메뉴 건너뛰기




Volumn 6, Issue 3, 2000, Pages 773-781

Expression of ERCC1 antisense RNA abrogates gemcitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; CISPLATIN; COMPLEMENTARY RNA; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DRUG METABOLITE; GEMCITABINE; HYGROMYCIN;

EID: 0034059127     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (91)

References (61)
  • 1
    • 0033559213 scopus 로고    scopus 로고
    • An investigational new drug treatment program for patients with gemcitabine: Results for over 3000 patients with pancreatic carcinoma
    • Phila.
    • Storniolo, A. M., Enas, N. H., Brown, C. A., Voi, M., Rothenberg, M. L., and Schilsky, R. An investigational new drug treatment program for patients with gemcitabine: results for over 3000 patients with pancreatic carcinoma. Cancer (Phila.), 85: 1261-1268, 1999.
    • (1999) Cancer , vol.85 , pp. 1261-1268
    • Storniolo, A.M.1    Enas, N.H.2    Brown, C.A.3    Voi, M.4    Rothenberg, M.L.5    Schilsky, R.6
  • 2
    • 0033028673 scopus 로고    scopus 로고
    • Gemcitabine: Single-agent and combination therapy in non-small cell lung cancer
    • Sandler, A., and Ettinger, D. S. Gemcitabine: single-agent and combination therapy in non-small cell lung cancer. Oncologist, 4: 241-251, 1999.
    • (1999) Oncologist , vol.4 , pp. 241-251
    • Sandler, A.1    Ettinger, D.S.2
  • 4
    • 0030686593 scopus 로고    scopus 로고
    • Gemcitabine: A promising new agent in the treatment of advanced urothelial cancer
    • Moore, M. J., Tannock, I. F., Ernst, D. S., Huan, S., and Murray, N. Gemcitabine: a promising new agent in the treatment of advanced urothelial cancer. J. Clin. Oncol., 15: 3441-3445, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3441-3445
    • Moore, M.J.1    Tannock, I.F.2    Ernst, D.S.3    Huan, S.4    Murray, N.5
  • 5
    • 0030722875 scopus 로고    scopus 로고
    • Clinical response benefit in patients with advanced pancreatic cancer. Role of gemcitabine
    • Carmichael, J. Clinical response benefit in patients with advanced pancreatic cancer. Role of gemcitabine. Digestion, 58: 503-507, 1997.
    • (1997) Digestion , vol.58 , pp. 503-507
    • Carmichael, J.1
  • 9
    • 0033015208 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine in refractory germ cell tumors
    • Einhorn, L. H., Stender, M. J., and Williams, S. D. Phase II trial of gemcitabine in refractory germ cell tumors. J. Clin. Oncol., 17: 509-511, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 509-511
    • Einhorn, L.H.1    Stender, M.J.2    Williams, S.D.3
  • 14
    • 0029593648 scopus 로고
    • Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts
    • Braakhuis, B. J., Ruiz van Haperen, V. W., Welters, M. J., and Peters, G. J. Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts. Eur. J. Cancer, 31A: 2335-2340, 1995.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 2335-2340
    • Braakhuis, B.J.1    Ruiz Van Haperen, V.W.2    Welters, M.J.3    Peters, G.J.4
  • 16
    • 0019131198 scopus 로고
    • Correlation of cytotoxicity with incorporation of ara-C into DNA
    • Kufe, D. W., Major, P. P., Egan, E. M., and Beardsley, G. P. Correlation of cytotoxicity with incorporation of ara-C into DNA. J. Biol. Chem., 255: 8997-8900, 1980.
