메뉴 건너뛰기




Volumn 59, Issue 12, 2000, Pages 1106-1117

Cholesterol is sequestered in the brains of mice with Niemann-Pick Type C disease but turnover is increased

Author keywords

Apolipoprotein E; Demyelination; Endosomes; Low density lipoprotein receptor; Lysosomes; Neurodegeneration

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MYELIN; PROTEIN; VERY LOW DENSITY LIPOPROTEIN;

EID: 0034534808     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/59.12.1106     Document Type: Article
Times cited : (100)

References (68)
  • 3
    • 0000815355 scopus 로고
    • Niemann-Pick disease type C: A cellular cholesterol lipidosis
    • Scriver CR, Beaudet AL, Sly WS, et al, eds. The metabolic and molecular bases of inherited diseases. 7th ed. New York: McGraw-Hill
    • (1995) , pp. 2625-2639
    • Pentchev, P.G.1    Vanier, M.T.2    Suzuki, K.3    Patterson, M.C.4
  • 14
    • 0032892536 scopus 로고    scopus 로고
    • Lipid changes in Niemann-Pick disease Type C brain: Personal experience and review of the literature
    • (1999) Neurochem Res , vol.24 , pp. 481-489
    • Vanier, M.T.1
  • 15
  • 16
    • 0028268018 scopus 로고
    • The two-receptor model of lipoprotein clearance: Tests of the hypothesis in 'knockout' mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4431-4435
    • Ishibashi, S.1    Herz, J.2    Maeda, N.3
  • 17
    • 0029808272 scopus 로고    scopus 로고
    • Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor apolipoprotein E, or both
    • (1996) J Biol Chem , vol.37 , pp. 22422-22427
    • Ishibashi, S.1    Perrey, S.2    Chen, Z.3
  • 19
    • 0032030919 scopus 로고    scopus 로고
    • Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B 100
    • (1998) J Clin Invest , vol.101 , pp. 1084-1093
    • Boren, J.1    Lee, I.2    Zhu, W.3
  • 26
    • 0002995671 scopus 로고    scopus 로고
    • What the Niemann-Pick type C gene has taught us about cholesterol transport
    • Chang T-Y, Freeman DA, eds. Intracellular cholesterol trafficking. Norwell, MA: Kluwer Academic Publishers
    • (1998) , pp. 93-107
    • Neufeld, E.B.1
  • 32
  • 33
    • 0033548442 scopus 로고    scopus 로고
    • Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice
    • (1999) J Biol Chem , vol.274 , pp. 7165-7171
    • Ueda, Y.1    Royer, L.2    Gong, E.3
  • 51
    • 0021118229 scopus 로고
    • Regulation of low density lipoprotein uptake and degradation in different animals species
    • Parnham MJ, Brune K, eds. Agents and actions supplements. Stuttgart: Birkhauser Verlag
    • (1984) , pp. 177-190
    • Dietschy, J.M.1    Spady, D.K.2
  • 53
    • 17344366169 scopus 로고    scopus 로고
    • Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition
    • (1998) J Neurosci , vol.18 , pp. 5673-5681
    • Cheng, C.M.1    Joncas, G.2    Reinhardt, R.R.3
  • 56
    • 0034733750 scopus 로고    scopus 로고
    • Embryonic striatal neurons from Niemann-Pick type C mice exhibit defect in cholesterol metabolism and neurotrophin responsiveness
    • (2000) J Biol Chem , vol.275 , pp. 20179-20187
    • Henderson, L.P.1    Lin, L.2    Prasad, A.3
  • 59
    • 0029958248 scopus 로고    scopus 로고
    • Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein
    • (1996) J. Biol. Chem. , vol.271 , pp. 30121-30125
    • Fagan, A.M.1    Bu, G.2    Sun, Y.3
  • 64
  • 65
    • 0014770106 scopus 로고
    • The measurement of the exchangeable pools of cholesterol in the baboon
    • (1970) J Clin Invest , vol.49 , pp. 655-665
    • Wilson, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.