-
1
-
-
0023935362
-
Synthesis of 2′-deoxy-2′,2′-difluoro-D-ribose and 2-Deoxy-2,2-difluoro-D-ribofuranosyl nucleosides
-
Hertel L.W., Kroin J.S., Misner J.W., Tustin J.M. Synthesis of 2′-deoxy-2′,2′-difluoro-D-ribose and 2-Deoxy-2,2-difluoro-D-ribofuranosyl nucleosides. J. Org. Chem. 53:1988;2406-2409.
-
(1988)
J. Org. Chem.
, vol.53
, pp. 2406-2409
-
-
Hertel, L.W.1
Kroin, J.S.2
Misner, J.W.3
Tustin, J.M.4
-
2
-
-
0030915362
-
Gemcitabine: Future prospects of single-agents and combination studies
-
Van Moorsel C.J.A., Peters G.J., Pinedo H.M. Gemcitabine: future prospects of single-agents and combination studies. The Oncologist. 2:1997;127-134.
-
(1997)
The Oncologist
, vol.2
, pp. 127-134
-
-
Van Moorsel, C.J.A.1
Peters, G.J.2
Pinedo, H.M.3
-
3
-
-
0026324313
-
Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
-
Huang P., Chubb S., Hertel L.W., Grindey G.B., Plunkett W. Action of 2′,2′-difluorodeoxycytidine on DNA synthesis. Cancer Res. 51:1991;6110-6117.
-
(1991)
Cancer Res.
, vol.51
, pp. 6110-6117
-
-
Huang, P.1
Chubb, S.2
Hertel, L.W.3
Grindey, G.B.4
Plunkett, W.5
-
4
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
-
Heinemann V., Hertel L.W., Grindey G.B., Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res. 48:1988;4024-4031.
-
(1988)
Cancer Res.
, vol.48
, pp. 4024-4031
-
-
Heinemann, V.1
Hertel, L.W.2
Grindey, G.B.3
Plunkett, W.4
-
5
-
-
0027180521
-
2′,2′-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines
-
Ruiz van Haperen V.W.T., Veerman G., Vermorken J.B., Peters G.J. 2′,2′-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines. Biochem. Pharmacol. 46:1993;762-766.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 762-766
-
-
Ruiz Van Haperen, V.W.T.1
Veerman, G.2
Vermorken, J.B.3
Peters, G.J.4
-
6
-
-
0000125441
-
The coordination chemistry of platinum anticancer drugs and related compounds with DNA
-
Sundquist W.I., Lippard S.J. The coordination chemistry of platinum anticancer drugs and related compounds with DNA. Coord. Chem. Rev. 100:1990;293-322.
-
(1990)
Coord. Chem. Rev.
, vol.100
, pp. 293-322
-
-
Sundquist, W.I.1
Lippard, S.J.2
-
7
-
-
0025363447
-
Correlation between cell killing by cisdiamminedichloroplatinum(II) in six mammalian cell lines and binding of a cisdiamminedichloroplatinum(II)-DNA antiserum
-
Terheggen P.M.A.B., Emondt J.Y., Floot B.G.J., et al. Correlation between cell killing by cisdiamminedichloroplatinum(II) in six mammalian cell lines and binding of a cisdiamminedichloroplatinum(II)-DNA antiserum. Cancer Res. 50:1990;3556-3561.
-
(1990)
Cancer Res.
, vol.50
, pp. 3556-3561
-
-
Terheggen, P.M.A.B.1
Emondt, J.Y.2
Floot, B.G.J.3
-
8
-
-
0025799467
-
Platinum DNA-damage in leucocyte DNA of patients receiving cisplatin and carboplatin chemotherapy, measured by atomic absorption spectrometry
-
Parker R.J., Gill I., Tarone R., et al. Platinum DNA-damage in leucocyte DNA of patients receiving cisplatin and carboplatin chemotherapy, measured by atomic absorption spectrometry. Carcinogenesis. 12:1991;1253-1258.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1253-1258
-
-
Parker, R.J.1
Gill, I.2
Tarone, R.3
-
9
-
-
0030038773
-
Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours
-
Schellens J.H.M., Ma J., Planting A.S.Th., et al. Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours. Br. J. Cancer. 73:1996;1569-1575.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 1569-1575
-
-
Schellens, J.H.M.1
Ma, J.2
Planting, A.s.th.3
-
10
-
-
0029875635
-
Synergistic interaction between cisplatin and gemcitabine in vitro
-
Bergman A.M., Ruiz van Haperen V.W.T., Veerman G., Kuiper C.M., Peters G.J. Synergistic interaction between cisplatin and gemcitabine in vitro. Clin. Cancer Res. 2:1996;521-530.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 521-530
-
-
Bergman, A.M.1
Ruiz Van Haperen, V.W.T.2
Veerman, G.3
Kuiper, C.M.4
Peters, G.J.5
-
11
-
-
0031115156
-
Combination chemotherapy studies with gemcitabine
-
Van Moorsel C.J.A., Veerman G., Bergman A.M., et al. Combination chemotherapy studies with gemcitabine. Semin. Oncol. 24:(Suppl. 7):1997;17-23.
