-
1
-
-
0025838832
-
Treatment with interleukin-3 plus granulocyte-macrophage colony-stimulating factors improves the selectivity of Ara-C in vitro against acute myeloid leukemia blasts
-
Bhalla K, Holladay C, Arlin Z, Grant S, Ibrado AM, Jasiok M (1991) Treatment with interleukin-3 plus granulocyte-macrophage colony-stimulating factors improves the selectivity of Ara-C in vitro against acute myeloid leukemia blasts. Blood 78: 2674
-
(1991)
Blood
, vol.78
, pp. 2674
-
-
Bhalla, K.1
Holladay, C.2
Arlin, Z.3
Grant, S.4
Ibrado, A.M.5
Jasiok, M.6
-
2
-
-
0026476483
-
Granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) enhances high-dose Ara-C-induced programmed cell death or apoptosis in human myeloid leukemia cells
-
Bhalla K, Tang C, Ibrado AM, Grant S, Tourkina E, Holladay C, Hughes M, Mahoney ME, Huang Y (1992) Granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) enhances high-dose Ara-C-induced programmed cell death or apoptosis in human myeloid leukemia cells. Blood 80: 2883
-
(1992)
Blood
, vol.80
, pp. 2883
-
-
Bhalla, K.1
Tang, C.2
Ibrado, A.M.3
Grant, S.4
Tourkina, E.5
Holladay, C.6
Hughes, M.7
Mahoney, M.E.8
Huang, Y.9
-
3
-
-
0027538162
-
Effect of hemopoietic growth factors G-CSF and pIXY 321 on the activity of high dose Ara-C in human myeloid leukemia cells
-
Bhalla K, Tourkina E, Huang Y, Tang C, Mahoney ME, Ibrado AM (1993) Effect of hemopoietic growth factors G-CSF and pIXY 321 on the activity of high dose Ara-C in human myeloid leukemia cells. Leuk Lymphoma 10 [Suppl]: 123
-
(1993)
Leuk Lymphoma
, vol.10
, Issue.SUPPL.
, pp. 123
-
-
Bhalla, K.1
Tourkina, E.2
Huang, Y.3
Tang, C.4
Mahoney, M.E.5
Ibrado, A.M.6
-
4
-
-
15644374247
-
Comparison of cytosine arabinoside and 2′,2′-difluorodeoxycytidine (Gemcitabine) on the induction of apoptotic cell death in HL-60 myeloid leukemic cells
-
Bouffard DY, Momparler RL (1994) Comparison of cytosine arabinoside and 2′,2′-difluorodeoxycytidine (Gemcitabine) on the induction of apoptotic cell death in HL-60 myeloid leukemic cells. Proc Am Assoc Cancer Res 35: 317
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 317
-
-
Bouffard, D.Y.1
Momparler, R.L.2
-
5
-
-
0027263596
-
The influence of the schedule and the dose of gemcitabine on the anti-tumour efficacy in experimental human cancer
-
Boven E, Schipper H, Erkelens CA, Hatty SA, Pinedo HM (1993) The influence of the schedule and the dose of gemcitabine on the anti-tumour efficacy in experimental human cancer. Br J Cancer 68: 52
-
(1993)
Br J Cancer
, vol.68
, pp. 52
-
-
Boven, E.1
Schipper, H.2
Erkelens, C.A.3
Hatty, S.A.4
Pinedo, H.M.5
-
6
-
-
0029053742
-
2-Phosphorylation of the MARCKS family of protein kinase C substrates in human B chronic lymphocytic leukemia cells
-
Carballo E, Colomer D, Vives Corrons JL, Blackshear PJ, Gil J (1995) 2-Phosphorylation of the MARCKS family of protein kinase C substrates in human B chronic lymphocytic leukemia cells. Leukemia 9: 834
-
(1995)
Leukemia
, vol.9
, pp. 834
-
-
Carballo, E.1
Colomer, D.2
Vives Corrons, J.L.3
Blackshear, P.J.4
Gil, J.5
-
7
-
-
0023727698
-
Effects of epidermal growth factor and phorbol 12-myristate 13-acetate on protein phosphorylation in mouse embryo palate mesenchyme cells, in vitro
-
