Strong association of autoantibodies to human nuclear lamin B1 with lupus anticoagulant antibodies in systemic lupus erythematosus

Arthritis and Rheumatism

Volumn 42, Issue 7, 1999, Pages 1347-1353

  Senécal, Jean Luc ^a   Rauch, Joyce ^b   Grodzicky, Tamara ^a   Raynauld, Jean Pierre ^a   Uthman, Imad ^a   Nava, Arnulfo ^a   Guimond, Martin ^a   Raymond, Yves ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; LAMIN B; LUPUS ANTICOAGULANT;

ADULT; AGED; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; BLOOD SAMPLING; CROSS REACTION; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REGRESSION ANALYSIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0342471749     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199907)42:7<1347::aid-anr7>3.0.co;2-%23     Document Type: Article

References (20)

1. Guilty MN, Danon F, Brouet JC, Bornens M, Courvalin JC. Autoantibodies to nuclear lamin B in a patient with thrombocytopenia. Eur J Cell Biol 1987;43:266-72.
2. Reeves WH, Chaudhary N, Salerno A, Blobel G. Lamin B autoantibodies in sera of certain patients with systemic lupus erythematosus. J Exp Med 1987;165:750-62.
3. Lassoued K, Guilly MN, Danon F, André C, Dhumeaux D, Clauvel JP, et al. Antinuclear autoantibodies specific for lamins: characterization and clinical significance. Ann Intern Med 1988; 108:829-33.
4. Reeves WH, Ali SA. Preferential use of AL chain in lamin B autoantibodies. J Immunol 1989;143:3614-18.
5. Chou CH, Ali SA, Roubey R, Buyon J, Reeves WH. Onset and regulation of anti-lamin B autoantibody production is independent of the level of polyclonal activation. Autoimmunity 1991;8:297-305.
6. Senécal JL, Raymond Y. Autoantibodies to DNA, lamins, and pore complex proteins produce distinct peripheral fluorescent antinuclear antibody patterns on the HEp-2 substrate [letter]. Arthritis Rheum 1991;34:249-51.
7. Senécal JL, Raymond Y. Autoantibodies to major and minor nuclear lamins are not restricted to autoimmune diseases. Clin Immunol Immunopathol 1992;2:115-25.
8. 2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus. Arthritis Rheum 1996;39:1466-74.
9. Sammaritano LR, Ng S, Sobel R, Lo KS, Simantov R, Furie R, et al. Anticardiolipin IgG subclasses: association of IgG2 with arterial and/or venous thrombosis. Arthritis Rheum 1997;40:1998-2006.
10. Pollard KM, Chan EKL, Grant BJ, Sullivan KF, Tan EM, Glass CA. In vitro posttranslational modification of lamin B cloned from a human T-cell line. Mol Cel Biol 1990;10:2164-75.
11. Studier FW, Rosenberg AH, Dunn JJ, Dubendorff JW. Use of T7 polymerase to direct expression of cloned genes. Methods Enzymol 1990;185:60-89.
12. Heitlinger E, Peter M, Häner M, Lustig A, Aebi U, Nigg EA. Expression of chicken lamin B2 in Escherichia coli: characterization of its structure, assembly and molecular interactions. J Cell Biol 1991;113:485-95.
13. Gagnon G, Sasseville AMJ, Raymond Y. Preparative 2-D electrophoresis system purifies recombinant nuclear proteins from whole bacterial lysates. Bio Rad US/EG Bull 1992;1773.
14. Price BE, Rauch J, Shia MA, Walsh MT, Lieberthal W, Gilligan HM, et al. Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a β2-glycoprotein I-dependent manner. J Immunol 1996;157:2201-8.
15. Godfrey K. Comparing the means of several groups. In: Bailar JC III, Mosteller F, editors. Medical uses of statistics. Waltham (MA): NEJM Books; 1986. p. 205-34.
16. Horbach DA, von Oort E, Donders RCJM, Derksan RHWM, de Groot PG. Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Thromb Haemost 1996;76:916-24.
17. Asherson RA, Cervera R, Piette JC, Shoenfeld Y. The antiphospholipid syndrome: history, definition, classification, and differential diagnosis. In: Asherson RA, Cervera R, Piette JC, Shoenfeld Y, editors. The antiphospholipid syndrome. Boca Raton (FL): CRC Press; 1996. p. 3-12.
18. Senécal J-L, Raymond Y. Are there subsets of autoantibodies to nuclear lamins? [letter]. Arthritis Rheum 1992;35:1407-8.
19. Senécal J-L, Ichiki S, Girard D, Raymond Y. Autoantibodies to nuclear lamins and to intermediate filament proteins: natural, pathologic or pathogenic? J Rheumatol 1993;20:211-9.
20. Von Mikecz A, Konstantinov K, Buchwald DS, Gerace L, Tan EM. High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis Rheum 1997;40:295-305.