-
1
-
-
0025251664
-
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2
-
Strasser A., Harris A.W., Bath M.L., Cory S. Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature. 348:1990;331-333.
-
(1990)
Nature
, vol.348
, pp. 331-333
-
-
Strasser, A.1
Harris, A.W.2
Bath, M.L.3
Cory, S.4
-
2
-
-
0030665659
-
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
-
Strasser A., Huang D.C.S., Vaux D.L. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochem Biophys Acta. 1333:1997;F151-F178.
-
(1997)
Biochem Biophys Acta
, vol.1333
, pp. 151-F178
-
-
Strasser, A.1
Huang, D.C.S.2
Vaux, D.L.3
-
3
-
-
0025939204
-
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
-
Strasser A., Whittingham S., Vaux D.L., Bath M.L., Adams J.M., Cory S., Harris A.W. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sci USA. 88:1991;8661-8665.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8661-8665
-
-
Strasser, A.1
Whittingham, S.2
Vaux, D.L.3
Bath, M.L.4
Adams, J.M.5
Cory, S.6
Harris, A.W.7
-
4
-
-
0033007598
-
Apoptosis and autoimmune disease
-
O'Reilly L.A., Strasser A. Apoptosis and autoimmune disease. Inflamm Res. 48:1999;5-21.
-
(1999)
Inflamm Res
, vol.48
, pp. 5-21
-
-
O'Reilly, L.A.1
Strasser, A.2
-
5
-
-
0028212937
-
Apoptosis and its role in human disease
-
Barr P.J., Tomei L.D. Apoptosis and its role in human disease. Biotechnology. 12:1994;487-493.
-
(1994)
Biotechnology
, vol.12
, pp. 487-493
-
-
Barr, P.J.1
Tomei, L.D.2
-
6
-
-
0032575705
-
A matter of life and cell death
-
Evan G., Littlewood T. A matter of life and cell death. Science. 281:1998;1317-1321.
-
(1998)
Science
, vol.281
, pp. 1317-1321
-
-
Evan, G.1
Littlewood, T.2
-
7
-
-
0030669560
-
Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice
-
Jäger R., Herzer U., Schenkel J., Weiher H. Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice. Oncogene. 15:1997;1787-1795.
-
(1997)
Oncogene
, vol.15
, pp. 1787-1795
-
-
Jäger, R.1
Herzer, U.2
Schenkel, J.3
Weiher, H.4
-
8
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr C.J., Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1999;1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
9
-
-
0033597816
-
Evolving ideas about cyclins
-
Roberts J.M. Evolving ideas about cyclins. Cell. 98:1999;129-132.
-
(1999)
Cell
, vol.98
, pp. 129-132
-
-
Roberts, J.M.1
-
10
-
-
0033602410
-
Balancing proliferation and apoptosis in vivo: The Goldilocks theory of E2F/DP action
-
Yamasaki L. Balancing proliferation and apoptosis in vivo: the Goldilocks theory of E2F/DP action. Biochem Biophys Acta. 1423:1999;M9-M15.
-
(1999)
Biochem Biophys Acta
, vol.1423
, pp. 9-M15
-
-
Yamasaki, L.1
-
11
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen G.S., Dixit V.M. Caspases: intracellular signaling by proteolysis. Cell. 91:1997;443-446.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
12
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
13
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Shows that the WD40 repeat region of the adaptor protein Apaf-1 mediates its activation by cytochrome c and dATP. Apaf-1 lacking this region is a constitutive activator of caspase 9
-
Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., Alnemri E.S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol Cell. 1:1998;949-957. Shows that the WD40 repeat region of the adaptor protein Apaf-1 mediates its activation by cytochrome c and dATP. Apaf-1 lacking this region is a constitutive activator of caspase 9.
-
(1998)
Mol Cell
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
14
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
Reports that enforced dimerisation of procaspase 8 is sufficient to cause apoptosis, and that a mutant form of caspase 8, which cannot be processed, nevertheless retains proteolytic activity, suggesting that aggregation alone can result in caspase autoactivation
-
Muzio M., Stockwell B.R., Stennicke H.R., Salvesen G.S., Dixit V.M. An induced proximity model for caspase-8 activation. J Biol Chem. 273:1998;2926-2930. Reports that enforced dimerisation of procaspase 8 is sufficient to cause apoptosis, and that a mutant form of caspase 8, which cannot be processed, nevertheless retains proteolytic activity, suggesting that aggregation alone can result in caspase autoactivation.
