Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T- cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and G(s)- coupled receptor agonists: Potential role in β2-adrenoreceptor desensitization

Journal of Biological Chemistry

Volumn 273, Issue 32, 1998, Pages 20575-20588

  Seybold, Joachim ^a,b   Newton, Robert ^a   Wright, Lyndon ^a   Finney, Paul A ^a   Suttorp, Norbert ^a   Barnes, Peter J ^a   Adcock, Ian M ^a   Giembyc, Mark A ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR;

ALLERGIC DISEASE; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME DEGRADATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; T LYMPHOCYTE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ADRENERGIC BETA-AGONISTS; ASTHMA; CYCLIC AMP; DINOPROSTONE; ENZYME INHIBITORS; FENOTEROL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GTP-BINDING PROTEINS; HUMANS; ISOPROTERENOL; JURKAT CELLS; PHOSPHORIC DIESTER HYDROLASES; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; T-LYMPHOCYTES; UP-REGULATION;

EID: 0032493818     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.32.20575     Document Type: Article

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