Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: A different environment but similar recognition of an extended glutamate conformation

Journal of Medicinal Chemistry

Volumn 42, Issue 9, 1999, Pages 1546-1555

  Jullian, Nathalie ^a   Brabet, Isabelle ^b   Pin, Jean Philippe ^b   Acher, Francine C ^c  

^a Parc Club Orsay Universite   (France)

^b INSERM   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EGLUMETAD; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; IBOTENIC ACID; QUISQUALIC ACID; RECEPTOR SUBTYPE;

ARTICLE; BRAIN DISEASE; DRUG CONFORMATION; DRUG DESIGN; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HUMAN; HUMAN CELL; MENTAL DISEASE; MOLECULAR MODEL; NEUROTRANSMITTER RELEASE; PHARMACOPHORE; SYNAPSE;

ANIMALS; BINDING SITES; CELL LINE; CHO CELLS; CRICETINAE; GLUTAMATES; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, METABOTROPIC GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033529055     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980571q     Document Type: Article

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