Chepenik KP, Grunwald GB (1988) Effects of epidermal growth factor and phorbol 12-myristate 13-acetate on protein phosphorylation in mouse embryo palate mesenchyme cells, in vitro. J Craniofacial Genet Dev Biol 8: 147
-
(1988)
J Craniofacial Genet Dev Biol
, vol.8
, pp. 147
-
-
Chepenik, K.P.1
Grunwald, G.B.2
-
8
-
-
0029050456
-
Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo
-
Columbano A (1995) Cell death: current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J Cell Biochem 58: 181
-
(1995)
J Cell Biochem
, vol.58
, pp. 181
-
-
Columbano, A.1
-
9
-
-
0025945651
-
Enhanced hematopoietic activity of a human granulocyte macrophage colony-stimulating factor-interleukin 3 fusion protein
-
Curtis BM, Williams DE, Broxmeyer HE, Dunn J, Farrah T, Jeffrey E, Clevenger W, DeRoos P, Martin U, Friend D, Craig V, Gayle R, Price V, Cosman D, March CJ, Park LS (1991) Enhanced hematopoietic activity of a human granulocyte macrophage colony-stimulating factor-interleukin 3 fusion protein. Proc Natl Acad Sci USA 88: 5809
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5809
-
-
Curtis, B.M.1
Williams, D.E.2
Broxmeyer, H.E.3
Dunn, J.4
Farrah, T.5
Jeffrey, E.6
Clevenger, W.7
Deroos, P.8
Martin, U.9
Friend, D.10
Craig, V.11
Gayle, R.12
Price, V.13
Cosman, D.14
March, C.J.15
Park, L.S.16
-
10
-
-
13344259987
-
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells
-
Emoto Y, Manome Y, Meinhardt G, Kisaki H, Kharbanda S, Robertson M, Ghayur T, Wong WW, Kamen R, Weichselbaum R, et al. (1995) Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J 14: 6148
-
(1995)
EMBO J
, vol.14
, pp. 6148
-
-
Emoto, Y.1
Manome, Y.2
Meinhardt, G.3
Kisaki, H.4
Kharbanda, S.5
Robertson, M.6
Ghayur, T.7
Wong, W.W.8
Kamen, R.9
Weichselbaum, R.10
-
11
-
-
0030023982
-
Activation of protein kinase C delta in human myeloid leukemia cells treated with 1-β-D-abinofuranosyl-cytosine
-
Emoto Y, Kisaki H, Manome Y, Kharbanda S, Kufe D (1996) Activation of protein kinase C delta in human myeloid leukemia cells treated with 1-β-D-abinofuranosyl-cytosine. Blood 87: 1990
-
(1996)
Blood
, vol.87
, pp. 1990
-
-
Emoto, Y.1
Kisaki, H.2
Manome, Y.3
Kharbanda, S.4
Kufe, D.5
-
12
-
-
0024489926
-
Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors
-
Geisinger KR, Kute TE, Pettenati MJ, Welander CE, Dennard Y, Collins LA, Berens ME (1989) Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors. Cancer 63: 280
-
(1989)
Cancer
, vol.63
, pp. 280
-
-
Geisinger, K.R.1
Kute, T.E.2
Pettenati, M.J.3
Welander, C.E.4
Dennard, Y.5
Collins, L.A.6
Berens, M.E.7
-
13
-
-
12644268232
-
Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
-
Ghayur T, Hugunin M, Talanian RV, Ratnofsky S, Quinlan C, Emoto Y, Pandey P, Datta R, Huang YY, Kharbanda S, Allen H, Kamen R, Wong W, Kufe D (1996) Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis. J Exp Med 184: 2399
-
(1996)
J Exp Med
, vol.184
, pp. 2399
-
-
Ghayur, T.1
Hugunin, M.2
Talanian, R.V.3
Ratnofsky, S.4
Quinlan, C.5
Emoto, Y.6
Pandey, P.7
Datta, R.8
Huang, Y.Y.9
Kharbanda, S.10
Allen, H.11
Kamen, R.12
Wong, W.13
Kufe, D.14
-
14
-
-
15644367410
-
Regulation of 1-β-D-arabinofuranosylcytosine-induced apoptosis in myeloid leukemia cells by pharmacologic and physiologic activators of PKC: Evidence that potentiation of this process is related to enzyme down-regulation
-
