Type III cyclic nucleotide phosphodiesterases and insulin action

Current Topics in Cellular Regulation

Volumn 34, Issue C, 1996, Pages 63-100

  Manganiello, Vincent C ^a   Degerman, Eva ^c   Taira, Masato ^a,b   Kono, Tetsuro ^d   Belfrage, Per ^c  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c LUND UNIVERSITY   (Sweden)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP PHOSPHODIESTERASE; GLUCAGON; INSULIN; ISOENZYME; PHOSPHODIESTERASE; PROTEIN KINASE; TRIACYLGLYCEROL LIPASE;

ADIPOSE TISSUE; ANIMAL; BIOLOGICAL MODEL; CLASSIFICATION; DRUG ANTAGONISM; ENZYME SPECIFICITY; GENETICS; GLYCOGEN LIVER LEVEL; LIPOLYSIS; LIVER; MAMMAL; METABOLISM; MOLECULAR CLONING; MULTIGENE FAMILY; PHYSIOLOGY; REVIEW; SECOND MESSENGER; THROMBOCYTE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADENYLATE CYCLASE; ADIPOSE TISSUE; ANIMALS; BLOOD PLATELETS; CLONING, MOLECULAR; CYCLIC AMP; CYCLIC GMP; GLUCAGON; INSULIN; ISOENZYMES; LIPASE; LIPOLYSIS; LIVER; LIVER GLYCOGEN; MAMMALS; MODELS, BIOLOGICAL; MULTIGENE FAMILY; PHOSPHORIC DIESTER HYDROLASES; PROTEIN KINASES; SECOND MESSENGER SYSTEMS; SUBSTRATE SPECIFICITY;

EID: 0029691755     PISSN: 00702137     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0070-2137(96)80003-3     Document Type: Article

References (267)

1. Edelman A.M., Blumenthal D.K., and Krebs E.G. Annu. Rev. Biochem. 56 (1987) 567-613
2. Taylor S.S., Buechler J.A., and Yonemoto W. Annu. Rev. Biochem. 59 (1990) 971-1005
3. Shabb J., and Corbin J.D. J. Biol. Chem. 267 (1992) 5723-5726
4. Kaupp U.B. Trends Neurosci. 14 (1991) 150-157
5. Dhallan R.S., Yau K.-W., Schrader K.R., and Reed R.R. Nature (London) 347 (1990) 184-187
6. Charbonneau H., Prusti R.K., LeTrong H., Sonnenburg W.K., Mullaney P.J., Walsh K.A., and Beavo J.A. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 288-292
7. Francis S.H., Lincoln T.M., and Corbin J.D. J. Biol. Chem. 255 (1990) 620-626
8. Beavo J.A., Conti M., and Heaslip R.J. Mol. Pharmacol. 46 (1994) 399-405
9. Beavo J.A., and Houslay M.H. Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England
10. Beavo J.A. Adv. Second Messengers Phosphoprotein Res. 22 (1988) 1-38
11. Beavo J.A., and Reifsnyder D.H. Trends Pharmacol. Sci. 11 (1990) 150-156
12. Conti M., Jim C.S.L., Monaco L., Repaske D.R., and Swinnen J.V. Endocr. Rev. 12 (1991) 218-234
13. Nicholson C.D., Challis R.A.J., and Sahid M. Trends Pharmacol. Sci. 12 (1991) 19-27
14. Thompson W.J. Pharmacol. Ther. 51 (1991) 13-33
15. Torphy T.J., and Undem B.J. Thorax 46 (1991) 512-523
16. Giembycz M.A. Biochem. Pharmacol. 43 (1992) 2041-2051
17. Giembycz M.A., and Dent G. Clin. Exp. Allergy 22 (1992) 337-344
18. Hall I.P. Br. J. Clin Pharmacol. 35 (1993) 1-7
19. Wang J.H., Sharma R.K., and Mooibroek M.J. In: Beavo J., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterase: Structure, Regulation, and Drug Action (1990), Wiley, Chichester, England 19-60
20. Kincaid R.L., Balaban C.D., and Billingsley M.L. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 1118-1122
21. Manganiello V.C., Tanaka T., and Murashima S. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England 61-86
22. Martins T.J., Mumby M.C., and Beavo J.A. J. Biol. Chem. 257 (1982) 1973-1979
23. Yamamoto T., Manganiello V.C., and Vaughan M. J. Biol. Chem. 258 (1983) 12526-12533
24. MacFarland R.T., Zelus B.D., and Beavo J.A. J. Biol. Chem. 266 (1991) 136-142
25. Manganiello V.C., Smith C.J., Degerman E., and Belfrage P. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England 87-140
26. Degerman E., Belfrage P., Newman A.H., Rice K.C., and Manganiello V.C. J. Biol. Chem. 262 (1987) 5797-5807
