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Volumn 88, Issue 6, 1996, Pages 2172-2182

Theophylline synergizes with chlorambucil in inducing apoptosis of B- chronic lymphocytic leukemia cells

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CHLORAMBUCIL; INTERLEUKIN 4; MYC PROTEIN; PROTEIN BCL 2; PROTEIN P53; THEOPHYLLINE;

EID: 0029815706     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.6.2172.bloodjournal8862172     Document Type: Article
Times cited : (94)

References (65)
  • 1
    • 0024492086 scopus 로고
    • Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T-cells in thymic culture
    • Smith CA, Williams GT, Kingston R, Jenkinson EJ, Owen JJT: Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T-cells in thymic culture. Nature 337:181, 1989
    • (1989) Nature , vol.337 , pp. 181
    • Smith, C.A.1    Williams, G.T.2    Kingston, R.3    Jenkinson, E.J.4    Owen, J.J.T.5
  • 2
    • 0026043871 scopus 로고
    • Induction of apoptosis during normal and neoplastic B-cell development in the bursa of fabricius
    • Nieman PE, Thomas SJ, Loring G: Induction of apoptosis during normal and neoplastic B-cell development in the bursa of fabricius. Proc Natl Acad Sci USA 88:5857, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5857
    • Nieman, P.E.1    Thomas, S.J.2    Loring, G.3
  • 3
    • 0025899138 scopus 로고
    • Programmed cell death: Apoptosis and oncogenesis
    • Williams GT: Programmed cell death: Apoptosis and oncogenesis. Cell 65:1097, 1991
    • (1991) Cell , vol.65 , pp. 1097
    • Williams, G.T.1
  • 4
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haematopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM: Bcl-2 gene promotes haematopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440, 1988
    • (1988) Nature , vol.335 , pp. 440
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 5
    • 0024556599 scopus 로고
    • Spontaneous programmed death (apoptosis) of B chronic lymphocytic leukemia cells following their culture in vitro
    • Collins RJ, Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JFR: Spontaneous programmed death (apoptosis) of B chronic lymphocytic leukemia cells following their culture in vitro. Br J Haematol 71:343, 1989
    • (1989) Br J Haematol , vol.71 , pp. 343
    • Collins, R.J.1    Verschuer, L.A.2    Harmon, B.V.3    Prentice, R.L.4    Pope, J.H.5    Kerr, J.F.R.6
  • 7
    • 0027505303 scopus 로고
    • Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-β-D-arabinofuranosyl-2-fluoroadenine
    • Robertson LE, Chubb S, Meyn RE, Story M, Ford R, Hittelman WN, Plunkett W: Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-β-D-arabinofuranosyl-2-fluoroadenine. Blood 81:143, 1993
    • (1993) Blood , vol.81 , pp. 143
    • Robertson, L.E.1    Chubb, S.2    Meyn, R.E.3    Story, M.4    Ford, R.5    Hittelman, W.N.6    Plunkett, W.7
  • 8
    • 0028204418 scopus 로고
    • Chlorambucil induced apoptosis in chronic lymphocytic leukemia (CLL) and its relationship to clinical efficiency
    • Begleiter A, Lee K, Israels LG, Mowat MR, Johnston JB: Chlorambucil induced apoptosis in chronic lymphocytic leukemia (CLL) and its relationship to clinical efficiency. Leuk Lymphoma 8:103, 1994 suppl 1
    • (1994) Leuk Lymphoma , vol.8 , Issue.1 SUPPL. , pp. 103
    • Begleiter, A.1    Lee, K.2    Israels, L.G.3    Mowat, M.R.4    Johnston, J.B.5
  • 9
    • 0026584181 scopus 로고
    • Induction of apoptosis in chronic lymphocytic leukemia cells and its prevention by phorbol ester
    • Forbes IJ, Zalewski PD, Giannakis C, Cowled PA: Induction of apoptosis in chronic lymphocytic leukemia cells and its prevention by phorbol ester. Exp Cell Res 198:367, 1992
    • (1992) Exp Cell Res , vol.198 , pp. 367
    • Forbes, I.J.1    Zalewski, P.D.2    Giannakis, C.3    Cowled, P.A.4
  • 10
    • 0029123371 scopus 로고
    • Theophylline, a new inducer of apoptosis in B-CLL. Role of cyclic nucleotides
    • Mentz F, Merle-Béral H, Ouaaz F, Binet JL: Theophylline, a new inducer of apoptosis in B-CLL. Role of cyclic nucleotides. Br J Haematol 90:957, 1995