-
(1998)
J Biol Chem
, vol.273
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
15
-
-
0032548842
-
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHa1) death signal
-
•] that aggregation alone can result in caspase autoactivation
-
•] that aggregation alone can result in caspase autoactivation.
-
(1998)
J Biol Chem
, vol.273
, pp. 4345-4349
-
-
Martin, D.A.1
Siegel, R.M.2
Zheng, L.3
Lenardo, M.J.4
-
16
-
-
0029834497
-
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease
-
Smith K.G.C., Strasser A., Vaux D.L. CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease. EMBO J. 15:1996;5167-5176.
-
(1996)
EMBO J
, vol.15
, pp. 5167-5176
-
-
Smith, K.G.C.1
Strasser, A.2
Vaux, D.L.3
-
17
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Describes the caspase 8 knockout in mice. Cells from these animals are resistant to apoptosis triggered through death receptors
-
Varfolomeev E.E., Schuchmann M., Luria V., Chiannilkulchai N., Beckmann J.S., Mett I.L., Rebrikov D., Brodianski V.M., Kemper O.C., Kollet O.et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9:1998;267-276. Describes the caspase 8 knockout in mice. Cells from these animals are resistant to apoptosis triggered through death receptors.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
-
18
-
-
0032472916
-
A dominant interfering mutant of FADD/Mort1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Shows that lymphocytes from mice expressing a dominant negative form of FADD were resistant to death triggered through death receptors. Surprisingly, these cells also have a defect in proliferation
-
Newton K., Harris A.W., Bath M.L., Smith K.G.C., Strasser A. A dominant interfering mutant of FADD/Mort1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 17:1998;706-718. Shows that lymphocytes from mice expressing a dominant negative form of FADD were resistant to death triggered through death receptors. Surprisingly, these cells also have a defect in proliferation.
-
(1998)
EMBO J
, vol.17
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.C.4
Strasser, A.5
-
19
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Shows that FADD deficient embryonic fibroblasts are resistant to death triggered through most death receptors, but sensitive to apoptosis induced by ligation of DR4 and treatment with other apoptotic stimuli
-
Yeh W.C., Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., Ng M., Wakeham A., Khoo W., Mitchell K.et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science. 279:1998;1954-1958. Shows that FADD deficient embryonic fibroblasts are resistant to death triggered through most death receptors, but sensitive to apoptosis induced by ligation of DR4 and treatment with other apoptotic stimuli.
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
Ng, M.7
Wakeham, A.8
Khoo, W.9
Mitchell, K.10
-
20
-
-
0032546387
-
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Demonstrates that FADD knockout mice die in utero, and that cells from these mice are resistant to death triggered through death receptors. FADD-deficient T lymphocytes from the same mice also had a defect in proliferation, confirming the role of FADD in proliferation
-
Zhang J., Cado D., Chen A., Kabra N.H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature. 392:1998;296-300. Demonstrates that FADD knockout mice die in utero, and that cells from these mice are resistant to death triggered through death receptors. FADD-deficient T lymphocytes from the same mice also had a defect in proliferation, confirming the role of FADD in proliferation.
-
(1998)
Nature
, vol.392
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
21
-
-
0029609086
-
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
-
Strasser A., Harris A.W., Huang D.C.S., Krammer P.H., Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14:1995;6136-6147.
-
(1995)
EMBO J
, vol.14
, pp. 6136-6147
-
-
Strasser, A.1
Harris, A.W.2
Huang, D.C.S.3
Krammer, P.H.4
Cory, S.5
-
22
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
••]
-
••].
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.-Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.7
Rakic, P.8
Flavell, R.A.9
-
23
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
••] describe studies of cells from caspase 9 knockout mice. These cells exhibit defects in apoptosis and effector caspase activation, triggered through a variety of stimuli but are normally sensitive to death receptor-induced apoptosis
-
••] describe studies of cells from caspase 9 knockout mice. These cells exhibit defects in apoptosis and effector caspase activation, triggered through a variety of stimuli but are normally sensitive to death receptor-induced apoptosis.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
-
25
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
••] the authors describe studies using Apaf-1 knockout mice. Cells from these mice exhibit defects in apoptosis, triggered through a variety of means, but have normal responses to apoptotic stimuli delivered through death receptors
-
••] the authors describe studies using Apaf-1 knockout mice. Cells from these mice exhibit defects in apoptosis, triggered through a variety of means, but have normal responses to apoptotic stimuli delivered through death receptors.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.-Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
26
-
-
0025751550
-
Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
-
Sentman C.L., Shutter J.R., Hockenbery D., Kanagawa O., Korsmeyer S.J. Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell. 67:1991;879-888.