27. Harrison S.A., Reifsnyder D.H., Gallis B., Cadd C.G., and Beavo J.A. Mol. Pharmacol. 25 (1986) 506-514
28. Colucci W.S., Wright R.F., and Braunwald E. N. Engl. J. Med. 314 (1986) 290-299
29. Colucci W.S., Wright R.F., and Braunwald E. N. Engl. J. Med. 314 (1986) 349-358
30. Weishaar R.E., Cain M.H., and Bristol J.A. J. Med. Chem. 28 (1985) 537-545
31. Wetzel B., and Hauel N. Trends Pharmacol. Sci. 9 (1988) 166-170
32. Conti M., and Swinnen J.V. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure Regulation and Drug Action (1990), Wiley, Chichester, England 243-267
33. Yamamoto T., Lieberman F., Osborne Jr. J.C., Manganiello V.C., Vaughn M., and Hidaka H. Biochemistry 23 (1984) 670-675
34. Reeves M.L., Leigh B.K., and England P.J. Biochem. J. 241 (1987) 535-541
35. Swinnen J.V., Joseph D.R., and Conti M. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 8197-8201
36. Henkel-Tiggs J., and Davis R.L. Mol. Pharmacol. 37 (1990) 7-10
37. Torphy T.J., Stadel J.M., Burman M., Cieslinski L.B., McLaughlin M.M., White J.R., and Livi G.P. J. Biol. Chem. 267 (1992) 1798-1804
38. Francis S.H., Thomas M.K., and Corbin J.D. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England 117-140
39. Gillespie P.G. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England 165-185
40. Hamet P., and Coquil J.F. J. Cyclic Nucleotide Res. 4 (1978) 281-290
41. Thomas M.K., Francis S.H., and Corbin J.D. J. Biol. Chem. 265 (1990) 14964-14970
42. Yamazaki A., Sen I., Bitenski M.W., Casnellie J.E., and Greengard P. J. Biol. Chem. 255 (1980) 11619-11624
43. Gillepsie P.G., and Beavo J.A. J. Biol. Chem. 263 (1988) 8133-8141
44. Arshavsky V.Y., Dumke C.L., and Bownds M.D. J. Biol. Chem. 267 (1992) 24501-24507
45. Lugnier C., Scoeffter P., LeBec A., Strouthon E., and Stoclet J.C. Biochem. Pharmacol. 35 (1986) 1743-1751
46. Gillepsie P.G., and Beavo J.A. Mol. Pharmacol. 36 (1989) 773-781
47. Charbonneau H. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action (1990), Wiley, Chichester, England 267-298
48. Charbonneau H., Beier N., Walsh K.A., and Beavo J.A. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 9308-9312
49. Charbonneau H., Kumar S., Novack J.B., Blumenthal D.K., Griffin P.R., Shabanowitz J., Hunt D.F., Beavo J.A., and Walsh K.A. Biochemistry 30 (1991) 7931-7940
50. Bentley J.K., Kadlecek A., Sherbert C.H., Seger D., Sonnenberg W.K., Charbonneau H., Novack J.P., and Beavo J.A. J. Biol. Chem. 267 (1992) 18676-18682
51. Sonnenberg W.K., Seger K., and Beavo J.A. J. Biol. Chem. 268 (1993) 645-652
52. Repaske D.R., Swinnen J.V., Jin S.-L.C., VanWyk J.J., and Conti M. J. Biol. Chem. 267 (1992) 18683-18688
53. Polli J.W., and Kincaid R.L. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11079-11083
54. Trong H.L., Beir N., Sonnenberg W.K., Stroop S.D., Walsh K.A., Beavo J.A., and Charbonneau H. Biochemistry 29 (1990) 10280-10288
55. Sonnenburg W.K., Mullaney P.J., and Beavo J.A. J. Biol. Chem. 266 (1991) 17655-17661
56. Tanaka T., Hockman S., Moos Jr. M., Taira M., Meacci E., Murashima S., and Manganiello V.C. Second Messengers Phosphoproteins 13 (1991) 87-98
57. Meacci E., Taira M., Moos Jr. M., Smith C.J., Movsesian M.A., Degerman E., Belfrage P., and Manganiello V.C. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 3721-3725
58. Taira M., Hockman S., Calvo J.C., Taira M., Belfrage P., and Manganiello V.C. J. Biol. Chem. 268 (1993) 18573-18579
59. Chen C.N., Denome S., and Davis R.L. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 9313-9317
