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Volumn 301, Issue 1, 2000, Pages 163-171

Apoptosis in multiple sclerosis

Author keywords

Apoptosis; Autoimmune disease; CD95; Multiple sclerosis; T cell; Therapy

Indexed keywords

FAS ANTIGEN;

EID: 0033926601     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410000179     Document Type: Review
Times cited : (63)

References (86)
  • 1
    • 0031659763 scopus 로고    scopus 로고
    • Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system transgenic mice
    • Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G, Probert L (1998) Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system transgenic mice. Am J Pathol 153:801-813
    • (1998) Am J Pathol , vol.153 , pp. 801-813
    • Akassoglou, K.1    Bauer, J.2    Kassiotis, G.3    Pasparakis, M.4    Lassmann, H.5    Kollias, G.6    Probert, L.7
  • 2
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281:1305-1308
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 3
    • 0032934534 scopus 로고    scopus 로고
    • Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice
    • Bachmann R, Eugster HP, Frei K, Fontana A, Lassmann H (1999) Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice. Am J Pathol 154:1417-1422
    • (1999) Am J Pathol , vol.154 , pp. 1417-1422
    • Bachmann, R.1    Eugster, H.P.2    Frei, K.3    Fontana, A.4    Lassmann, H.5
  • 5
    • 0033168749 scopus 로고    scopus 로고
    • FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: Evidence for the existence of an immunological brain barrier
    • Bechmann I, Mor G, Nilsen J, Eliza M, Nitsch R, Naftolin F (1999) FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier. Glia 27:62-74
    • (1999) Glia , vol.27 , pp. 62-74
    • Bechmann, I.1    Mor, G.2    Nilsen, J.3    Eliza, M.4    Nitsch, R.5    Naftolin, F.6
  • 8
    • 0030738366 scopus 로고    scopus 로고
    • Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
    • Bonetti B, Raine CS (1997) Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann Neurol 42:74-84
    • (1997) Ann Neurol , vol.42 , pp. 74-84
    • Bonetti, B.1    Raine, C.S.2
  • 17
    • 0029960673 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain
    • Dowling P, Shang G, Raval S, Menonna J, Cook S, Husar W (1996) Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J Exp Med 184:1513-1518
    • (1996) J Exp Med , vol.184 , pp. 1513-1518
    • Dowling, P.1    Shang, G.2    Raval, S.3    Menonna, J.4    Cook, S.5    Husar, W.6
  • 19
    • 0029802697 scopus 로고    scopus 로고
    • Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity
    • Drappa J, Vaishnaw AK, Sullivan KE, Chu JL, Elkon KB (1996) Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. N Engl J Med 335:1643-1649
    • (1996) N Engl J Med , vol.335 , pp. 1643-1649
    • Drappa, J.1    Vaishnaw, A.K.2    Sullivan, K.E.3    Chu, J.L.4    Elkon, K.B.5
  • 24
    • 0028172708 scopus 로고
    • The bcl-2 proto-oncogene is overexpressed in systemic lupus erythematosus
    • Gatenby PA, Irvine M (1994) The bcl-2 proto-oncogene is overexpressed in systemic lupus erythematosus. J Autoimmun 7:623-631
    • (1994) J Autoimmun , vol.7 , pp. 623-631
    • Gatenby, P.A.1    Irvine, M.2
  • 25
    • 0030757125 scopus 로고    scopus 로고
    • T-cell apoptosis in autoimmune diseases: Termination of inflammation in the nervous system and other sites with specialized immune-defense mechanisms
    • Gold R, Hartung HP, Lassmann H (1997) T-cell apoptosis in autoimmune diseases: termination of inflammation in the nervous system and other sites with specialized immune-defense mechanisms. Trends Neurosci 20:399-404
    • (1997) Trends Neurosci , vol.20 , pp. 399-404
    • Gold, R.1    Hartung, H.P.2    Lassmann, H.3
  • 26
    • 0031472042 scopus 로고    scopus 로고