-
(1991)
Cell
, vol.67
, pp. 879-888
-
-
Sentman, C.L.1
Shutter, J.R.2
Hockenbery, D.3
Kanagawa, O.4
Korsmeyer, S.J.5
-
27
-
-
0025786164
-
Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
-
Strasser A., Harris A.W., Cory S. Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell. 67:1991;889-899.
-
(1991)
Cell
, vol.67
, pp. 889-899
-
-
Strasser, A.1
Harris, A.W.2
Cory, S.3
-
28
-
-
0031945458
-
Cell cycle regulation and apoptosis
-
King K.L., Cidlowski J.A. Cell cycle regulation and apoptosis. Annu Rev Physiol. 60:1998;601-617.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 601-617
-
-
King, K.L.1
Cidlowski, J.A.2
-
30
-
-
0029671430
-
Cdc2-dependent kinase activity during apoptosis: A possible mechanism of DNase1 leading to DNA breakdown
-
Cdc2-dependent kinase activity during apoptosis: a possible mechanism of DNase1 leading to DNA breakdown. Eur J Cell Biol. 69:1996;143-150.
-
(1996)
Eur J Cell Biol
, vol.69
, pp. 143-150
-
-
Schroeter, M.1
Peitsch, M.C.2
Tschopp, J.3
-
31
-
-
0033559980
-
The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis
-
Hakem A., Sasaki T., Kozieradzki I., Penninger J.M. The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis. J Exp Med. 89:1999;957-968.
-
(1999)
J Exp Med
, vol.89
, pp. 957-968
-
-
Hakem, A.1
Sasaki, T.2
Kozieradzki, I.3
Penninger, J.M.4
-
32
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
33
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A., McDonnell J.M., Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13:1999;1899-1911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
34
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping I.S., Gross A., Lavoie J.N., Nguyen M., Jemmerson R., Roth K., Korsmeyer S.J., Shore G.C. Regulated targeting of BAX to mitochondria. J Cell Biol. 143:1998;207-215.
-
(1998)
J Cell Biol
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
35
-
-
0029807585
-
BID: A novel BH3 domain-only death agonist
-
Wang K., Yin X-M., Chao D.T., Milliman C.L., Korsmeyer S.J. BID: a novel BH3 domain-only death agonist. Genes Dev. 10:1996;2859-2869.
-
(1996)
Genes Dev
, vol.10
, pp. 2859-2869
-
-
Wang, K.1
Yin, X.-M.2
Chao, D.T.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
37
-
-
0033104996
-
The pro-apoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
Showed that the pro-apoptotic Bcl-2 family member Bim is sequestered by components of the dynein motor complex, and is released by apoptotic stimuli
-
Puthalakath H., Huang D.C.S., O'Reilly L.A., King S.M., Strasser A. The pro-apoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell. 3:1999;287-296. Showed that the pro-apoptotic Bcl-2 family member Bim is sequestered by components of the dynein motor complex, and is released by apoptotic stimuli.
-
(1999)
Mol Cell
, vol.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.S.2
O'Reilly, L.A.3
King, S.M.4
Strasser, A.5
-
38
-
-
0026480579
-
Ultrastructural localization of BCL-2 protein
-
Monaghan P., Robertson D., Amos T.A.S., Dyer M.J.S., Mason D.Y., Greaves M.F. Ultrastructural localization of BCL-2 protein. J Histochem Cytochem. 40:1992;1819-1825.
-
(1992)
J Histochem Cytochem
, vol.40
, pp. 1819-1825
-
-
Monaghan, P.1
Robertson, D.2
Amos, T.A.S.3
Dyer, M.J.S.4
Mason, D.Y.5
Greaves, M.F.6
-
39
-
-
0027977928
-
The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum and the outer mitochondrial membrane
-
Lithgow T., van Driel R., Bertram J.F., Strasser A. The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum and the outer mitochondrial membrane. Cell Growth Differ. 5:1994;411-417.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 411-417
-
-
Lithgow, T.1
Van Driel, R.2
Bertram, J.F.3
Strasser, A.4
-
40
-
-
0033579810
-
Mitochondrial release of caspase-2 and -9 during the apoptotic process
-
The authors show that procaspase 2 and procaspase 9 are located inside mitochondria in healthy cells, but are released into the cytosol, where they are activated, following apoptotic stimuli
-
Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Brenner C., Larochette N., Prevost M-C., Alzari P.M., Kroemer G. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J Exp Med. 189:1999;381-394. The authors show that procaspase 2 and procaspase 9 are located inside mitochondria in healthy cells, but are released into the cytosol, where they are activated, following apoptotic stimuli.
