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Volumn 80, Issue 7, 1999, Pages 981-990

Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non small-cell lung cancer cell lines

Author keywords

Cisplatin; DNA adducts; DNA damage; Gemcitabine; Strand breaks

Indexed keywords

CISPLATIN; GEMCITABINE; PLATINUM;

EID: 0032958512     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690452     Document Type: Article
Times cited : (185)

References (38)
  • 1
    • 0026598056 scopus 로고
    • Studies on the mechanism of the synergistic interaction between 2′-deoxy-5-azacytidine and cisplatin
    • Abbruzzese JL and Frost P (1992) Studies on the mechanism of the synergistic interaction between 2′-deoxy-5-azacytidine and cisplatin. Cancer Chem Pharmacol 30: 31-36
    • (1992) Cancer Chem Pharmacol , vol.30 , pp. 31-36
    • Abbruzzese, J.L.1    Frost, P.2
  • 3
    • 0031032211 scopus 로고    scopus 로고
    • Weekly gemcitabine with monthly cisplatin: Effective chemotherapy for advanced non-small cell lung cancer
    • Abratt RP, Bezwoda WR, Goedhals L and Hacking DJ (1997) Weekly gemcitabine with monthly cisplatin: effective chemotherapy for advanced non-small cell lung cancer. J Clin Oncol 15: 744-749
    • (1997) J Clin Oncol , vol.15 , pp. 744-749
    • Abratt, R.P.1    Bezwoda, W.R.2    Goedhals, L.3    Hacking, D.J.4
  • 5
    • 0019476174 scopus 로고
    • Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation
    • Birnboim HC and Jeveak JJ (1981) Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Cancer Res 41: 1889-1892
    • (1981) Cancer Res , vol.41 , pp. 1889-1892
    • Birnboim, H.C.1    Jeveak, J.J.2
  • 6
    • 0029593648 scopus 로고
    • Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts
    • Braakhuis BJM, Ruiz van Haperen VWT, Welters MJP and Peters GJ (1995) Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts. Eur J Cancer 31A: 1335-1340
    • (1995) Eur J Cancer , vol.31 A , pp. 1335-1340
    • Braakhuis, B.J.M.1    Ruiz Van Haperen, V.W.T.2    Welters, M.J.P.3    Peters, G.J.4
  • 7
    • 0027018878 scopus 로고
    • Inhibition of mammalian ribonucleotide reductase by cis-diamminedichloroplatinum(II)
    • Chiu CSM, Chan AK and Wright JA (1992) Inhibition of mammalian ribonucleotide reductase by cis-diamminedichloroplatinum(II). Biochem Cell Biol 70: 1132-1338.
    • (1992) Biochem Cell Biol , vol.70 , pp. 1132-1338
    • Chiu, C.S.M.1    Chan, A.K.2    Wright, J.A.3
  • 8
    • 0013554474 scopus 로고    scopus 로고
    • CalcuSyn, Windows Software for Dose Effect Analysis. Biosoft: Cambridge
    • Chou T-C and Hayball MP (1996) CalcuSyn, Windows Software for Dose Effect Analysis. Biosoft: Cambridge
    • (1996)
    • Chou, T.-C.1    Hayball, M.P.2
  • 9
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationship: The combined effects of multiple drugs on enzyme inhibitors
    • G. Weber (ed), pp. Pergamon Press: New York
    • Chou T-C and Talalay P (1983) Quantitative analysis of dose-effect relationship: the combined effects of multiple drugs on enzyme inhibitors. In Advances in Enzyme Regulation, G. Weber (ed), pp. 27-55. Pergamon Press: New York
    • (1983) Advances in Enzyme Regulation , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 10
    • 0028153260 scopus 로고
    • Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth; a rational approach to clinical protocol design
    • Chou T-C, Motzer RJ, Tong Y and Bosl GJ (1994) Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth; a rational approach to clinical protocol design. J Natl Cancer Inst 86: 1517-1524
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1517-1524
    • Chou, T.-C.1    Motzer, R.J.2    Tong, Y.3    Bosl, G.J.4
  • 12
    • 0027479992 scopus 로고
    • 2′-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation
    • Ellerhorst JA, Frost P, Abbruzzese JL, Newman RA and Chernajovsky Y (1993) 2′-deoxy-5-azacytidine increases binding of cisplatin to DNA by a mechanism independent of DNA hypomethylation. Br J Cancer 67: 209-215