    • (1995) Br J Haematol , vol.90 , pp. 957
    • Mentz, F.1    Merle-Béral, H.2    Ouaaz, F.3    Binet, J.L.4
  • 11
    • 0027955125 scopus 로고
    • Interleukin 10 induces apoptotic cell death of B chronic lymphocytic leukemia cells
    • Fluckiger AC, Durand I, Banchereau J: Interleukin 10 induces apoptotic cell death of B chronic lymphocytic leukemia cells. J Exp Med 179:91, 1994
    • (1994) J Exp Med , vol.179 , pp. 91
    • Fluckiger, A.C.1    Durand, I.2    Banchereau, J.3
  • 12
    • 0027936671 scopus 로고
    • Interleukin-5 (IL-5) increases spontaneous apoptosis of B-cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression and is inhibited by IL-4
    • Mainou-Fowler T, Craig VA, Copplestone JA, Hamon MD, Prentice AG: Interleukin-5 (IL-5) increases spontaneous apoptosis of B-cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression and is inhibited by IL-4. Blood 84:2297, 1994
    • (1994) Blood , vol.84 , pp. 2297
    • Mainou-Fowler, T.1    Craig, V.A.2    Copplestone, J.A.3    Hamon, M.D.4    Prentice, A.G.5
  • 13
    • 0026754538 scopus 로고
    • Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and up regulates Bcl-2 expression
    • Dancescu M, Rubio-Trujillo M, Biron G, Bron D, Delespesse G, Sarfati M: Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and up regulates Bcl-2 expression. J Exp Med 176:1319, 1992
    • (1992) J Exp Med , vol.176 , pp. 1319
    • Dancescu, M.1    Rubio-Trujillo, M.2    Biron, G.3    Bron, D.4    Delespesse, G.5    Sarfati, M.6
  • 16
    • 0027196547 scopus 로고
    • Control of programmed cell death in normal and leukemic cells: New implications for therapy
    • Sachs L, Lotem J: Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood 82:15, 1993
    • (1993) Blood , vol.82 , pp. 15
    • Sachs, L.1    Lotem, J.2
  • 18
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer SJ: Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 80:879, 1992
    • (1992) Blood , vol.80 , pp. 879
    • Korsmeyer, S.J.1
  • 21
    • 0027999617 scopus 로고
    • Structure and function of p53 in normal cells and their aberration in cancer cells: Projection on the hematologic cell lineages
    • Prokocimer M, Rotter V: Structure and function of p53 in normal cells and their aberration in cancer cells: Projection on the hematologic cell lineages. Blood 84:2391, 1994
    • (1994) Blood , vol.84 , pp. 2391
    • Prokocimer, M.1    Rotter, V.2
  • 23
    • 0027246692 scopus 로고
    • Regulation by Bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation competent and defective myeloid leukemic cells
    • Lotem J, Sachs L: Regulation by Bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation competent and defective myeloid leukemic cells. Cell Growth Differ 4:41, 1993
    • (1993) Cell Growth Differ , vol.4 , pp. 41
    • Lotem, J.1    Sachs, L.2
  • 25
    • 0026670335 scopus 로고
    • Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview
    • Wyllie AH: Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview. Cancer Metastatis Rev 11:95, 1992
    • (1992) Cancer Metastatis Rev , vol.11 , pp. 95
    • Wyllie, A.H.1
  • 27
  • 29
    • 0011390625 scopus 로고
    • The cyclic AMP cascade: A signal transduction system
    • Kebabian JW: The cyclic AMP cascade: A signal transduction system. Neurotransmissions 2:1, 1992
    • (1992) Neurotransmissions , vol.2 , pp. 1
    • Kebabian, J.W.1
  • 30
    • 0026781986 scopus 로고
    • BCL-2 gene transfer increases relative resistance of S49.1 and WEH 17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
    • Miyashita T, Reed JC: BCL-2 gene transfer increases relative resistance of S49.1 and WEH 17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 52:5407, 1992
    • (1992) Cancer Res , vol.52 , pp. 5407
    • Miyashita, T.1    Reed, J.C.2
  • 31
    • 0027239823 scopus 로고
    • Bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC: bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82:1820, 1993
    • (1993) Blood , vol.82 , pp. 1820