-
(1999)
J Exp Med
, vol.189
, pp. 381-394
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Brenner, C.5
Larochette, N.6
Prevost, M.-C.7
Alzari, P.M.8
Kroemer, G.9
-
41
-
-
0032799633
-
Caspases: Their intracellular localization and translocation during apoptosis
-
Shows that procaspases are selectively localised in intracellular components. This confirms and extends the idea that caspase activation follows subcellular redistribution
-
Zhivotovsky B., Samali A., Gahm A., Orrenius S. Caspases: their intracellular localization and translocation during apoptosis. Cell Death Differ. 6:1999;644-651. Shows that procaspases are selectively localised in intracellular components. This confirms and extends the idea that caspase activation follows subcellular redistribution.
-
(1999)
Cell Death Differ
, vol.6
, pp. 644-651
-
-
Zhivotovsky, B.1
Samali, A.2
Gahm, A.3
Orrenius, S.4
-
42
-
-
0028281026
-
Bcl-2 protein localizes to the chromosomes of mitotic nuclei and is correlated with the cell cycle in cultured epithelial cell lines
-
Lu Q-L., Hanby A.M., Hajibagheri M.A.N., Gschmeissner S.E., Lu P-J., Taylor-Papadimitriou J., Krajewski S., Reed J.C., Wright N.A. Bcl-2 protein localizes to the chromosomes of mitotic nuclei and is correlated with the cell cycle in cultured epithelial cell lines. J Cell Sci. 107:1994;363-371.
-
(1994)
J Cell Sci
, vol.107
, pp. 363-371
-
-
Lu, Q.-L.1
Hanby, A.M.2
Hajibagheri, M.A.N.3
Gschmeissner, S.E.4
Lu, P.-J.5
Taylor-Papadimitriou, J.6
Krajewski, S.7
Reed, J.C.8
Wright, N.A.9
-
43
-
-
0028793408
-
Nuclear and cytoplasmic bcl-2 expression in endometrial hyperplasia and adenocarcinoma
-
Chan W.K., Mole M.M., Levison D.A., Ball R.Y., Lu Q-L., Patel K., Hanby A.M. Nuclear and cytoplasmic bcl-2 expression in endometrial hyperplasia and adenocarcinoma. J Pathol. 177:1995;241-246.
-
(1995)
J Pathol
, vol.177
, pp. 241-246
-
-
Chan, W.K.1
Mole, M.M.2
Levison, D.A.3
Ball, R.Y.4
Lu, Q.-L.5
Patel, K.6
Hanby, A.M.7
-
44
-
-
0028207925
-
Transient mitotic phase localization of Bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis
-
Willingham M.C., Bhalla K. Transient mitotic phase localization of Bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis. J Histochem Cytochem. 42:1994;441-450.
-
(1994)
J Histochem Cytochem
, vol.42
, pp. 441-450
-
-
Willingham, M.C.1
Bhalla, K.2
-
45
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin X-Q., Livingston D.M., Kaelin J. Jr., Adams P.D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci USA. 91:1994;10918-10922.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.-Q.1
Livingston, D.M.2
Kaelin, J.3
Adams, P.D.4
-
46
-
-
0031923282
-
Coupling of cell growth control and apoptosis functions of Id proteins
-
Norton J.D., Atherton G.T. Coupling of cell growth control and apoptosis functions of Id proteins. Mol Cell Biol. 18:1998;2371-2381.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2371-2381
-
-
Norton, J.D.1
Atherton, G.T.2
-
47
-
-
0030198199
-
TGFβ1 inhibits NF-κB/rel activity inducing apoptosis of B cells: Transcriptional activation of IκBα
-
Arsura M., Wu M., Sonenshein G.E. TGFβ1 inhibits NF-κB/rel activity inducing apoptosis of B cells: transcriptional activation of IκBα Immunity. 5:1996;31-40.
