Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase

Circulation

Volumn 101, Issue 23, 2000, Pages 2742-2748

  Kanno, Shinichi ^a   Lee, Paul C ^b   Zhang, Yuqing ^a   Ho, Chien ^a   Griffith, Bartley P ^b   Shears II, Larry L ^b   Billiar, Timothy R ^b  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Hemodynamics; Ischemia; Nitric oxide; Nitric oxide synthase; Reperfusion

Indexed keywords

N ACETYL S NITROSOPENICILLAMINE; N5 (1 IMINOETHYL)ORNITHINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 0034643875     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.23.2742     Document Type: Article

References (38)

1. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev. 1991;43:109-142.
2. Forstermann U, Closs EI, Pollock JS, et al. Nitric oxide synthase isozymes: characterization, purification, molecular cloning, and functions. Hypertension. 1994;23:1121-1131.
3. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987;327:524-526.
4. Stuehr DJ, Cho HJ, Kwon NS, et al. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc Natl Acad Sci USA. 1991;88:7773-7777.
5. Schulz R, Nava E, Moncada S. Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium. Br J Pharmacol. 1992;105:575-580.
6. Lowenstein CJ, Alley EW, Raval P, et al. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc Natl Acad Sci USA. 1993;90:9730-9734.
7. McGowan FX Jr, Davis PJ, del Nido PJ, et al. Endothelium-dependent regulation of coronary tone in the neonatal pig. Anesth Analg. 1994;79:1094-1101.
8. Radomski MW, Palmer RM, Moncada S. The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br J Pharmacol. 1987;92:639-646.
9. Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A. 1991;88:4651-4655.
10. Groves PH, Lewis MJ, Cheadle HA, et al. SIN-1 reduces platelet adhesion and platelet thrombus formation in a porcine model of balloon angioplasty. Circulation. 1993;87:590-597.
11. Radomski MW, Palmer RM, Moncada S. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet. 1987;2:1057-1058.
12. Finkel MS, Oddis CV, Jacob TD, et al. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 1992;257:387-389.
13. Balligand JL, Kelly RA, Marsden PA, et al. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci U S A. 1993;90:347-351.
14. Mizuno T, Watanabe M, Sakamoto T, et al. L-Arginine, a nitric oxide precursor, attenuates ischemia-reperfusion injury by inhibiting inositol-1,4,5-triphosphate. J Thorac Cardiovasc Surg. 1998;115:931-936.
15. Lefer DJ, Nakanishi K, Johnston WE, et al. Antineutrophil and myocardial protecting actions of a novel nitric oxide donor after acute myocardial ischemia and reperfusion of dogs. Circulation. 1993;88:2337-2350.
16. Beresewicz A, Karwatowska-Prokopczuk E, Lewartowski B, et al. A protective role of nitric oxide in isolated ischaemic/reperfused rat heart. Cardiovasc Res. 1995;30:1001-1008.
17. Das DK, Kalfin R, Maulik N, et al. Coordinated role of vasoactive intestinal peptide and nitric oxide in cardioprotection. Ann N Y Acad Sci. 1998;865:297-308.
18. Weyrich AS, Ma XL, Lefer AM. The role of L-arginine in ameliorating reperfusion injury after myocardial ischemia in the cat. Circulation. 1992;86:279-288.
19. Yoshida K, Mizukami Y, Kitakaze M. Nitric oxide mediates protein kinase C isoform translocation in rat heart during postischemic reperfusion. Biochim Biophys Acta. 1999;1453:230-238.
20. Jones SP, Girod WG, Palazzo AJ, et al. Myocardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase. Am J Physiol 1999;276:H1567-H1573.
21. Xi L, Jarrett NC, Hess ML, et al. Essential role of inducible nitric oxide synthase in monophosphoryl lipid A-induced late cardioprotection: evidence from pharmacological inhibition and gene knockout mice. Circulation. 1999;99:2157-2163.
22. Parrino PE, Laubach VE, Gaughen JR Jr, et al. Inhibition of inducible nitric oxide synthase after myocardial ischemia increases coronary flow. Ann Thorac Surg. 1998;66:733-739.
23. Wang P, Zweier JL. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart: evidence for peroxynitrite-mediated reperfusion injury. J Biol Chem. 1996;271:29223-29230.
24. Flögel U, Decking UK, Gödecke A, et al. Contribution of NO to ischemia-reperfusion injury in the saline-perfused heart: a study in endothelial NO synthase knockout mice. J Mol Cell Cardiol. 1999;31:827-836.
25. Igarashi J, Nishida M, Hoshida S, et al. Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes. Am J Physiol. 1998;274:C245-C252.
26. Woolfson RG, Patel VC, Neild GH, et al. Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism. Circulation. 1995;91:1545-1551.
27. Shesely EG, Maeda N, Kim HS, et al. Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1996;93:13176-13181.
28. MacMicking JD, Nathan C, Hom G, et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell. 1995;81:641-650.
29. Lee PC, Salyapongse AN, Bragdon GA, et al. Impaired wound healing and angiogenesis in eNOS-deficient mice. Am J Physiol. 1999;277: H1600-H1608.
30. Gödecke A, Decking UK, Ding Z, et al. Coronary hemodynamics in endothelial NO synthase knockout mice. Circ Res. 1998;82:186-194.
31. Yoshida T, Maulik N, Engelman RM, et al. Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury. Circulation. 1997;96(suppl):II-216-II-220.
32. Nossuli TO, Hayward R, Jensen D, et al. Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury. Am J Physiol. 1998;275:H509-H519.
33. Loke KE, McConnell PI, Tuzman JM, et al. Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption. Circ Res. 1999;84:840-845.
34. Leist M, Single B, Naumann H, et al. Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis. Exp Cell Res. 1999;249:396-403.
35. Shen W, Hintze TH, Wolin MS. Nitric oxide: an important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption. Circulation. 1995;92:3505-3512.
36. Recchia FA, McConnell PI, Bernstein RD, et al. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res. 1998;83:969-979.
37. 2+ channels by S-nitrosothiol nitric oxide donors. Circ Res. 1997;81:742-752.
38. Loihl AK, Whalen S, Campbell IL, et al. Transcriptional activation following cerebral ischemia in mice of a promoter-deleted nitric oxide synthase-2 gene. J Biol Chem. 1999;274:8844-8849