    • (1980) J. Biol. Chem. , vol.255 , pp. 8997-18900
    • Kufe, D.W.1    Major, P.P.2    Egan, E.M.3    Beardsley, G.P.4
  • 17
    • 0025130572 scopus 로고
    • Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine: A mechanism for cytotoxicity
    • Huang, P., Chubb, S, and Plunkett, W. Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine: A mechanism for cytotoxicity. J. Biol. Chem., 265: 16617-16625, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16617-16625
    • Huang, P.1    Chubb, S.2    Plunkett, W.3
  • 18
    • 0026324313 scopus 로고
    • Action of 2′, 2′-difluorodeoxycytidine on DNA synthesis
    • Huang P., Chubb, S., Hertel, L. W., Gnndey, G. B., and Plunkett, W. Action of 2′, 2′-difluorodeoxycytidine on DNA synthesis. Cancer Res., 57: 6110-6117, 1991.
    • (1991) Cancer Res. , vol.57 , pp. 6110-6117
    • Huang, P.1    Chubb, S.2    Hertel, L.W.3    Gnndey, G.B.4    Plunkett, W.5
  • 19
    • 0028062981 scopus 로고
    • Molecular effects of 2′,2′-difluorodeoxycytidine (gemcitabine) on DNA replication in tact HL-60 cells
    • Ross, D. D., and Cuddy, D. P. Molecular effects of 2′,2′-difluorodeoxycytidine (gemcitabine) on DNA replication in tact HL-60 cells. Biochem. Pharmacol., 48: 1619-1630, 1994.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1619-1630
    • Ross, D.D.1    Cuddy, D.P.2
  • 20
    • 0029060757 scopus 로고
    • Fludarabine- And gemcitabine-induced apoptosis: Incorporation of analogs into DNA is a critical event
    • Huang, P., and Plunkett, W. Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother. Pharmacol., 36: 181-188, 1995.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 181-188
    • Huang, P.1    Plunkett, W.2
  • 21
    • 0021343977 scopus 로고
    • Lethal effects of 1-β-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair
    • Kufe, D. W., Weichselbaum, R., Egan, E. M., Dahlberg, W., and Fram, R. J. Lethal effects of 1-β-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair. Mol. Pharmacol., 25: 322-326, 1984.
    • (1984) Mol. Pharmacol. , vol.25 , pp. 322-326
    • Kufe, D.W.1    Weichselbaum, R.2    Egan, E.M.3    Dahlberg, W.4    Fram, R.J.5
  • 22
    • 0029019181 scopus 로고
    • Arabinosyl-2-fluoroadenine augments cisplatin cytotoxicity and inhibits cisplatin-DNA cross-link repair
    • Yang, L.-Y., Li, L., Keating, M. J., and Plunkett, W. Arabinosyl-2-fluoroadenine augments cisplatin cytotoxicity and inhibits cisplatin-DNA cross-link repair. Mol. Pharmacol., 47: 1072-1079, 1995.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1072-1079
    • Yang, L.-Y.1    Li, L.2    Keating, M.J.3    Plunkett, W.4
  • 23
    • 0029859821 scopus 로고    scopus 로고
    • Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes
    • Sandoval, A., Consoli, U., and Plunkett, W. Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes. Clin. Cancer Res., 2: 1731-1742, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1731-1742
    • Sandoval, A.1    Consoli, U.2    Plunkett, W.3
  • 24
    • 0030983004 scopus 로고    scopus 로고
    • Fludarabine triphosphate inhibits nucleotide excision repair of cisplatin-induced DNA adducts in vitro
    • Li, L., Liu, X-m., Glassman, A. B., Keating, M. J., Stros, M., Plunkett, W., and Yang, L-Y. Fludarabine triphosphate inhibits nucleotide excision repair of cisplatin-induced DNA adducts in vitro. Cancer Res., 57: 1487-1494, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1487-1494
    • Li, L.1    Liu, X.-M.2    Glassman, A.B.3    Keating, M.J.4    Stros, M.5    Plunkett, W.6    Yang, L.-Y.7
  • 25
    • 0030921076 scopus 로고    scopus 로고
    • Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells
    • Iwasaki, H., Huang, P., and Plunkett, W. Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells. Blood, 90: 270-278, 1997.