-
(1996)
Immunity
, vol.5
, pp. 31-40
-
-
Arsura, M.1
Wu, M.2
Sonenshein, G.E.3
-
48
-
-
0028171968
-
Mediation of c-Myc-induced apoptosis by p53
-
Hermeking H., Eick D. Mediation of c-Myc-induced apoptosis by p53. Science. 265:1994;2091-2093.
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
49
-
-
0029803667
-
Myc and Max homologs in Drosophila
-
Gallant P., Shiio Y., Cheng P.F., Parkhurst S.M., Eisenman R.N. Myc and Max homologs in Drosophila. Science. 274:1996;1523-1527.
-
(1996)
Science
, vol.274
, pp. 1523-1527
-
-
Gallant, P.1
Shiio, Y.2
Cheng, P.F.3
Parkhurst, S.M.4
Eisenman, R.N.5
-
50
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone L.R., White A., Sprouse J., Livanos E., Jacks T., Tlsty T.D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell. 70:1992;923-935.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
White, A.2
Sprouse, J.3
Livanos, E.4
Jacks, T.5
Tlsty, T.D.6
-
51
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
Yin Y., Tainsky M.A., Bischoff F.Z., Strong L.C., Wahl G.M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell. 70:1992;937-948.
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
-
52
-
-
0027319521
-
P53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe S.W., Schmitt E.M., Smith S.W., Osborne B.A., Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 362:1993;847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
53
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke A.R., Purdie C.A., Harrison D.J., Morris R.G., Bird C.C., Hooper M.L., Wyllie A.H. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 362:1993;849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
54
-
-
0028072523
-
DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
-
Strasser A., Harris A.W., Jacks T., Cory S. DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell. 79:1994;329-339.
-
(1994)
Cell
, vol.79
, pp. 329-339
-
-
Strasser, A.1
Harris, A.W.2
Jacks, T.3
Cory, S.4
-
55
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J., Chandrasekaran C., Gordon J.I., Beach D., Jacks T., Hannon G.J. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature. 377:1995;552-557.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
56
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Showed that apoptosis triggered by p53 activation is transduced by Apaf-1 and caspase 9, demonstrating the antitumour potential of members of the apoptotic effector machinery
-
Soengas M.S., Alarcón R.M., Yoshida H., Giaccia A.J., Hakem R., Mak T.W., Lowe S.W. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science. 284:1999;156-159. Showed that apoptosis triggered by p53 activation is transduced by Apaf-1 and caspase 9, demonstrating the antitumour potential of members of the apoptotic effector machinery.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcón, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
57
-
-
0022385213
-
Activation of mouse lymphocytes inhibits induction of rapid cell death by X-irradiation
-
Lowenthal J.W., Harris A.W. Activation of mouse lymphocytes inhibits induction of rapid cell death by X-irradiation. J Immunol. 135:1985;1119-1125.
-
(1985)
J Immunol
, vol.135
, pp. 1119-1125
-
-
Lowenthal, J.W.1
Harris, A.W.2
-
58
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi L.D., Lowe S.W., Brugarolas J., Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J. 15:1996;3693-3701.
-
(1996)
EMBO J
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
59
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
60
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
Knudson C.M., Tung K.S.K., Tourtellotte W.G., Brown G.A.J., Korsmeyer S.J. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science. 270:1995;96-99.
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.K.2
Tourtellotte, W.G.3
Brown, G.A.J.4
Korsmeyer, S.J.5
-
61
-
-
0029669929
-
T cells from baxa transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53
-
Brady H.J.M., Salomns G.S., Bobeldijk R.C., Berns A.J.M. T cells from baxa transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53. EMBO J. 15:1996;1221-1230.
-
(1996)
EMBO J
, vol.15
, pp. 1221-1230
-
-
Brady, H.J.M.1
Salomns, G.S.2
Bobeldijk, R.C.3
Berns, A.J.M.4
-
62
-
-
0030889549
-
Differentiation induced by RB expression and apoptosis induced by p53 expression in an osteosarcoma cell line
-
Ookawa K., Tsuchida S., Adachi J-I., Yokota J. Differentiation induced by RB expression and apoptosis induced by p53 expression in an osteosarcoma cell line. Oncogene. 14:1997;1389-1396.
-
(1997)
Oncogene
, vol.14
, pp. 1389-1396
-
-
Ookawa, K.1
Tsuchida, S.2
Adachi, J.-I.3
Yokota, J.4
-
63
-
-
0032159103
-
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
-
Tsai K.Y., Hu Y., Macleod K.F., Crowley D., Yamasaki L., Jacks T. Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol Cell. 2:1998;293-304.
