메뉴 건너뛰기




Volumn 59, Issue 1, 2000, Pages 47-53

Expression of hypoxia-inducible factor 1: Mechanisms and consequences

Author keywords

Angiogenesis; Cancer; Ischemia; Oxygen homeostasis; Pulmonary hypertension

Indexed keywords

HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR;

EID: 0033991530     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00292-0     Document Type: Conference Paper
Times cited : (464)

References (51)
  • 1
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza G.L., Wang G.L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol. 12:1992;5447-5454.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 2
    • 0027210562 scopus 로고
    • General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
    • Wang G.L., Semenza G.L. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA. 90:1993;4304-4308.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 4
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang G.L., Semenza G.L. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem. 270:1995;1230-1237.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 6
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang B.-H., Rue E., Wang G.L., Roe R., Semenza G.L. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem. 271:1996;17771-17778.
    • (1996) J Biol Chem , vol.271 , pp. 17771-17778
    • Jiang, B.-H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 7
    • 0030460724 scopus 로고    scopus 로고
    • Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
    • Semenza G.L., Jiang B.-H., Leung S.W., Passantino R., Concordet J.-P., Maire P., Giallongo A. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem. 271:1996;32529-32537.
    • (1996) J Biol Chem , vol.271 , pp. 32529-32537
    • Semenza, G.L.1    Jiang, B.-H.2    Leung, S.W.3    Passantino, R.4    Concordet, J.-P.5    Maire, P.6    Giallongo, A.7
  • 10
    • 0031753986 scopus 로고    scopus 로고
    • Temporal, spatial and oxygen-regulated expression of hypoxia-inducible factor 1 in the lung
    • Yu A.Y., Frid M.G., Shimoda L.A., Wiener C.M., Stenmark K., Semenza G.L. Temporal, spatial and oxygen-regulated expression of hypoxia-inducible factor 1 in the lung. Am J Physiol. 275:1998;L818-L826.
    • (1998) Am J Physiol , vol.275
    • Yu, A.Y.1    Frid, M.G.2    Shimoda, L.A.3    Wiener, C.M.4    Stenmark, K.5    Semenza, G.L.6
  • 11
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
    • Huang L.E., Arany Z., Livingston D.M., Bunn H.F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J Biol Chem. 271:1996;32253-32259.
    • (1996) J Biol Chem , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 13
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway
    • Kallio P.J., Wilson W.J., O'Brien S., Makino Y., Poellinger L. Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway. J Biol Chem. 274:1999;6519-6525.
    • (1999) J Biol Chem , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 14
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions: Its stabilization by hypoxia depends upon redox-induced changes
    • Salceda S., Caro J. Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions Its stabilization by hypoxia depends upon redox-induced changes . J Biol Chem. 272:1997;22642-22647.
    • (1997) J Biol Chem , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 15
    • 0030787469 scopus 로고    scopus 로고
    • Transactivation and inhibitory domains of hypoxia-inducible factor 1α: Modulation of transcriptional activity by oxygen tension
    • Jiang B.-H., Zheng J.Z., Leung S.W., Roe R., Semenza G.L. Transactivation and inhibitory domains of hypoxia-inducible factor 1α Modulation of transcriptional activity by oxygen tension . J Biol Chem. 272:1997;19253-19260.
    • (1997) J Biol Chem , vol.272 , pp. 19253-19260
    • Jiang, B.-H.1    Zheng, J.Z.2    Leung, S.W.3    Roe, R.4    Semenza, G.L.5
  • 16
    • 0030937718 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the α subunit
    • Pugh C.W., O'Rourke J.F., Nagao M., Gleadle J.M., Ratcliffe P.J. Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the α subunit. J Biol Chem. 272:1997;11205-11214.
    • (1997) J Biol Chem , vol.272 , pp. 11205-11214
    • Pugh, C.W.1    O'Rourke, J.F.2    Nagao, M.3    Gleadle, J.M.4    Ratcliffe, P.J.5
  • 17
    • 0033118983 scopus 로고    scopus 로고
    • Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
    • Ema M., Hirota K., Mimura J., Abe H., Yodoi J., Sogawa K., Poellinger L., Fujii-Kuriyama Y. Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia Their stabilization and redox signal-induced interaction with CBP/p300 . EMBO J. 18:1999;1905-1914.
    • (1999) EMBO J , vol.18 , pp. 1905-1914
    • Ema, M.1    Hirota, K.2    Mimura, J.3    Abe, H.4    Yodoi, J.5    Sogawa, K.6    Poellinger, L.7    Fujii-Kuriyama, Y.8
  • 18
    • 0032511014 scopus 로고    scopus 로고
    • Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer
    • Liu Y., Christou H., Morita T., Laughner E., Semenza G.L., Kourembanas S. Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5′ enhancer. J Biol Chem. 273:1998;15257-15262.
    • (1998) J Biol Chem , vol.273 , pp. 15257-15262
    • Liu, Y.1    Christou, H.2    Morita, T.3    Laughner, E.4    Semenza, G.L.5    Kourembanas, S.6
  • 20
    • 0031957221 scopus 로고    scopus 로고
    • Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1
    • Martin C., Yu A.Y., Jiang B.-H., Davis L., Kimberly D., Hohimer A.R., Semenza G.L. Cardiac hypertrophy in chronically anemic fetal sheep Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1 . Am J Obstet Gynecol. 178:1998;527-534.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 527-534
