Multiple sclerosis: Fas signaling in oligodendrocyte cell death

Journal of Experimental Medicine

Volumn 184, Issue 6, 1996, Pages 2361-2370

  D'Souza, Sameer D ^a   Bonetti, Bruno ^c   Balasingam, Vijayabalan ^a   Cashman, Neil R ^a   Barker, Philip A ^a   Troutt, Anthony B ^b   Raine, Cedric S ^c   Antel, Jack P ^a  

^a MCGILL UNIVERSITY   (Canada)

^b AMGEN INC   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; DNA FRAGMENT; FAS ANTIGEN; LACTATE DEHYDROGENASE; MONOCLONAL ANTIBODY; TRYPAN BLUE;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOLYSIS; DEMYELINATION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADULT; ANTIGENS, CD95; CELL DEATH; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; MULTIPLE SCLEROSIS; NEUROGLIA; OLIGODENDROGLIA; REFERENCE VALUES; SIGNAL TRANSDUCTION;

EID: 0030469753     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.6.2361     Document Type: Article

References (54)

1. Dawson, J.W. 1916. The histology of disseminated sclerosis. Trans. R. Soc. Edin. 50:517-540.
2. Lumsden, C.E. 1955. Neuropathology of multiple sclerosis. In Multiple Sclerosis. D. McAlpine, N.D. Compston, and C.E. Lumsden, editors. Livingstone Press Inc., Edinburgh. 208-293.
3. Prineas, J.W. 1985. Neuropathology of multiple sclerosis. In Handbook of Clinical Neurology: Demyelinating Diseases. P.J. Vinken, G.W. Bruyn, and H.L. Klawans, editors. Elsevier Science Publishing Co. Inc., New York. 213-257.
4. Raine, C.S. 1990. Demyelinating diseases. In Textbook of Neuropathology. R.L. Davis and D.M. Robertson, editors. Williams and Wilkins, Baltimore, MD. 535-620.
5. Raine, C.S. 1994. The Dale E. McFarlin Memorial Lecture: the immunology of the multiple sclerosis lesion. Ann. Neurol. 36:561-572.
6. Raine, C.S., and L.C. Scheinberg. 1988. On the immunopathology of plaque development and repair in multiple sclerosis. J. Neuroimmunol. 20:189-201.
7. Ozawa, K., G. Schunek, H. Breitschopf, W. Bruck, H. Budka, K. Jellinger, and H. Lassmann. 1994. Patterns of oligodendroglia pathology in multiple sclerosis. Brain. 117: 1311-1322.
8. Lee, S.C., and C.S. Raine. 1989. Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules. J. Neuroimmunol. 25: 261-266.
9. Selmaj, K.W., and C.S. Raine. 1988. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 23:339-346.
10. Selmaj, K., C.S. Raine, M. Farooq, W.T. Norton, and C.F. Brosnan. 1991. Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin. J. Immunol. 147: 1522-1529.
11. D'Souza, S.D., K. Alinauskas, E. McRea, C. Goodyer, and J.P Antel. 1995. Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury. J. Neurosci. 15:7293-7300.
12. Wilt, S.G., E. Milward, J.M. Zhou, K. Nagasato, H. Patton, R. Rusten, D.E. Griffin, M. O'Connor, and M. Dubois-Dalcq. 1995. In vitro evidence for a dual role of tumour necrosis factor-alpha in human immunodeficiency virus type I encephalopathy. Ann. Neurol. 37:381-394.
13. Kim, Y.S., and S.U. Kim. 1991. Oligodendroglial cell death induced by oxygen radicals and its protection by catalase. J. Neurosci. Res. 29:100-106
14. Lee, S.C., D.W. Dickson, W. Liu, and C.F. Brosnan. 1993. Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma. J. Neuroimmunol. 46:19-24.
15. Ruijs, T.C.G., M.S. Freedman, G. Grenier, A. Olivier, and J.P. Antel. 1990. Human oligodendrocytes are susceptible to cytolysis by major histocompatibility complex class I-restricted lymphocytes. J. Neuroimmunol. 27:89-97.