-
(1998)
Mol Cell
, vol.2
, pp. 293-304
-
-
Tsai, K.Y.1
Hu, Y.2
Macleod, K.F.3
Crowley, D.4
Yamasaki, L.5
Jacks, T.6
-
64
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T., Fazeli A., Schmitt E.M., Bronson R.T., Goodell M.A., Weinberg R.A. Effects of an Rb mutation in the mouse. Nature. 359:1992;295-300.
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
65
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke A.R., Maandag E.R., van Roon M., van der Lugt N.M., van der Valk M., Hooper M.L., Berns A., te Riele H. Requirement for a functional Rb-1 gene in murine development. Nature. 359:1992;328-330.
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
Van Roon, M.3
Van Der Lugt, N.M.4
Van Der Valk, M.5
Hooper, M.L.6
Berns, A.7
Te Riele, H.8
-
66
-
-
0029910628
-
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
-
Macleod K.F., Hu Y., Jacks T. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15:1996;6178-6188.
-
(1996)
EMBO J
, vol.15
, pp. 6178-6188
-
-
Macleod, K.F.1
Hu, Y.2
Jacks, T.3
-
68
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell. 89:1997;1033-1041.
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
Von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
69
-
-
0030787787
-
Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice
-
Kondo M., Akashi K., Domen J., Sugamura K., Weissman I.L. Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice. Immunity. 7:1997;155-162.
-
(1997)
Immunity
, vol.7
, pp. 155-162
-
-
Kondo, M.1
Akashi, K.2
Domen, J.3
Sugamura, K.4
Weissman, I.L.5
-
70
-
-
0031715301
-
Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in interleukin-7 receptor-deficient mice but can enhance survival of mature B cells
-
Maraskovsky E., Peschon J.J., McKenna H., Teepe M., Strasser A. Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in interleukin-7 receptor-deficient mice but can enhance survival of mature B cells. Int Immunol. 10:1998;1367-1375.
-
(1998)
Int Immunol
, vol.10
, pp. 1367-1375
-
-
Maraskovsky, E.1
Peschon, J.J.2
McKenna, H.3
Teepe, M.4
Strasser, A.5
-
71
-
-
0030046753
-
STATs: Signal transducers and activators of transcription
-
Ihle J.N. STATs: Signal transducers and activators of transcription. Cell. 84:1996;331-334.
-
(1996)
Cell
, vol.84
, pp. 331-334
-
-
Ihle, J.N.1
-
72
-
-
0033199236
-
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
-
Nosaka T., Kawashima T., Misawa K., Ikuta K., Mui A.L-F., Kitamura T. STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J. 18:1999;4754-4765.
-
(1999)
EMBO J
, vol.18
, pp. 4754-4765
-
-
Nosaka, T.1
Kawashima, T.2
Misawa, K.3
Ikuta, K.4
Mui, A.L.-F.5
Kitamura, T.6
-
73
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
Teglund S., McKay C., Schuetz E., van Deursen J.M., Stravopodis D., Wang D., Brown M., Bodner S., Grosveld G., Ihle J.N. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 93:1998;841-850.
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
McKay, C.2
Schuetz, E.3
Van Deursen, J.M.4
Stravopodis, D.5
Wang, D.6
Brown, M.7
Bodner, S.8
Grosveld, G.9
Ihle, J.N.10
-
74
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
-
Thomis D.C., Gurniak C.B., Tivol E., Sharpe A.H., Berg L.J. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science. 270:1995;794-797.
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.C.1
Gurniak, C.B.2
Tivol, E.3
Sharpe, A.H.4
Berg, L.J.5
-
75
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka T., van Deursen J.M., Tripp R.A., Thierfelder W.E., Witthuhn B.A., McMickle A.P., Doherty P.C., Grosveld G.C., Ihle J.N. Defective lymphoid development in mice lacking Jak3. Science. 270:1995;800-802.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
Van Deursen, J.M.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
Doherty, P.C.7
Grosveld, G.C.8
Ihle, J.N.9
-
76
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
77
-
-
0032473405
-
B lymphocytes differentially use the Rel and nuclear factor kB1 (NF-kB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells
-
Grumont R.J., Rourke I.J., O'Reilly L.A., Strasser A., Miyake K., Sha W., Gerondakis S. B lymphocytes differentially use the Rel and nuclear factor kB1 (NF-kB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J Exp Med. 187:1998;663-674.
