메뉴 건너뛰기




Volumn 37, Issue 1-2, 2000, Pages 39-51

The cAMP signaling pathway as a therapeutic target in lymphoid malignancies

Author keywords

cAMP; Chronic lymphocytic leukemia; Lymphoid neoplasias; Malignancy; Signaling pathway; Therapeutic targets; Tumors

Indexed keywords

CHLORAMBUCIL; CILOMILAST; CILOSTAMIDE; CILOSTAZOL; CYCLIC AMP; DIPYRIDAMOLE; FORSKOLIN; METHYLXANTHINE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; ROLIPRAM; SCH 51866; SILDENAFIL; THEOPHYLLINE; UNCLASSIFIED DRUG; ZAPRINAST;

EID: 0034053448     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009057627     Document Type: Review
Times cited : (77)

References (72)
  • 1
    • 0032544181 scopus 로고    scopus 로고
    • Cilostazol has beneficial effects in treatment of intermittent claudication: Results from a multicenter, randomized, prospective, double-blind trial
    • Dawson, D. L., B. S. Cutler, M. H. Meissner, and D. E. J. Strandness. 1998. Cilostazol has beneficial effects in treatment of intermittent claudication: results from a multicenter, randomized, prospective, double-blind trial. Circulation 98:678.
    • (1998) Circulation , vol.98 , pp. 678
    • Dawson, D.L.1    Cutler, B.S.2    Meissner, M.H.3    Strandness, D.E.J.4
  • 3
    • 0032516296 scopus 로고    scopus 로고
    • Oral sildenafil in the treatment of erectile dysfunction
    • Sildenafil Study Group
    • Goldstein, I., T. Lue, H. Padma-Nathan, R. Rosen, W. Steers, and P. Wicker. 1998. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med 338:1397.
    • (1998) N Engl J Med , vol.338 , pp. 1397
    • Goldstein, I.1    Lue, T.2    Padma-Nathan, H.3    Rosen, R.4    Steers, W.5    Wicker, P.6
  • 4
    • 0015539983 scopus 로고
    • Induction of cytolysis of cultured lymphoma cells by adenosine 3′:5′-cyclic monophosphate and isolation of resistant variants
    • Daniel, V., G. Litwack, and G. M. Tompkins. 1973. Induction of cytolysis of cultured lymphoma cells by adenosine 3′:5′-cyclic monophosphate and isolation of resistant variants. Proc. Natl. Acad Sci. USA 70:76.
    • (1973) Proc. Natl. Acad Sci. USA , vol.70 , pp. 76
    • Daniel, V.1    Litwack, G.2    Tompkins, G.M.3
  • 5
    • 0016816003 scopus 로고
    • Mechanism of lymphoma cell death induced by cyclic AMP
    • Coffino, P., H. R. Bourne, and G. M. Tomkins. 1975. Mechanism of lymphoma cell death induced by cyclic AMP. Am. J. Pathol. 81:199.
    • (1975) Am. J. Pathol. , vol.81 , pp. 199
    • Coffino, P.1    Bourne, H.R.2    Tomkins, G.M.3
  • 6
    • 0025024913 scopus 로고
    • Agents that elevate cAMP stimulate DNA fragmentation in thymocytes
    • McConkey, D. J., S. Orrenius, and M. Jondal. 1990. Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J. Immunol. 145:1227.
    • (1990) J. Immunol. , vol.145 , pp. 1227
    • McConkey, D.J.1    Orrenius, S.2    Jondal, M.3
  • 7
    • 0027426206 scopus 로고
    • Distribution of cAMP in secondary follicles and its expression in B cell apoptosis and CD40-mediated survival
    • Knox, K. A., G. D. Johnson, and J. Gordon. 1993. Distribution of cAMP in secondary follicles and its expression in B cell apoptosis and CD40-mediated survival. Int. Immunol. 5:1085.
    • (1993) Int. Immunol. , vol.5 , pp. 1085
    • Knox, K.A.1    Johnson, G.D.2    Gordon, J.3
  • 8
    • 0028980745 scopus 로고
    • TGF-B1 and cyclic AMP promote apoptosis in resting human B lymphocytes
    • Lomo, J., H. K. Blomhoff, K. Beiske, T. Stokke, and E. B. Smeland. 1995. TGF-B1 and cyclic AMP promote apoptosis in resting human B lymphocytes. J. Immunol. 154:1634.
