A role for the SHP-2 tyrosine phosphatase in nerve growth factor- induced PC12 cell differentiation

Molecular Biology of the Cell

Volumn 8, Issue 8, 1997, Pages 1575-1585

  Wright, Jocelyn H ^a   Drueckes, Peter ^a   Bartoe, Joseph ^a   Zhao, Zhizhuang ^b   Shen, Shi Hsiang ^c   Krebs, Edwin G ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; NERVE GROWTH FACTOR; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; GENE OVEREXPRESSION; HORMONE ACTION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030929989     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.8.1575     Document Type: Article

References (63)

1. Ahmad, S., Banville, D., Zhao, Z., Fischer, E.H., and Shen, S.-H. (1993). A widely expressed human protein-tyrosine phosphatase containing SRC homology domains. Proc. Natl. Acad. Sci. USA 90, 2197-2201.
2. Alema, S., Casalbore, P., Agostini, E., and Tato, F. (1985). Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene. Nature 316, 557-559.
3. Allard, J.D., Chang, H.C., Herbst, R., McNeill, H., and Simon, M.A. (1996). The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1, and Raf. Development 122, 1125-1135.
4. Banville, D., Stocco, R., and Shen, S.H. (1995). Human protein tyrosine phosphatase 1C (PTPN6) gene structure: alternate promoter usage and exon skipping generate multiple transcripts. Genomics 27, 165-173.
5. Bazenet, C.E., Gelderloos, J.A., and Kazlauskas, A. (1996). Phosphorylation of tyrosine 720 in the platlet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation. Mol. Cell. Biol. 16, 6926-6936.
6. Bennett, A.M., Hausdorff, S.F., O'Reilly, A.M., Freeman, J.R.M., and Neel, B.C. (1996). Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol. Cell. Biol. 16, 1189-1202.
7. Bennett, A.M., Tang, T.L., Sugimoto, S., Walsh, C.T., and Neel, B.C. (1994). Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor β to Ras. Proc. Natl. Acad. Sci. USA 91, 7335-7339.
8. Bignon, J.S., and Siminovitch, K.A. (1994). Identification of PTP1C mutation as the genetic defect in motheaten and viable motheaten mice: a step toward defining the roles of protein tyrosine phosphatases in the regulation of hemopoietic cell differentiation and function. Clin. Immunol. Immunopathol. 73, 168-179.
9. Bouchard, P., Zhao, Z., Banville, D., Dumas, F., Fischer, E.H., and Shen, S.-H. (1994). Phosphorylation and identification of a major tyrosine phosphorylation site in the protein tyrosine phosphatase 1C. J. Biol. Chem. 269, 19585-19589.
10. Chamberlain, N.L., Driver, E.D., and Miesfeld, R.L. (1994). The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res. 22, 3181-3186.
11. Cossette, L.J., Hoglinger, O., Mou, L., and Shen, S.H. (1996). Localization and down-regulating role of the protein tyrosine phosphatase PTP2C in membrane ruffles of PDGF-stimulated cells. Exp. Cell Res. 223, 459-466.
12. Cowley, S., Paterson, H., Kemp, P., and Marshall, C.J. (1994). Activation of MAP kinase kinase is necessary and sufficient for PC12 Differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.
13. D'Arcangelo, G., and Halegoua, S. (1993). A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions. Mol. Cell. Biol. 13, 3146-3155.
14. Feng, G.-H., Hui, C.-C., and Pawson, T. (1993). SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinase. Science 259, 1607-1611.
15. Freeman, R.M., Plutzky, J., and Neel, B.G. (1992). Proc. Natl. Acad. Sci. USA 89, 11239-11244.
16. Fujioka, Y., Matozaki, T., Noguchi, T., Iwamatsu, A., Yamao, T., Takahashi, N., Tsuda, M., Takada, T., and Kasuga, M. (1996). A novel membrane glycoprotein, SHPS-1, that binds the SHP-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol. Cell. Biol. 16, 6887-6899.
17. Fukuda, M., Gotoh, Y., Tashibana, T., Gell, K., Hattori, S., Yoneda, Y., and Nishida, E. (1995). Induction of neurite outgrowth by MAP kinase in PC12 cells. Oncogene 11, 239-244.
18. Gomez, N., Tonks, N.K., Morrison, C., Harmar, T., and Cohen, P. (1990). Evidence for communication between nerve growth factor and protein tyrosine phosphorylation. FEBS Lett. 271, 119-122.
19. Greene, L.A., and Tischler, A.S. (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
