Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds

Journal of Investigative Dermatology

Volumn 109, Issue 1, 1997, Pages 96-101

  Vaalamo, Maarit ^a   Mattila, Laura ^b   Johansson, Nina ^b   Kariniemi, Arja Leena ^a   Karjalainen Lindsberg, Marja Liisa ^c   Kähäri, Veli Matti ^b   Saarialho Kere, Ulpu ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Fibroblast; Metalloproteinase; Wound healing

Indexed keywords

COLLAGENASE; MATRIX METALLOPROTEINASE; STROMELYSIN;

ARTICLE; CELL POPULATION; CHRONIC VEIN INSUFFICIENCY; CONTROLLED STUDY; EPITHELIZATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKIN ULCER; STROMA CELL; WOUND HEALING;

EID: 0030740249     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12276722     Document Type: Article

References (37)

1. Agren MS: Gelatinase activity during wound healing. Br J Dermatol 131:634-640, 1994
2. Birkedal-Hansen H: Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7:728-735, 1995
3. Campbell EJ, Cury JD, Shapiro SD, Goldberg GI, Welgus HG: Neutral proteinases of human mononuclear phagocytes. Cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases. J Immunol 146:1286-1293, 1991
4. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
5. Clark RAF: Wound repair. In: Clark RAF (ed.). The Molecular and Cellular Biology of Wound Repair. 2nd ed. Plenum Press, New York, 1995, pp 3-35
6. Eckes B, Aumailley M, Krieg T: Collagens and the reestablishment of dermal integrity. In: Clark RAF (ed.). The Molecular and Cellular Biology of Wound Repair. 2nd ed. Plenum Press, New York, 1996, pp 493-512
7. Freije JMP, Diez-Itza I, Balbin M, Sanchez LM, Blasco R, Tolivia J, Lopez-Otin C: Molecular cloning of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem 269:16766-16773, 1994
8. Goldberg GI, Wilhelm SM, Kronberger A, Bauer EA, Grant GA, Eisen AZ: Human fibroblast collagenase: complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem 261:6600-6605, 1986
9. Johansson N, Saarialho-Kere UK, Airola K, Herva R, Nissinen L, Westermarck J, Vuorio E, Heino J, Kähäri VM: Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during fetal bone development. Dev Dyn 28:387-395, 1997a
10. Johansson N, Westermarck J, Leppä S, Häkkinen L, Koivisto L, Lopez-Otin C, Peltonen J, Heino J, Kähäri V-M: Collagenase-3 (MMP-13) gene expression by HaCat keratinocytes is enhanced by tumor necrosis factor-α and transforming growth factor-β. Cell Growth Differ 8:243-250, 1997b
11. Knäuper V, Lopez-Otin C, Smith B, Knight G, Murphy G: Biochemical characterization of human collagenase-3. J Biol Chem 271:1544-1550, 1996
12. Mauch C, Adelmann-Grill B, Hatamochi A, Krieg T: Collagenase gene expression in fibroblasts is regulated by a 3-dimensional contact with collagen. FEBS Lett 250:301-305, 1989
13. Mauviel A, Chung K-Y, Agarwal A, Tamai K, Uitto J: Cell-specific induction of distinct oncogenes of the jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-β in fibroblasts and keratinocytes. J Biol Chem 271:10917-10923, 1996
14. Mignatti P, Rifkin DB, Welgus HG, Parks WC: Proteinases and tissue remodeling. In: Clark RAF (ed.). The Molecular and Cellular Biology of Wound Repair. 2nd ed. Plenum Press, New York, 1996, pp 427-474
15. Mitchell PG, Magna HA, Reeves LM, Lopresti-Morrow LL, Yocum SA, Rosner PJ, Geoghegan KF, Hambor JE: Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 97:761-768, 1996
16. Prosser IW, Stenmark KR, Suthar M, Crouch EC, Mecham RP, Parks WC: Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization. Am J Pathol 135:1073-1088, 1989