    • Cell death: TRAIL and its receptors
    • Golstein P (1997) Cell death: TRAIL and its receptors. Curr Biol 7:R750-R753
    • (1997) Curr Biol , vol.7
    • Golstein, P.1
  • 28
    • 0032575412 scopus 로고    scopus 로고
    • Death by crowd control
    • Hengartner M (1998) Death by crowd control. Science 281:1298-1299
    • (1998) Science , vol.281 , pp. 1298-1299
    • Hengartner, M.1
  • 29
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 30
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • Hohlfeld R (1997) Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. Brain 120:865-916
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 31
    • 0031572509 scopus 로고    scopus 로고
    • Maintenance of clonotypic specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes
    • Hornung F, Zheng L, Lenardo MJ (1997) Maintenance of clonotypic specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes. J Immunol 159:3816-3822
    • (1997) J Immunol , vol.159 , pp. 3816-3822
    • Hornung, F.1    Zheng, L.2    Lenardo, M.J.3
  • 32
    • 0030996690 scopus 로고    scopus 로고
    • Detection of the soluble form of the Fas molecule in patients with multiple sclerosis and human T-lymphotropic virus type I-associated myelopathy
    • Inoue A, Koh C, Sakai T, Yamazaki M, Yanagisawa N, Usuku K, Osame M (1997) Detection of the soluble form of the Fas molecule in patients with multiple sclerosis and human T-lymphotropic virus type I-associated myelopathy. J Neuroimmunol 75:141-146
    • (1997) J Neuroimmunol , vol.75 , pp. 141-146
    • Inoue, A.1    Koh, C.2    Sakai, T.3    Yamazaki, M.4    Yanagisawa, N.5    Usuku, K.6    Osame, M.7
  • 33
    • 0031922935 scopus 로고    scopus 로고
    • Soluble antigen therapy induces apoptosis of autoreactive T cells preferentially in the target organ rather than in the peripheral lymphoid organs
    • Ishigami T, White CA, Pender MP (1998) Soluble antigen therapy induces apoptosis of autoreactive T cells preferentially in the target organ rather than in the peripheral lymphoid organs. Eur J Immunol 28:1626-1635
    • (1998) Eur J Immunol , vol.28 , pp. 1626-1635
    • Ishigami, T.1    White, C.A.2    Pender, M.P.3
  • 34
    • 0033599730 scopus 로고    scopus 로고
    • Interferon-beta 1b augments activation-induced T-cell death in multiple sclerosis patients
    • Kaser A, Deisenhammer F, Berger T, Tilg H (1999) Interferon-beta 1b augments activation-induced T-cell death in multiple sclerosis patients. Lancet 353:1413-1414
    • (1999) Lancet , vol.353 , pp. 1413-1414
    • Kaser, A.1    Deisenhammer, F.2    Berger, T.3    Tilg, H.4
  • 35
    • 0033491193 scopus 로고    scopus 로고
    • CD95(APO-1/Fas)-mediated apoptosis: Live and let die
    • Krammer PH (1998) CD95(APO-1/Fas)-mediated apoptosis: live and let die. Adv Immunol 71:163-210
    • (1998) Adv Immunol , vol.71 , pp. 163-210
    • Krammer, P.H.1
  • 36
    • 0033215505 scopus 로고    scopus 로고
    • Bcl-2 expressing oligodendrocytes in multiple sclerosis lesions
    • Kuhlmann T, Lucchinetti CF, Zettl U, Brück W (1999) Bcl-2 expressing oligodendrocytes in multiple sclerosis lesions. Glia 28:34-39
    • (1999) Glia , vol.28 , pp. 34-39
    • Kuhlmann, T.1    Lucchinetti, C.F.2    Zettl, U.3    Brück, W.4
  • 39
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo M, Chan FK, Hornung F, McFarland H, Siegel R, Wang J, Zheng L (1999) Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 17:221-253
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, F.K.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 40
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicate heterogeneity in pathogenesis
    • Lucchinetti CF, Brück W, Moses R, Lassmann H (1996) Distinct patterns of multiple sclerosis pathology indicate heterogeneity in pathogenesis. Brain Pathol 6:259-274
