메뉴 건너뛰기




Volumn 82, Issue 1, 1998, Pages 47-55

The roles of Fas, Fas ligand and Bcl-2 in T cell apoptosis in the central nervous system in experimental autoimmune encephalomyelitis

Author keywords

Autoimmunity; Bcl 2; Experimental autoimmune encephalomyelitis; Fas (CD95); T cell apoptosis

Indexed keywords

FAS ANTIGEN; MYELIN BASIC PROTEIN; PROTEIN BCL 2;

EID: 0032005153     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(97)00187-2     Document Type: Article
Times cited : (67)

References (50)
  • 4
    • 0027143640 scopus 로고
    • Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis
    • Bossu P., Singer G.G., Andres P., Ettinger R., Marshak-Rothstein A., Abbas A.K. Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis. J. Immunol. 151:1993;7233-7239.
    • (1993) J. Immunol. , vol.151 , pp. 7233-7239
    • Bossu, P.1    Singer, G.G.2    Andres, P.3    Ettinger, R.4    Marshak-Rothstein, A.5    Abbas, A.K.6
  • 6
    • 0029046693 scopus 로고
    • Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal
    • Broome H.E., Dargan C.M., Krajewski S., Reed J.C. Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal. J. Immunol. 155:1995;2311-2317.
    • (1995) J. Immunol. , vol.155 , pp. 2311-2317
    • Broome, H.E.1    Dargan, C.M.2    Krajewski, S.3    Reed, J.C.4
  • 8
    • 0024530958 scopus 로고
    • Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different
    • Burns F.R., Li X.B., Shen N., Offner H., Chou Y.K., Vandenbark A.A., Heber-Katz E. Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different. J. Exp. Med. 169:1989;27-39.
    • (1989) J. Exp. Med. , vol.169 , pp. 27-39
    • Burns, F.R.1    Li, X.B.2    Shen, N.3    Offner, H.4    Chou, Y.K.5    Vandenbark, A.A.6    Heber-Katz, E.7
  • 10
    • 0024603242 scopus 로고
    • T cell receptor beta chain usage in myelin basic protein-specific rat T lymphocytes
    • Chluba J., Steeg C., Becker A., Wekerle H., Epplen J.T. T cell receptor beta chain usage in myelin basic protein-specific rat T lymphocytes. Eur. J. Immunol. 19:1989;279-284.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 279-284
    • Chluba, J.1    Steeg, C.2    Becker, A.3    Wekerle, H.4    Epplen, J.T.5
  • 11
    • 0022378690 scopus 로고
    • Ia antigens in the normal rat nervous system and in lesions of experimental allergic encephalomyelitis
    • Craggs R.I., Webster H.D. Ia antigens in the normal rat nervous system and in lesions of experimental allergic encephalomyelitis. Acta. Neuropathol. Berl. 68:1985;263-272.
    • (1985) Acta. Neuropathol. Berl. , vol.68 , pp. 263-272
    • Craggs, R.I.1    Webster, H.D.2
  • 12
    • 0015264390 scopus 로고
    • Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species
    • Deibler G.E., Martenson R.E., Kies M.W. Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 2:1972;139-165.
    • (1972) Prep. Biochem. , vol.2 , pp. 139-165
    • Deibler, G.E.1    Martenson, R.E.2    Kies, M.W.3
  • 13
    • 0027537118 scopus 로고
    • Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2
    • Deng G., Podack E.R. Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc. Natl. Acad. Sci. USA. 90:1993;2189-2193.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2189-2193
    • Deng, G.1    Podack, E.R.2
  • 16
    • 0028152659 scopus 로고
    • Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes
    • Fang W., Rivard J.J., Mueller D.L., Behrens T.W. Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes. J. Immunol. 153:1994;4388-4398.
    • (1994) J. Immunol. , vol.153 , pp. 4388-4398
    • Fang, W.1    Rivard, J.J.2    Mueller, D.L.3    Behrens, T.W.4
  • 17
    • 0021191999 scopus 로고
    • Astrocytes present myelin basic protein to encephalitogenic T-cell lines
    • Fontana A., Fierz W., Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature. 307:1984;273-276.
    • (1984) Nature , vol.307 , pp. 273-276
    • Fontana, A.1    Fierz, W.2    Wekerle, H.3
  • 18
    • 0029848128 scopus 로고    scopus 로고
    • Microglia induce CD4 T lymphocyte final effector function and death
    • Ford A.L., Foulcher E., Lemckert F.A., Sedgwick J.D. Microglia induce CD4 T lymphocyte final effector function and death. J. Exp. Med. 184:1996;1737-1745.
    • (1996) J. Exp. Med. , vol.184 , pp. 1737-1745
    • Ford, A.L.1    Foulcher, E.2    Lemckert, F.A.3    Sedgwick, J.D.4
  • 19
    • 0029995766 scopus 로고    scopus 로고
    • A license to kill
    • Fraser A., Evan G. A license to kill. Cell. 85:1996;781-784.
    • (1996) Cell , vol.85 , pp. 781-784
    • Fraser, A.1    Evan, G.2
  • 20
    • 0023618311 scopus 로고
    • Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells
    • Frei K., Siepl C., Groscurth P., Bodmer S., Schwerdel C., Fontana A. Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. Eur. J. Immunol. 17:1987;1271-1278.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1271-1278
    • Frei, K.1    Siepl, C.2    Groscurth, P.3    Bodmer, S.4    Schwerdel, C.5    Fontana, A.6
  • 21
    • 0029892006 scopus 로고    scopus 로고
    • Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T cell apoptosis in vivo
    • Gold R., Schmied M., Tontsch U., Hartung H.P., Wekerle H., Toyka K.V., Lassmann H. Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T cell apoptosis in vivo. Brain. 119:1996;651-659.
    • (1996) Brain , vol.119 , pp. 651-659
    • Gold, R.1    Schmied, M.2    Tontsch, U.3    Hartung, H.P.4    Wekerle, H.5    Toyka, K.V.6    Lassmann, H.7
  • 22
    • 0029000951 scopus 로고
    • Prevention and treatment of Lewis rat experimental allergic encephalomyelitis with a monoclonal antibody to the T cell receptor Vβ8.2 segment
    • Imrich H., Kugler C., Torres-Nagel N., Dorries R., Hunig T. Prevention and treatment of Lewis rat experimental allergic encephalomyelitis with a monoclonal antibody to the T cell receptor Vβ8.2 segment. Eur. J. Immunol. 25:1995;1960-1964.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1960-1964
    • Imrich, H.1    Kugler, C.2    Torres-Nagel, N.3    Dorries, R.4    Hunig, T.5
  • 23
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh N., Tsujimoto Y., Nagata S. Effect of bcl-2 on Fas antigen-mediated cell death. J. Immunol. 151:1993;621-627.
    • (1993) J. Immunol. , vol.151 , pp. 621-627
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 26
    • 0022591581 scopus 로고
    • Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology
    • Matsumoto Y., Hara N., Tanaka R., Fujiwara M. Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology. J. Immunol. 136:1986;3668-3676.
    • (1986) J. Immunol. , vol.136 , pp. 3668-3676
    • Matsumoto, Y.1    Hara, N.2    Tanaka, R.3    Fujiwara, M.4
  • 27
    • 0026621411 scopus 로고
    • Expression of CD45RC and Ia antigen in the spinal cord in acute experimental allergic encephalomyelitis: An immunocytochemical and flow cytometric study
    • McCombe P.A., Fordyce B.W., de Jersey J., Yoong G., Pender M.P. Expression of CD45RC and Ia antigen in the spinal cord in acute experimental allergic encephalomyelitis: an immunocytochemical and flow cytometric study. J. Neurol. Sci. 113:1992;177-186.
    • (1992) J. Neurol. Sci. , vol.113 , pp. 177-186
    • McCombe, P.A.1    Fordyce, B.W.2    De Jersey, J.3    Yoong, G.4    Pender, M.P.5
  • 28
    • 0030200641 scopus 로고    scopus 로고
    • + T lymphocytes in the spinal cord during recovery from experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein
    • + T lymphocytes in the spinal cord during recovery from experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein. J. Neurol. Sci. 139:1996;1-6.
    • (1996) J. Neurol. Sci. , vol.139 , pp. 1-6
    • McCombe, P.A.1    Nickson, I.2    Tabi, Z.3    Pender, M.P.4
  • 31
    • 0027177927 scopus 로고
    • In vivo antigen presentation by both brain parenchymal cells and hematopoietically derived cells during the induction of experimental autoimmune encephalomyelitis
    • Myers K.J., Dougherty J.P., Ron Y. In vivo antigen presentation by both brain parenchymal cells and hematopoietically derived cells during the induction of experimental autoimmune encephalomyelitis. J. Immunol. 151:1993;2252-2260.
    • (1993) J. Immunol. , vol.151 , pp. 2252-2260
    • Myers, K.J.1    Dougherty, J.P.2    Ron, Y.3
  • 32
    • 0027938156 scopus 로고
    • Bcl-2 and Bcl-x: Regulatory switches for lymphoid death and survival
    • Núñez G., Merino R., Grillot D., Gonzalez-Garcia M. Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival. Immunol. Today. 15:1994;582-588.
    • (1994) Immunol. Today , vol.15 , pp. 582-588
    • Núñez, G.1    Merino, R.2    Grillot, D.3    Gonzalez-Garcia, M.4
  • 33
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 34
    • 0022529785 scopus 로고
    • Ascending impairment of nociception in rats with experimental allergic encephalomyelitis
    • Pender M.P. Ascending impairment of nociception in rats with experimental allergic encephalomyelitis. J. Neurol. Sci. 75:1986;317-328.
    • (1986) J. Neurol. Sci. , vol.75 , pp. 317-328
    • Pender, M.P.1
  • 35
    • 0001445114 scopus 로고
    • Experimental autoimmune encephalomyelitis
    • In: Pender, M.P., McCombe, P.A. (Eds.) Cambridge University Press, Cambridge
    • Pender, M.P., 1995. Experimental autoimmune encephalomyelitis. In: Pender, M.P., McCombe, P.A. (Eds.), Autoimmune Neurological Disease, Cambridge University Press, Cambridge, pp. 26-88.
    • (1995) Autoimmune Neurological Disease , pp. 26-88
