Do unintended antisense transcripts contribute to sense cosuppression in plants (multiple letters)

Trends in Genetics

Volumn 15, Issue 1, 1999, Pages 11-12

  Jorgensen, Richard A ^a   Que, Qiudeng ^a   Stam, Maike ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION REGULATION; GENE LOCUS; LETTER; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC PLANT;

ACYLTRANSFERASES; GENE EXPRESSION REGULATION, PLANT; KANAMYCIN RESISTANCE; OLIGONUCLEOTIDES, ANTISENSE; PLANT PROTEINS; PLANTS; RECOMBINANT FUSION PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, DOUBLE-STRANDED; RNA, MESSENGER; RNA, PLANT; TEMPLATES, GENETIC; TRANSGENES;

EID: 0032946410     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(98)01651-5     Document Type: Letter

References (14)

1. Montgomery M.K., Fire A. Double-stranded RNA as a mediator in sequence-specific genetic silencing and cosuppression. Trends Genet. 14:1998;255-258.
2. Grierson D.et al. Does co-suppression of sense genes in transgenic plants involve antisense RNA? Trends Biotechnol. 9:1991;122-123.
3. Que Q.et al. Disease resistance conferred by expression of a gene encoding H2O2-generating glucose oxidase in transgenic potato plants. Plant Cell. 9:1997;1357-1368.
4. Que Q., Jorgensen R.A. Homology-based control of gene expression patterns in transgenic petunia flowers. Dev. Genet. 22:1998;100-109.
5. Jorgensen R.A.et al. Chalcone synthase co-suppression phenotypes in petunia flowers: comparison of sense vs. antisense constructs and single-copy vs. complex T-DNA sequences. Plant Mol. Biol. 31:1996;957-973.
6. Que Q.et al. Distinct patterns of pigment suppression are produced by allelic sense and antisense chalcone synthase transgenes in petunia flowers. Plant J. 13:1998;401-409.
7. van Blokland R.et al. Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover. Plant J. 6:1994;861-877.
8. Stam M.et al. Post-transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats. Plant J. 12:1997;63-82.
9. Stam M.et al. Position-dependent methylation and transcriptional silencing of transgenes in inverted T-DNA repeats: implications for posttranscriptional silencing of homologous host genes in plants. Mol. Cell. Biol. 18:1998;6165-6177.
10. Dougherty W.G., Parks T.D. Transgenes and gene suppression: telling us something new? Curr. Opin. Cell Biol. 7:1995;399-405.
11. Wassenegger M., Pellissier T. A model for RNA-mediated gene silencing in higher plants. Plant Mol. Biol. 37:1998;349-362.
12. Ruiz M.T.et al. Initiation and maintenance of virus-induced gene silencing. Plant Cell. 10:1998;937-946.
13. Palauqui J.C.et al. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16:1997;4738-4745.
14. Jorgensen R.A.et al. An RNA-based information superhighway in plants. Science. 279:1998;1486-1487.