    • (1996) Brain Pathol , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Brück, W.2    Moses, R.3    Lassmann, H.4
  • 41
    • 0033525162 scopus 로고    scopus 로고
    • Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis
    • Macchi B, Matteucci C, Nocentini U, Caltagirone C, Mastino A (1999) Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis. Neuroreport 10:399-402
    • (1999) Neuroreport , vol.10 , pp. 399-402
    • Macchi, B.1    Matteucci, C.2    Nocentini, U.3    Caltagirone, C.4    Mastino, A.5
  • 42
    • 0031445439 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-induced encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas-and Fas ligand-deficient lpr and gld mice
    • Malipiero U, Frei K, Spanaus K-S, Agresti C, Lassmann H, Hahne M, Tschopp J, Eugster H-P, Fontana A (1997) Myelin oligodendrocyte glycoprotein-induced encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas-and Fas ligand-deficient lpr and gld mice. Eur J Immunol 27: 3151-3160
    • (1997) Eur J Immunol , vol.27 , pp. 3151-3160
    • Malipiero, U.1    Frei, K.2    Spanaus, K.-S.3    Agresti, C.4    Lassmann, H.5    Hahne, M.6    Tschopp, J.7    Eugster, H.-P.8    Fontana, A.9
  • 45
    • 0032772860 scopus 로고    scopus 로고
    • Immunopathogenesis of multiple sclerosis: The role of T cells
    • Martino G, Hartung HP (1999) Immunopathogenesis of multiple sclerosis: the role of T cells. Curr Opin Immunol 12:309-321
    • (1999) Curr Opin Immunol , vol.12 , pp. 309-321
    • Martino, G.1    Hartung, H.P.2
  • 47
    • 0033067355 scopus 로고    scopus 로고
    • Differential T cell response in central and peripheral nerve injury: Connection with immune privilege
    • Moalem G, Monsonego A, Shani Y, Cohen IR, Schwartz M (1999) Differential T cell response in central and peripheral nerve injury: connection with immune privilege. FASEB J 13:1207-1217
    • (1999) FASEB J , vol.13 , pp. 1207-1217
    • Moalem, G.1    Monsonego, A.2    Shani, Y.3    Cohen, I.R.4    Schwartz, M.5
  • 48
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S, Golstein P (1995) The Fas death factor. Science 267: 1449-1456
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 51
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman ZL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, Z.L.2    Korsmeyer, S.J.3
  • 52
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G, Ni J, Wei Y, Yu G, Gentz R, Dixit VM (1997) An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277:815-818
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 55
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC (1994) Bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 56
    • 0033118470 scopus 로고    scopus 로고
    • Interferon (IFN)-beta treatment enhances CD95 and interleukin 10 expression but reduces interferon-gamma producing T cells in MS patients
    • Rep MH, Schrijver HM, van LT, Hintzen RQ, Roos MT, Ader HJ, Polman CH, van LR (1999) Interferon (IFN)-beta treatment enhances CD95 and interleukin 10 expression but reduces interferon-gamma producing T cells in MS patients. J Neuroimmunol 96:92-100
    • (1999) J Neuroimmunol , vol.96 , pp. 92-100
    • Rep, M.H.1    Schrijver, H.M.2    Van, L.T.3    Hintzen, R.Q.4    Roos, M.T.5    Ader, H.J.6    Polman, C.H.7    Van, L.R.8
  • 58
    • 0032127022 scopus 로고    scopus 로고
    • Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells
    • Roth W, Wagenknecht B, Dichgans J, Weller M (1998) Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells. J Neuroimmunol 87:121-129
    • (1998) J Neuroimmunol , vol.87 , pp. 121-129
    • Roth, W.1    Wagenknecht, B.2    Dichgans, J.3    Weller, M.4
  • 60
    • 0031252369 scopus 로고    scopus 로고
    • Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
