Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription

Journal of Virology

Volumn 72, Issue 7, 1998, Pages 5626-5637

  Schang, Luis M ^a   Phillips, Joanna ^a   Schaffer, Priscilla A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; MEVINOLIN; OLOMOUCINE; ROSCOVITINE; STAUROSPORINE; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL FUNCTION; CELL PROLIFERATION; DNA REPLICATION; DRUG ACTIVITY; DRUG CYTOTOXICITY; GENE EXPRESSION; HERPES SIMPLEX VIRUS; NONHUMAN; PRIORITY JOURNAL; VERO CELL; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0031746015     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.7.5626-5637.1998     Document Type: Article

References (63)

1. Abraham, R. T., M. Acquarone, A. Andersen, A. Asensi, R. Belle, F. Berger, C. Bergounioux, G. Brunn, C. Buquet-Fagot, D. Fagot, et al. 1995. Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases. Biol. Cell 83: 105-120.
2. Becker, Y., Y. Asher, Y. Cohen, E. Weinberg-Zahlering, and J. Shlomai. 1977. Phosphonoacetic acid-resistant mutants of herpes simplex virus: effect of phosphonoacetic acid on virus replication and in vitro deoxyribonucleic acid synthesis in isolated nuclei. Antimicrob. Agents Chemother. 11:919-922.
3. Berns, J. I. 1996. Parvoviridae: the viruses and their replication, p. 2173-2197. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
4. Bresnahan, W. A., I. Boldogh, P. Chi, E. A. Thompson, and T. Albrecht. 1997. Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication. Virology 231:239-247.
5. Cai, W., and P. A. Schaffer. 1991. A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1. J. Virol. 65:4078-4090.
6. - mutants of herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 92:10516-10520.
7. Cole, C. N. 1996. Polyomavirinae: the viruses and their replication, p. 1997-2025. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
8. Cooper, J., J. Conner, and J. B. Clements. 1995. Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase. J. Virol. 69:4979-4985.
9. Crissman, H. A., D. M. Gadbois, R. A. Tobey, and E. M. Bradbury. 1991. Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle. Proc. Natl. Acad. Sci. USA 88:7580-7584.
10. Daksis, J. I., and C. M. Preston. 1992. Herpes simplex virus immediate early gene expression in the absence of transinduction by Vmw65 varies during the cell cycle. Virology 189:196-202.
11. De Azevedo, W. F., S. Leclerc, L. Meijer, L. Havlicek, M. Strnad, and S. H. Kim. 1997. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur. J. Biochem. 243:518-526.
12. DePamphilis, M. 1996. DNA replication in eukaryotic cells. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
13. Dudley, D. T., L. Pang, S. J. Decker, A. J. Bridges, and A. R. Saltiel. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92:7686-7689.
14. Dynlacht, B. 1997. Regulation of transcription by proteins that control the cell cycle. Nature 389:149-152.
15. Elliott, G., D. O'Reilly, and P. O'Hare. 1996. Phosphorylation of the herpes simplex virus type 1 tegument protein VP22. Virology 226:140-145.
16. Glab, N., B. Labidi, L. X. Qin, C. Trehin, C. Bergounioux, and L. Meijer. 1994. Olomoucine, an inhibitor of the cdc2/cdk2 kinases activity, blocks plant cells at the G1 to S and G2 to M cell cycle transitions. FEBS Lett. 353:207-211.
17. Gold, M. O., J. P. Tassan, E. A. Nigg, A. P. Rice, and C. H. Herrmann. 1996. Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic Acids Res. 24:3771-3777.
18. Goldstein, D. J., and S. K. Weller. 1988. Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant. Virology 166:41-51.
19. Goto, H., S. Motomura, A. C. Wilson, R. N. Freiman, Y. Nakabeppu, K. Fukushima, M. Fujishima, W. Heir, and T. Nishimoto. 1997. A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. Genes Dev. 11:726-737.