60. Swinnen J.V., Joseph D.R., and Conti M. Proc. Natl. Acad. Sci. U.S.A. 86 (1988) 5325-5329
61. Colicelli J., Birchmeier C., Michaeli T., O'Neill K., Riggs M., and Wigler M. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 3599-3603
62. Livi G., Kmetz P., McHale M.M., Cieslinski L.B., Sathe G.M., Taylor D.P., Davis R.L., Torphy T.J., and Balcarek J.M. Mol. Cell. Biol. 10 (1990) 2678-2686
63. McLaughlin M., Cieslinski L.B., Burman M., Torphy T.J., and Livi G. J. Biol. Chem. 268 (1993) 6470-6476
64. Ovchinnikov Y.A., Gubanov V.V., Khramtsov N.V., Ischenko K.A., Zagranichny V.E., Muradov K.G., Shiwaeva T.M., and Lipkin V.M. FEBS Lett. 233 (1987) 169-173
65. Li T., Volpp K., and Applebury M.L. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 293-297
66. Lipkin V.M., Khramtsov N.V., Vasilevskaya I.A., Atabekova N.V., Muradov K.G., Guvanov V.V., Li T., Johnston J.P., Volpp K.J., and Applebury M.J. J. Biol. Chem. 265 (1990) 12955-12959
67. McAllister L.M., Kadlecek A.T., Sonnenberg W.T., Seger D., Le Trong H., Colbran J.L., Thomas M.K., Walsh K.A., Francis S.H., Corbin J.D., and Beavo J.A. J. Biol. Chem. 268 (1993) 22863-22873
68. Oppert B., Cunnick J.M., Hurt D., and Takemoto D.J. J. Biol. Chem. 266 (1991) 16607-16613
69. Anant J.S., Ong O.C., Xie H., O'Brien P.J., and Fung B.K.K. J. Biol. Chem. 267 (1992) 687-690
70. Michaeli T., Bloom T.J., Martins T., Loughney K., Ferguson K., Riggs M., Rodgers L., Beavo J.A., and Wigler M. J. Biol. Chem. 268 (1993) 12925-12932
71. Polson J.B., Krzanowski J.J., and Szentivanyi A. Biochem. Pharmacol. 34 (1985) 1875-1879
72. Torphy T.J., Burman M., Huang L.B.F., and Tucker S.S. J. Pharmacol. Exp. Ther. 246 (1988) 843-850
73. Torphy T.J., Zhou H.-L., Burman M., and Huang L.B.F. Mol. Pharmacol. 39 (1991) 376-384
74. Bristol J.A., Secar J., Moos W.H., Evans D.B., and Weishaar R.E. J. Med. Chem. 27 (1984) 1099-1101
75. Weishaar R.E., Kobylarz-Singer D.C., Steffen N.P., and Kaplan H.R. Circ. Res. 61 (1987) 539-547
76. Kauffman R.F., Crowe V.G., Utterback B.G., and Robertson D. Mol. Pharmacol. 30 (1987) 609-616
77. Bethke T., Briankhorst D., von der Leyen H., Meyer W., Nigbur R., and Scholz H. Naunyn-Schmiedeberg's Arch. Pharmacol. 337 (1988) 576-582
78. Challis R.A.J., and Nicholson C.D. Br. J. Pharmacol. 100 (1990) 47-53
79. Dent G., Giembycz M.A., Rabe K.F., and Barnes P.J. Br. J. Pharmacol. 103 (1991) 1339-1346
80. Souness J.E., Carter C.M., Diocee B.K., Hassal G.A., Wood L.J., and Turner N.C. Biochem. Pharmacol. 42 (1991) 937-945
81. Lindgren S., Rascon A., Andersson K.-E., Manganiello V.C., and Degerman E. Biochem. Pharmacol. 42 (1991) 545-552
82. Harris A.L., Connell M.J., Ferguson E.W., Wallace A.M., Gordon R.J., Pagani E.D., and Silva P. J. Pharmacol. Exp. Ther. 251 (1989) 199-206
83. Peachell P.T., Undem B.J., Schleimer R.P., MacGlashan Jr. D.W., Lichtenstein L.M., Cieslinski L.B., and Torphy T.J. J. Immunol. 148 (1992) 2503-2510
84. Robicsek S.A., Krzanowski J.J., Szentivanyi A., and Polson J.B. Biochem. Pharmacol. 42 (1991) 869-877
85. Souness J.E., Hassal G.A., and Parrott D.P. Biochem. Pharmacol. 44 (1992) 857-866
86. Colucci W. Cardiol. Rev. 1 (1993) 42-49
87. Meeker R.B., and Harden T.K. Mol. Pharmacol. 22 (1982) 310-319
88. Meeker R.B., and Harden T.K. Mol. Pharmacol. 23 (1983) 384-392
89. Tanner L.I., Harden T.K., Wells J.N., and Martin M.W. Mol. Pharmacol. 29 (1986) 455-463
90. Whalin, M. W., Strada, S. J., Scammell, J. G., and Thompson, W. J. (1990). In "Purines in Cellular Signalling: Targets for New Drugs." (K. A. Jacobson, J. W. Daly, and V. Manganiello, eds.), pp. 323-328.
