Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant

Biochemical Journal

Volumn 321, Issue 1, 1997, Pages 165-175

  Erdogan, Suat ^a,b   Houslay, Miles D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b MUSTAFA KEMAL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ADENYLATE CYCLASE ACTIVATOR; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP PHOSPHODIESTERASE; DACTINOMYCIN; FORSKOLIN; ISOENZYME; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LEUKEMIA CELL LINE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ADENYLATE CYCLASE; BASE SEQUENCE; CHOLERA TOXIN; DOWN-REGULATION; ENZYME INDUCTION; FORSKOLIN; HUMANS; ISOENZYMES; JURKAT CELLS; MOLECULAR SEQUENCE DATA; PHOSPHORIC DIESTER HYDROLASES; RNA SPLICING; UP-REGULATION;

EID: 0031028090     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3210165     Document Type: Article

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