    • (1993) Br J Cancer , vol.67 , pp. 209-215
    • Ellerhorst, J.A.1    Frost, P.2    Abbruzzese, J.L.3    Newman, R.A.4    Chernajovsky, Y.5
  • 13
    • 0028962811 scopus 로고
    • Validated assays for the determination of gemcitabine in human plasma and urine using high-performance liquid-chromatography with ultraviolet detection
    • Freeman KB, Anliker S, Hamilton M, Osborne D, Dhahir PH, Nelson R and Allerheiligen SRB (1995) Validated assays for the determination of gemcitabine in human plasma and urine using high-performance liquid-chromatography with ultraviolet detection. J Chromatogr Biomed Appl 665: 171-181
    • (1995) J Chromatogr Biomed Appl , vol.665 , pp. 171-181
    • Freeman, K.B.1    Anliker, S.2    Hamilton, M.3    Osborne, D.4    Dhahir, P.H.5    Nelson, R.6    Allerheiligen, S.R.B.7
  • 14
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
    • Heinemann V, Hertel LW, Grindey GB and Plunkett W (1988) Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res 48: 4024-4031
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 15
    • 0023935362 scopus 로고
    • Synthesis of 2′-deoxy-2′,2′-difluoro-D-ribose and 2′-deoxy-2′,2′-difluoro-D-ribofuranosyl nucleosides
    • Hertel LW, Kroin JS, Misner JW and Tustin JM (1988) Synthesis of 2′-deoxy-2′,2′-difluoro-D-ribose and 2′-deoxy-2′,2′-difluoro-D-ribofuranosyl nucleosides. J Org Chem 53: 2406-2409
    • (1988) J Org Chem , vol.53 , pp. 2406-2409
    • Hertel, L.W.1    Kroin, J.S.2    Misner, J.W.3    Tustin, J.M.4
  • 18
    • 0023938053 scopus 로고
    • Biochemical and molecular properties of cisplatin-resistant A2780 cells grown in folinic acid
    • Lu Y, Han J and Scanlon RJ (1988) Biochemical and molecular properties of cisplatin-resistant A2780 cells grown in folinic acid. J Biol Chem 263: 4891-4894
    • (1988) J Biol Chem , vol.263 , pp. 4891-4894
    • Lu, Y.1    Han, J.2    Scanlon, R.J.3
  • 20
    • 0000036875 scopus 로고    scopus 로고
    • Gemcitabine combined with cisplatin first line: A phase II study in patients with advanced epithelial ovarian cancer
    • (abstract 1377)
    • Nogué M, Cirera L, Arcusa M, Tusquets I, Batiste-Alentorn E, Font A and Boto B (1998) Gemcitabine combined with cisplatin first line: a phase II study in patients with advanced epithelial ovarian cancer. Proc Am Soc Clin Oncol 17: 357a (abstract 1377)
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Nogué, M.1    Cirera, L.2    Arcusa, M.3    Tusquets, I.4    Batiste-Alentorn, E.5    Font, A.6    Boto, B.7
  • 21
    • 0025799467 scopus 로고
    • Platinum DNA-damage in leucocyte DNA of patients receiving cisplatin and carboplatin chemotherapy, measured by atomic absorption spectrometry
    • Parker RJ, Gill I, Tarone R, Vionnet J, Grunberg S, Muggia F and Reed E (1991) Platinum DNA-damage in leucocyte DNA of patients receiving cisplatin and carboplatin chemotherapy, measured by atomic absorption spectrometry. Carcinogenesis 12: 1253-1258
    • (1991) Carcinogenesis , vol.12 , pp. 1253-1258
    • Parker, R.J.1    Gill, I.2    Tarone, R.3    Vionnet, J.4    Grunberg, S.5    Muggia, F.6    Reed, E.7
  • 22
    • 0023571156 scopus 로고
    • Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity
    • Peters GJ, Laurensse E, Leyva A and Pinedo HM (1987) Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity. Eur J Cancer Clin Oncol 23: 1869-1881
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 1869-1881
    • Peters, G.J.1    Laurensse, E.2    Leyva, A.3    Pinedo, H.M.4
  • 23
    • 0027287554 scopus 로고
    • Transformation of mouse fibroblasts with the oncogenes H-ras or trk is associated with pronounced changes in drug sensitivity and metabolism
    • Peters GJ, Wets M, Keepers YPAM, Oskam R, Van Ark-Otte J, Noordhuis P, Smid K and Pinedo HM (1993a) Transformation of mouse fibroblasts with the oncogenes H-ras or trk is associated with pronounced changes in drug sensitivity and metabolism. Int J Cancer 54: 450-455