91. Maurice D.H., and Haslam R.J. Mol. Pharmacol. 37 (1990) 671-681
92. Houslay M.D., and Kilgour E. In: Beavo J.A., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure Regulation and Drug Action (1990), Wiley, Chichester, England 185-227
93. Bowes C., Li T., Danciger M., Baxter L.C., Applebury M.L., and Farber D.B. Nature (London) 347 (1990) 677-680
94. Pittler S.J., and Baehr W. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 8322-8326
95. Lem J., Flannery J.G., Li T., Applebury M.L., Farber D.B., and Simon M.I. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 4422-4426
96. Degerman E., Manganiello V.C., Newman A.H., Rice K.C., and Belfrage P. Adv. Second Messengers Phosphoprotein Res. 12 (1988) 171-182
97. Grant D., and Colman R.W. Biochemistry 23 (1984) 1801-1807
98. Degerman E., Moos Jr. M., Rascon V., Vasta V., Meacci E., Smith C.J., Lindgren S., Andersson K.-E., Belfrage P., and Manganiello V.C. Biochim. Biophys. Acta 1205 (1995) 189-198
99. Pyne N., Cooper M., and Houslay M.D. Biochem. J. 242 (1987) 33-42
100. Boyes S., and Loten E.G. Eur. J. Biochem. 174 (1988) 303-309
101. Rascon A., Lindgren S., Stavenow L., Belfrage P., Andersson K.-E., Manganiello V.C., and Degerman E. Biochim. Biophys. Acta 1134 (1992) 149-152
102. Alvarez R., Banerjee G.L., Bruno J.J., Jones G.L., Littschwager K., Strossberg A., and Venuti M.C. mol. Pharmacol. 29 (1986) 554-560
103. Komas N., Lugnier C., LeBec A., Serradeil-LeGal C., Barthelemy G., and Stoclet J.C. J. Cardiovasc. Pharmacol. 14 (1989) 213-220
104. Hidaka H., and Endo T. Adv. Cyclic Nucleotide Res. 16 (1984) 245-259
105. Silver P.J., Lepore R.E., O'Connor B., Lemp B.M., Hamel L.T., Bentley R.G., and Harris A.L. J. Pharmacol. Exp. Ther. 247 (1988) 34-42
106. Brechler V., Pavoine C., Hanf R., Garbarz E., Fischmeister R., and Pecker F. J. Biol. Chem. 267 (1992) 15496-15501
107. LeBon T.R., Kasuya J., Paxton R.J., Belfrage P., Hockman S., Manganiello V.C., and Fujitayamaguchi Y. Endocrinology (Baltimore) 130 (1992) 3265-3274
108. Degerman E., Smith C.J., Tornqvist H., Vasta V., Belfrage P., and Manganiello V.C. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 533-537
109. Smith C.J., Vasta V., Degerman E., Belfrage P., and Manganiello V.C. J. Biol. Chem. 266 (1991) 13385-13390
110. MacPhee C.H., Harrison S.A., and Beavo J.A. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 6660-6663
111. Grant P.G., Mannarino A.F., and Colman R.W. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 9071-9075
112. Smith C.J., Krall J., Manganiello V.C., and Movsesian M.A. Biochem. Biophys. Res. Commun. 190 (1993) 516-521
113. Loten E.G., and Sneyd J.G.T. Biochem. J. 120 (1970) 187-193
114. Manganiello V.C., and Vaughan M. J. Biol. Chem. 248 (1973) 7164-7170
115. Kono T., Robinson F.W., and Sarver J.A. J. Biol. Chem. 250 (1975) 7827-7835
116. Sakai T., Thompson W.J., Lavis R., and Williams R.H. Arch. Biochem. Biophys. 142 (1974) 331-339
117. Zinman B., and Hollenberg C.H. J. Biol. Chem. 249 (1974) 2182-2187
118. Elks M.E., Manganiello V.C., and Vaughan M. J. Biol. Chem. 258 (1983) 8582-8587
119. Pawlson L.G., Lovell-Smith C.J., Manganiello V.C., and Vaughan M. Proc. Natl. Acad. Sci. U.S.A. 71 (1974) 1639-1642
120. Makino H., and Kono T. J. Biol. Chem. 255 (1980) 7850-7854
121. Weber H.W., and Appleman M.M. J. Biol. Chem. 257 (1982) 5339-5341
122. Beavo J. In: Beavo J., and Houslay M.D. (Eds). Cyclic Nucleotide Phosphodiesterases: Structure, Regulation, and Drug Action Vol. 2 (1990), Wiley, Chichester, England 3-19