-
(1997)
Semin. Oncol.
, vol.24
, Issue.SUPPL. 7
, pp. 17-23
-
-
Van Moorsel, C.J.A.1
Veerman, G.2
Bergman, A.M.3
-
12
-
-
0032958512
-
Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small cell lung cancer cell lines
-
in press
-
Van Moorsel CJA, Pinedo HM, Veerman G, et al. Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small cell lung cancer cell lines. Br J Cancer 1999, in press.
-
(1999)
Br J Cancer
-
-
Van Moorsel, C.J.A.1
Pinedo, H.M.2
Veerman, G.3
-
13
-
-
0029593648
-
Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts
-
Braakhuis B.J.M., Ruiz van Haperen V.W.T., Welters M.J.P., Peters G.J. Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts. Eur. J. Cancer. 31A:1995;2335-2340.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 2335-2340
-
-
Braakhuis, B.J.M.1
Ruiz Van Haperen, V.W.T.2
Welters, M.J.P.3
Peters, G.J.4
-
14
-
-
0029666336
-
Antitumor activity of prolonged as compared with bolus administration of 2′,2′-difluorodeoxycytidine in vivo against murine colon tumors
-
Veerman G., Ruiz van Haperen V.W.T., Vermorken J.B., et al. Antitumor activity of prolonged as compared with bolus administration of 2′,2′-difluorodeoxycytidine in vivo against murine colon tumors. Cancer Chemother. Pharmacol. 38:1996;335-342.
-
(1996)
Cancer Chemother. Pharmacol.
, vol.38
, pp. 335-342
-
-
Veerman, G.1
Ruiz Van Haperen, V.W.T.2
Vermorken, J.B.3
-
15
-
-
0028784506
-
Interaction between cisplatin and gemcitabine in vitro and in vivo
-
Suppl.
-
Peters G.J., Bergman A.M., Ruiz van Haperen V.W.T., Veerman G., Kuiper C.M., Braakhuis B.J.M. Interaction between cisplatin and gemcitabine in vitro and in vivo. Semin. Oncol. 22:(Suppl.):1995;72-79.
-
(1995)
Semin. Oncol.
, vol.22
, pp. 72-79
-
-
Peters, G.J.1
Bergman, A.M.2
Ruiz Van Haperen, V.W.T.3
Veerman, G.4
Kuiper, C.M.5
Braakhuis, B.J.M.6
-
16
-
-
0000158586
-
Antitumor activity of gemcitabine in combination with cisplatin against the human NSCLC xenograft Calu-6
-
abstract
-
Tanzer LR, Rutherford PG, Self TD, Seymour PD, Theobald KS, Merriman RL. Antitumor activity of gemcitabine in combination with cisplatin against the human NSCLC xenograft Calu-6. Proc AACR 1995, 36, abstract 1761.
-
(1995)
Proc AACR
, vol.36
, pp. 1761
-
-
Tanzer, L.R.1
Rutherford, P.G.2
Self, T.D.3
Seymour, P.D.4
Theobald, K.S.5
Merriman, R.L.6
-
17
-
-
0031032211
-
Weekly gemcitabine with monthly cisplatin: Effective chemotherapy for advanced non-small cell lung cancer
-
Abratt R.P., Bezwoda W.R., Goedhals L., Hacking D.J. Weekly gemcitabine with monthly cisplatin: effective chemotherapy for advanced non-small cell lung cancer. J. Clin. Oncol. 15:1997;744-749.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 744-749
-
-
Abratt, R.P.1
Bezwoda, W.R.2
Goedhals, L.3
Hacking, D.J.4
-
18
-
-
17344384670
-
Cisplatin-gemcitabine combination in advanced non-small cell lung cancer: A phase II study
-
Crino L., Scagliotto G., Marangolo M., et al. Cisplatin-gemcitabine combination in advanced non-small cell lung cancer: a phase II study. J. Clin. Oncol. 15:1997;297-303.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 297-303
-
-
Crino, L.1
Scagliotto, G.2
Marangolo, M.3
-
19
-
-
0344594541
-
Phase I/II study of gemcitabine and cisplatin in non-small cell lung cancer: Preliminary results
-
Steward W.P., Dunlop D.J., Dabouis G., Lacroix H., Talbot D. Phase I/II study of gemcitabine and cisplatin in non-small cell lung cancer: preliminary results. Semin. Oncol. 5:(Suppl. 10):1996;143-147.
-
(1996)
Semin. Oncol.