    • Pender, M.P.1
  • 36
    • 0025817888 scopus 로고
    • Apoptosis in the nervous system in experimental allergic encephalomyelitis
    • Pender M.P., Nguyen K.B., McCombe P.A., Kerr J.F. Apoptosis in the nervous system in experimental allergic encephalomyelitis. J. Neurol. Sci. 104:1991;81-87.
    • (1991) J. Neurol. Sci. , vol.104 , pp. 81-87
    • Pender, M.P.1    Nguyen, K.B.2    McCombe, P.A.3    Kerr, J.F.4
  • 37
    • 0026661264 scopus 로고
    • Apoptosis of αβ T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: Its possible implications for recovery and acquired tolerance
    • Pender M.P., McCombe P.A., Yoong G., Nguyen K.B. Apoptosis of αβ T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. J. Autoimmun. 5:1992;401-410.
    • (1992) J. Autoimmun. , vol.5 , pp. 401-410
    • Pender, M.P.1    McCombe, P.A.2    Yoong, G.3    Nguyen, K.B.4
  • 38
    • 0027284016 scopus 로고
    • Autoimmune gld mutation uncouples suicide and cytokine/ proliferation pathways in activated, mature T cells
    • Russell J.H., Wang R. Autoimmune gld mutation uncouples suicide and cytokine/ proliferation pathways in activated, mature T cells. Eur. J. Immunol. 23:1993;2379-2382.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2379-2382
    • Russell, J.H.1    Wang, R.2
  • 39
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell J.H., Rush B., Weaver C., Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA. 90:1993;4409-4413.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4409-4413
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 40
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M., Breitschopf H., Gold R., Zischler H., Rothe G., Wekerle H., Lassmann H. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. Am. J. Pathol. 143:1993;446-452.
    • (1993) Am. J. Pathol. , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 41
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T., Takahashi T., Golstein P., Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell. 75:1993;1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 43
    • 0029065604 scopus 로고
    • Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: Further evidence of apoptotic deletion of autoreactive T cells in the central nervous system
    • Tabi Z., McCombe P.A., Pender M.P. Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: further evidence of apoptotic deletion of autoreactive T cells in the central nervous system. Int. Immunol. 7:1995;967-973.
    • (1995) Int. Immunol. , vol.7 , pp. 967-973
    • Tabi, Z.1    McCombe, P.A.2    Pender, M.P.3
  • 44
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S., Sato T., Krajewski S., Kochel K., Irie S., Millan J.A., Reed J.C. Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell. 80:1995;279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 45
    • 0027386799 scopus 로고
    • Identification of rat TCRβ-V8.2, 8.5, and 10 gene products by monoclonal antibodies
    • Torres-Nagel N.E., Gold D.P., Hunig T. Identification of rat TCRβ-V8.2, 8.5, and 10 gene products by monoclonal antibodies. Immunogenetics. 37:1993;305-308.
    • (1993) Immunogenetics , vol.37 , pp. 305-308
    • Torres-Nagel, N.E.1    Gold, D.P.2    Hunig, T.3
  • 46
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • van Parijs L., Ibraghimov A., Abbas A.K. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity. 4:1996;321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 48
    • 0018423356 scopus 로고
    • Experimental allergic encephalomyelitis in the Lewis rat: Studies on the mechanism of recovery from disease and acquired resistance to reinduction
    • Willenborg D.O. Experimental allergic encephalomyelitis in the Lewis rat: studies on the mechanism of recovery from disease and acquired resistance to reinduction. J. Immunol. 123:1979;1145-1150.
    • (1979) J. Immunol. , vol.123 , pp. 1145-1150
    • Willenborg, D.O.1
  • 49
    • 0031587883 scopus 로고    scopus 로고
    • Daxx, a novel Fas-binding protein that activates JNK and apoptosis
    • Yang X., Khosravi-Far R., Chang H.Y., Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 89:1997;1067-1076.
    • (1997) Cell , vol.89 , pp. 1067-1076
    • Yang, X.1    Khosravi-Far, R.2    Chang, H.Y.3    Baltimore, D.4
  • 50
    • 0028226620 scopus 로고
    • Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes
    • Yoshino T., Kondo E., Cao L., Takahashi K., Hayashi K., Nomura S., Akagi T. Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes. Blood. 83:1994;1856-1861.
    • (1994) Blood , vol.83 , pp. 1856-1861
    • Yoshino, T.1    Kondo, E.2    Cao, L.3    Takahashi, K.4    Hayashi, K.5    Nomura, S.6    Akagi, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.