16. Freedman, M.S., T.C.G. Ruijs, L.K. Selin, and J.P. Antel. 1991. Peripheral blood gamma-delta T cells lyse fresh human brain-derived oligodendrocytes. Ann. Neurol. 30:794-800.
17. Merrill, J.E., and R.P. Zimmermann. 1991. Natural and induced cytotoxicity of oligodendrocytes by microglia is inhibitable by TGF-beta. Glia. 4:327-331.
18. Zajicek, J.P., M. Wing, N.J. Scolding, and D.A.S. Compston. 1992. Interactions between oligodendrocytes and microglia. A major role for complement and tumour necrosis factor in oligodendrocyte adherence and killing. Brain. 115: 1611-1631.
19. + T cells independent of tumor necrosis factor. Ann. Neurol. 35:341-348.
20. Suda, T., and S. Nagata. 1994. Purification and characterization of the fas-ligand that induces apoptosis. J. Exp. Med. 179:873-879.
21. Nagata, S., and P. Golstein. 1995. The fas death factor. Science (Wash. DC). 267:1449-1456.
22. Aggarwal, B.B., S. Singh, R. LaPushin, and K. Totpal. 1995. Fas antigen signals proliferation of normal human diploid fibroblasts and its mechanism is different from tumour necrosis factor receptor. FEBS Lett. 364:5-8.
23. Badley, A.D., J.A. Mcelhinny, P.J. Leibson, D.H. Lynch, M.R. Alderson, and C.V. Paya. 1996. Upregulation of fas ligand by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol. 70:199-206.
24. Kagi, D., F. Vignaux, B. Ledermann, K. Burki, V. Depraetere, S. Nagata, H. Hengartner, and P. Golstein. 1994. Fas and perform pathways as major mechanisms of T cell mediated cytotoxicity. Science (Wash. DC). 265:528-530.
25. + T cell-mediated cytotoxicity. J. Immunol. 152:1127-1133.
26. + Th1 clones. Cell. Immunol. 163:237-244.
27. Golstein, P. 1995. Fas-based T cell-mediated cytotoxicity. Curr. Top. Microbiol. & Immunol. 198:25-27.
28. Berke, G. 1995. The CTL's kiss of death. Cell. 81:8-12.
29. Watanabe-Fukunaga, R., C.I. Brannan, N. Itoh, S. Yonehara, N.G. Copeland, N.A. Jenkins, and S. Nagata. 1992. The cDNA structure, expression, and chromosomal assignment of the mouse fas antigen. J. Immunol. 148:1274-1279.
30. Matsuyama, T., R. Hata, H. Tagaya, Y. Yamamoto, T. Nakajima, J. Furuyama, A. Wanaka, and M. Sugita. 1995. Fas antigen mRNA induction in postischemic murine brain. Brain Res. 657:342-346.
31. Nishimura, T., H. Akiyama, S. Yonehara, H. Kondo, K. Ikeda, H. Kato, E. Iseki, and K. Kosaka. 1995. Fas antigen expression in brains of patients with Alzheimer-type dementia. Brain Res. 695:137-145.
32. Yong, V.W., and J.P. Antel. 1992. Culture of glial cells from human brain biopsies. In Protocols for Neural Cell Culture. S. Fedoroff and A. Richardson, editors. Humana Press, Clifton, NJ. 76-81.
33. Walsh, M., A.A. Glass, V. Chiu, and V.W. Clark. 1994. The role of the fas lyric pathway in a perform-less CTL hybridoma. J. Immunol. 153:2506-2514.
34. Chow, S.C., M. Weis, G.E. Kass, T.H. Holmstrom, J.E. Erikkson, and S. Orrenius. 1995. Involvement of multiple proteases during fas-mediated apoptosis in T lymphocytes. FEBS (Fed. Eur. Biochem. Soc.) Lett. 364:134-138.
35. Sumimoto, S., T. Ishigami, Y. Horiguchi, S. Yonehara, S. Kanazashi, T. Heike, K. Katamura, and M. Mayumi. 1994. Anti-fas antibody induces different types of cell death in the human histiocytic cell line, U937, and the B cell line, B104: the role of single-strand DNA breaks and poly (ADP-ribosyl)ation in cell death. Cell. Immunol. 153:184-193.
