Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 20, 1996, Pages 11236-11241

  Jiang, Xin ^a   Li, Jianping ^a   Paskind, Michael ^b   Epstein, Paul M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b BASF Bioresearch Corporation   (United States)

Author keywords

antisense; cAMP; cell death; leukemia

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PHOSPHODIESTERASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; LEUKEMIA CELL LINE; OPEN READING FRAME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; AMINO ACID SEQUENCE; APOPTOSIS; B-LYMPHOCYTES; BASE SEQUENCE; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MITOGENS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PYRROLIDINONES; RNA, MESSENGER; ROLIPRAM; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES; TUMOR CELLS, CULTURED; VINCA ALKALOIDS;

BOVINAE;

EID: 0029745055     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.20.11236     Document Type: Article

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