메뉴 건너뛰기




Volumn 74, Issue 1, 1996, Pages 13-20

Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro

Author keywords

in vitro; metabotropic glutamate receptor; spinal cord; ventral root potential

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; CAPSAICIN; CONCANAVALIN A; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0029742723     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00101-7     Document Type: Article
Times cited : (52)

References (41)
  • 1
    • 0028149789 scopus 로고
    • Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
    • Aiba A., Kano M., Chen C., Stanton M. E., Fox G. D., Herrup K., Zwingman T. A. and Tonegawa S. (1994) Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell 79, 377-388.
    • (1994) Cell , vol.79 , pp. 377-388
    • Aiba, A.1    Kano, M.2    Chen, C.3    Stanton, M.E.4    Fox, G.D.5    Herrup, K.6    Zwingman, T.A.7    Tonegawa, S.8
  • 4
    • 0027080086 scopus 로고
    • Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn
    • Bleakman D., Rusin K. I., Chard P. S., Glaum S. R. and Miller R. J. (1992) Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn. Molec. Pharmac. 42, 192-196.
    • (1992) Molec. Pharmac. , vol.42 , pp. 192-196
    • Bleakman, D.1    Rusin, K.I.2    Chard, P.S.3    Glaum, S.R.4    Miller, R.J.5
  • 5
    • 0026732924 scopus 로고
    • Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid
    • Cerne R. and Randic M. (1992) Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid. Neurosci. Lett. 144, 180-184.
    • (1992) Neurosci. Lett. , vol.144 , pp. 180-184
    • Cerne, R.1    Randic, M.2
  • 6
    • 0019723082 scopus 로고
    • 2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation
    • Davies J., Francis A. A., Jones A. W. and Watkins J. C. (1981) 2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation. Neurosci. Lett. 21, 77-81.
    • (1981) Neurosci. Lett. , vol.21 , pp. 77-81
    • Davies, J.1    Francis, A.A.2    Jones, A.W.3    Watkins, J.C.4
  • 7
    • 0023605956 scopus 로고
    • Evidence for involvement of N-methylaspartate receptors in "windup" of class 2 neurones in the dorsal horn of the rat
    • Davies S. N. and Lodge D. (1987) Evidence for involvement of N-methylaspartate receptors in "windup" of class 2 neurones in the dorsal horn of the rat. Brain Res. 424, 402-406.
    • (1987) Brain Res. , vol.424 , pp. 402-406
    • Davies, S.N.1    Lodge, D.2
  • 8
    • 0026478798 scopus 로고
    • Desensitisation of bradykinin-induced activation of peripheral nociceptors
    • (eds Bonner G., Fritz H., Unger Th., Roscher A., Luppertz K.) Birkauser, Basel
    • Dray A., Patel I. A., Perkins M. N., Rueff A. and Urban L. (1992) Desensitisation of bradykinin-induced activation of peripheral nociceptors. In Recent Progress on Kinins, (eds Bonner G., Fritz H., Unger Th., Roscher A., Luppertz K.) pp. 93-98. Birkauser, Basel.
    • (1992) Recent Progress on Kinins , pp. 93-98
    • Dray, A.1    Patel, I.A.2    Perkins, M.N.3    Rueff, A.4    Urban, L.5
  • 10
    • 0028362318 scopus 로고
    • Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism
    • Gereau R. W. and Conn P. J. (1994) Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism. Neuron 12, 1121-1129.
    • (1994) Neuron , vol.12 , pp. 1121-1129
    • Gereau, R.W.1    Conn, P.J.2
  • 11
    • 0028350739 scopus 로고
    • Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes
    • Hayashi Y., Sekiyama N., Nakanishi S., Jane D. E., Sunter D. C., Birse E. F., Udvarhelyi P. M. and Watkins J. C. (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J. Neurosci. 14, 3370-3377.
    • (1994) J. Neurosci. , vol.14 , pp. 3370-3377
    • Hayashi, Y.1    Sekiyama, N.2    Nakanishi, S.3    Jane, D.E.4    Sunter, D.C.5    Birse, E.F.6    Udvarhelyi, P.M.7    Watkins, J.C.8
  • 12
    • 0027209890 scopus 로고