    • (1997) Blood , vol.90 , pp. 270-278
    • Iwasaki, H.1    Huang, P.2    Plunkett, W.3
  • 26
    • 0030775770 scopus 로고    scopus 로고
    • Fludarabinemediated inhibition of cisplatin-induced DNA lesions in chronic myelogenous leukemia-blast crisis K562 cells: Induction of synergistic cytotoxicity independent of reversal of apoptosis resistance
    • Li, L., Keating, M. J., Plunkett, W., and Yang, L-Y. Fludarabinemediated inhibition of cisplatin-induced DNA lesions in chronic myelogenous leukemia-blast crisis K562 cells: induction of synergistic cytotoxicity independent of reversal of apoptosis resistance. Mol. Pharmacol., 52: 798-806, 1997.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 798-806
    • Li, L.1    Keating, M.J.2    Plunkett, W.3    Yang, L.-Y.4
  • 27
    • 0025914099 scopus 로고
    • Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells
    • Johnes, J., Zhen, W., Reed, E., Parker, R. J., Sancar, A., and Bohr, V. A. Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells. J. Biol. Chem., 266: 7101-7107 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7101-7107
    • Johnes, J.1    Zhen, W.2    Reed, E.3    Parker, R.J.4    Sancar, A.5    Bohr, V.A.6
  • 28
    • 0029001182 scopus 로고
    • Excision repair in mammalian cells
    • Sancar, A Excision repair in mammalian cells. J. Biol. Chem., 270: 15915-15918, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15915-15918
    • Sancar, A.1
  • 29
    • 0030580940 scopus 로고    scopus 로고
    • Evidence that mammalian cells possess homologous recombinational repair pathways
    • Thompson, L. H. Evidence that mammalian cells possess homologous recombinational repair pathways. Mutat. Res., 363: 77-88, 1996.
    • (1996) Mutat. Res. , vol.363 , pp. 77-88
    • Thompson, L.H.1
  • 30
    • 0028326742 scopus 로고
    • Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines
    • Johnson, S. W., Perez, R. P., Godwin, A. K., Yeung, A. T., Handel, L. M., Ozols, R. F., and Hamilton, T. C. Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines. Biochem. Pharmacol., 47: 689-697, 1994.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 689-697
    • Johnson, S.W.1    Perez, R.P.2    Godwin, A.K.3    Yeung, A.T.4    Handel, L.M.5    Ozols, R.F.6    Hamilton, T.C.7
  • 31
    • 0027457743 scopus 로고
    • DNA excision-repair synthesis is enhanced in a murine leukemia L1210 cell line resistant to cisplatin
    • Calsou, P., Barret, J-M., Cros, S., and Salles, B. DNA excision-repair synthesis is enhanced in a murine leukemia L1210 cell line resistant to cisplatin. Eur. J. Biochem., 211: 403-409, 1993.
    • (1993) Eur. J. Biochem. , vol.211 , pp. 403-409
    • Calsou, P.1    Barret, J.-M.2    Cros, S.3    Salles, B.4
  • 35
    • 0030855734 scopus 로고    scopus 로고
    • Loss of DNA mismatch repair due to knockout of MSH2 or PMS2 results in resistance to cisplatin and carboplatin
    • Fink, D., Nebel S., Aebi, S., Nehme, A., and Howell, S. B. Loss of DNA mismatch repair due to knockout of MSH2 or PMS2 results in resistance to cisplatin and carboplatin. Int. J. Oncol., 11: 539-542, 1997.
    • (1997) Int. J. Oncol. , vol.11 , pp. 539-542
    • Fink, D.1    Nebel, S.2    Aebi, S.3    Nehme, A.4    Howell, S.B.5
  • 36
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong, J. G., Costanzo, A., Yang, H-Q., Melino, G., Kaelin, W. G., Levreri, M., and Wang, J. Y. J. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature (Lond.), 399: 806-809, 1999.