, vol.5
, Issue.SUPPL. 10
, pp. 143-147
-
-
Steward, W.P.1
Dunlop, D.J.2
Dabouis, G.3
Lacroix, H.4
Talbot, D.5
-
20
-
-
0000360542
-
Influence of gemcitabine (gem) and cisplatin (cp) schedule on response and survival in advanced non-small cell lung cancer (NSCLC)
-
abstract
-
Shepherd FA, Anglin G, Abratt R, et al. Influence of gemcitabine (gem) and cisplatin (cp) schedule on response and survival in advanced non-small cell lung cancer (NSCLC). Proc ASCO 1998, 17, abstract 1817.
-
(1998)
Proc ASCO
, vol.17
, pp. 1817
-
-
Shepherd, F.A.1
Anglin, G.2
Abratt, R.3
-
21
-
-
0031904963
-
Combined cisplatin and gemcitabine for non-small cell lung cancer: Influence of scheduling on toxicity and drug delivery
-
Abratt R.P., Sandler A., Crino L., et al. Combined cisplatin and gemcitabine for non-small cell lung cancer: influence of scheduling on toxicity and drug delivery. Semin. Oncol. 25:(Suppl. 9):1998;35-43.
-
(1998)
Semin. Oncol.
, vol.25
, Issue.SUPPL. 9
, pp. 35-43
-
-
Abratt, R.P.1
Sandler, A.2
Crino, L.3
-
22
-
-
0027942635
-
Protection of normal tissues from the cytotoxic effect of chemotherapy and radiation by amifostine (Ethyol): Preclinical aspects
-
Van der Vijgh W.J.F., Peters G.J. Protection of normal tissues from the cytotoxic effect of chemotherapy and radiation by amifostine (Ethyol): preclinical aspects. Semin. Oncol. 21:1994;2-7.
-
(1994)
Semin. Oncol.
, vol.21
, pp. 2-7
-
-
Van Der Vijgh, W.J.F.1
Peters, G.J.2
-
23
-
-
0015426295
-
Biologic characterization of the subcutaneously implanted Lewis Lung tumor
-
Mayo JG. Biologic characterization of the subcutaneously implanted Lewis Lung tumor. Cancer Chemother Rep 1972, part 2 (3) 1, 325-330.
-
(1972)
Cancer Chemother Rep
, vol.1
, Issue.3 PART 2
, pp. 325-330
-
-
Mayo, J.G.1
-
24
-
-
0024354304
-
Determination of subcutaneous tumor size in athymic (nude) mice
-
Tomayko M.M., Reynolds C.P. Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother. Pharmacol. 24:1989;148-154.
-
(1989)
Cancer Chemother. Pharmacol.
, vol.24
, pp. 148-154
-
-
Tomayko, M.M.1
Reynolds, C.P.2
-
25
-
-
0345456676
-
UKCCCR Guidelines for the Welfare of Animals in Experimental Neoplasia, 2nd Ed.
-
UKCCCR Guidelines for the Welfare of Animals in Experimental Neoplasia, 2nd Ed. Br J Cancer 1998, 77 (1).
-
(1998)
Br J Cancer
, vol.77
, Issue.1
-
-
-
26
-
-
0026666570
-
Biochemical modification of the toxicity and antitumour effect of 5-fluorouracil and cisplatinum by WR-2721 in mice
-
Van der Wilt C.L., Van Laar J.A.M., Gyergyay F., Smid K., Peters G.J. Biochemical modification of the toxicity and antitumour effect of 5-fluorouracil and cisplatinum by WR-2721 in mice. Eur. J. Cancer. 28A:1992;2017-2024.
-
(1992)
Eur. J. Cancer
, vol.28 A
, pp. 2017-2024
-
-
Van Der Wilt, C.L.1
Van Laar, J.A.M.2
Gyergyay, F.3
Smid, K.4
Peters, G.J.5
-
27
-
-
0029043424
-
Therapy related disturbances in nucleotides in cancer cells
-
Peters G.J. Therapy related disturbances in nucleotides in cancer cells. Adv. Exp. Med. Biol. 370:1995;95-107.
-
(1995)
Adv. Exp. Med. Biol.
, vol.370
, pp. 95-107
-
-
Peters, G.J.1
-
28
-
-
0026474814
-
Effect of WR-2721 on the toxicity and antitumour activity of the combination of carboplatin and 5-fluorouracil
-
Van Laar J.A.M., Van der Wilt C.L., Treskes M., Van der Vijgh W.J.F., Peters G.J. Effect of WR-2721 on the toxicity and antitumour activity of the combination of carboplatin and 5-fluorouracil. Cancer Chemother. Pharmacol. 31:1992;97-102.
-
(1992)
Cancer Chemother. Pharmacol.
, vol.31
, pp. 97-102
-
-
Van Laar, J.A.M.1
Van Der Wilt, C.L.2
Treskes, M.3
Van Der Vijgh, W.J.F.4
Peters, G.J.5
|