123. Smith C.J., and Manganiello V.C. Mol. Pharmacol. 35 (1989) 381-386
124. Gettys T.W., Blackmore P., Redmon J.E., Beebe S.J., and Corbin J.D. J. Biol. Chem. 262 (1987) 333-339
125. Gettys T.W., Vine A.J., Simonds M.F., and Corbin J.D. J. Biol. Chem. 263 (1988) 10359-10363
126. Anderson N.G., Kilgour E., and Houslay M.D. Biochem. J. 262 (1989) 867-872
127. (Abst). Smith C.J., Shibata H., Robinson F., Belfrage P., Kono T., and Manganiello V.C. FASEB J. 6 (1992) A430
128. Shibata H., Robinson F.W., Soderling T.R., and Kono T. J. Biol. Chem. 266 (1991) 17948-17953
129. Loten E.G., Assimacopoulis-Jeannet F.D., Exton J.H., and Park C.R. J. Biol. Chem. 253 (1978) 746-757
130. Heyworth C.M., Wallace A.V., and Houslay M.D. Biochem. J. 214 (1983) 99-110
131. Allan E.G., and Sneyd J.G.T. Biochem. Biophys. Res. Commun. 62 (1975) 594-601
132. Marchmont R.J., Ayad S.R., and Houslay M.D. Biochem. J. 195 (1981) 645-652
133. Pyne N.J., Anderson N., Lavan B.E., Milligan G., Nimmo H.G., and Houslay M.D. Biochem. J. 234 (1987) 325-334
134. Benelli C., Desbuquois S., and DeGallo B. Eur. J. Biochem. 156 (1986) 211-220
135. Corbin J.D., Beebe S.J., and Blackmore P.F. J. Biol. Chem. 260 (1985) 8731-8735
136. Kilgour E., Anderson N.G., and Houslay M.D. Biochem. J. 260 (1989) 27-36
137. Hidaka H., Hayashi H., Kohri H., Kimura Y., Hosokawa T., Igawa T., and Saitoh Y. J. Pharmacol. Exp. Ther. 211 (1979) 26-30
138. Lopez-Aparicio P., Rascon A., Manganiello V.C., Andersson K.E., Belfrage P., and Degerman E. Biochem. Biophys. Res. Commun. 186 (1992) 517-523
139. Macphee C.H., Reifsnyder D.H., Moore T.A., Levea K.M., and Beavo J.A. J. Biol. Chem. 263 (1988) 10353-10358
140. Walseth T.F., Gander J.E., Eide S.J., Krick T.P., and Goldberg N.D. J. Biol. Chem. 258 (1983) 1544-1559
141. Leiser M., Fleischer N., and Erlichman J. J. Biol. Chem. 261 (1986) 15486-15490
142. Butcher R.W., Sneyd J.G.T., Park C.R., and Sutherland E.W.J. J. Biol. Chem. 241 (1966) 1651-1653
143. Kono T., and Barham F.W. J. Biol. Chem. 248 (1973) 7417-7426
144. Jefferson L.S., Exton J.H., Butcher R.W., Sutherland E.W., and Park C.R. J. Biol. Chem. 243 (1968) 1031-1038
145. Pilkis S.J., Claus T.H., Johnson R.A., and Park C.R. J. Biol. Chem. 250 (1975) 6328-6336
146. Heyworth C.M., and Houslay M.D. Biochem. J. 214 (1983) 547-552
147. Wong E.H.A., and Loten E.G. Eur. J. Biochem. 115 (1981) 17-22
148. Londos C., Honnor R.C., and Dhillon G.S. J. Biol. Chem. 260 (1985) 15139-15145
149. Francis S., and Kono T. Mol. Cell. Biochem. 42 (1982) 109-116
150. Elks M.E., and Manganiello V.C. Endocrinology (Baltimore) 116 (1985) 2119-2121
151. Makino H., Suzuki T., Kajinuma H., Yamazaki M., Ito H., and Yoshida S. Adv. Second Messengers Phosphoprotein Res. 25 (1992) 185-199
152. Schmitz-Peifer C., Reeves M.L., and Denton R.M. Cell. Signall. 4 (1992) 37-49
153. Cicirelli M.F., Pelech S.L., and Krebs E.G. J. Biol. Chem. 263 (1988) 2009-2019
154. Sadler S.E., and Maller J.L. J. Biol. Chem. 264 (1989) 856-861
155. Sadler S.E. Mol. Endocrinol. 5 (1991) 1939-1946
156. Sadler S.E. Mol. Endocrinol. 5 (1991) 1947-1954
157. Low M.G., and Saltiel A.R. Science 239 (1988) 268-275
158. Saltiel A.R. Endocrinology (Baltimore) 120 (1987) 967-972
159. Kiechle F.L., and Jarrett L. FEBS Lett. 133 (1981) 279-282
160. Kelly K.L., Mato J.M., Merida I., and Jarrett L. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 6404-6407
161. Misek D.E., and Saltiel A.R. J. Biol. Chem. 267 (1992) 16266-16273
162. Beebe S.J., Redmon J.B., Blackmore P.F., and Corbin J.D. J. Biol. Chem. 260 (1985) 15781-15788