    • (1999) Nature (Lond.) , vol.399 , pp. 806-809
    • Gong, J.G.1    Costanzo, A.2    Yang, H.-Q.3    Melino, G.4    Kaelin, W.G.5    Levreri, M.6    Wang, J.Y.J.7
  • 37
    • 0032529467 scopus 로고    scopus 로고
    • The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts
    • Vaisman, A., Varchenko, M., Umar, A., Kunkel, T. A., Risinger, J. I., Barrett, J. C., Hamilton, T. C., and Chaney, S. G. The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts. Cancer Res., 58: 6443-6447, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 6443-6447
    • Vaisman, A.1    Varchenko, M.2    Umar, A.3    Kunkel, T.A.4    Risinger, J.I.5    Barrett, J.C.6    Hamilton, T.C.7    Chaney, S.G.8
  • 38
    • 0029095693 scopus 로고
    • Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease
    • Park, C-H., Bessho, T., Matsunaga, T., and Sancar, A. Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease. J. Biol. Chem., 29: 22657-22660, 1995.
    • (1995) J. Biol. Chem. , vol.29 , pp. 22657-22660
    • Park, C.-H.1    Bessho, T.2    Matsunaga, T.3    Sancar, A.4
  • 39
    • 0022534749 scopus 로고
    • Molecular characterization of the human excision repair gene ERCC-1: CDNA cloning and amino acid homology with the yeast DNA repair gene RAD10
    • van Duin, M., de Wit, J., Odijk, H., Westerveld, A., Yasui, A., Koken, M. H. M., Hoeijmakers, J. H. J., and Bootsma, D. Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10. Cell, 44: 913-923, 1986.
    • (1986) Cell , vol.44 , pp. 913-923
    • Van Duin, M.1    De Wit, J.2    Odijk, H.3    Westerveld, A.4    Yasui, A.5    Koken, M.H.M.6    Hoeijmakers, J.H.J.7    Bootsma, D.8
  • 40
    • 0027372625 scopus 로고
    • Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3
    • Lond.
    • Lee, K. B., Parker, R. J., Bohr, V., Cornelison, T., and Reed, E. Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3. Carcinogenesis (Lond.), 14: 2177-2180, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 2177-2180
    • Lee, K.B.1    Parker, R.J.2    Bohr, V.3    Cornelison, T.4    Reed, E.5
  • 41
    • 0027473181 scopus 로고
    • Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: A comprehensive survey of genetic and biochemical characteristics
    • Collins, A. R. Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res., 29: 99-118, 1993.
    • (1993) Mutat. Res. , vol.29 , pp. 99-118
    • Collins, A.R.1
  • 42
    • 0031905245 scopus 로고    scopus 로고
    • Gemcitabine induces programmed cell death and activates protein kinase C in BG-1 human ovarian cancer cells
    • Cartee, L., and Kucera, G. L. Gemcitabine induces programmed cell death and activates protein kinase C in BG-1 human ovarian cancer cells. Cancer (Phila.) Chemother. Pharmacol., 41: 403-412, 1998.
    • (1998) Cancer (Phila.) Chemother. Pharmacol. , vol.41 , pp. 403-412
    • Cartee, L.1    Kucera, G.L.2
  • 43
    • 0029866780 scopus 로고    scopus 로고
    • Reversible protein phosphorylation modulates nucleotide excision repair of damaged DNA by human extracts
    • Ariza, R. R., Keyse, S. M., Moggs, J. G., and Wood, R. D. Reversible protein phosphorylation modulates nucleotide excision repair of damaged DNA by human extracts. Nucleic Acids Res., 24: 433-440, 1996.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 433-440
    • Ariza, R.R.1    Keyse, S.M.2    Moggs, J.G.3    Wood, R.D.4
  • 44
    • 0027534919 scopus 로고
    • Distinct P-glycoprotein expression in two subclones simultaneously selected from a human colon carcinoma cell line by cis-diamminedichloroplatinum(II)
    • Yang, L-Y., Trujillo, J. M., Siciliano, M. J., Kido, Y., Siddick, Z., and Su, Y-Z. Distinct P-glycoprotein expression in two subclones simultaneously selected from a human colon carcinoma cell line by cis-diamminedichloroplatinum(II). Int. J. Cancer, 53: 478-485, 1993.
