Sources of cholesterol during development of the rat fetus and fetal organs

Journal of Lipid Research

Volumn 38, Issue 4, 1997, Pages 723-733

  Jurevics, Helga A ^a   Kidwai, Faisal Z ^a   Morell, Pierre ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

brain; cholesterol biosynthesis; placenta; uterus

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL SYNTHESIS; FETUS; FETUS DEVELOPMENT; GESTATIONAL AGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID ANALYSIS; NONHUMAN; ORGAN WEIGHT; ORGANOGENESIS; PRIORITY JOURNAL; RADIOACTIVITY; RAT; STOICHIOMETRY; TISSUE LEVEL;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CHOLESTEROL; DECIDUA; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GESTATIONAL AGE; HEART; KIDNEY; LIVER; LUNG; MYOCARDIUM; ORGAN SIZE; PLACENTA; PREGNANCY; RATS; UTERUS;

EID: 0030957561     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. 14C into rabbit and guinea pig fetus. J. Lipid Res. 8: 558-564.
2. Pitkin, R. M., W. E. Connor, and D. S. Lin. 1972. Cholesterol metabolism and placental transfer in the pregnant rhesus monkey. J. Clin. Invest. 51: 2584-2592.
3. Woollett, L. A. 1996. Origin of cholesterol in the fetal Golden Syrian hamster: contribution of de novo sterol synthesis and maternal-derived lipoprotein cholesterol. J. Lipid Res. 37: 1246-1257.
4. Spady, D. K., and J. M. Dietschy. 1983. Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat. J. Lipid Res. 24: 303-315.
5. Dietschy, J. M., and D. K. Spady. 1984. Measurement of rates of cholesterol synthesis using tritiated water. J. Lipid Res. 25: 1469-1476.
6. Belknap, W. M., and J. M. Dielschy. 1988. Sterol synthesis and low density lipoprotein clearance in vivo in the pregnant rat, placenta, and fetus. Sources for tissue cholesterol during fetal development. J. Clin. Invest. 82: 2077-2085.
7. Irons, M., E. R. Elias, G. Salen, G. S. Tint, and A. K. Batta. 1993. Defective cholesterol biosynthesis in Smith-Lemli-Opitz syndrome. Lancet. 341: 1414.
8. Tint, G. S., M. Irons, E. R. Elias, A. K. Batta, R. Frieden, T. S. Chen, and G. Salen. 1994. Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. N. Engl. J. Med. 330: 107-113.
9. Opitz, J. M., and F. de la Cruz. 1994. Cholesterol metabolism in the RSH/Smith-Lemli-Opitz syndrome: summary of an NICHD Conference. Am. J. Med. Genet. 50: 326-338.
10. Salen, G., S. Shefer, A. K. Batta, G. S. Tint, G. Xu, A. Honda, M. Irons, and E. R. Elias. 1996. Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome. J. Lipid Res. 37: 1169-1180.
11. Folch, J. M., M. Lees, and G. H. Sloane Stanley. 1957. A simple method for the isolation and purification of total WMF lipids from animal tissues. J. Biol. Chem. 226: 497-509.
12. Benjamins, J. A., A. L. Miller, and P. Morell. 1976. Metabolic relationships between myelin subfractions: entry of galactolipids and phospholipids. J. Neurochem. 27: 565-570.
13. Jurevics, H. A., and P. Morell. 1994. Sources of cholesterol for kidney and nerve during development. J. Lipid Res. 35: 112-120.
14. Jurevics, H. A., and P. Morell. 1995. Cholesterol for synthesis of myelin is made locally, not imported into brain. J. Neurochem. 64: 895-901.
15. Lakshmanan, M. R., and R. L. Veech. 1977. Measurement of of rate of rat liver sterol synthesis in vivo using tritiated water. J. Biol. Chem. 252: 4667-4673.
16. Morton, A. J., and D. F. Goldspink. 1986. Changes in protein turnover in rat uterus during pregnancy. Am. J. Physiol. 250: E114-E120.
17. Afting, E. G., M. L. Becker, and J. S. Elce. 1979. Proteinase and proteinase inhibitor activities of rat uterine myometrium during pregnancy and involution. J. Biochem. 177: 99-106.
18. Scott, J. N., and P. B. Pendergrass. 1981. Scanning electron microscopy of the decidual stalk and decidua basalis in the mouse. Anat. Embryol. 162: 435-441.