163. Kono T., Robinson F.W., Sarver J.A., Vega F.V., and Pointer R.H. J. Biol. Chem. 252 (1977) 2226-2233
164. Rascon A., Degerman E., Taira M., Meacci E., Smith C.J., Manganiello V.C., Belfrage P., and Tornqvist H. J. Biol. Chem. 269 (1994) 11962-11966
165. Shibata H., and Kono T. Biochem. Biophys. Res. Commun. 167 (1990) 614-620
166. Lopez-Aparicio P., Belfrage P., Manganiello V.C., Kono T., and Degerman E. Biochem. Biophys. Res. Commun. 193 (1993) 1137-1144
167. Shibata H., and Kono T. Biochem. Biophys. Res. Commun. 170 (1990) 533-539
168. Czech M., Klarlund J.D., Yagaloff K.A., Bradford A.P., and Lewis R.E. J. Biol. Chem. 263 (1988) 11017-11020
169. Lovell-Smith C.J., Manganiello V.C., and Vaughan M. Biochim. Biophys. Acta 497 (1977) 447-458
170. Strewler G.J., and Manganiello V.C. J. Biol. Chem. 254 (1979) 11891-11898
171. Loten E.G., Francis S.H., and Corbin J.D. J. Biol. Chem. 255 (1980) 7838-7844
172. Makino H., de Buschiazzo P.M., Pointer R.H., Jordan J.E., and Kono T. J. Biol. Chem. 255 (1980) 7845-7849
173. Macaulay S.L., Kiechle F.L., and Jarret L. Arch. Biochem. Biophys. 225 (1983) 130-136
174. Ueda M., Robinson F.W., Smith M.W., and Kono T. J. Biol. Chem. 259 (1984) 9520-9525
175. Souness J.E., Thompson W.J., and Strada S.J. J. Cyclic Nucleotide Phosphorylation Res. 10 (1985) 383-396
176. Robinson F.W., Smith C.J., Flanagan J.E., Shibata H., and Kono T. J. Biol. Chem. 264 (1989) 16458-16464
177. Thompson W.J., Tan B.-H., and Strada S.J. J. Biol. Chem. 266 (1991) 17011-17019
178. Ueki H., Okuhama R., Sera M., Inone T., Tominaga N., and Moreta T. Endocrinology (Baltimore) 131 (1992) 441-446
179. Carpenedo F., and Floreani M. Biochem. Biophys Res. Commun. 190 (1993) 609-615
180. Rosen O.M. Science 237 (1987) 1452-1458
181. Taylor S.I. Diabetes 41 (1992) 1473-1490
182. Lawrence Jr. J.C. Annu. Rev. Physiol. 54 (1992) 177-193
183. Pelech S.L., and Sanghera J.S. Trends Biochem. Sci. 17 (1992) 233-238
184. Cobb M.H., Boulton T.G., and Robbins D.J. Cell Regul. 2 (1991) 965-978
185. Nishida E., and Gotoh Y. Trends Biochem. Sci. 18 (1993) 128-135
186. Boulton T.G., Nye S.H., Robbins D.J., Ip N.Y., Radziejewska E., Morgenbesser S.D., DePinho R.A., Panayotatos N., Cobb M.H., and Yancopoulos G.D. Cell 65 (1991) 663-675
187. Roberts T. Nature (London) 360 (1992) 534-535
188. Blenis J. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 5889-5892
189. Sturgill T.W., Ray L.B., Erikson E., and Maller J.L. Nature (London) 334 (1988) 715-718
190. Ahn N.G., and Krebs E.G. J. Biol. Chem. 265 (1990) 11495-11504
191. Pulverer B.J., Kyriakis J.M., Avruch J., Nikolakaki E., and Woodgett J.R. Nature (London) 353 (1991) 670-674
192. Alvarez E., Northwood I.C., Gonzalez F.A., Latour D.A., Seth A., Abate C., Curran T., and Davis R.J. J. Biol. Chem. 266 (1991) 15277-15285
193. Seth A., Alvarez E., Gupta S., and Davis R.J. J. Biol. Chem. 266 (1991) 23521-23524
194. Chen R.-H., Sarnecki C., and Blenis J. Mol. Cell. Biol. 12 (1992) 915-927
195. Baker S.J., Kerppola T.K., Luk D., Vandenberg M.T., Marshak D.R., Curran T., and Abate C. Mol. Cell. Biol. 12 (1992) 4694-4705
196. Erikson R.L. J. Biol. Chem. 266 (1991) 6007-6010
197. Thomas G. Cell 68 (1992) 3-6
198. Ballou L.M., Luther H., and Thomas G. Nature (London) 349 (1991) 348-350
199. Blenis J., Chung J., Erikson E., Alcorta D., and Erikson D.L. Cell Growth Differ. 2 (1991) 279-285
200. Chung J., Kao C., Crabtree G., and Blenis J. Cell 69 (1992) 1227-1236
201. Anderson N.G., Maller J.L., Tonks N.K., and Sturgill T.W. Nature (London) 343 (1990) 651-653