    • Hanada, M.1    Delia, D.2    Aiello, A.3    Stadtmauer, E.4    Reed, J.C.5
  • 32
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC: Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 81:151, 1993
    • (1993) Blood , vol.81 , pp. 151
    • Miyashita, T.1    Reed, J.C.2
  • 33
    • 0025308478 scopus 로고
    • The dose dependent effect of cyclic AMP on ribonucleotide reductase in mitogen stimulated mononuclear cells
    • Albert D, Kowalski J, Nodzenski E, Micek M, Wu P: The dose dependent effect of cyclic AMP on ribonucleotide reductase in mitogen stimulated mononuclear cells. Biochem Biophys Res Commun 167:383, 1990
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 383
    • Albert, D.1    Kowalski, J.2    Nodzenski, E.3    Micek, M.4    Wu, P.5
  • 34
    • 0025230674 scopus 로고
    • Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage
    • Kizaki H, Suzuki K, Tadakuma T, Ishimura Y: Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage. J Biol Chem 265:5280, 1990
    • (1990) J Biol Chem , vol.265 , pp. 5280
    • Kizaki, H.1    Suzuki, K.2    Tadakuma, T.3    Ishimura, Y.4
  • 35
    • 0025024913 scopus 로고
    • Agents that elevate cAMP stimulate DNA fragmentation in thymocytes
    • McConkey DJ, Orrenius S, Jondal M: Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J Immunol 145:1227, 1990
    • (1990) J Immunol , vol.145 , pp. 1227
    • McConkey, D.J.1    Orrenius, S.2    Jondal, M.3
  • 36
    • 0029022778 scopus 로고
    • Involvement of cAMP in CD3/T cell receptor complex- and CD2-mediated apoptosis of human thymocytes
    • Mentz F, Mossalayi MD, Ouaaz F, Debré P: Involvement of cAMP in CD3/T cell receptor complex- and CD2-mediated apoptosis of human thymocytes. Eur J Immunol 25:1798, 1995
    • (1995) Eur J Immunol , vol.25 , pp. 1798
    • Mentz, F.1    Mossalayi, M.D.2    Ouaaz, F.3    Debré, P.4
  • 37
    • 0028980745 scopus 로고
    • TGFβ1 and cyclic AMP promote apoptosis in resting human B lymphocytes
    • Lomo J, Blomhoff HK, Beiske K, Stokke T, Smeland EB: TGFβ1 and cyclic AMP promote apoptosis in resting human B lymphocytes. J Immunol 154:1634, 1995
    • (1995) J Immunol , vol.154 , pp. 1634
    • Lomo, J.1    Blomhoff, H.K.2    Beiske, K.3    Stokke, T.4    Smeland, E.B.5
  • 38
    • 0027426206 scopus 로고
    • Distribution of cAMP in secondary follicles and its expression in B cell apoptosis and CD40-mediated survival
    • Knox KA, Johnson GD, Gordon J: Distribution of cAMP in secondary follicles and its expression in B cell apoptosis and CD40-mediated survival. Int Immunol 5:1085, 1993
    • (1993) Int Immunol , vol.5 , pp. 1085
    • Knox, K.A.1    Johnson, G.D.2    Gordon, J.3
  • 39
    • 0028278181 scopus 로고
    • Signal transduction and gene regulation: The nuclear response to cAMP
    • Lalli E, Sassone-Corsi P: Signal transduction and gene regulation: The nuclear response to cAMP. J Biol Chem 269:17359, 1994
    • (1994) J Biol Chem , vol.269 , pp. 17359
    • Lalli, E.1    Sassone-Corsi, P.2
  • 40
    • 0021367846 scopus 로고
    • Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
    • Cohen JJ, Duke RC: Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38, 1984
    • (1984) J Immunol , vol.132 , pp. 38
    • Cohen, J.J.1    Duke, R.C.2
  • 41
    • 0027360460 scopus 로고
    • Protein tyrosine phosphorylation is mandatory for CD40-mediated rescue of germinal center B cells from apoptosis
    • Knox KA, Gordon J: Protein tyrosine phosphorylation is mandatory for CD40-mediated rescue of germinal center B cells from apoptosis. Eur J Immunol 23:2578, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 2578
    • Knox, K.A.1    Gordon, J.2
  • 42
    • 0027582265 scopus 로고
    • Apoptosis and signal transduction: Clues to a molecular mechanism
    • Lee S, Christakos S, Small MB: Apoptosis and signal transduction: Clues to a molecular mechanism. Curr Opin Cell Biol 5:286, 1993
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 286
    • Lee, S.1    Christakos, S.2    Small, M.B.3
  • 46
    • 0027318216 scopus 로고
    • Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma
    • Frankfurt OS, Byrnes JJ, Seckinger D, Sugarbaker EV: Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma. Oncol Res 5:37, 1993
    • (1993) Oncol Res , vol.5 , pp. 37
    • Frankfurt, O.S.1    Byrnes, J.J.2    Seckinger, D.3    Sugarbaker, E.V.4
  • 47
    • 0025837444 scopus 로고
    • Anti-proliferative effect of interleukin-4 in B chronic lymphocytic leukemia
    • Luo HY, Ruhio M, Biron G, Delespesse G, Sarfati M: Anti-proliferative effect of interleukin-4 in B chronic lymphocytic leukemia. J Immunother 10:418, 1991
    • (1991) J Immunother , vol.10 , pp. 418
    • Luo, H.Y.1    Ruhio, M.2    Biron, G.3    Delespesse, G.4    Sarfati, M.5
  • 49
    • 0027379859 scopus 로고
    • Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukaemia cells in vitro
    • Panayiotidis P, Ganeshaguru K, Jabbar SAB, Hoffbrand V: Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukaemia cells in vitro. Br J Haematol 85:439, 1993
    • (1993) Br J Haematol , vol.85 , pp. 439
    • Panayiotidis, P.1    Ganeshaguru, K.2    Jabbar, S.A.B.3    Hoffbrand, V.4
  • 50
    • 0028258895 scopus 로고
    • Interleukin-4 induces programmed cell death (apoptosis) in cases of high-risk acute lymphoblastic leukemia
    • Manabe A, Coustan-Smith E, Kumagai M, Behm FG, Raimondi SC, Pui CH, Campana D: Interleukin-4 induces programmed cell death (apoptosis) in cases of high-risk acute lymphoblastic leukemia. Blood 83:1731, 1994
    • (1994) Blood , vol.83 , pp. 1731
    • Manabe, A.1    Coustan-Smith, E.2    Kumagai, M.3    Behm, F.G.4    Raimondi, S.C.5    Pui, C.H.6    Campana, D.7
  • 51
    • 0025826999 scopus 로고
    • Expression of interleukin-4 receptors on early human B-lineage cells
    • Law CL, Armitage RJ, Villablanca JG, LeBien TW: Expression of interleukin-4 receptors on early human B-lineage cells. Blood 78:703, 1991
    • (1991) Blood , vol.78 , pp. 703
    • Law, C.L.1    Armitage, R.J.2    Villablanca, J.G.3    LeBien, T.W.4
  • 53
    • 0025751550 scopus 로고
    • BCL-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ:BCL-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879, 1991
    • (1991) Cell , vol.67 , pp. 879
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 54
    • 0026722655 scopus 로고
    • Cooperative interaction between c-myc and bcl-2 proto-oncogenes
    • Fanidi A, Harrington EA, Evan GI: Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359:554, 1992
    • (1992) Nature , vol.359 , pp. 554
    • Fanidi, A.1    Harrington, E.A.2    Evan, G.I.3
  • 56
    • 0028263811 scopus 로고
    • c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington EA, Bennet MR, Fanidi A, Evan GI: c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 13:3286, 1994
    • (1994) EMBO J , vol.13 , pp. 3286
    • Harrington, E.A.1    Bennet, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 57
    • 0026669469 scopus 로고
    • p53 function and dysfunction
    • Vogelstein B, Kinzler KW: p53 function and dysfunction. Cell 70:523, 1992
    • (1992) Cell , vol.70 , pp. 523
    • Vogelstein, B.1    Kinzler, K.W.2
  • 61
    • 0028171968 scopus 로고
    • Mediation of c-myc-induced apoptosis by p53
    • Hermeking H, Eick D: Mediation of c-myc-induced apoptosis by p53. Science 265:2091, 1994
    • (1994) Science , vol.265 , pp. 2091
    • Hermeking, H.1    Eick, D.2
  • 64
    • 0027333347 scopus 로고
    • Programmed cell death, apoptosis and killer genes
    • Schwartz LM, Osborne BA: Programmed cell death, apoptosis and killer genes. Immunol Today 14:582, 1993
    • (1993) Immunol Today , vol.14 , pp. 582
    • Schwartz, L.M.1    Osborne, B.A.2
  • 65
    • 0029591322 scopus 로고
    • Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia
    • Binet JL, Mentz F, Leblond V, Merle-Béral H: Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia. Leukemia 9:2159, 1995
    • (1995) Leukemia , vol.9 , pp. 2159
    • Binet, J.L.1    Mentz, F.2    Leblond, V.3    Merle-Béral, H.4


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