19. Neary, R. H., M. D. Kilby, P. Kumpatula, F. L. Game, D. Bhatnagar, P. N. Durrington, and P. M. S. O'Brien. 1995. Fetal and maternal lipoprotein metabolism in human pregnancy. Clin. Sci. 88: 311-318.
20. Innis, S. M., and N. C. Haave. 1988. Effect of chronic modification of diet fat and cholesterol during gestation on plasma hormones and hepatic enzyme activities in rat fetus. Biol. Neonate. 53: 355-361.
21. Goldwater, W. H., and D. Stetten, Jr. 1947. Studies in fetal metabolism. J. Biol. Chem. 169: 723-738.
22. Naoum, H. G., R. C. de-Chazal, B. M. Eaton, and S. F. Contractor. 1987. Characterization and specificity of lipoprotein binding to term human placental membranes. Biochim. Biophys. Acta. 902: 193-199.
23. Whittmaack, F. M., M. E. Gafvels, M. Bronner, H. Matsuo, K. R. McCrae, J. E. Tomaszewski, S. L. Robinson, D. K. Strickland, and J. F. Strauss III. 1995. Localization and regulation of the human very low density lipoprotein/ apolipoprotein-E receptor: trophoblast expression predicts a role for the receptor in placental lipid transport. Endocrinology. 136: 340-348.
24. Linn, D. S., R. M. Pitkin, and W. E. Connor. 1977. Placental transfer of cholesterol into the human fetus. J. Obstet. Gynaecol. 128: 735-736.
25. Demmer, L. A., M. S. Levin, J. Elovson, M. A. Reuben, A. J. Lusis, and J. I. Gordon. 1986. Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene. Proc. Natl. Acad. Sci. USA. 83: 8102-8106.
26. Plonne, D., L. Winkler, H. Franke, and R. Dargel. 1992. The visceral yolk sac - an important site of synthesis and secretion of apolipoprotein B-containing lipoproteins in the feto-placental unit of the rat. Biochim. Biophys. Acta. 1127: 174-185.
27. Farese, R. V., Jr., S. Cases, S. L. Ruland, H. J. Kayden, J. S. Wong, S. G. Young, and R. L. Hamilton. 1996. A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. J. Lipid Res. 37: 347-360.
28. Albreght, E. D., and G. J. Pepe. 1990. Placental steroid hormone biosynthesis in primate pregnancy. Endocr. Rev. 11: 124-150.
29. Knopp, R. H., M. R. Warth, D. Charles, M. Childs, J. R. Li, H. Mabuchi, and M. I. VanAllen. 1986. Lipoprotein metabolism in pregnancy, fat transport to the fetus, and the effects of diabetes. Biol. Neonate. 50: 297-317.
30. Hay, W. W., Jr. 1994. Placental transport of nutrients to the fetus. Horm. Res. 42: 215-222.
31. Hay, W. W., Jr. 1995. Current topic: metabolic interrelationships of placenta and fetus. Placenta. 16: 19-30.
32. Brent, R. L., A. J. Johnson, and M. Jensen. 1971. The production of congenital malformations using tissue antisera. Teratology. 4: 255-276.
33. Farese, R. V., Jr., S. L. Ruland, L. M. Flynn, R. P. Stokowski, and S. G. Young. 1995. Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA. 92: 1774-1778.
34. Huang, L., E. Voyiaziakis, D. F. Markenson, K. A. Sokol, T. Hayek, and J. L. Breslow. 1995. ApoB gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apoA-I transport rates in heterozygotes. J. Clin. Invest. 96: 2152-2161.
35. Edmond, J., R. A. Korsak, J. W. Morrow, G. Torok-Both, and D. H. Catlin. 1991. Dietary cholesterol and the origin of cholesterol in the brain of developing rats. J. Nutr. 121: 1323-1330.
36. Turley, S. D., D. K. Burns, C. R. Rosenfeld, and J. M. Dietschy. 1996. Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep. J. Lipid Res. 37: 1953-1961.
37. Levin, M. S., A. J. A. Pitt, A. L. Schwartz, P. A. Edwards, and J. I. Gordon. 1989. Developmental changes in the expression of genes involved in cholesterol biosynthesis and lipid transport in human and rat fetal and neonatal livers. Biochim. Biophys. Acta. 1003: 293-300.
38. Ness, G. C., J. P. Miller, M. H. Moffler, L. S. Woods, and H. B. Harris. 1979. Perinatal development of 3-hydroxy-3-methylglutaryl cocnzyme A reductase activity in rat lung, liver and brain. Lipids. 14: 447-450.