20. Graves, R., R. Davies, G. Brophy, G. O'Beirne, and N. Cook. 1997. Noninvasive, real-time method for the examination of thymidine uptake events -application of the method to V-79 cell synchrony studies. Anal. Biochem. 248:251-257.
21. Grenfell, S. J., D. S. Latchman, and N. S. Thomas. 1996. Oct-1 and Oct-2 DNA-binding site specificity is regulated in vitro by different kinases. Biochem. J. 315:889-893.
22. Hay, J., and J. H. Subak-Sharpe. 1976. Mutants of herpes simplex virus types 1 and 2 that are resistant to phosphonoacetic acid induce altered DNA polymerase activity. J. Gen. Virol. 31:145-148.
23. Hilton, M. J., D. Mounghane, T. McLean, N. V. Contractor, J. O'Neil, K. Carpenter, and S. L. Bachenheimer. 1995. Induction by herpes simplex virus of free and heteromeric forms of E2F transcription factor. Virology 213:624-638.
24. Honess, R. W., and D. H. Watson. 1977. Herpes simplex virus resistance and sensitivity to phosphonoacetic acid. J. Virol. 21:584-600.
25. Hossain, A., T. Holt, J. Ciacci-Zanella, and C. Jones. 1997. Analysis of cyclin-dependent kinase activity after herpes simplex virus type 2 infection. J. Gen. Virol. 78:3341-3348.
26. Iseki, H., T. C. Ko, X. Y. Xue, A. Seapan, M. R. Hellmich, and C. M. Townsend, Jr. 1997. Cyclin-dependent kinase inhibitors block proliferation of human gastric cancer cells. Surgery 122:187-194.
27. Jamieson, A. T., G. A. Gentry, and J. H. Subak-Sharpe. 1974. Induction of both thymidine and deoxycytidine kinase activity by herpes viruses. J. Gen. Virol. 24:465-480.
28. Jofre, J. T., P. A. Schatter, and D. S. Parris. 1977. Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1. J. Virol. 23:833-836.
29. Jordan, R., J. Pepe, and P. A. Schaffer. 1998. Characterization of a nerve growth factor-inducible cellular activity that enhances herpes simplex virus type 1 gene expression and replication of an ICPO null mutant in cells of neural lineage. J. Virol. 72:5373-5382.
30. Jordan, R., and P. A. Schaffer. 1997. Activation of gene expression by herpes simplex virus type 1 ICP0 occurs at the level of mRNA synthesis. J. Virol. 71: 6850-6862.
31. Kawaguchi, Y., C. Van Sant, and B. Roizman. 1997. Herpes simplex virus 1 α regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J. Virol. 71:7328-7336.
32. Keyomarsi, K., L. Sandoval, V. Band, and A. B. Pardee. 1991. Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin. Cancer Res. 51:3602-3609.
33. Knipe, D. M. 1996. Virus-host cell interactions, p. 273-299. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
34. Kristie, T. M., and P. A. Sharp. 1993. Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16). J. Biol. Chem. 268:6525-6534.
35. Kwon, Y. G., S. Y. Lee, Y. Choi, P. Greengard, and A. C. Nairn. 1997. Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proc. Natl. Acad. Sci. USA 94:2168-2173.
36. Malecz, N., R. Foisner, C. Stadler, and G. Wiche. 1996. Identification of plectin as a substrate of p34cdc2 kinase and mapping of a single phosphorylation site. J. Biol. Chem. 271:8203-8208.
37. McGeoch, D., B. Barnett, and C. McLean. 1993. Emerging functions of alphaherpesvirus genes. Semin. Virol. 4:125-134.
38. Meyer, L., A. Borgne, O. Mulner, J. P. Chong, J. J. Blow, N. Inagaki, M. Inagaki, J. G. Delcros, and J. P. Moulinoux. 1997. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem. 243:527-536.
39. Meisner, H., and M. P. Czech. 1991. Phosphorylation of transcriptional factors and cell-cycle-dcpendent proteins by casein kinase II. Curr. Opin. Cell Biol. 3:474-483.
40. Mitchell, C., J. A. Blaho, and B. Roizman. 1994. Casein kinase II specifically nucleotidylylates in vitro the amino acid sequence of the protein encoded by the alpha 22 gene of herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 91: 11864-11868.