    • Martin, C.1    Yu, A.Y.2    Jiang, B.-H.3    Davis, L.4    Kimberly, D.5    Hohimer, A.R.6    Semenza, G.L.7
  • 21
    • 0027970536 scopus 로고
    • Role of hydrogen peroxide in hypoxia-induced erythropoietin production
    • Fandrey J., Frede S., Jelkmann W. Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem J. 303:1994;507-510.
    • (1994) Biochem J , vol.303 , pp. 507-510
    • Fandrey, J.1    Frede, S.2    Jelkmann, W.3
  • 24
    • 0028844810 scopus 로고
    • Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia: Implications for the mechanism of oxygen sensing
    • Gleadle J.M., Ebert B.L., Ratcliffe P.J. Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia Implications for the mechanism of oxygen sensing . Eur J Biochem. 234:1995;92-99.
    • (1995) Eur J Biochem , vol.234 , pp. 92-99
    • Gleadle, J.M.1    Ebert, B.L.2    Ratcliffe, P.J.3
  • 26
    • 0032496159 scopus 로고    scopus 로고
    • Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes
    • Duranteau J., Chandel N.S., Kulisz A., Shao Z., Schumacker P.T. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem. 273:1998;11619-11624.
    • (1998) J Biol Chem , vol.273 , pp. 11619-11624
    • Duranteau, J.1    Chandel, N.S.2    Kulisz, A.3    Shao, Z.4    Schumacker, P.T.5
  • 27
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA binding activity: Implications for models of hypoxia signal transduction
    • Wang G.L., Semenza G.L. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA binding activity Implications for models of hypoxia signal transduction . Blood. 82:1993;3610-3615.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 30
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1α is required for solid tumor formation and embryonic vascularization
    • Ryan H.E., Lo J., Johnson R.S. HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J. 17:1998;3005-3015.
    • (1998) EMBO J , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 31
  • 32
    • 0033562569 scopus 로고    scopus 로고
    • Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
    • Kotch L.E., Iyer N.V., Laughner E., Semenza G.L. Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Dev Biol. 209:1999;254-267.
    • (1999) Dev Biol , vol.209 , pp. 254-267
    • Kotch, L.E.1    Iyer, N.V.2    Laughner, E.3    Semenza, G.L.4
  • 34
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 86:1996;353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 35
    • 0031969264 scopus 로고    scopus 로고
    • Angiogenesis and tumor metastasis
    • Zetter B.R. Angiogenesis and tumor metastasis. Annu Rev Med. 49:1998;407-424.
    • (1998) Annu Rev Med , vol.49 , pp. 407-424
    • Zetter, B.R.1
  • 36
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P., Kallinowski F., Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors A review . Cancer Res. 49:1989;6449-6465.
    • (1989) Cancer Res , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 37
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M., Schlenger K., Aral B., Mitze M., Schaffer U., Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56:1996;4509-4515.
    • (1996) Cancer Res , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 41
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D., Itin A., Soffer D., Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:1992;843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 42
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate K.H., Breier G., Weich H.A., Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 359:1992;845-848.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 43
    • 0030659531 scopus 로고    scopus 로고
    • V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: Involvement of HIF-1 in tumor progression
    • Jiang B.-H., Agani F., Passaniti A., Semenza G.L. V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1 Involvement of HIF-1 in tumor progression . Cancer Res. 57:1997;5328-5335.
    • (1997) Cancer Res , vol.57 , pp. 5328-5335
    • Jiang, B.-H.1    Agani, F.2    Passaniti, A.3    Semenza, G.L.4
  • 46
    • 0027938458 scopus 로고
    • Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas
    • Kanno H., Kondo K., Ito S., Yamamoto I., Fujii S., Torigoe S., Sakai N., Hosaka M., Shuin T., Yao M. Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas. Cancer Res. 54:1994;4845-4847.
    • (1994) Cancer Res , vol.54 , pp. 4845-4847
    • Kanno, H.1    Kondo, K.2    Ito, S.3    Yamamoto, I.4    Fujii, S.5    Torigoe, S.6    Sakai, N.7    Hosaka, M.8    Shuin, T.9    Yao, M.10
  • 47
    • 0033566693 scopus 로고    scopus 로고
    • Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2
    • Feldser D., Agani F., Iyer N.V., Pak B., Ferreira G., Semenza G.L. Reciprocal positive regulation of hypoxia-inducible factor 1α and insulin-like growth factor 2. Cancer Res. 59:1999;3915-3918.
    • (1999) Cancer Res , vol.59 , pp. 3915-3918
    • Feldser, D.1    Agani, F.2    Iyer, N.V.3    Pak, B.4    Ferreira, G.5    Semenza, G.L.6
  • 50
    • 0030945198 scopus 로고    scopus 로고
    • Aerobic glycolysis by proliferating cells: A protective strategy against reactive oxygen species
    • Brand K.A., Hermfisse U. Aerobic glycolysis by proliferating cells A protective strategy against reactive oxygen species . FASEB J. 11:1997;388-395.
    • (1997) FASEB J , vol.11 , pp. 388-395
    • Brand, K.A.1    Hermfisse, U.2
  • 51
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • Bergers G., Javaherian K., Lo K., Folkman J., Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science. 284:1999;808-812.
    • (1999) Science , vol.284 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.3    Folkman, J.4    Hanahan, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.