17. Pulford KAF, Rigney EM, Micklem KJ, Stross WP, Gatter KC, Mason DY: KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol 42:414-421, 1989
18. Reboul P, Pelletier J-P, Tardif G, Cloutier J-M, Martel-Pelletier J: The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes and synoviocytes. J Clin Invest 97:2011-2019, 1996
19. Riikonen T, Westermarck J, Koivisto L, Broberg A, Kähäri V-M, Heino J: Integrin α1β1 is a positive regulator of collagenase (MMP-1) and collagen α1(I) gene expression. J Biol Chem 270:13548-13552, 1995
20. Roberts AB, Sporn MB: Transforming growth factor-β. In: Clark RAF (ed.). The Molecular and Cellular Biology of Wound Repair. 2nd ed. Plenum Press, New York, 1995, pp 275-308
21. Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC: Distinct localization of collagenase and TIMP expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest 90:1952-1957, 1992
22. Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC: Expression of interstitial collagenase, 92 kDa gelatinase, and TIMP-1 in granuloma annulare and necrobiosis lipoidica diabeticorum. J Invest Dermatol 100:335-342, 1993a
23. Saarialho-Kere UK, Kovacs SO, Pentland AP, Olerud JE, Welgus HG, Parks WC: Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J Clin Invest 92:2858-2866, 1993b
24. Saarialho-Kere UK, Pentland AP, Birkedal-Hansen H, Parks WC, Welgus HG: Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest 94:79-88, 1994
25. Saarialho-Kere UK, Vaalamo M, Puolakkainen P, Airola K, Parks WC, Karjalainen-Lindsberg M-L: Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol 148:519-526, 1996
26. Saarialho-Kere UK, Welgus HG, Parks WC: Divergent mechanisms regulate interstitial collagenase and 92 kDa gelatinase by endotoxin in monocytic-like cells. J Biol Chem 268:17354-17361, 1993c
27. Salo T, Mäkelä M, Kylmäniemi M, Autio-Harmainen H, Larjava H: Expression of matrix metalloproteinase-2 and -9 during early human wound healing. Lab Invest 70:176-182, 1994
28. Scharffetter K, Kulozik M, Stolz W, Lankat-Buttergereit B, Hatamochi A, Söhnchen R, Krieg T: Localization of collagen α1(I) gene expression during wound healing by in situ hybridization. J Invest Dermatol 93:405-412, 1989
29. Sudbeck BS, Parks WC, Welgus HG, Pentland AP: Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities. J Biol Chem 269:30022-30029, 1994
30. Thomas PS: Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci USA 77:5201-5205, 1980
31. Vaalamo M, Weckroth M, Puolakkainen P, Saarinen P, Kere J, Lauharanta J, Saarialho-Kere UK: Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds. Br J Dermatol 135:52-59, 1996
32. Welgus HG, Jeffrey JJ, Eisen AZ: The collagen substrate specificity of human skin fibroblast collagenase. J Biol Chem 256:9511-9515, 1981
33. Werb Z: Proteinases and matrix degradation. In: Kelley WN, Harris ED, Ruddy S, Sledge CB (eds.). Textbook of Rheumatology. WB Saunders, Philadelphia, 1989, pp 300-326
34. Werb Z, Hembry RM, Murphy G, Aggeler J: Commitment to expression of the metalloendopeptidases collagenase and stromelysin: relationship of inducing events to changes in cytoskeletal architecture. J Cell Biol 102:697-702, 1986
35. Wernicke D, Seyfert C, Hinzmann B, Gromnica-Ihle E: Cloning of collagenase-3 from the synovial membrane and its expression in rheumatoid arthritis and osteoarthritis. J Rheumatol 23:590-595, 1996
36. Wilhelm SM, Collier IE, Kronberger A, Eisen AZ, Marmer BL, Grant GA, Bauer EA, Goldberg GI: Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci USA 84:6725-6729, 1987
37. Woessner JF: The family of matrix metalloproteinases. Ann NY Acad Sci 732:11-21, 1994