    • Sabelko KA, Kelly KA, Nahm MH, Cross AH, Russell JH (1997) Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J Immunol 159:3096-3099
    • (1997) J Immunol , vol.159 , pp. 3096-3099
    • Sabelko, K.A.1    Kelly, K.A.2    Nahm, M.H.3    Cross, A.H.4    Russell, J.H.5
  • 61
    • 0033583427 scopus 로고    scopus 로고
    • Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
    • Sabelko-Downes DK, Cross AH, Russell JH (1999) Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J Exp Med 189:1195-1205
    • (1999) J Exp Med , vol.189 , pp. 1195-1205
    • Sabelko-Downes, D.K.1    Cross, A.H.2    Russell, J.H.3
  • 62
    • 0030861145 scopus 로고    scopus 로고
    • Multiple sclerosis: Comparison of the human T cell response to S100β and MBP reveals parallels to rat experimental autoimmune panencephalitis (EAP)
    • Schmidt S, Linington C, Zipp F, Sotigui S, de Waal Malefyt R, Weckerle H, Hohlfeld R (1997) Multiple sclerosis: comparison of the human T cell response to S100β and MBP reveals parallels to rat experimental autoimmune panencephalitis (EAP). Brain 120:1437-1445
    • (1997) Brain , vol.120 , pp. 1437-1445
    • Schmidt, S.1    Linington, C.2    Zipp, F.3    Sotigui, S.4    De Waal Malefyt, R.5    Weckerle, H.6    Hohlfeld, R.7
  • 63
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M, Breitschopf H, Gold R, Zischler H, Rothe G, Wekerle H, Lassmann H (1993) Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: evidence for programmed cell death as a mechanism to control inflammation in the brain. Am J Pathol 143:446-452
    • (1993) Am J Pathol , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 65
    • 0025827448 scopus 로고
    • Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin
    • Selmaj K, Raine C, Farooq M, Morton W, Brosnan C (1991) Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin. J Immunol 147:1522-1529
    • (1991) J Immunol , vol.147 , pp. 1522-1529
    • Selmaj, K.1    Raine, C.2    Farooq, M.3    Morton, W.4    Brosnan, C.5
  • 67
    • 0033954469 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
    • Suvannavejh GC, Dal Canto MC, Matis LA, Miller SD (2000) Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. J Clin Invest 105: 223-231
    • (2000) J Clin Invest , vol.105 , pp. 223-231
    • Suvannavejh, G.C.1    Dal Canto, M.C.2    Matis, L.A.3    Miller, S.D.4
  • 69
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and bcl-2 regulate T cell responses to model self and foreign antigens
    • van Parijs L, Peterson DA, Abbas AK (1998) The Fas/Fas ligand pathway and bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 8:265-274
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 70
    • 0031253737 scopus 로고    scopus 로고
    • Fas-and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
    • Waldner H, Sobel RA, Howard E, Kuchroo VK (1997) Fas-and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. J Immunol 159:3100-3103
    • (1997) J Immunol , vol.159 , pp. 3100-3103
    • Waldner, H.1    Sobel, R.A.2    Howard, E.3    Kuchroo, V.K.4
  • 72
    • 0028178471 scopus 로고
    • Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
    • Weller M, Constam DB, Malipiero U, Fontana A (1994) Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur J Immunol 24:1293-1300
    • (1994) Eur J Immunol , vol.24 , pp. 1293-1300
    • Weller, M.1    Constam, D.B.2    Malipiero, U.3    Fontana, A.4
  • 73
    • 0033954458 scopus 로고    scopus 로고
    • Partial synergy of bisindolylmaleimide with apoptotic stimulus in antigen-specific T cells - Implications for multiple sclerosis
    • Wendung U, Aktas O, Schmierer K, Zschenderlein R, Zipp F (2000) Partial synergy of bisindolylmaleimide with apoptotic stimulus in antigen-specific T cells - implications for multiple sclerosis. J Neuroimmunol 103:69-75