    • (1995) J. Immunol. , vol.154 , pp. 1634
    • Lomo, J.1    Blomhoff, H.K.2    Beiske, K.3    Stokke, T.4    Smeland, E.B.5
  • 11
    • 0029050664 scopus 로고
    • A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth
    • Nesterova, M., and Y. S. Cho-Chung. 1995. A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth. Nat Med 1:528.
    • (1995) Nat Med , vol.1 , pp. 528
    • Nesterova, M.1    Cho-Chung, Y.S.2
  • 12
    • 0032527802 scopus 로고    scopus 로고
    • Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide
    • Ciardiello, F., R. Caputo, R. Bianco, V. Damiano, G. Pomatico, S. Pepe, A. R. Bianco, S. Agrawal, J. Mendelsohn, and G. Tortora. 1998. Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide. JNCI 90:1087.
    • (1998) JNCI , vol.90 , pp. 1087
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3    Damiano, V.4    Pomatico, G.5    Pepe, S.6    Bianco, A.R.7    Agrawal, S.8    Mendelsohn, J.9    Tortora, G.10
  • 13
    • 0023864503 scopus 로고
    • Site-selective cAMP analogs at micromolar concentrations induce growth arrest and differentiation of acute promyelocytic, chronic myelocytic and acute lymphocytic human leukemia cell lines
    • Tortora, G., P. Tagliaferri, T. Clair, O. Colamonici, L. M. Neekers, R. K. Robins, and Y. S. Cho-Chung. 1988. Site-selective cAMP analogs at micromolar concentrations induce growth arrest and differentiation of acute promyelocytic, chronic myelocytic and acute lymphocytic human leukemia cell lines. Blood 71:230.
    • (1988) Blood , vol.71 , pp. 230
    • Tortora, G.1    Tagliaferri, P.2    Clair, T.3    Colamonici, O.4    Neekers, L.M.5    Robins, R.K.6    Cho-Chung, Y.S.7
  • 14
    • 0025753771 scopus 로고
    • 8-Chloroadenosine 3′,5′-monophosphate inhibits the growth of chinese hamster ovary and molt 4 cells through its adenosine metabolite
    • Van Lookeren Campagne, M. M., F. V. Diaz, B. Jastorff, and R. H. Kessin. 1991. 8-chloroadenosine 3′,5′-monophosphate inhibits the growth of chinese hamster ovary and Molt 4 cells through its adenosine metabolite. Cancer Res 51:1600.
    • (1991) Cancer Res , vol.51 , pp. 1600
    • Van Lookeren Campagne, M.M.1    Diaz, F.V.2    Jastorff, B.3    Kessin, R.H.4
  • 15
    • 0027490967 scopus 로고
    • Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parenteral 8-Cl-cAMP
    • Han, Z., D. Chatterjee, and J. H. Wyche. 1993. Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parenteral 8-Cl-cAMP. J Pharm Exper Therap 265:790.
    • (1993) J Pharm Exper Therap , vol.265 , pp. 790
    • Han, Z.1    Chatterjee, D.2    Wyche, J.H.3
  • 16
    • 0029123371 scopus 로고
    • Theophylline, a new inducer of apoptosis in B-CLL: Role of cylic nucleotides
    • Mentz, F., H. Merle-Beral, F. Ouaaz, and J.-L. Binet. 1995. Theophylline, a new inducer of apoptosis in B-CLL: role of cylic nucleotides. Br. J. Hematol. 90:957.
    • (1995) Br. J. Hematol. , vol.90 , pp. 957
    • Mentz, F.1    Merle-Beral, H.2    Ouaaz, F.3    Binet, J.-L.4
  • 18
    • 0032954675 scopus 로고    scopus 로고
    • Theophyl-line-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production
    • Mentz, F., H. Merle-Beral, and A. Dalloul. 1999. Theophyl-line-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production. Leukemia 13:78.
    • (1999) Leukemia , vol.13 , pp. 78
    • Mentz, F.1    Merle-Beral, H.2    Dalloul, A.3
  • 19
    • 0029797436 scopus 로고    scopus 로고
    • In vitro and in vivo anti-leukemic efficacy of cyclic AMP modulating agents against human leukemic B cell precursors
    • Myers, D., M. Chandun-Langlie, L. Chelstrom, and F. Uckun. 1996. In vitro and in vivo anti-leukemic efficacy of cyclic AMP modulating agents against human leukemic B cell precursors. Leukemia and Lymphoma 22:259.