    • A novel metabotropic glutamate receptor agonist: Marked depression of monosynaptic excitation in the newborn rat isolated spinal cord
    • Ishida M., Saitoh T., Shimanoto Y. and Shinozaki H. (1993) A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord. Br. J. Pharmac. 109, 1169-1177.
    • (1993) Br. J. Pharmac. , vol.109 , pp. 1169-1177
    • Ishida, M.1    Saitoh, T.2    Shimanoto, Y.3    Shinozaki, H.4
  • 13
    • 0027174866 scopus 로고
    • Stereospecific antagonism by (+)-α-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones
    • Jane D. E., Jones P. L. St. J., Pook P. C.-K., Salt T. E., Sunter D. C. and Watkins J. C. (1993) Stereospecific antagonism by (+)-α-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones. Neuropharmacology 32, 725-727.
    • (1993) Neuropharmacology , vol.32 , pp. 725-727
    • Jane, D.E.1    Jones, P.L.St.J.2    Pook, P.C.-K.3    Salt, T.E.4    Sunter, D.C.5    Watkins, J.C.6
  • 14
    • 0029131044 scopus 로고
    • Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vitro
    • Jones M. W. and Headley P. M. (1995) Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vitro. Neuropharmacology 34, 1025-1031.
    • (1995) Neuropharmacology , vol.34 , pp. 1025-1031
    • Jones, M.W.1    Headley, P.M.2
  • 15
    • 0027738679 scopus 로고
    • Excitatory amino-acid receptor mediated neurotransmission from cutaneous afferents in the rat dorsal horn in vitro
    • King A. E. and Lopez-Garcia J. A. (1993) Excitatory amino-acid receptor mediated neurotransmission from cutaneous afferents in the rat dorsal horn in vitro. J. Physiol., Lond. 472, 443-457.
    • (1993) J. Physiol., Lond. , vol.472 , pp. 443-457
    • King, A.E.1    Lopez-Garcia, J.A.2
  • 16
    • 0028310856 scopus 로고
    • Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurones and potentiates excitatory synaptic transmission
    • McBain C. J., Dichiara T. J. and Kauer J. A. (1994) Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurones and potentiates excitatory synaptic transmission. J. Neurosci. 14, 4433-4445.
    • (1994) J. Neurosci. , vol.14 , pp. 4433-4445
    • McBain, C.J.1    Dichiara, T.J.2    Kauer, J.A.3
  • 17
    • 0027193908 scopus 로고
    • Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors
    • Meller S. T., Dykstra C. and Gebhart G. F. (1993) Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors. NeuroReport 4, 879-882.
    • (1993) NeuroReport , vol.4 , pp. 879-882
    • Meller, S.T.1    Dykstra, C.2    Gebhart, G.F.3
  • 18
    • 0001895691 scopus 로고
    • Response of single dorsal cord cells to peripheral cutaneous unmyelinated fibres
    • Mendell L. M. and Wall P. D. (1965) Response of single dorsal cord cells to peripheral cutaneous unmyelinated fibres. Nature, Lond. 206, 97-99.
    • (1965) Nature, Lond. , vol.206 , pp. 97-99
    • Mendell, L.M.1    Wall, P.D.2
  • 19
    • 0027472096 scopus 로고
    • The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro
    • Nagy I., Maggi C. A., Dray A., Woolf C. J. and Urban L. (1993) The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro. Neuroscience 52, 1029-1037.
    • (1993) Neuroscience , vol.52 , pp. 1029-1037
    • Nagy, I.1    Maggi, C.A.2    Dray, A.3    Woolf, C.J.4    Urban, L.5
  • 20
    • 0028242970 scopus 로고
    • Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons
    • Neugebauer V., Lucke T. and Schaible H.-G. (1994) Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons. Eur. J. Neurosci. 6, 1179-1186.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1179-1186
    • Neugebauer, V.1    Lucke, T.2    Schaible, H.-G.3
  • 21
    • 0027937531 scopus 로고
    • Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization
    • Nusser Z., Mulvihill E., Streit P. and Somogyi P. (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience 61, 421-427.