    • (1993) Int. J. Cancer , vol.53 , pp. 478-485
    • Yang, L.-Y.1    Trujillo, J.M.2    Siciliano, M.J.3    Kido, Y.4    Siddick, Z.5    Su, Y.-Z.6
  • 45
    • 0028301255 scopus 로고
    • Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
    • Umar, A., Boyer, J. C., Thomas, D. C., Nguyen, D. C., Risinger, J. I., Boyd, J., Ionov, Y., Perucho, M., and Kunkel, T. A. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J. Biol. Chem., 269: 14367-14370, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14367-14370
    • Umar, A.1    Boyer, J.C.2    Thomas, D.C.3    Nguyen, D.C.4    Risinger, J.I.5    Boyd, J.6    Ionov, Y.7    Perucho, M.8    Kunkel, T.A.9
  • 46
    • 0024467344 scopus 로고
    • Repair synthesis by human cell extracts in DNA damaged by cis- And trans-diamminedichloroplatinum (II)
    • Hansson, J., and Wood, R. D. Repair synthesis by human cell extracts in DNA damaged by cis- and trans-diamminedichloroplatinum (II). Nucleic Acids Res., 20: 8073-8091, 1989.
    • (1989) Nucleic Acids Res. , vol.20 , pp. 8073-8091
    • Hansson, J.1    Wood, R.D.2
  • 47
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationship: The combined effects of multiple drugs or enzyme inhibitors
    • Chou, T-C., and Talay, P. Quantitative analysis of dose-effect relationship: The combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme. Regul., 22: 27-55, 1984.
    • (1984) Adv. Enzyme. Regul. , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talay, P.2
  • 49
    • 0033426724 scopus 로고    scopus 로고
    • Use of novel plasmid constructs to demonstrate fludarabine triphosphate inhibition of nucleotide excision repair of a site-specific 1,2-d(GpG) intrastrand cisplatin adduct
    • Li, M.-J., and Yang, L.-Y. Use of novel plasmid constructs to demonstrate fludarabine triphosphate inhibition of nucleotide excision repair of a site-specific 1,2-d(GpG) intrastrand cisplatin adduct. Int. J. Oncol., 15: 1177-1183, 1999.
    • (1999) Int. J. Oncol. , vol.15 , pp. 1177-1183
    • Li, M.-J.1    Yang, L.-Y.2
  • 50
    • 0030933164 scopus 로고    scopus 로고
    • Overexpression and activation of the insulin receptor enhances expression of ERCC-1 messenger ribonucleic acid in cultured cells
    • Perfetti, R., Lee-Kwon, W., Montrose-Rafizadeh, C., and Bernier, M. Overexpression and activation of the insulin receptor enhances expression of ERCC-1 messenger ribonucleic acid in cultured cells. The Endocrine Society, 138: 1829-1835, 1997.
    • (1997) The Endocrine Society , vol.138 , pp. 1829-1835
    • Perfetti, R.1    Lee-Kwon, W.2    Montrose-Rafizadeh, C.3    Bernier, M.4
  • 52
    • 0028304833 scopus 로고
    • Formation of a ternary complex by human XPA, ERCC1, and ERCC4 (XPF) excision repair proteins
    • Park, C-H., and Sancar, A. Formation of a ternary complex by human XPA, ERCC1, and ERCC4 (XPF) excision repair proteins. Proc. Natl. Acad. Sci. USA, 91: 5017-5021, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5017-5021
    • Park, C.-H.1    Sancar, A.2
  • 53
    • 0031883776 scopus 로고    scopus 로고
    • 1 -dependent mice show increased genome instability and a reduced frequency of S-phase-dependent illegitimate chromosome exchange but a normal frequency of homologous recombination
    • 1 -dependent mice show increased genome instability and a reduced frequency of S-phase-dependent illegitimate chromosome exchange but a normal frequency of homologous recombination. J. Cell Sci., 111: 395-404, 1998.