    • (1996) Leukemia and Lymphoma , vol.22 , pp. 259
    • Myers, D.1    Chandun-Langlie, M.2    Chelstrom, L.3    Uckun, F.4
  • 20
    • 0026669254 scopus 로고
    • A simple fluorescence method for surface antigen phe-notyping of lymphocytes undergoing DNA fragmentation
    • Hardin, J. A., D. H. Sherr, M. DeMaria, and P. A. Lopez. 1992. A simple fluorescence method for surface antigen phe-notyping of lymphocytes undergoing DNA fragmentation. J. Immunol. Methods 154:99.
    • (1992) J. Immunol. Methods , vol.154 , pp. 99
    • Hardin, J.A.1    Sherr, D.H.2    DeMaria, M.3    Lopez, P.A.4
  • 21
    • 0029591322 scopus 로고
    • Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia
    • Binet, J.-L., F. Mentz, V. Leblond, and H. Merle-Beral. 1995. Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia. Leukemia 9:2159.
    • (1995) Leukemia , vol.9 , pp. 2159
    • Binet, J.-L.1    Mentz, F.2    Leblond, V.3    Merle-Beral, H.4
  • 22
    • 0033005763 scopus 로고    scopus 로고
    • Therapeutic efficacy of theophylline in chronic lymphocytic leukemia
    • Makower, D., U. Malik, Y. Novik, and P. Wiernik. 1999. Therapeutic efficacy of theophylline in chronic lymphocytic leukemia. Med Oncol 16:69.
    • (1999) Med Oncol , vol.16 , pp. 69
    • Makower, D.1    Malik, U.2    Novik, Y.3    Wiernik, P.4
  • 23
    • 0030974622 scopus 로고    scopus 로고
    • Tailoring cAMP-signalling responses through isoform multiplicity
    • Houslay, M. D., and G. Milligan. 1997. Tailoring cAMP-signalling responses through isoform multiplicity. Trends Biochem. Sci.:217.
    • (1997) Trends Biochem. Sci. , pp. 217
    • Houslay, M.D.1    Milligan, G.2
  • 24
    • 0003226768 scopus 로고    scopus 로고
    • Type 4 cyclic adenosine monophosphate phosphodiesterase as a therapeutic target in chronic lymphocytic leukemia
    • Kim, D. H., and A. Lerner. 1998. Type 4 cyclic adenosine monophosphate phosphodiesterase as a therapeutic target in chronic lymphocytic leukemia. Blood 92:2484.
    • (1998) Blood , vol.92 , pp. 2484
    • Kim, D.H.1    Lerner, A.2
  • 25
    • 0024331946 scopus 로고
    • Chemotactic peptide induces cAMP elevation in human neutrophils by amplification of the adenylate cyclase response to endogenously produced adenosine
    • Iannone, M. A., G. Wolberg, and T. P. Zimmerman. 1989. Chemotactic peptide induces cAMP elevation in human neutrophils by amplification of the adenylate cyclase response to endogenously produced adenosine. J Biol Chem 264:20177.
    • (1989) J Biol Chem , vol.264 , pp. 20177
    • Iannone, M.A.1    Wolberg, G.2    Zimmerman, T.P.3
  • 26
    • 0023162087 scopus 로고
    • Identification and characterization of Ca2+-calmodulin-sensitive cyclic nucleotide phosphodiesterase in a human lymphoblastoid cell line
    • Epstein, P. M., S. Moraski, and R. Hachisu. 1987. Identification and characterization of Ca2+-calmodulin-sensitive cyclic nucleotide phosphodiesterase in a human lymphoblastoid cell line. Biochem. J. 243:533.
    • (1987) Biochem. J. , vol.243 , pp. 533
    • Epstein, P.M.1    Moraski, S.2    Hachisu, R.3
  • 27
    • 0017726762 scopus 로고
    • Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells
    • Epstein, P. M., J. S. Mills, C. P. Ross, S. J. Strada, E. M. Hersh, and W. J. Thompson. 1977. Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells. Cancer Res. 37:4016.
