Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions

Cancer Research

Volumn 57, Issue 21, 1997, Pages 4882-4888

  Uría, José A ^a   Stahle Bäckdahl, Mona ^c   Seiki, Motoharu ^d   Fueyo, Antonio ^b   López Otín, Carlos ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b UNIVERSIDAD DE OVIEDO   (Spain)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE;

ARTHRITIS; ARTICLE; ARTICULAR CARTILAGE; BREAST CARCINOMA; CELL INTERACTION; COCULTURE; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STROMA; STROMA CELL; TUMOR GROWTH;

EID: 0040351696     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Woessner, J. F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J., 5: 2145-2154, 1991.
2. Matrisian, L. M. The matrix degrading metalloproteinases. BioEssays, 14: 455-463, 1992.
3. Birkedal-Hansel, H., Moore, W. G. Y., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A., and Engler, J. A. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med., 4: 197-250, 1993.
4. Stetler-Stevenson, W. G., Aznavoorian, S., and Liotta, L. A. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol., 9: 541-573, 1993.
5. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamolo, E., and Seiki, M. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (Lond.), 370: 61-65, 1994.
6. Puente, X. S., Pendás, A. M., Llano, E., Velasco, G., and Lopez-Otin, C. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res., 56: 944-949, 1996.
7. Belaaouaj, A., Shipley, J. M., Kobayashy, D. K., Zimonjic, D. B., Popescu, N., Silverman, G. A., and Shapiro, S. D. Human macrophage metalloelastase: genomic organization, chromosomal location, gene linkage and tissue-specific expression. J. Biol. Chem., 270: 14568-14575, 1995.
8. Basset, P., Bellocq, J. P., Wolf, C. Stoll, Y., Hutin, P., Limacher, J. M., Podhajcer, O. L., Chenard, M. P., Rio, M. C., and Chainhon, P. A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (Lond.), 348: 699-704, 1990.
9. Pendás, A. M., Knäuper, V., Puente, X. S., Llano, E., Mattel, M. G., Apte, S., Murphy, G., and Lopez-Otin, C. Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location and tissue distribution. J. Biol. Chem., 272: 4281-4286, 1997.
10. Freije, J. P., Diez-Itza, I., Balbín, M., Sinchez, L. M., Blasco, R., Tolivia, J., and López-Otín, C. Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J. Biol. Chem., 269: 16766-16773, 1994.
11. Pendás, A. M., Matilla, T., Estivill, X., and López-Otín, C. The human collagenase-3 (CLG3) gene is located on chromosome 11q22.3 clustered to other members of the matrix metalloproteinase gene family. Genomics, 26: 615-618, 1995.
12. Knauper, V., López-Otín, C., Smith, B., Knight, G., and Murphy, G. Biochemical characterization of human collagenase-3. J. Biol. Chem., 271: 1544-1550, 1996.
13. Stahle-Bäckdahl, M., Sandsted, B., Bruce, K., Lindahl, A., Jiménez, M. G., Vega, J. A., and López-Otín, C. Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis. Lab. Invest., 76: 717-728, 1997.
14. Mitchell, P. G., Magna, H. A., Reeves, L. M., Lopresti-Morrow, L. L., Yocum, V. A., Rosner, P. J., Geogheaan, K. F., and Hambor, J. E. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J. Clin. Invest., 97: 761-768, 1996.
15. Reboul, P., Pelletier, J. P., Tardif, G., Cloutier, J. M., and Martel-Pelletier, J. The new collagenase collagenase-3. is expressed and synthesized by human chondrocytes but not by synoviocytes. J. Clin. Invest., 97: 2011-2019, 1996.
16. Wernicke, D., Seyfert, C., Hinzmann, B., and Gromnica-Ihle, E. Cloning of collagenase-3 from the synovial membrane and its expression in rheumatoid arthritis and osteoarthritis. J. Rheumatol., 23: 590-595, 1996.
17. Lindy O., Konttinen, Y. T., Sorsa, T., Ding, Y., Santavirta, S., Ceponis, A., and López-Otín C. MMP-13 (collagenase-3) in human rheumatoid synovium. Arthritis Rheum., 40: 1391-1399, 1997.
18. Fosang, A. J., Last K., Knauper, V., Murphy, G., and Neame, P. J. Degradation of cartilage aggrecan by collagenase-3 (MMP-13). FEBS Lett., 380: 17-20, 1996.
19. Knäuper, V., Cowell, S., Smith, B., López-Otín, C., O'Shea, M., Morris, H., Zardi, L., and Murphy, G. The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction. J. Biol. Chem., 272: 17124-17131, 1997.
20. Knauper, V., Will, H., López-Otín, C., Smith, B., Atkinson, S. J., Stanton, H., Hembry, R., and Murphy, G. Cellular mechanisms for human procollagenase-3 (MMP-13) activation: evidence that MTI-MMP (MMP-14) and gelatinase A (MMP-2) are able to generate active enzyme. J. Biol. Chem., 277: 17124-17131, 1996.
21. Bloom, H. J. G., and Richardson, W. W. Histological grading and prognosis in breast cancer. Br. J. Cancer, 11: 359-377, 1957.
22. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorotorm extraction. Anal. Biochem., 162: 156-159, 1987.
23. Stahle-Bäckdahl, M., Sudbeck, B. D., Eisen, A. Z., Welgus, H. G., and Parks, W. C. Expression of 92-kDa type IV collagenase in eosinophils associated with basal cell carcinoma. J. Invest. Dermatol., 99: 497-503, 1992.
24. Biswas, C. Matrix influence on the tumor cell stimulation of fibroblast collagenase production. J. Cell. Biochem. 28: 39-45, 1985.
25. Kataoka, H., DeCastro, R., Zucker, S., and Biswas, C. Tumor cell-denved collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin. and 72-kDa gelatinase. Cancer Res., 53: 3154-3158, 1993.
26. Wolf, C., Rouyer, N., Lutz, Y., Adida, C., Loriot, M., Bellocq, J. P., Chambon, P., and Basset, P. Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc. Natl. Acad. Sci. USA, 90: 1843-1847, 1993.
27. Canete-Soler, R., Litzky, L., Lubensky, I., and Muschel, R. J. Localization of the 92 kD gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization. Am. J. Pathol., 144: 518-527, 1994.
28. Himelstein, B. P., Canete-Soler, R., Bernhard, E. J., and Muschel, R. J. Induction of fibroblast 92 kDa selatinase/type IV collagenase expression by direct contact with metastatic tumor cells. J. Cell Sci., 107: 477-486, 1994.
29. r 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts. Cancer Res., 55: 963-967, 1995.
30. Schnack Nielsen, B., Sehested, M., Timshel, S., Pyke, C., and Dano, K. Messenger RNA for urokinase plasminogen activator is expressed in myofibroblasts adjacent to cancer cells in human breast cancer. Lab. Invest., 74: 168-177, 1996.
31. MacDougall, J. R., and Matrisian, L. M. Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis. Cancer Metastasis Rev., 14: 351-362, 1995.
32. Borchers, A. H., Powell, M. B., Fusening, N. E., and Bowden, T. Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures. Exp. Cell Res., 213: 143-147, 1994.
33. Okada, A., Bellocq, I. P., Rouyer, N., Chenard, M. P., Rio, M. C., Chambon, P., and Basset, P. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast and head and neck carcinomas. Proc. Natl. Acad. Sci. USA, 92: 2730-2734, 1995.
34. Soini, Y., Hurskainen, T., Höyhtyä, M., Oikarinen, A., and Autio-Harmainen, H. 72 kDa and 92 kDa type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization. J. Histochem. Cytochem., 42: 945-951, 1994.
35. Omura, T. H., Noguchi, A., Johanns, C. A., Jeffrey, I. J., and Partridge, N. C. Identification of a specific receptor for interstitial collagenase on osteoblastic cells. J. Biol. Chem., 269: 24994-24998, 1994.
36. Monteagudo, C. Merino, M. J., San-Juan, J., Liotta, L., and Stetler-Stevenson, W. G. Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. Am. J. Pathol., 136: 585-592, 1990.
37. Höyhtyä M., Fridman, R., Komarek, D., Porter-Jordan, K., Stetler-Stevenson, W. G., Liotta, L. A. and Liang, C. M. Immunohistochemical localization of matrix metalloproteinase-2 and its specific inhibitor TIMP 2 in neoplastic tissues with monoclonal antibodies. Int. J. Cancer, 56: 500-505, 1994.
38. Heppner, K. J., Matrisian, L. M., Jensen, R. A., and Rodgers, W. H. Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am. J. Pathol., 149: 273-282, 1996.
39. Wright, J. H., McDonnell, S., Portella, G., Bowden, G. T., Balmain, A., and Matrisian, L. M. A switch from stromal to tumor cell expression of stromelysm-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Mol. Carcinog., 10: 207-215, 1994.
40. Yao, Y., Jin, L., Fuchs, A., Joseph, A., Hastings, H. M., Goldberg, I. D., and Rosen, E. M. Scatter factor protein levels in human cancers. Am. J. Pathol., 149: 1707-1717, 1996.
41. Vidal-Vanaclocha, F., Alvarez, A., Asumendi, A., Urcelay, B., Tonino, P., and Dinarello, C. A. Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo: increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro. J. Natl. Cancer Inst. (Bethesda), 88: 198-205, 1996.
42. Nguyen, M., Corless, C. L., Kräling, B. M., Tran, C., Atha, T., Bischoff, J., and Barsky, S. H. Vascular expression of E-selectin is increased in estrogen-receptor-negative breast cancer. Am. J. Pathol., 150: 1307-1314, 1997.
43. Wilcox, B. D., Dumin, J. A., and Jeffrey, J. J. Serotonin regulation of interleukin-1 messenger RNA in rat uterine smooth muscle cells: relationship to the production of interstitial collagenase. J. Biol. Chem., 269: 29658-29664, 1994.
44. Borden, P., Solymar, D., Swcharczuk, A., Lindman, B., Cannon, P., and Heller, R. A. Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes. J. Biol. Chem., 277: 23577-23581, 1996.
45. Pendás, A. M., Balbin, M., Llano, E., Jiménez, M. G., and López-Otín, C. Structural analysis and promoter characterization of the human collagenase-3 gene (MMP-13). Genomics, 40: 222-233, 1997.