Grant S, Turner A, Jarvis D (1994) Regulation of 1-β-D-arabinofuranosylcytosine-induced apoptosis in myeloid leukemia cells by pharmacologic and physiologic activators of PKC: evidence that potentiation of this process is related to enzyme down-regulation. Proc Am Assoc Cancer Res 35: 312
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 312
-
-
Grant, S.1
Turner, A.2
Jarvis, D.3
-
15
-
-
0029902591
-
Clinical, toxicological, and pharmacological aspects of gemcitabine
-
Guchelaar H, Richel DJ, Knapen A van (1996) Clinical, toxicological, and pharmacological aspects of gemcitabine. Cancer Treat Rev 22: 15
-
(1996)
Cancer Treat Rev
, vol.22
, pp. 15
-
-
Guchelaar, H.1
Richel, D.J.2
Van Knapen, A.3
-
16
-
-
0025961302
-
Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-β-D-arabinofuranosylcytosine
-
Gunji H, Kharbanda S, Kufe D (1991) Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-β-D-arabinofuranosylcytosine. Cancer Res 51: 741
-
(1991)
Cancer Res
, vol.51
, pp. 741
-
-
Gunji, H.1
Kharbanda, S.2
Kufe, D.3
-
17
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
-
Heinemann V, Hertel LW, Grindey GB, Plunkett W (1988) Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res 48: 4024
-
(1988)
Cancer Res
, vol.48
, pp. 4024
-
-
Heinemann, V.1
Hertel, L.W.2
Grindey, G.B.3
Plunkett, W.4
-
18
-
-
0025049372
-
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine
-
Heinemann V, Xu YZ, Chubb S, Sen A, Hertel LW, Grindey GB, Plunkett W (1990) Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine. Mol Pharmacol 38: 567
-
(1990)
Mol Pharmacol
, vol.38
, pp. 567
-
-
Heinemann, V.1
Xu, Y.Z.2
Chubb, S.3
Sen, A.4
Hertel, L.W.5
Grindey, G.B.6
Plunkett, W.7
-
19
-
-
0026697873
-
Relationship between the major protein kinase C substrates acidic 80-kDa protein-kinase-C substrate (80 K) and myristoylated alanine-rich C-kinase substrate (MARCKS). Members of a gene family or equivalent genes in different species
-
Herget T, Brooks SF, Broad S, Rozengurt E (1992) Relationship between the major protein kinase C substrates acidic 80-kDa protein-kinase-C substrate (80 K) and myristoylated alanine-rich C-kinase substrate (MARCKS). Members of a gene family or equivalent genes in different species. Eur J Biochem 209: 7
-
(1992)
Eur J Biochem
, vol.209
, pp. 7
-
-
Herget, T.1
Brooks, S.F.2
Broad, S.3
Rozengurt, E.4
-
20
-
-
0028803974
-
The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C
-
Herget T, Oehrlein SA, Pappin DJ, Rozengurt E, Parker PJ (1995) The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C. Eur J Biochem 233: 448
-
(1995)
Eur J Biochem
, vol.233
, pp. 448
-
-
Herget, T.1
Oehrlein, S.A.2
Pappin, D.J.3
Rozengurt, E.4
Parker, P.J.5
-
21
-
-
0026533427
-
Granulocyte-macrophage colony-stimulating factor and interleukin-3 enhance the incorporation of cytosine arabinoside into the DNA of leukemic blasts and the cytotoxic effect on clonogenic cells from patients with acute myeloid leukemia
-
Hiddemann W, Kiehl M, Zuhlsdorf M, Busemann C, Schleyer E, Wormann B, Buchner T (1992) Granulocyte-macrophage colony-stimulating factor and interleukin-3 enhance the incorporation of cytosine arabinoside into the DNA of leukemic blasts and the cytotoxic effect on clonogenic cells from patients with acute myeloid leukemia. Semin Oncol 19: 31
-
(1992)
Semin Oncol
, vol.19
, pp. 31
-
-
Hiddemann, W.1
Kiehl, M.2
Zuhlsdorf, M.3
Busemann, C.4
Schleyer, E.5
Wormann, B.6
Buchner, T.7
-
22
-
-
0029060757