    • (1977) Cancer Res. , vol.37 , pp. 4016
    • Epstein, P.M.1    Mills, J.S.2    Ross, C.P.3    Strada, S.J.4    Hersh, E.M.5    Thompson, W.J.6
  • 28
    • 0025284702 scopus 로고
    • Induction of a calcium/calmodulin-dependent phosphodiesterase during PHA-stimulated lymphocyte mitogenesis
    • Hurwitz, R. L., K. M. Hirsch, D. J. Clark, V. N. Holcombe, and M. Y. Hurwitz. 1990. Induction of a calcium/calmodulin-dependent phosphodiesterase during PHA-stimulated lymphocyte mitogenesis. J. Biol. Chem. 265:8901.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8901
    • Hurwitz, R.L.1    Hirsch, K.M.2    Clark, D.J.3    Holcombe, V.N.4    Hurwitz, M.Y.5
  • 30
    • 0031887507 scopus 로고    scopus 로고
    • Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation
    • Gantner, F., C. Gotz, V. Gekeler, C. Schudt, A. Wendel, and A. Hatzelmann. 1998. Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation. Br J Pharmacol 123:1031.
    • (1998) Br J Pharmacol , vol.123 , pp. 1031
    • Gantner, F.1    Gotz, C.2    Gekeler, V.3    Schudt, C.4    Wendel, A.5    Hatzelmann, A.6
  • 31
    • 0029745055 scopus 로고    scopus 로고
    • Inhibition of calmodulin dependent phosphodiesterase induces apoptosis in human leukemic cells
    • Jiang, X., J. Li, M. Paskind, and P. M. Epstein. 1996. Inhibition of calmodulin dependent phosphodiesterase induces apoptosis in human leukemic cells. Proc. Natl. Acad. Sci. USA 93:11236.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11236
    • Jiang, X.1    Li, J.2    Paskind, M.3    Epstein, P.M.4
  • 32
    • 85011468695 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: Possible role for protein kinase b but not mitogen-activated protein kinase or p70 S6 kinase
    • Wijkander, J., T. R. Landstrom, V. Manganiello, P. Belfrage, and E. Degerman. 1998. Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase. Endocrinology 139:219.
    • (1998) Endocrinology , vol.139 , pp. 219
    • Wijkander, J.1    Landstrom, T.R.2    Manganiello, V.3    Belfrage, P.4    Degerman, E.5
  • 33
    • 0025314048 scopus 로고
    • Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: Inhibition of cyclic AMP breakdown by cyclic GMP
    • Maurice, D. H., and R. J. Haslam. 1990. Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. Mol Pharmacol 37:671.
    • (1990) Mol Pharmacol , vol.37 , pp. 671
    • Maurice, D.H.1    Haslam, R.J.2
  • 35
    • 0029833842 scopus 로고    scopus 로고
    • Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CDS+ T-lymphocytes: Role in regulating proliferation and the biosynthesis of interleukin-2
    • Giembycz, M. A., C. J. Corrigan, J. Seybold, R. Newton, and P. J. Barnes. 1996. Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CDS+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2. British Journal of Pharmacology 118:1945.
    • (1996) British Journal of Pharmacology , vol.118 , pp. 1945
    • Giembycz, M.A.1    Corrigan, C.J.2    Seybold, J.3    Newton, R.4    Barnes, P.J.5
  • 36
    • 0031028090 scopus 로고    scopus 로고
    • Challenge of human Jurkat T cells with the adenylate cyclase activator forskolin elicits major changes in cAMP PDE expression by up-regulating PDE3 and inducing PDE4DI and PDE4D2 splice variants as well as down regulating a novel PDE4A splice variant
    • Erdogan, S., and M. D. Houslay. 1997. Challenge of human Jurkat T cells with the adenylate cyclase activator forskolin elicits major changes in cAMP PDE expression by up-regulating PDE3 and inducing PDE4DI and PDE4D2 splice variants as well as down regulating a novel PDE4A splice variant. Biochem. J. 321:165.
    • (1997) Biochem. J. , vol.321 , pp. 165
    • Erdogan, S.1    Houslay, M.D.2
  • 37
    • 0032493818 scopus 로고    scopus 로고
    • Induction of phosphodiesterases 3A, 4A4, 4D1, 4D2 and 4D3 in Jurkat T cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor antagonists
    • Seybold, J., R. Newton, L. Wright, P. A. Finney, N. Suttorp, P. J. Barnes, I. M. Adcock, and M. A. Giembycz. 1998. Induction of phosphodiesterases 3A, 4A4, 4D1, 4D2 and 4D3 in Jurkat T cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor antagonists. J Biol Chem 273:20575.