41. Nicholas, J., K. Cameron, and R. Honess. 1992. Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclins. Nature 355:362-365.
42. O'Hare, P. 1993. The virion transactivator of herpes simplex virus. Semin. Virol. 4:145-156.
43. O'Reilly, D., O. Hanscombe, and P. O'Hare. 1997. A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II. EMBO J. 16:2420-2430.
44. Omura, S., Y. Sasaki, Y. Iwai, and H. Takeshima. 1995. Staurosporine, a potentially important gift from a microorganism. J. Antibiot. 48:535-548.
45. Overby, L., E. Robishaw, J. Schleicher, A. Reuter, N. Shipkowitz, and J.-H. Mao. 1974. Inhibition of herpes simplex virus replication by phosphonoacetic acid Antimicrob. Agents Chemother. 6:360-365.
46. Rice, S., M. Long, V. Lam, and C. Spencer. 1994. RNA polymerase II is aberrantly phosphorylated and localized to viral replication compartments following herpes simplex virus infection. J. Virol. 68:988-1001.
47. Roberts, S. B., N. Segil, and N. Heintz. 1991. Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science 253:1022-1026.
48. Roy, R. J. P. Adamczewski, T. Seroz, W. Venneulen, J. P. Tassan, L. Schaeffer, E. A. Nigg, J. H. Hoeijmakers, and J. M. Egly. 1994. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell 79: 1093-1101.
49. Rüeg, U., and G. Burgess. 1989. Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol. Sci. 10:218-220.
50. Schaffer, P. A., G. M. Aron, N. Biswal, and M. Benyesh-Melnick. 1973. Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization. Virology 52:57-71.
51. Schang, L. M., G. F. Kutish, and F. A. Osorio. 1994. Correlation between precolonization of trigeminal ganglia by attenuated strains of pseudorabies virus and resistance to wild-type virus latency. J. Virol. 68:8470-8476.
52. Schang, L. M., and P. A. Schaffer. Unpublished data.
53. Schulze-Gahmen, U., J. Brandsen, H. D. Jones, D. O. Morgan, L. Meijer, J. Vesely, and S. H. Kim. 1995. Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. Proteins 22:378-391.
54. Shadan, F. F., L. M. Cowsert, and L. P. Villarreal. 1994. n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. J. Virol. 68:4785-4796.
55. Smith, R. L., L. I. Pizer, E. M. Johnson, Jr., and C. L. Wilcox. 1992. Activation of second-messenger pathways reactivates latent herpes simplex virus in neuronal cultures. Virology 188:311-318.
56. Umene, K., and T. Nishimoto. 1996. Inhibition of generation of authentic genomic termini of herpes simplex virus type 1 DNA in temperature-sensitive mutant BHK-21 cells with a mutated CCG1/TAF(II)250 gene. J. Virol. 70:9008-9012.
57. van den Heuvel, S., and E. Harlow. 1993. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262:2050-2054.
58. Vesely, J., L. Havlicek, M. Strnad, J. J. Blow, A. Donella-Deana, L. Pinna, D. S. Letham, J. Kato, L. Detivaud, S. Leclere, et al. 1994. Inhibition of cyclin-dependent kinases by purine analogues. Eur. J. Biochem. 224:771-786.
59. Wieprecht, M., T. Wieder, C. Paul, C. C. Geilen, and C. E. Orfanos. 1996. Evidence for phosphorylation of CTP:phosphocholine cytidylyltransferase by multiple proline-directed protein kinases. J. Biol. Chem. 271:9955-9961.
60. Wilcock, D., and D. P. Lane. 1991. Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells. Nature 349:429-431.
61. Wilson, A. C., R. N. Freiman, H. Goto, T. Nishimoto, and W. Herr. 1997. VP16 targets an amino-terminal domain of HCF involved in cell cycle progression. Mol. Cell. Biol. 17:6139-6146.
62. Yanagi, K., A. Talavera, T. Nishimoto, and M. G. Rush. 1978. Inhibition of herpes simplex virus type 1 replication in temperature-sensitive cell cycle mutants. J. Virol. 25:42-50.
63. Yura, Y., J. Kusaka, H. Tsujimoto, Y. Yoshioka, H. Yoshida, and M. Sato. 1997. Effects of protein tyrosine kinase inhibitors on the replication of herpes simplex virus and the phosphorylation of viral proteins. Intervirology 40:7-14.