20. Guan, K.L., and Dixon, J.E. (1991). Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate. J. Biol. Chem. 266, 17026-17030.
21. Hashimoto, Y., Matuoka, K., Takenawa, T., Muroya, K., Hattori, S., and Nakamura, S. (1994). Different interactions of Grb2/Ash molecule with the NGF and EGF receptors in rat pheochromocytoma PC12 cells. Oncogene 9, 869-875.
22. Herbst, R., Carroll, P.M., Allard, J.D., Schilling, J., Raabe, T., and Simon, M.A. (1996). Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. Cell 85, 899-909.
23. Jiao, H., Berrada, K., Yang, W., Tabrizi, M., Platanias, L.C., and Yi, T. (1996). Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol. Cell. Biol. 16, 6985-6992.
24. Kazlauskas, A., Feng, G.-S., Pawson, T., and Valus, M. (1993). The 63-kDa protein subunit that associates with the platelet derived growth factor receptor β subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. Proc. Natl. Acad. Sci. USA 90, 6939-6942.
25. Klingmuller, U., Lorenz, U., Cantley, L.C., Neel, B.G., and Lodish, H.F. (1995). Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 80, 729-738.
26. Kon-Kozlowski, M., Paru, G., Pawson, T., and Siminovitch, K.A. (1996). The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells. J. Biol. Chem. 271, 3856-3862.
27. Krautwald, S., Buscher, D., Kummer, V., Buder, S., and Baccarini, M. (1996). Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway. Mol. Cell. Biol. 16, 5955-5963.
28. Kremer, N.E., D'Arcangelo, G., Thomas, S.M., DeMarco, M., Brugge, J.S., and Halegoua, S. (1991). Siganl transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of Src and Ras action. J. Cell Biol. 115, 809-819.
29. Lechleider, R.J., Freeman, R.M.J., and Neel, B.G. (1993a). Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homolog, SH-PTP2. J. Biol. Chem. 268, 13434-13438.
30. Lechleider, R.J., Sugimoto, S., Bennett, A.M., Kashishian, A.S., Cooper, J.A., Shoelson, S.E., Walsh, C.T., and Neel, B.G. (1993b). Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor β. J. Biol. Chem. 268, 21478-21481.
31. Li, W., Nishimura, R., Kashishian, A., Batzer, A.G., Kim, W.J., H., Cooper, J.A., and Schlesinger, J. (1994). A new function for a phosphotyrosine phosphatase: linking Grb2-Sos to a receptor tyrosine kinase. Mol. Cell. Biol. 14, 509-517.
32. Marais, R., Light, Y., Paterson, H.F., and Marshall, C.J. (1995). Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J. 14, 3136-3145.
33. Matthews, R.J., Bowne, D.B., Flores, E., and Thomas, M.L. (1992). Characterization of hematopoietic intracellular protein tyrosine phosphatase: description of a phosphatase containing SH2 domain an other enriched in proline-, glutamic acid-, serine- and threoninerich sequences. Mol. Cell. Biol. 12, 2396-2405.
34. McGlade, J., Cheng, A., Pelicci, G., Pelicci, P.C., and Pawson, T. (1992). Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. Proc. Natl. Acad. Sci. USA 89, 8869-8873.
35. Meloche, S., Pages, G., and Pouysségur, J. (1992). Functional expression and growth factor activation of an epitope-tagged p44 mitogenactivated protein kinase, p44mapk. Mol. Biol. Cell 3, 63-71.
36. Milarski, K.L., and Saltiel, A.R. (1994). Expression of catalytical inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen activated protein kinase by insulin. J. Biol. Chem. 269, 21239-21243.
37. Neel, B.C. (1993). Structure and function of SH2-donaain containing tyrosine phosphatases. Semin. Cell Biol. 4, 419-432.
38. Noguchi, T., Matozaki, T., Horita, K., Fujioka, Y., and Kasuga, M. (1994). Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation. Mol. Cell. Biol. 14, 6674-6682.
39. Ouwens, D.M., Mikkers, H.M.M., van der Zon, G.C.M., Stein-Gerlach, M., Ullrich, A., and Maassen, J.A. (1996). Insulin-induced tyrosine dephosphorylation of paxillin and focal adhesion kinase requires active phosphotyrosine phosphatase ID. Biochem. J. 318, 609-614.
40. Pawson, T. (1994). SH2 and SH3 domains in signal transduction. Adv. Cancer Res. 64, 87-110.
41. Peng, Z.Y., and Cartwright, C.A. (1995). Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. Oncogene 11, 1955-1962.
42. Perkins, L.A., Larson, I., and Perrimon, N. (1992). corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 70, 225-236,