    • (1998) J Biol Chem , vol.273 , pp. 20575
    • Seybold, J.1    Newton, R.2    Wright, L.3    Finney, P.A.4    Suttorp, N.5    Barnes, P.J.6    Adcock, I.M.7    Giembycz, M.A.8
  • 38
    • 0031601339 scopus 로고    scopus 로고
    • The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: Intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions
    • Houslay, M. D., M. Sullivan, and G. B. Bolger. 1998. The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions. Advances in Pharmacology 44:225.
    • (1998) Advances in Pharmacology , vol.44 , pp. 225
    • Houslay, M.D.1    Sullivan, M.2    Bolger, G.B.3
  • 40
    • 0026996701 scopus 로고
    • Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity
    • Torphy, T. J., H. L. Zhou, and L. B. Cieslinski. 1992. Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity. J. Pharmacol. Exper. Ther. 263:1195.
    • (1992) J. Pharmacol. Exper. Ther. , vol.263 , pp. 1195
    • Torphy, T.J.1    Zhou, H.L.2    Cieslinski, L.B.3
  • 41
    • 0028231180 scopus 로고
    • Effects of rolipram on responses to acute and chronic antigen exposure in monkeys
    • Turner, C. R., C. J. Andresen, W. B. Smith, and J. W. Watson. 1994. Effects of rolipram on responses to acute and chronic antigen exposure in monkeys. Am J Res Crit Care Med 14:1153.
    • (1994) Am J Res Crit Care Med , vol.14 , pp. 1153
    • Turner, C.R.1    Andresen, C.J.2    Smith, W.B.3    Watson, J.W.4
  • 43
    • 0027315234 scopus 로고
    • The specific type IV PDE inhibitor rolipram suppresses tumor necrosis factor alpha production by human mononuclear cells
    • Semmler, J., H. Wachtel, and S. Endres. 1993. The specific type IV PDE inhibitor rolipram suppresses tumor necrosis factor alpha production by human mononuclear cells. Int. J. Immunopharmacol. 15:409.
    • (1993) Int. J. Immunopharmacol. , vol.15 , pp. 409
    • Semmler, J.1    Wachtel, H.2    Endres, S.3
  • 44
    • 0028957419 scopus 로고
    • Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs
    • Platzer, C., C. Meisel, K. Vogt, M. Platzer, and H. D. Volk. 1995. Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int Immunol 7:517.
    • (1995) Int Immunol , vol.7 , pp. 517
    • Platzer, C.1    Meisel, C.2    Vogt, K.3    Platzer, M.4    Volk, H.D.5
  • 45
    • 0029962380 scopus 로고    scopus 로고
    • Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: Analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine(EHNA) and rolipram
    • Michie, A. M., M. Lobban, T. Muller, M. M. Harnett, and M. D. Houslay. 1996. Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine(EHNA) and rolipram. Cellular Signalling 8:97.
    • (1996) Cellular Signalling , vol.8 , pp. 97
    • Michie, A.M.1    Lobban, M.2    Muller, T.3    Harnett, M.M.4    Houslay, M.D.5
  • 46
    • 0033556705 scopus 로고    scopus 로고
    • Specific CD3 epsilon association of a phosphodiesterase 4B isoform determines its selective tyrosine phosphorylation after CD3 ligation
    • Baroja, M. L., L. B. Cieslinski, T. J. Torphy, R. L. Wange, and J. Madrenas. 1999. Specific CD3 epsilon association of a phosphodiesterase 4B isoform determines its selective tyrosine phosphorylation after CD3 ligation. J Immunol 162:2016.
    • (1999) J Immunol , vol.162 , pp. 2016
    • Baroja, M.L.1    Cieslinski, L.B.2    Torphy, T.J.3    Wange, R.L.4    Madrenas, J.5
  • 47
    • 0027164208 scopus 로고
    • Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient saccharomyces cerevisiae
    • Michaeli, T., T. J. Bloom, T. Martins, K. Loughney, K. Ferguson, M. Riggs, L. Rodgers, J. A. Beavo, and M. Wigler. 1993. Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae. J Biol Chem 268:12925.