-
(1998)
J Exp Med
, vol.187
, pp. 663-674
-
-
Grumont, R.J.1
Rourke, I.J.2
O'Reilly, L.A.3
Strasser, A.4
Miyake, K.5
Sha, W.6
Gerondakis, S.7
-
78
-
-
0033557805
-
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
-
Showed that c-Rel directly induces transcription of the anti-apoptotic Bcl-2 family member A1 in response to mitogenic stimulation
-
Grumont R.J., Rourke I.J., Gerondakis S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev. 13:1999;400-411. Showed that c-Rel directly induces transcription of the anti-apoptotic Bcl-2 family member A1 in response to mitogenic stimulation.
-
(1999)
Genes Dev
, vol.13
, pp. 400-411
-
-
Grumont, R.J.1
Rourke, I.J.2
Gerondakis, S.3
-
79
-
-
0029150389
-
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
-
Köntgen F., Grumont R.J., Strasser A., Metcalf D., Li R., Tarlinton D., Gerondakis S. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1995;1965-1977.
-
(1995)
Genes Dev
, vol.9
, pp. 1965-1977
-
-
Köntgen, F.1
Grumont, R.J.2
Strasser, A.3
Metcalf, D.4
Li, R.5
Tarlinton, D.6
Gerondakis, S.7
-
80
-
-
0033534465
-
Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kB
-
Kasibhatla S., Genestier L., Green D.R. Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kB. J Biol Chem. 274:1999;987-992.
-
(1999)
J Biol Chem
, vol.274
, pp. 987-992
-
-
Kasibhatla, S.1
Genestier, L.2
Green, D.R.3
-
81
-
-
0028909197
-
Fas ligand mediates activation-induced cell death in human T lymphocytes
-
Alderson M.R., Tough T.W., Davis-Smith T., Braddy S., Falk B., Schooley K.A., Goodwin R.G., Smith C.A., Ramsdell F., Lynch D.H. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med. 181:1995;71-77.
-
(1995)
J Exp Med
, vol.181
, pp. 71-77
-
-
Alderson, M.R.1
Tough, T.W.2
Davis-Smith, T.3
Braddy, S.4
Falk, B.5
Schooley, K.A.6
Goodwin, R.G.7
Smith, C.A.8
Ramsdell, F.9
Lynch, D.H.10
-
82
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kB
-
Beg A.A., Sha W.C., Bronson R.T., Ghosh S., Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kB. Nature. 376:1995;167-170.
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
83
-
-
0032980504
-
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality
-
Doi T.S., Marino M.W., Takahashi T., Yoshida T., Sakakura T., Old L.J., Obata Y. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc Natl Acad Sci USA. 96:1999;2994-2999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2994-2999
-
-
Doi, T.S.1
Marino, M.W.2
Takahashi, T.3
Yoshida, T.4
Sakakura, T.5
Old, L.J.6
Obata, Y.7
-
84
-
-
0030476922
-
The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry
-
O'Reilly L.A., Huang D.C.S., Strasser A. The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J. 15:1996;6979-6990.
-
(1996)
EMBO J
, vol.15
, pp. 6979-6990
-
-
O'Reilly, L.A.1
Huang, D.C.S.2
Strasser, A.3
-
85
-
-
0029843941
-
Cross-talk between cell death and cell cycle progression: Bcl-2 regulates NFAT-mediated activation
-
Linette G.P., Li Y., Roth K., Korsmeyer S.J. Cross-talk between cell death and cell cycle progression: Bcl-2 regulates NFAT-mediated activation. Proc Natl Acad Sci USA. 93:1996;9545-9552.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9545-9552
-
-
Linette, G.P.1
Li, Y.2
Roth, K.3
Korsmeyer, S.J.4
-
86
-
-
0029938724
-
Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death
-
Mazel S., Burtrum D., Petrie H.T. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J Exp Med. 183:1996;2219-2226.
-
(1996)
J Exp Med
, vol.183
, pp. 2219-2226
-
-
Mazel, S.1
Burtrum, D.2
Petrie, H.T.3
-
87
-
-
0030794452
-
The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
-
Huang D.C.S., O'Reilly L.A., Strasser A., Cory S. The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J. 16:1997;4628-4638.