36. Weller, M., K. Frei, P. Groscurth, P.H. Krammer, Y. Yonekawa, and A. Fontana. 1994. Anti-fas (APO-1) antibody-mediated apoptosis of cultured human glioma. Induction and modulation of sensitivity by cytokines. J. Clin. Invest. 94: 953-964.
37. Lynch, D.H. 1995. Biology of fas. Circ. Shock. 44:63-66.
38. Cifone, M.G., R. DeMaria, P. Roncaioli, M.R. Rippo, M. Azuma, L.L. Lanier, A. Santoni, and R. Testi. 1994. Apoptotic signaling through CD95 (Fas/APO-1) activates an acidic sphingomyelinase. J. Exp. Med. 180:1547-1552.
39. Gulbins, E., R. Bissonnette, A. Mahboubi, S. Martin, W. Nishioka, T. Brunner, G. Baier, G. Baier-Bitterlich, C. Byrd, and F. Lang. 1995. Fas-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity. 2:341-351.
40. Obeid, L.M., C.M. Linardic, L.A. Karolak, and Y.A. Hannun. 1993. Programmed cell death induced by ceramide. Science (Wash. DC). 259:1769-1771.
41. Tepper, C.G., S. Jayader, B. Liu, A. Bielawska, R. Wolff, S. Yonehara, Y.A. Hannun, and M.F. Seldin. 1995. Role for ceramide as an endogenous mediator of fas-induced cytotoxicity. Proc. Natl. Acad. Sci. USA. 92:8443-8447.
42. Verheij, M., R. Bose, X.H. Lin, B. Yao, B. Jarvis, W.D. Jarvis, S. Grant, M.J. Birrer, E. Szabo, L.I. Zon, et al. 1996. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature (Lond). 380:75-79.
43. Prabhakar, S., S.D. D'Souza, J.P. Antel, J. McLaurin, H.M. Schipper, and E. Wang. 1995. Phenotype and cell cycle properties of human oligodendrocytes in vitro. Brain Res. 672:159-169.
44. D'Souza, S.D., K.A. Alinauskas, and J.P. Antel. 1996. Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury. J. Neurosci. Res. 43:289-298.
45. Louis, J.C., E. Magal, S. Takayama, and S. Varon. 1993. CNTF protection of oligodendrocytes against natural and TNF-induced death. Science (Wash. DC). 259:689-692.
46. Kahn, M.A., and J. DeVellis. 1994. Regulation of an oligodendrocyte progenitor cell line by the interleukin-6 family of cytokines. Glia. 12:87-98.
47. Yonehara, S., A. Ishii, and M.J. Yonehara. 1989. A cell killing monoclonal antibody (anti-fas) to a cell surface antigen co-downregulated with the receptor of TNF. J. Exp. Med. 169:1747-1756.
48. Moller, P., C. Henne, F. Leithauser, A. Eichelmann, A. Schmidt, S. Bruderlein, J. Dhein, and P.H. Krammer. 1993. (Deregulation of the APO-1 antigen with intracellular adhesion molecule-1 (CD54) in tonsiliar B cells and coordinate expression in follicular center B cells and in follicle center and mediastinal B-cell lymphomas. Blood. 81:2067-2075.
49. Raine, C.S. 1994. Multiple sclerosis: immune system molecule expression in the central nervous system. J. Neuropathol. Exp. Neurol. 53:328-337.
50. Griot, C., M. Vandervelde, A. Richard, E. Peterhans, and R. Stocker. 1990. Selective degeneration of oligodendrocytes mediated by reactive oxygen species. Free Rad. Res. Commun. 11:181-193.
51. + oligodendrocytes in multiple sclerosis. Proc. Natl. Acad. Sci. USA. 88:6452-6456.
52. + T cells respond to mycobacterial heat shock protein. Nature (Lond.). 340:309-312.
53. Indreshpal, K., S.D. Voss, R.S. Gupta, K. Schell, P. Fisch, and P.M. Sondel. 1993. Human peripheral γβ-T cells recognize hsp60 molecules on Daudi Burkitts lymphoma cells. J. Immunol. 150:2046-2055.
54. D'Souza, S.D., J.P. Antel, and M.S. Freedman. 1994. Cytokine induction of heat shock protein expression in human oligodendrocytes: an interlukin-1-mediated mechanism. J. Neuroimmunol. 50:17-24.