    • (1993) J Biol Chem , vol.268 , pp. 12925
    • Michaeli, T.1    Bloom, T.J.2    Martins, T.3    Loughney, K.4    Ferguson, K.5    Riggs, M.6    Rodgers, L.7    Beavo, J.A.8    Wigler, M.9
  • 48
    • 0030459832 scopus 로고    scopus 로고
    • Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants
    • Bloom, T. J., and J. A. Beavo. 1996. Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants. Proc. Natl. Acad. USA 93:14188.
    • (1996) Proc. Natl. Acad. USA , vol.93 , pp. 14188
    • Bloom, T.J.1    Beavo, J.A.2
  • 49
    • 0033524977 scopus 로고    scopus 로고
    • CD3 and CD28-dependent induction of PDE7 required for T cell activation
    • Li, L., C. Yee, and J. A. Beavo. 1999. CD3 and CD28-dependent induction of PDE7 required for T cell activation. Science 283:848.
    • (1999) Science , vol.283 , pp. 848
    • Li, L.1    Yee, C.2    Beavo, J.A.3
  • 50
    • 0343095111 scopus 로고
    • Catalytic and kinetic properties of purified high affin-ity cAMP phosphodiesterase from dog kidney
    • Epstein, P. M., S. J. Strada, K. Sarada, and W. J. Thompson. 1982. Catalytic and kinetic properties of purified high affin-ity cAMP phosphodiesterase from dog kidney. Arch Biochem Biophys 215:183.
    • (1982) Arch Biochem Biophys , vol.215 , pp. 183
    • Epstein, P.M.1    Strada, S.J.2    Sarada, K.3    Thompson, W.J.4
  • 52
    • 0026528829 scopus 로고
    • Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast
    • Torphy, T. J., J. M. Stadel, M. Burman, L. B. Cieslinski, M. M. McLaughlin, J. R. White, and G. P. Livi. 1992. Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast. J Biol Chem 267:1798.
    • (1992) J Biol Chem , vol.267 , pp. 1798
    • Torphy, T.J.1    Stadel, J.M.2    Burman, M.3    Cieslinski, L.B.4    McLaughlin, M.M.5    White, J.R.6    Livi, G.P.7
  • 53
    • 0030925148 scopus 로고    scopus 로고
    • Proposal for pharmacologically distinct conformers of PDE4 cAMP phosphodiesterases
    • Souness, J. E., and S. Rao. 1997. Proposal for pharmacologically distinct conformers of PDE4 cAMP phosphodiesterases. Cell Signal 9:227.
    • (1997) Cell Signal , vol.9 , pp. 227
    • Souness, J.E.1    Rao, S.2
  • 56
    • 0029812555 scopus 로고    scopus 로고
    • The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)
    • O'Connell, J. C., J. F. McCallum, I. McPhee, J. Wakefield, E. S. Houslay, W. Wishart, G. Bolger, M. Frame, and M. D. Houslay. 1996. The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5). Biochem. J. 318:255.
    • (1996) Biochem. J. , vol.318 , pp. 255
    • O'Connell, J.C.1    McCallum, J.F.2    McPhee, I.3    Wakefield, J.4    Houslay, E.S.5    Wishart, W.6    Bolger, G.7    Frame, M.8    Houslay, M.D.9
  • 57
    • 0039181708 scopus 로고    scopus 로고
    • Selective activation of rolipram-sensitive, cAMP-specific phosphodiesterase isoforms by phosphatidic acid
    • Nemoz, G., C. Sette, and M. Conti. 1997. Selective activation of rolipram-sensitive, cAMP-specific phosphodiesterase isoforms by phosphatidic acid. Mol Pharmacol 51:242.
    • (1997) Mol Pharmacol , vol.51 , pp. 242
    • Nemoz, G.1    Sette, C.2    Conti, M.3
  • 59
    • 0027955125 scopus 로고
    • Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells
    • Fluckiger, A.-C., I. Durand, and J. Banchereau. 1994. Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells. J Exp Med 179:91.
    • (1994) J Exp Med , vol.179 , pp. 91
    • Fluckiger, A.-C.1    Durand, I.2    Banchereau, J.3
  • 61
    • 0025361921 scopus 로고
    • Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia cells: A possible regulatory role of TNF in the progression of the disease
    • Foa, R., M. Massaia, S. Cardona, A. Tos, A. Bianchi, C. Attisano, A. Guarini, P. di Celle, and M. Fierro. 1990. Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia cells: a possible regulatory role of TNF in the progression of the disease. Blood 76:393.
