wine
165. Effect of quercetin on platelet aggregation induced by oxyradicals
166. Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols
167. Quercetin metabolites inhibit copper ion-induced lipid peroxidation in rat plasma
168. Chlorination and nitration of soy isoflavones
169. Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis)
170. Dietary flavonoids as antioxidants in vivo: Conjugated metabolites of (-)-epicatechin and quercetin participate in antioxidative defense in blood plasma
171. The vascular protective effects of estrogen
172. Protection from myocardial reperfusion injury by acute administration of 17 beta-estradiol
173. Partial and weak oestrogenicity of the red wine constituent resveratrol: Consideration of its superagonist activity in MCF-7 cells and its suggested cardiovascular protective effects
174. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
175. Is resveratrol an estrogen agonist in growing rats?