43. Plas, D.R., Johnson, R., Pingel, J.T., Matthews, R.J., Dalton, M., Roy, G., Chan, A.C., and Thomas, M.L. (1996). Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science 272, 1173-1176.
44. Plutzky, J., Neel, E.G., and Rosenberg, R.D. (1992). Isolation of a src homology z-containing tyrosine phosphatase. Proc. Natl. Acad. Sci. USA 89, 1123-1127.
45. Raabe, T., Riesgo Escovar, J., Liu, X., Bausenwein, B.S., Deak, P., Maroy, P., and Hafen, E. (1996). DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Rasl in Drosophila. Cell 85, 911-920.
46. Reeves, S.A., Sinha, B., Baur, I., Reinhold, D., and Harsh, G. (1995). An alternative role for the src-homology-domain-containing phosphotyrosine phosphatase (SH-PTP2) in regulating epidermal-growth-factor-dependent cell growth. Eur. J. Biochem. 233, 55-61.
47. Rivard, N., McKenzie, F.R., Brondello, J.M., and Pouysségur, J. (1995). The phosphotyrosine phosphatase PTP1D, but not PTP1C, is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G protein-coupled receptors. J. Biol. Chem. 270, 11017-11024.
48. Roche, S., McGlade, J., Jones, M., Gish, G.D., Pawson, T., and Courtneidge, S.A. (1996). Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways. EMBO 15, 4940-4948.
49. Sawada, T., Milarski, K.L., and Saltiel, A.R. (1995). Expression of a catalytically inert Syp blocks activation of MAP kinase pathway downstream of p21ras. Biochem. Biophys. Res. Commun. 234, 737-743.
50. Seger, R., Seger, D., Reszka, A.A., Munar, E.S., Eldar, F.H., Dobrowolska, G., Jensen, A.M., Campbell, J.S., Fischer, E.H., and Krebs, E.G. (1994). Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. J. Biol. Chem. 269, 25699-25709.
51. Shen, S.-H., Bastien, L., Posnaer, B.I., and Chrétien, P. (1991). A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases. Nature 352, 736-739.
52. Su, L., Zhao, Z., Bouchard, P., Banville, P., Fischer, E.H., Krebs, E.G., and Shen, S.-H. (1996). Positive effect of overexpressed protein-tyrosine phosphatase PTP1C on mitogen-activated signaling in 293 cells. J. Biol. Chem. 271, 10385-10390.
53. Tang, T.L., Freeman, R.M., Jr., O'Reilly, A.M., Neel, B.C., and Sokol, S.Y. (1995). The SH2-containing protein tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell 80, 473-483.
54. Tenev, T., Keilhack, H., Tomic, S., Stoyanov, B., Stein-Gerlach, M., Lammers, R., Krivtsov, A.V., Ullrich, A., and Bohmer, F.-D. (1997). Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera. J. Biol. Chem. 272, 5966-5973.
55. Tomic, S., Greiser, U., Lammers, R., Kharitonenkov, A., Imyanitov, E., Ullrich, A., and Bohmer, F.D. (1995). Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C. J. Biol. Chem. 270, 21277-21284.
56. Vaillancourt, R.R., Heasley, L.E., Zamarripa, J., Storey, B., Valius, M., Kazlauskas, A., and Johnson, G.L. (1995). Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation. Mol. Cell. Biol. 15, 3644-3653.
57. Vambutas, V., Kaplan, D.R., Sells, M.A., and Chernoff, J. (1995). Nerve growth factor stimulates tyrosine phosphorylation and activation of Src homology-containing protein-tyrosine phosphatase 1 in PC12 cells. J. Biol. Chem. 270, 25629-25633.
58. van der Geer, P., and Pawson, T. (1995). The PTB domain: a new protein module implicated in signal transduction. Trends Biochem. Sci. 20, 277-280.
59. Vogel, W., Lammers, R., Huang, J., and Ulrich, A. (1993). Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 259, 1611-1614.
60. Xiao, S., Rose, D.W., Sasaoka, T., Maegawa, H., J. Burke T.R., Roller, P.P., Shoelson, S.E., and Olefsky, J.M. (1994). Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J. Biol. Chem. 269, 21244-21248.
61. Yi, T., Cleveland, J.L., and Ihle, J.N. (1992). Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosoms. Mol. Cell. Biol. 12, 836-846.
62. Zhao, Z., Shen, S.-H., and Fischer, E.H. (1995a). Structure, regulation, and function of SH2 domain-containing protein tyrosine phosphatases. Adv. Prot. Phosphatases 9, 297-317.
63. Zhao, Z., Tan, Z., Wright, J.H., Diltz, C.D., Shen, S.-H., Krebs, E.G., and E.H. Fischer, (1995b). Altered expression of protein-tyrosine phosphatase 2C in 293 cells affects protein tyrosine phosphorylation and mitogen-activated protein kinase activation. J. Biol. Chem. 270, 11765-11769.