    • (1990) Blood , vol.76 , pp. 393
    • Foa, R.1    Massaia, M.2    Cardona, S.3    Tos, A.4    Bianchi, A.5    Attisano, C.6    Guarini, A.7    Di Celle, P.8    Fierro, M.9
  • 63
    • 0029937459 scopus 로고    scopus 로고
    • Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia
    • Reittie, J., K. L. Yong, P. Panayiotidis, and A. V. Hoffbrand. 1996. Interleukin-6 inhibits apoptosis and tumour necrosis factor induced proliferation of B-chronic lymphocytic leukaemia. Leukemia in & Lymphoma 22:83.
    • (1996) Leukemia in & Lymphoma , vol.22 , pp. 83
    • Reittie, J.1    Yong, K.L.2    Panayiotidis, P.3    Hoffbrand, A.V.4
  • 65
    • 0027448876 scopus 로고
    • Modulation of rat thymocyte proliferative response through the inhibition of different cyclic nucleotide phosphodiesterase isoforms by means of selective inhibitors and cGMP-elevating agents
    • Marcoz, P., A. F. Prigent, M. Lagarde, and G. Nemoz. 1993. Modulation of rat thymocyte proliferative response through the inhibition of different cyclic nucleotide phosphodiesterase isoforms by means of selective inhibitors and cGMP-elevating agents. Mol. Pharmacol. 44:1027.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 1027
    • Marcoz, P.1    Prigent, A.F.2    Lagarde, M.3    Nemoz, G.4
  • 66
    • 0031611368 scopus 로고    scopus 로고
    • Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes
    • Jiang, X., M. Paskind, R. Weltzien, and P. M. Epstein. 1998. Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes. Cell Biochem Biophys. 28:135.
    • (1998) Cell Biochem Biophys. , vol.28 , pp. 135
    • Jiang, X.1    Paskind, M.2    Weltzien, R.3    Epstein, P.M.4
  • 68
    • 0027280561 scopus 로고
    • Interactions of a G-protein with its effector: Transducin and cGMP phosphodiesterase in retinal rods
    • Pfister, C., N. Bennett, F. Bruckert, P. Catty, A. Clerc, F. Pages, and P. Deterre. 1993. Interactions of a G-protein with its effector: transducin and cGMP phosphodiesterase in retinal rods. Cell Signal 5:235.
    • (1993) Cell Signal , vol.5 , pp. 235
    • Pfister, C.1    Bennett, N.2    Bruckert, F.3    Catty, P.4    Clerc, A.5    Pages, F.6    Deterre, P.7
  • 69
    • 0032555138 scopus 로고    scopus 로고
    • Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase
    • Soderling, S. H., S. J. Bayuga, and J. A. Beavo. 1998. Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. Proc. Natl. Acad. Sci. USA 95:8991.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8991
    • Soderling, S.H.1    Bayuga, S.J.2    Beavo, J.A.3
  • 70
    • 0032546779 scopus 로고    scopus 로고
    • Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase
    • Fisher, D. A., J. F. Smith, J. S. Pillar, S. H. St. Denis, and J. B. Cheng. 1998. Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase. J. Biol. Chem. 273:15559.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15559
    • Fisher, D.A.1    Smith, J.F.2    Pillar, J.S.3    St. Denis, S.H.4    Cheng, J.B.5
  • 71
    • 0033603598 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)
    • Fujishige, K., J. Kotera, H. Michibata, K. Yuasa, S. Takebayashi, K. Okumura, and K. Omori. 1999. Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A). J Biol Chem 274:18438.
    • (1999) J Biol Chem , vol.274 , pp. 18438
    • Fujishige, K.1    Kotera, J.2    Michibata, H.3    Yuasa, K.4    Takebayashi, S.5    Okumura, K.6    Omori, K.7
  • 72
    • 0033536020 scopus 로고    scopus 로고
    • Isolation and characterization of a dual substrate phosphodiesterase gene family: PDE10A
    • Soderling, S. H., S. J. Bayuga, and J. A. Beavo. 1999. Isolation and characterization of a dual substrate phosphodiesterase gene family: PDE10A. Proc. Natl. Acad. Sci. USA. 96:7071.
    • (1999) Proc. Natl. Acad. Sci. USA. , vol.96 , pp. 7071
    • Soderling, S.H.1    Bayuga, S.J.2    Beavo, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.