-
(1997)
EMBO J
, vol.16
, pp. 4628-4638
-
-
Huang, D.C.S.1
O'Reilly, L.A.2
Strasser, A.3
Cory, S.4
-
88
-
-
0032520006
-
BCL-2 expression correlates with lower proliferative activity in the intermediate- And high-grade non-Hodgkin's lymphomas: An Eastern Cooperative Oncology Group and Southwest Oncology Group cooperative laboratory study
-
Winter J.N., Andersen J., Reed J.C., Krajewski S., Variakojis D., Bauer K.D., Fisher R.I., Gordon L.I., Oken M.M., Jiang S.W.et al. BCL-2 expression correlates with lower proliferative activity in the intermediate- and high-grade non-Hodgkin's lymphomas: an Eastern Cooperative Oncology Group and Southwest Oncology Group cooperative laboratory study. Blood. 91:1998;1391-1398.
-
(1998)
Blood
, vol.91
, pp. 1391-1398
-
-
Winter, J.N.1
Andersen, J.2
Reed, J.C.3
Krajewski, S.4
Variakojis, D.5
Bauer, K.D.6
Fisher, R.I.7
Gordon, L.I.8
Oken, M.M.9
Jiang, S.W.10
-
89
-
-
0027537461
-
An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
-
Crook N.E., Clem R.J., Miller L.K. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J Virol. 67:1993;2168-2174.
-
(1993)
J Virol
, vol.67
, pp. 2168-2174
-
-
Crook, N.E.1
Clem, R.J.2
Miller, L.K.3
-
90
-
-
0030447149
-
Inhibition of interleukin 1b-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP
-
Hawkins C.J., Uren A.G., Häcker G., Medcalf R.L., Vaux D.L. Inhibition of interleukin 1b-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP. Proc Natl Acad Sci USA. 93:1996;13786-13790.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13786-13790
-
-
Hawkins, C.J.1
Uren, A.G.2
Häcker, G.3
Medcalf, R.L.4
Vaux, D.L.5
-
91
-
-
15844425961
-
A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors
-
Duckett C.S., Nava V.E., Gedrich R.W., Clem R.J., Van Dongen J.L., Gilfillan M.C., Shiels H., Hardwick J.M., Thompson C.B. A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors. EMBO J. 15:1996;2685-2694.
-
(1996)
EMBO J
, vol.15
, pp. 2685-2694
-
-
Duckett, C.S.1
Nava, V.E.2
Gedrich, R.W.3
Clem, R.J.4
Van Dongen, J.L.5
Gilfillan, M.C.6
Shiels, H.7
Hardwick, J.M.8
Thompson, C.B.9
-
92
-
-
0029583176
-
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
-
Hay B.A., Wassarman D.A., Rubin G.M. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell. 83:1995;1253-1262.
-
(1995)
Cell
, vol.83
, pp. 1253-1262
-
-
Hay, B.A.1
Wassarman, D.A.2
Rubin, G.M.3
-
93
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., Farahani R., McLean M., Ikeda J.E., MacKenzie A., Korneluk R.G. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature. 379:1996;349-353.
-
(1996)
Nature
, vol.379
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
Lefebvre, C.4
Baird, S.5
Cherton-Horvat, G.6
Farahani, R.7
McLean, M.8
Ikeda, J.E.9
MacKenzie, A.10
Korneluk, R.G.11
-
94
-
-
0033588273
-
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
-
Wang S.L., Hawkins C.J., Yoo S.J., Müller H-A.J., Hay B.A. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell. 98:1999;453-463.
-
(1999)
Cell
, vol.98
, pp. 453-463
-
-
Wang, S.L.1
Hawkins, C.J.2
Yoo, S.J.3
Müller, H.-A.J.4
Hay, B.A.5
-
95
-
-
0033621107
-
Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division
-
Shows that yeast homologues of the mammalian IAP proteins are involved in regulation of cell division, suggesting that many mammalian IAPs may have a role in controlling proliferation, rather than apoptosis
-
Uren A.G., Beilharz T., O'Connell M.J., Bugg S.J., van Driel R., Vaux D.L., Lithgow T. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division. Proc Natl Acad Sci USA. 96:1999;10170-10175. Shows that yeast homologues of the mammalian IAP proteins are involved in regulation of cell division, suggesting that many mammalian IAPs may have a role in controlling proliferation, rather than apoptosis.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10170-10175
-
-
Uren, A.G.1
Beilharz, T.2
O'Connell, M.J.3
Bugg, S.J.4
Van Driel, R.5
Vaux, D.L.6
Lithgow, T.7
|