Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis

Development

Volumn 127, Issue 17, 2000, Pages 3865-3876

  Rones, M S ^a   McLaughlin, K A ^a   Raffin, M ^a   Mercola, M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Heart; Mesocardium; Myocardium; Notch; Serrate; Xenopus

Indexed keywords

HOMEODOMAIN PROTEIN; LIGAND; PROTEIN NOTCH; PROTEIN SERRATE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FATE; CELL TYPE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE; MESODERM; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; PERICARDIUM; PRECURSOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; XENOPUS;

ANIMAL; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; MEMBRANE PROTEINS; MYOCARDIUM; SIGNAL TRANSDUCTION; SUPPORT, U.S. GOV'T, P.H.S.; XENOPUS;

EID: 0033835494     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (85)

1. Notch signaling
2. Notch signaling: Cell fate control and signal transduction in development
3. Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch
4. Transient and restricted expression during mouse embryogenesis of DIII, a murine gene closely related to Drosophila Delta
5. A zebrafish homologue of the Drosophila neurogenic gene Notch and its pattern of transcription during early embryogenesis
6. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta
7. Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in Xenopus embryos
8. Control of neurogenesis - Lessons from frogs, fish, and flies
9. Xotch, the Xenopus homolog of Drosophila notch
10. The fate diversity of mesodermal cells within the heart field during chicken early embryogenesis
11. Notchl is required for the coordinate segmentation of somites
12. Experiments on the development of the heart of Amblystoma punctatum
13. A role for the Drosophila neurogenic genes in mesoderm differentiation
14. Delta-1 negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation
15. Conservation of the notch signaling pathway in mammalian neurogenesis
16. Correlating notch signaling with thymocyte maturation
17. Regualation of neuronal diversity in the Xenopus retina by delta signaling
18. Xotch inhibits cell differentiation in the Xenopus retina
19. Cardiac troponin I is a heart-specific marker in the Xenopus embryo: Expression during abnormal heart morphogenesis
20. Mouse Dll3: A novel divergent delta gene which may complement the function of other delta homologues during early pattern formation in the mouse embryo
21. Experimentelle Beitrge zur Herzentwicklung der Amphibien
22. The human homolog of the Drosophila notch gene is broken by chromosomal translocations in T lymphoblastic neoplasms
23. Fashioning the vertebrate heart: Earliest embryonic decisions
24. Expression pattern of motch, a mouse homolog of Drasophila notch, suggests an important role in early post-implantation mouse development
25. Vertebrate tinman homologues XNkx2.3 and XNkx2.5 are required for heart formation in a functionally redundant manner
26. Multiple roles for notch in Drosophila myogenesis
27. Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, Nkx2.3 and Nkx2.5
28. Delta-notch signaling and the patterning of sensory cell differentiation in the zebrafish ear: Evidence from the mind bomb mutant
29. In situ hybridization: An improved whole mount method for Xenopus embryos
30. The function of the neurogenic genes during epithelial development in the Drosophila embryo
31. Expression of a Delta homologue in prospective neurons in the chick
32. Maintenance of somite borders in mice requires the Delta homologue Dlll
33. Fringe, notch, and making developmental boundaries
34. Heart induction in salamanders
35. Protective effects of notch-1 on TCR-induced apoptosis
36. Periodic repression of notch pathway genes governs the segmentation of Xenopus embryos
37. The notch ligand, X-Delta, mediates segmentation of the paraxial mesoderm in Xenopus embryos
38. The Xenopus GATA 4,5,6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis
39. Notch3 mutations in CADASIL, a hereditary adult onset condition causing stroke and dementia
40. Efficient hormone-inducible protein function in Xenopus laevis
41. Alagille syndrome
42. The novel notch homologue mouse notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium
43. Cardiovascular development in the zebrafish: Endocardial progenitors are sequestered within the heart field
44. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
45. Jagged: A mammalian ligand that activates Notch1
46. Induction of cardiac muscle differentiation in isolated animal pole explants of Xenopus laevis embryos
47. The Notch1 receptor is cleaved constituitively by a furin-like convertase
48. Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm
49. Vertebrate heart development
50. Suppressor of hairless independent events in notch signaling imply novel pathway elements
51. Early steps in vertebrate cardiogenesis
52. Cell type-specific activation of actin genes in the early amphibian embryo
53. A chick homologue of serrate and its relationship with notch and delta homologues during central neurogenesis
54. An inductive role for the endoderm in Xenopus cardiogenesis
55. Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos
56. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
57. Mutations in the human Jagged1 gene are responsible for Alagille syndrome
58. Disruption of the mouse RBP-Jk results in early embryonic death
59. Subdivision of the cardiac Nkx2.5 expression domain into myogenic and non-myogenic compartments
60. Expression analysis of a Notch homologue in the mouse embryo
61. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
62. The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis
63. The specification of heart mesoderm occurs during gastrulation in Xenopus laevis
64. The restriction of the heart morphogenetic field in Xenopus laevis
65. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
66. A role for bone morphogenetic proteins in the induction of cardiac myogenesis
67. Induction of avian cardiac myogenesis by anterior endoderm
68. Regulation in the heart field of zebrafish
69. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
70. Jagged2: A Serrate-like gene expressed during rat embryogenesis
71. Notch signaling inhibits muscle cell differentiation through a CBF1 independent pathway
72. Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds
73. Notch is essential for postimplantation development in mice
74. XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development
75. Notch4/int-3, a mammalian proto-oncogene, is an endothelial cell-specific mammalian Notch gene
76. Notch receptor activation inhibits oligodendrocyte differentiation
77. The ins and outs of notch signaling
78. Notch signaling: Direct or what?
79. A homolog of Drosophila notch expressed during mammalian development
80. Notch2: A second mammalian notch gene
81. Three novel notch genes in zebrafish: Implications for vertebrate notch gene evolution and function
82. The Xenopus homolog of Drosophila suppressor of hairless mediates notch signaling during primary neurogenesis
83. Complementary and combinatorial patterns of notch gene family expression during early mouse development
84. Activated notch inhibits myogenic activity of the MADS-box transcription factor myocyte enhancer factor 2c