202. Seger R., Ahn N.G., Posada J., Munar E.S., Jensen A.M., Cooper J.A., Cobb M.H., and Krebs E.G. J. Biol. Chem. 267 (1992) 14373-14381
203. Ahn N.G., Seger R., and Krebs E.G. Curr. Opinion Cell Biol. 4 (1992) 992-999
204. Thomas S.M., DeMarco M., D'Arcangelo G., Halegoria S., and Brugge J.S. Cell 68 (1992) 1031-1040
205. Wood K.W., Sarnecki C., Roberts T.M., and Blenis J. Cell 68 (1992) 1041-1050
206. deVries-Smits A.M.M., Burgering B.M.M., Leevers S.J., Marshall C.J., and Bos J.C. Nature (London) 357 (1992) 602-605
207. Gallego C., Gupta S.K., Heasley L.E., Qian K.-L., and Johnson G.L. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 7355-7359
208. Gupta S.K., Gallego C., Johnson G.L., and Heasley L.E. J. Biol. Chem. 267 (1992) 7987-7990
209. Kyriakis J.M., App H., Zhang X.-F., Banerjee P., Brautigan D.L., Rapp U.R., and Avruch J. Nature (London) 358 (1992) 417-421
210. Dent P., Haser W., Haystead T.A.J., Vincent L.A., Roberts T.M., and Sturgill T.W. Science 257 (1992) 1404-1407
211. Howe L.R., Leevers S.J., Gomez N., Nakielny S., Cohen P., and Marshall C.J. Cell 71 (1992) 335-342
212. Lange-Carter C.A., Pleiman C.M., Gardner A.M., Blumer K.J., and Johnson G.L. Science 260 (1993) 315-319
213. Crews C.M., and Erikson R.L. Cell 74 (1993) 215-217
214. Ullrich A., and Schlessinger J. Cell 61 (1990) 203-212
215. Satoh T., Nakafuku M., and Kaziro Y. J. Biol. Chem. 267 (1992) 24149-24152
216. Kaziro Y., Itoh H., Kozasa T., Nakafuku M., and Satoh T. Annu. Rev. Biochem. 60 (1991) 349-400
217. Heidecker G., Kolch N., Morrison D.K., and Rapp U.R. Adv. Cancer Res. 58 (1992) 53-73
218. Burgering B.M.T., Medema R.H., Maassen J.A., vande Wetering M.L., vander Erb A.J., McCormick F., and Bos J.L. EMBO J. 10 (1991) 1103-1109
219. Medema R.H., deVries Smits A.M.M., Vander Zon G.C.M., Maassen J.A., and Bos J.L. Mol. Cell. Biol. 13 (1993) 155-162
220. Osterop A.P.M., Medema R.H., Bos J.L., vanderZon G.C.M., Moller D.E., Flier J.S., Moller E., and Maassen J.A. J. Biol. Chem. 267 (1992) 14647-14653
221. Porras A., Nebreda A.R., Benito M., and Santos E. J. Biol. Chem. 267 (1992) 21124-21131
222. Pronk G.J., Medina R.H., Burgering B.M.T., Clark R., McCormick F., and Bos J.L. J. Biol. Chem. 267 (1992) 24058-24062
223. Hattori S., Fukuda M., Yamashita T., Nakamura S., Gotoh Y., and Nishida E. J. Biol. Chem. 267 (1992) 20346-20351
224. Pomerance M., Schweighoffer F., Tocque B., and Pierre M. J. Biol. Chem. 267 (1992) 16155-16160
225. Robbins D.J. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 6924-6928
226. Kolch W., Heidecker G., Lloyd P., and Rapp U.R. Nature (London) 349 (1991) 426-428
227. Zhang X.-F., Settleman J., Kyriakis J.M., Takeuchi-Suzuki E., Elledge S.J., Marshall M.S., Bruder J.T., Rapp U.R., and Avruch J. Nature (London) 364 (1993) 308-313
228. Warne P.H., Viciana P.R., and Downward J. Nature (London) 364 (1993) 352-354
229. Myers Jr. M., and White M.F. Diabetes 43 (1993) 643-650
230. Sun X.J., Miralpeix M., Myers M.G., Glasheen E.M., Backer J.M., Kahn C.R., and White M.F. J. Biol. Chem. 267 (1992) 22662-22672
231. Sun X.J., Rothenberg P., Kahn C.R., Backer J.M., Araki E., Wilden P., Cahill D.A., Goldstein B.J., and White M.F. Nature (London) 352 (1991) 73-77
232. Shoelson S.E., Chatterjee S., Chaudhuri M., and White M.F. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 2027-2031
233. Backer J.M., Schroeder G.G., Cahill D.A., Ullrich A., Siddle K., and White M. Biochemistry 300 (1991) 6366-6372
234. Backer J.M., Myers Jr. M.G., Sun X.J., Chin D.J., Shoelson S.E., Miralpeix M., and White M.F. J. Biol. Chem. 268 (1993) 8204-8212
