Zn2+ inhibits α-ketoglutarate-stimulated mitochondrial respiration and the isolated α-ketoglutarate dehydrogenase complex

Journal of Biological Chemistry

Volumn 275, Issue 18, 2000, Pages 13441-13447

  Brown, Abraham M ^a,b   Kristal, Bruce S ^a,b   Effron, Michelle S ^a   Shestopalov, Alexander I ^a   Ullucci, Paul A ^c   Sheu, K F Rex ^a,b   Blass, John P ^a,b   Cooper, Arthur J L ^a,b  

^a BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c ESA Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; GLUTAMATE DEHYDROGENASE; MALATE DEHYDROGENASE; OXOGLUTARATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; ZINC; ALPHA-KETOGLUTARIC ACID;

ANIMAL TISSUE; ARTICLE; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME METABOLISM; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; ANIMAL; DRUG EFFECT; ELECTRON TRANSPORT; ENZYME ACTIVATION; METABOLISM;

ANIMALS; ELECTRON TRANSPORT; ENZYME ACTIVATION; KETOGLUTARATE DEHYDROGENASE COMPLEX; KETOGLUTARIC ACIDS; MITOCHONDRIA, LIVER; RATS; ZINC;

EID: 0034607467     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.18.13441     Document Type: Article

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