    • (1993) Int J Cancer , vol.54 , pp. 450-455
    • Peters, G.J.1    Wets, M.2    Ypam, K.3    Oskam, R.4    Van Ark-Otte, J.5    Noordhuis, P.6    Smid, K.7    Pinedo, H.M.8
  • 25
    • 0027180521 scopus 로고
    • 2′,2′-Difluoro-deoxocytidine (Gemcitabine) incorporation into RNA and DNA of tumour cell lines
    • Ruiz van Haperen VWT, Veerman G, Vermorken JB and Peters GJ (1993) 2′,2′-Difluoro-deoxocytidine (Gemcitabine) incorporation into RNA and DNA of tumour cell lines. Biochem Pharmacol 46: 762-766
    • (1993) Biochem Pharmacol , vol.46 , pp. 762-766
    • Ruiz Van Haperen, V.W.T.1    Veerman, G.2    Vermorken, J.B.3    Peters, G.J.4
  • 27
    • 0028105119 scopus 로고
    • Schedule-dependence of sensitivity to 2′,2′-difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumor cell lines and solid tumors
    • Ruiz van Haperen VWT, Veerman G, Boven E, Noordhuis P, Vermorken JB and Peters GJ (1994b) Schedule-dependence of sensitivity to 2′,2′-difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumor cell lines and solid tumors. Biochem Pharmacol 48: 1327-1339
    • (1994) Biochem Pharmacol , vol.48 , pp. 1327-1339
    • Ruiz Van Haperen, V.W.T.1    Veerman, G.2    Boven, E.3    Noordhuis, P.4    Vermorken, J.B.5    Peters, G.J.6
  • 30
    • 0029848166 scopus 로고    scopus 로고
    • Phase I/II study of gemcitabine and cisplatin in non-small cell lung cancer: Preliminary results
    • Steward WP, Dunlop DJ, Dabouis G, Lacroix H and Talbot D (1996) Phase I/II study of gemcitabine and cisplatin in non-small cell lung cancer: preliminary results. Semin Oncol 5: 43-47
    • (1996) Semin Oncol , vol.5 , pp. 43-47
    • Steward, W.P.1    Dunlop, D.J.2    Dabouis, G.3    Lacroix, H.4    Talbot, D.5
  • 31
    • 0000125441 scopus 로고
    • The coordination chemistry of platinum anticancer drugs and related compounds with DNA
    • Sundquist WI and Lippard SJ (1990) The coordination chemistry of platinum anticancer drugs and related compounds with DNA. Coord Chem Rev 100: 293-322
    • (1990) Coord Chem Rev , vol.100 , pp. 293-322
    • Sundquist, W.I.1    Lippard, S.J.2
  • 32
    • 0025363447 scopus 로고
    • Correlation between cell killing by cis-diamminedichloroplatinum(II) in six mammalian cell lines and binding of a cis-diamminedichloroplatinum(II)-DNA antiserum
    • Terheggen PMAB, Emondt JY, Floot BGJ, Dijkman R, Schrier PI, Den Engelse L and Begg AC (1990) Correlation between cell killing by cis-diamminedichloroplatinum(II) in six mammalian cell lines and binding of a cis-diamminedichloroplatinum(II)-DNA antiserum. Cancer Res 50: 3556-3561
    • (1990) Cancer Res , vol.50 , pp. 3556-3561
    • Pmab, T.1    Emondt, J.Y.2    Floot, B.G.J.3    Dijkman, R.4    Schrier, P.I.5    Den Engelse, L.6    Begg, A.C.7
  • 33
    • 0026045802 scopus 로고
    • Clinical pharmacology of carboplatin
    • Van der Vijgh WJF (1991) Clinical pharmacology of carboplatin. Clin Pharmacokin 21: 242-261
    • (1991) Clin Pharmacokin , vol.21 , pp. 242-261
    • Van Der Vijgh, W.J.F.1
  • 34
    • 0031105022 scopus 로고    scopus 로고
    • Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells
    • Van der Wilt CL, Smid K, Noordhuis P, Aherne GW and Peters GJ (1997) Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells. Eur J Cancer 33: 471-478
    • (1997) Eur J Cancer , vol.33 , pp. 471-478
    • Van Der Wilt, C.L.1    Smid, K.2    Noordhuis, P.3    Aherne, G.W.4    Peters, G.J.5
  • 36
    • 0030915362 scopus 로고    scopus 로고
    • Gemcitabine: Future prospects of single-agent and combination studies
    • Van Moorsel CJA, Peters GJ and Pinedo HM (1997) Gemcitabine: future prospects of single-agent and combination studies. Oncologist 2: 127-134
    • (1997) Oncologist , vol.2 , pp. 127-134
    • Van Moorsel, C.J.A.1    Peters, G.J.2    Pinedo, H.M.3


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