235. Pawson T., and Gish G.D. Cell 71 (1992) 359-362
236. Ruderman N., Kapellis R., White M.F., and Cantley L.C. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 1411-1415
237. Cantley L.C., Auger K.R., Carpenter C., Duckworth B., Kapeller R., and Soltoff S. Cell 64 (1991) 281-302
238. Pazin M.J., and Williams L.T. Trends Biochem. Sci. 17 (1992) 374-378
239. Lowenstein E.J., Daly R.J., Batzer A.G., Li W., Margolis B., Lammers R., Ullrich A., Skolnik E.Y., Bar-Sagi D., and Schlessinger J. Cell 70 (1992) 431-442
240. Skolnik E.Y., Batzer A., Li N., Lee C.-H., Lowenstein E., Mohammedi M., Margolis B., and Schlessinger J. Science 260 (1993) 1953-1955
241. Baltensperger K., Kozma L., Cherniack A.D., Klarlund J., Chawla A., Banerjee U., and Czech M.P. Science 260 (1993) 1950-1952
242. Williams N.G., Roberts T.M., and Li P. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 2922-2926
243. Lee R.M., Cobb M.H., and Blackshear P.J. J. Biol. Chem. 267 (1992) 1088-1092
244. Matsuda S., Gotoh Y., and Nishida E. J. Biol. Chem. 268 (1993) 3277-3281
245. Egan J.J., Saltis J., Wek S.A., Simpson I.A., and Londos C. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 1052-1056
246. Blackshear P.J., Haupt D.M., and Stumpo D.J. J. Biol. Chem. 266 (1991) 10946-10952
247. Farese R.V., Standaert M.L., Arnold T., Yu B., Ishizuka T., Hoffman J., Vila M., and Cooper D. Cell. Signall. 4 (1992) 133-143
248. Chen J.E., Dickens M., Tavares J., and Roth R.R. J. Biol. Chem. 268 (1993) 6338-6347
249. Lavoinne A., Erikson E., Maller J., Price D.J., Avruch J., and Cohen P. Eur. J. Biochem. 199 (1991) 723-728
250. Dent P., Lavoinne A., Nakialny S., Caudwell F.B., Watt P., and Cohen P. Nature (London) 348 (1990) 302-308
251. Cohen P., and Cohen P.T.W. J. Biol. Chem. 264 (1989) 21435-21438
252. Holm C., Kirchgessner T.G., Svenson K.L., Fredrickson G., Nilsson S., Millar C.G., Shively J.E., Heinzmann C., Sparkes R.S., Mohandas T., Lasis A.J., Belfrage P., and Schotz M.C. Science 241 (1988) 1503-1506
253. Belfrage P., Donner J., Eriksson H., and Stralfors P. In: Belfrage P., Donner J., and Stralfors P. (Eds). Mechanisms of Insulin Action (1986), Elsevier, Amsterdam 323-340
254. Stralfors P., Bjorgell P., and Belfrage P. Proc. Natl. Acad. Sci. U.S.A. 81 (1984) 3317-3321
255. Iliano G., and Cuatrecasas P. Science 174 (1972) 906-908
256. Hepp K.O., and Renner R. FEBS Lett. 20 (1972) 191-194
257. Heyworth C.M., and Houslay M.D. Biochem. J. 214 (1983) 547-552
258. Ashby C.D., and Walsh D.A. J. Biol. Chem. 247 (1972) 6638-6642
259. Larner J. J. Cyclic Nucleotide Res. 8 (1982) 289-296
260. Denton R.M., Tavare J.M., Borthwick A., Dickins M., Diggle T.A., Edgell N., Heeson K.J., Issad T., Lynch D.F., Moule S.K., Schmitz-Pfeiffer C., and Welsh G.I. Biochem. Soc. Trans. 20 (1992) 659-664
261. Makino H., Manganiello V.C., and Kono T. Annu. Rev. Physiol. 56 (1994) 273-295
262. Denton R.M., and Tavare J.M. Eur. J. Biochem. 227 (1995) 597-611
263. Okada T., Sakuma L., Fukui Y., Hazeki O., and Ui M. J. Biol. Chem. 269 (1994) 3563-3567
264. Uehara T., Tokumitsu Y., and Nomura Y. Biochem. Biophys. Res. Commun. 210 (1995) 574-580
265. Rahn T., Ridderstrale M., and Tornqvist H. FEBS Lett. 350 (1994) 314-318
266. Cheatham B., Vlahoz C.J., Cheatham L., Wang L., Blenis J., and Kahn C.R. Mol. Cell. Biol. 14 (1994) 4902-4911
267. In press. Degerman E., Leroy M.-J., Taira M., Belfrage P., and Manganiello V.C. In: LeRoith D., Olefsky J.M., and Taylor S. (Eds). Diabetes Mellitus: A Fundamental and Clinical Text (1995), Lippincott, Philadelphia