Anti-DNA and autoantibodies

Current Opinion in Rheumatology

Volumn 12, Issue 5, 2000, Pages 364-368

  Pisetsky, David S ^a,b,c,d  

^a Department of Medicine and Immunology ^*  (United States)

^b Division Rheumatology Allergy and Clinical Immunology   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d DURHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; DNA ANTIBODY;

ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN BINDING; HUMAN; IMMUNOGENICITY; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PRIORITY JOURNAL; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; DNA; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE;

EID: 0033840297     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002281-200009000-00002     Document Type: Review

References (36)

1. Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
2. Antibody responses to DNA in normal immunity and aberrant immunity
3. Biology of disease. Nephritogenic autoantibodies in systemic lupus erythematosus: Immunochemical properties, mechanisms of immune deposition, and genetic origins
4. Receptor editing, immune diversification, and self-tolerance
5. Editing disease-associated autoantibodies
6. Characterization of anti-DNA B cells that escape negative selection
7. MRL-Ipr/Ipr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
8. Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/Ipr mice
9. Genetic dissection of lupus pathogenesis a recipe for nephrophilic autoantibodies
10. Control of separate pathogenic autoantibody responses marks MHC gene contributions to murine lupus
11. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
12. Geneti, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis
13. Production of high affinity autoantibodies in autoimmune New Zealand black/New Zealand white F1 mice targeted with an anti-DNA heavy chain
14. The importance of the light chain for the epitope specificity of human anti-U1 small nuclear RNA autoantibodies present in systemic lupus erythematosus patients
15. Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice
16. Side-chain specificities and molecular modelling of peptide determinants for two anti-Sm B/B' autoantibodies
17. DNA binding by the VH domain of anti-Z-DNA antibody and its modulation by association of the VL domain
18. Molecular mimicry between bacterial and self antigen in a patient with systemic lupus erythematosus
19. Specificity of antibodies to bacterial DNA in the sera of healthy human subjects and patients with systemic lupus erythematosus
20. Apoptosis: The importance of being eaten
21. Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus relations with disease activity, antibodies to double stranded DNA, and neutropenia
22. Dendritic cell presentation of antigens from apoptotic cells in a proinflammatory context Role of opsonizing anti- β2-glycoprotein I antibodies
23. Cleavage by granzyme B is strongly predictive of autoantigen status: Implications for initiation of autoimmunity
24. Immunization of mice with human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse
25. Immune responses to Ro60 and its peptides in mice I. The nature of the immunogen and endogenous autoantigen determine the specificities of the induced autoantibodies
26. Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B)
27. Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies
28. Strong association of autoantibodies to human nuclear lamin B1 with lupus anticoagulant antibodies in systemic lupus erythematosus
29. DNA levels in circulating immune complexes decrease at severe SLE flares: Correlation with complement component C1q
30. Anti-DNA and anti-nucleosome antibody affinity-a mirror image of lupus nephritis?
31. Multicenter validation of recombinant, natural and synthetic antigens used in a single multiparameter assay for the detection of specific anti-nuclear autoantibodies in connective tissue disorders
32. Screening tests for antinuclear antibodies (ANA): Selective use of central nuclear antigens as a rational basis for screening by ELISA
33. A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities
34. The distribution of antinuclear antibody titers in 'normal' children and adults
35. The prognosis and outcome of patients referred to an outpatient clinic for rheumatic diseases characterized by the presence of antinuclear antibodies (ANA)
36. Fluctuation of anti-Ro/SS-A antibody levels in patients with systemic lupus erythematosus and Sjogren's syndrome: A prospective study