Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells

European Journal of Neuroscience

Volumn 10, Issue 6, 1998, Pages 1995-2008

  Ganju, Pam ^a   O'Bryan, John P ^b   Der, Channing ^b   Winter, Janet ^a   James, Iain F ^a  

^a Novatis Inst for Medical Sciences   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

K252a; MAPK; PD98059; PLC 1; TrkA; Tyrosine kinases

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CAPSAICIN; EPIDERMAL GROWTH FACTOR; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PHOSPHOLIPASE C; PROTEIN; PROTEIN TYROSINE KINASE; TYROSINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN; CONTROLLED STUDY; NERVE CELL CULTURE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELLS, CULTURED; GANGLIA, SPINAL; ISOENZYMES; NERVE GROWTH FACTORS; NEURONS, AFFERENT; PC12 CELLS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 0031842341     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1998.00209.x     Document Type: Article

References (4)

1. Aguayo, L.G. & White, G. (1992) Effects of nerve growth factor on TTX- and capsaicin-sensitivity in adult rat sensory neurons. Brain Res., 570, 61-67.
2. Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T. & Saltiel, A.R. (1995) PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem, 270, 27489-27494.
3. Aloe, L., Tuveri, M.A., Carcassi, U. & Levi-Montalcini, R. (1992) Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis Rheum., 35, 351-355.
4. Barker, P.A., Lomen-Hoerth, C., Gensch, E.M., Meakin, S.O., Glass, D.J. & Shooter, E.M. (1993) Tissue-specific alternative splicing generates two isoforms of the TrkA receptor, J. Biol. Chem., 268, 15150-15157.