    • (2000) J Neuroimmunol , vol.103 , pp. 69-75
    • Wendung, U.1    Aktas, O.2    Schmierer, K.3    Zschenderlein, R.4    Zipp, F.5
  • 74
    • 0032005153 scopus 로고    scopus 로고
    • The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis
    • White CA, McCombe PA, Pender MP (1998) The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. J Neuroimmunol 82:47-55
    • (1998) J Neuroimmunol , vol.82 , pp. 47-55
    • White, C.A.1    McCombe, P.A.2    Pender, M.P.3
  • 76
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl-2 family and cell death
    • Yang E, Korsmeyer SJ (1997) Molecular thanatopsis: a discourse on the bcl-2 family and cell death. Blood 88:386-401
    • (1997) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2
  • 78
    • 0031826454 scopus 로고    scopus 로고
    • Bcl-2 expressing T lymphocytes in multiple sclerosis lesions
    • Zettl UK, Kuhlmann T, Brück W (1998) Bcl-2 expressing T lymphocytes in multiple sclerosis lesions. Neuropathol Appl Neurobiol 24:202-208
    • (1998) Neuropathol Appl Neurobiol , vol.24 , pp. 202-208
    • Zettl, U.K.1    Kuhlmann, T.2    Brück, W.3
  • 79
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang J, Markovic-Plese S, Lacet B, Raus J, Weiner HL, Hafler DA (1994) Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J Exp Med 179:973-984
    • (1994) J Exp Med , vol.179 , pp. 973-984
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6
  • 80
    • 0033010882 scopus 로고    scopus 로고
    • Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases
    • Zhou T, Song L, Yang P, Wang Z, Lui D, Jope RS (1999) Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases. Nat Med 5:42-48
    • (1999) Nat Med , vol.5 , pp. 42-48
    • Zhou, T.1    Song, L.2    Yang, P.3    Wang, Z.4    Lui, D.5    Jope, R.S.6
  • 81
    • 0031227661 scopus 로고    scopus 로고
    • Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by recombinant CD95 ligand
    • Zipp F, Martin R, Lichtenfels R, Roth W, Dichgans J, Krammer PH, Weller M (1997) Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by recombinant CD95 ligand. J Immunol 159:2108-2115
    • (1997) J Immunol , vol.159 , pp. 2108-2115
    • Zipp, F.1    Martin, R.2    Lichtenfels, R.3    Roth, W.4    Dichgans, J.5    Krammer, P.H.6    Weller, M.7
  • 82
    • 0031809468 scopus 로고    scopus 로고
    • CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis. No differences from normal individuals and no relation to HLA-DR2
    • Zipp F, Faber E, Sommer N, Müller C, Dichgans J, Krammer PH, Martin R, Weller M (1998a) CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis. No differences from normal individuals and no relation to HLA-DR2. J Neuroimmunol 81:168-172
    • (1998) J Neuroimmunol , vol.81 , pp. 168-172
    • Zipp, F.1    Faber, E.2    Sommer, N.3    Müller, C.4    Dichgans, J.5    Krammer, P.H.6    Martin, R.7    Weller, M.8
  • 83
    • 0032525797 scopus 로고    scopus 로고
    • Serum CD95 of multiple sclerosis patients protects from CD95-mediated apoptosis
    • Zipp F, Otzelberger K, Dichgans J, Martin R, Weller M (1998b) Serum CD95 of multiple sclerosis patients protects from CD95-mediated apoptosis. J Neuroimmunol 86:151-154
    • (1998) J Neuroimmunol , vol.86 , pp. 151-154
    • Zipp, F.1    Otzelberger, K.2    Dichgans, J.3    Martin, R.4    Weller, M.5
  • 85
    • 0033486001 scopus 로고    scopus 로고
    • Immune (dys)regulation in multiple sclerosis: Role of the CD95/CD95 ligand system
    • Zipp F, Krammer PH, Weller M (1999) Immune (dys)regulation in multiple sclerosis: role of the CD95/CD95 ligand system. Immunol Today 20:550-554
    • (1999) Immunol Today , vol.20 , pp. 550-554
    • Zipp, F.1    Krammer, P.H.2    Weller, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.