-
Fludarabine and gemcitabine-induced apoptosis: Incorporation of analogs into DNA is a critical event
-
Huang P, Plunkett W (1995) Fludarabine and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol 36: 181
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 181
-
-
Huang, P.1
Plunkett, W.2
-
23
-
-
0028783440
-
Induction of apoptosis by gemcitabine
-
Huang P, Plunkett W (1995) Induction of apoptosis by gemcitabine. Semin Oncol 22: 19
-
(1995)
Semin Oncol
, vol.22
, pp. 19
-
-
Huang, P.1
Plunkett, W.2
-
24
-
-
0028181584
-
Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[β-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells
-
Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S (1994) Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[β-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. Biochem Pharmacol 47: 839
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 839
-
-
Jarvis, W.D.1
Povirk, L.F.2
Turner, A.J.3
Traylor, R.S.4
Gewirtz, D.A.5
Pettit, G.R.6
Grant, S.7
-
25
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239
-
(1972)
Br J Cancer
, vol.26
, pp. 239
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
27
-
-
0025867205
-
Regulation of c-jun gene expression in HL-60 leukemia cells by 1-β-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism
-
Kharbanda S, Datta R, Kufe D (1991) Regulation of c-jun gene expression in HL-60 leukemia cells by 1-β-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism. Biochemistry 30: 7947
-
(1991)
Biochemistry
, vol.30
, pp. 7947
-
-
Kharbanda, S.1
Datta, R.2
Kufe, D.3
-
28
-
-
0026638006
-
1-β-D-Arabinofuranosylcytosine-diphosphate-choline is formed by the reversal of choline-phosphotransferase and not via cytidylyltransferase
-
Kucera GL, Capizzi RL (1992) 1-β-D-Arabinofuranosylcytosine-diphosphate-choline is formed by the reversal of choline-phosphotransferase and not via cytidylyltransferase. Cancer Res 52: 3886
-
(1992)
Cancer Res
, vol.52
, pp. 3886
-
-
Kucera, G.L.1
Capizzi, R.L.2
-
29
-
-
0027399764
-
Clinical and preclinical activity of 2′,2′-difluorodeoxycytidine (gemcitabine)
-
Lund B, Kristjansen PEG, Hansen HH (1993) Clinical and preclinical activity of 2′,2′-difluorodeoxycytidine (gemcitabine). Cancer Treat Rev 19: 45
-
(1993)
Cancer Treat Rev
, vol.19
, pp. 45
-
-
Lund, B.1
Kristjansen, P.E.G.2
Hansen, H.H.3
-
30
-
-
0029055676
-
Ceramide: A stress signal and mediator of growth suppression and apoptosis
-
Obeid LM, Hannun YA (1995) Ceramide: a stress signal and mediator of growth suppression and apoptosis. J Cell Biochem 58: 191
-
(1995)
J Cell Biochem
, vol.58
, pp. 191
-
-
Obeid, L.M.1
Hannun, Y.A.2
-
31
-
-
0027217084
-
Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
-
Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR, Sikorska M (1993) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12: 3679
-
(1993)
EMBO J
, vol.12
, pp. 3679
-
-
Oberhammer, F.1
Wilson, J.W.2
Dive, C.3
Morris, I.D.4
Hickman, J.A.5
Wakeling, A.E.6
Walker, P.R.7
Sikorska, M.8
-
32
-
-
0028263376
-
Cisplatin induces apoptosis in a human ovarian carcinoma cell line without concomitant internucleosomal degradation of DNA
-
Ormerod MG, O'Neill CF, Robertson D, Harrap KR (1994) Cisplatin induces apoptosis in a human ovarian carcinoma cell line without concomitant internucleosomal degradation of DNA. Exp Cell Res 211: 231