    • (1998) J. Cell Sci. , vol.111 , pp. 395-404
    • Melton, D.W.1    Ketchen, A.M.2    Nunez, F.3    Bonatti-Abbondandolo, S.4    Abbondandolo, A.5    Squires, S.6    Johnson, R.T.7
  • 54
    • 0032814145 scopus 로고    scopus 로고
    • Interstrand cross-links induce DNA synthesis in damaged and undamaged plasmids in mammalian cell extracts
    • Li, L., Peterson, C. A., Lu, X., Wei, P., and Legerski, R. J. Interstrand cross-links induce DNA synthesis in damaged and undamaged plasmids in mammalian cell extracts. Mol. Cell. Biol., 19: 5619-5630, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5619-5630
    • Li, L.1    Peterson, C.A.2    Lu, X.3    Wei, P.4    Legerski, R.J.5
  • 55
    • 0026569275 scopus 로고
    • Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin
    • Washington DC
    • Pil, P. M., and Lippard, S. J. Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science (Washington DC), 256: 234-237, 1992.
    • (1992) Science , vol.256 , pp. 234-237
    • Pil, P.M.1    Lippard, S.J.2
  • 56
    • 0028117527 scopus 로고
    • HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease
    • Huang, J-C., Zambie, D. B., Reardon, J. T., Lippard, S. J., and Sancar, A. HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease. Proc. Natl. Acad. Sci. USA, 91: 10394-10398, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10394-10398
    • Huang, J.-C.1    Zambie, D.B.2    Reardon, J.T.3    Lippard, S.J.4    Sancar, A.5
  • 57
    • 0031458832 scopus 로고    scopus 로고
    • The major chromatin protein histone H1 binds preferentially to cisplatinum-damaged DNA
    • Yaneva, J., Leuba, S. H., van Holde, K., and Zlatanova, J. The major chromatin protein histone H1 binds preferentially to cisplatinum-damaged DNA. Proc. Natl. Acad. Sci. USA, 94: 13448-13451, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13448-13451
    • Yaneva, J.1    Leuba, S.H.2    Van Holde, K.3    Zlatanova, J.4
  • 58
    • 0025089191 scopus 로고
    • Pharmacologically directed design of the dose rate and schedule of 2′,2′-difluorodeoxycytidine (gemcitabine) administration in leukemia
    • Grunewald, R., Kantarjian, H., Keating, M. J., Abbruzzese, J., Tarassoff, P., and Plunkett, W. Pharmacologically directed design of the dose rate and schedule of 2′,2′-difluorodeoxycytidine (gemcitabine) administration in leukemia. Cancer Res., 50: 6823-6826, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6823-6826
    • Grunewald, R.1    Kantarjian, H.2    Keating, M.J.3    Abbruzzese, J.4    Tarassoff, P.5    Plunkett, W.6
  • 60
    • 0026571795 scopus 로고
    • Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation
    • Heinemann, V., Xu, Y-Z., Chubb, S., Sen, A., Hertel, L. W., Grindey, G. B., and Plunkett, W. Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation. Cancer Res., 52: 533-539, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 533-539
    • Heinemann, V.1    Xu, Y.-Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6    Plunkett, W.7
  • 61
    • 0029782426 scopus 로고    scopus 로고
    • Excision of 2′,2′-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA
    • Gandhi, V., Legha, J., Chen, F., Hertel, L. W., and Plunkett, W. Excision of 2′,2′-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA. Cancer Res., 56: 4453-4459, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4453-4459
    • Gandhi, V.1    Legha, J.2    Chen, F.3    Hertel, L.W.4    Plunkett, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.