-
(1994)
Exp Cell Res
, vol.211
, pp. 231
-
-
Ormerod, M.G.1
O'Neill, C.F.2
Robertson, D.3
Harrap, K.R.4
-
33
-
-
0028167771
-
1-beta-D-arabinofuranosylcytosine-, mitoxantrone-, and paclitaxel-induced apoptosis in HL-60 cells: Improved method for detection of internucleosomal DNA fragmentation
-
Ray S, Ponnathpur V, Huang Y, Tang C, Mahoney ME, Ibrado AM, Bullock G, Bhalla K (1994) 1-beta-D-arabinofuranosylcytosine-, mitoxantrone-, and paclitaxel-induced apoptosis in HL-60 cells: improved method for detection of internucleosomal DNA fragmentation. Cancer Chemother Pharmacol 34: 365
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 365
-
-
Ray, S.1
Ponnathpur, V.2
Huang, Y.3
Tang, C.4
Mahoney, M.E.5
Ibrado, A.M.6
Bullock, G.7
Bhalla, K.8
-
35
-
-
0027429568
-
Effect of a template-located 2′,2′,-difluorodeoxycytidine on the kinetics and fidelity of base insertion by klenow (3′-5′ exonuclease) fragment
-
Schy WE, Hertel LW, Kroin KS, Bloom LB, Goodman MF, Richardson FC (1993) Effect of a template-located 2′,2′,-difluorodeoxycytidine on the kinetics and fidelity of base insertion by klenow (3′-5′ exonuclease) fragment. Cancer Res 53: 4582
-
(1993)
Cancer Res
, vol.53
, pp. 4582
-
-
Schy, W.E.1
Hertel, L.W.2
Kroin, K.S.3
Bloom, L.B.4
Goodman, M.F.5
Richardson, F.C.6
-
36
-
-
0028059964
-
Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators
-
Stewart BW (1994) Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators. J Nat Cancer Inst 86: 1286
-
(1994)
J Nat Cancer Inst
, vol.86
, pp. 1286
-
-
Stewart, B.W.1
-
37
-
-
0028903616
-
Phorbol ester treatment of U937 cells with altered protein kinase C content and distribution induces cell death rather than differentiation
-
Vente J de, Kiley S, Garris T, Bryant W, Hooker J, Posekany K, Parker P, Cook P, Fletcher D, Ways DK (1995) Phorbol ester treatment of U937 cells with altered protein kinase C content and distribution induces cell death rather than differentiation. Cell Growth Differ 6: 371
-
(1995)
Cell Growth Differ
, vol.6
, pp. 371
-
-
De Vente, J.1
Kiley, S.2
Garris, T.3
Bryant, W.4
Hooker, J.5
Posekany, K.6
Parker, P.7
Cook, P.8
Fletcher, D.9
Ways, D.K.10
-
38
-
-
0028805717
-
Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death
-
Vente JE de, Kukoly CA, Bryant WO, Posekany KJ, Chen J, Fletcher DJ, Parker PJ, Pettit GJ, Lozano G, Cook PP, et al. (1995) Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death. J Clin Invest 96: 1874
-
(1995)
J Clin Invest
, vol.96
, pp. 1874
-
-
De Vente, J.E.1
Kukoly, C.A.2
Bryant, W.O.3
Posekany, K.J.4
Chen, J.5
Fletcher, D.J.6
Parker, P.J.7
Pettit, G.J.8
Lozano, G.9
Cook, P.P.10
-
39
-
-
0027943488
-
Deoxycytidine kinase is phosphorylated in vitro by protein kinase C alpha
-
Wang LM, Kucera GL (1994) Deoxycytidine kinase is phosphorylated in vitro by protein kinase C alpha. Biochim Biophys Acta 1224: 161
-
(1994)
Biochim Biophys Acta
, vol.1224
, pp. 161
-
-
Wang, L.M.1
Kucera, G.L.2
-
40
-
-
0025062503
-
A synthetic peptide substrate for selective assay of protein kinase C
-
Yasuda I, Kishimoto I, Tanaka S, Tominga M, Sakura A, Nishizuka Y (1990) A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun 166: 1220
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 1220
-
-
Yasuda, I.1
Kishimoto, I.2
Tanaka, S.3
Tominga, M.4
Sakura, A.5
Nishizuka, Y.6
|