    • (1994) Neuroscience , vol.61 , pp. 421-427
    • Nusser, Z.1    Mulvihill, E.2    Streit, P.3    Somogyi, P.4
  • 22
    • 0027168754 scopus 로고
    • Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study
    • Ohishi H., Shigemoto R., Nakanishi S. and Mizuno N. (1993) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study. J. comp. Neurol. 335, 252-266.
    • (1993) J. Comp. Neurol. , vol.335 , pp. 252-266
    • Ohishi, H.1    Shigemoto, R.2    Nakanishi, S.3    Mizuno, N.4
  • 23
    • 0027190384 scopus 로고
    • Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat
    • Ohishi H., Shigemoto R., Nakanishi S. and Mizuno N. (1993) Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience 53, 1009-1018.
    • (1993) Neuroscience , vol.53 , pp. 1009-1018
    • Ohishi, H.1    Shigemoto, R.2    Nakanishi, S.3    Mizuno, N.4
  • 24
    • 0028231354 scopus 로고
    • The effect of trans-ACPD, a metabotropic excitatory amino acid receptor agonist, on the responses of primate spinothalamic tract neurons
    • Palacek J., Paleckova V., Dougherty P. M. and Willis W. D. (1994) The effect of trans-ACPD, a metabotropic excitatory amino acid receptor agonist, on the responses of primate spinothalamic tract neurons. Pain 56, 261-269.
    • (1994) Pain , vol.56 , pp. 261-269
    • Palacek, J.1    Paleckova, V.2    Dougherty, P.M.3    Willis, W.D.4
  • 25
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin J.-P. and Duvoisin R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34, 1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.-P.1    Duvoisin, R.2
  • 26
    • 0029012608 scopus 로고
    • Get receptive to metabotropic glutamate receptors
    • Pin J.-P. and Bockaert J. (1995) Get receptive to metabotropic glutamate receptors. Curr. Opin. Neurobiol. 5, 342-349.
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 342-349
    • Pin, J.-P.1    Bockaert, J.2
  • 27
    • 0041989904 scopus 로고
    • Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors
    • Schoepp D., Bockaert J. and Sladeczek F. (1991) Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmac. Sci. Special Report 74-81.
    • (1991) Trends Pharmac. Sci. Special Report , pp. 74-81
    • Schoepp, D.1    Bockaert, J.2    Sladeczek, F.3
  • 28
    • 0026716350 scopus 로고
    • Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ study in adult and developing rat
    • Shigemoto R., Nakanishi S. and Mizuno N. (1992) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ study in adult and developing rat. J. comp. Neurol. 322, 122-135.
    • (1992) J. Comp. Neurol. , vol.322 , pp. 122-135
    • Shigemoto, R.1    Nakanishi, S.2    Mizuno, N.3
  • 29
    • 0027216127 scopus 로고
    • Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-calibre afferents is a predictor of action potential windup in rat spinal neurons in vitro
    • Sivilotti L. G., Thompson S. W. N. and Woolf C. J. (1993) Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-calibre afferents is a predictor of action potential windup in rat spinal neurons in vitro. J. Neurophysiol. 69(5), 1-11.
    • (1993) J. Neurophysiol. , vol.69 , Issue.5 , pp. 1-11
    • Sivilotti, L.G.1    Thompson, S.W.N.2    Woolf, C.J.3
  • 30
    • 0025354044 scopus 로고
    • Activity-dependent changes in rat ventral horn neurons in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a D-2-amino-5-phosphonovaleric acid sensitive windup
    • Thompson S. W. N., King A. E. and Woolf C. J. (1990) Activity-dependent changes in rat ventral horn neurons in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a D-2-amino-5-phosphonovaleric acid sensitive windup. Eur. J. Neurosci. 2, 638-639.
    • (1990) Eur. J. Neurosci. , vol.2 , pp. 638-639
    • Thompson, S.W.N.1    King, A.E.2    Woolf, C.J.3
  • 31
    • 0026459946 scopus 로고
    • Long duration ventral root potentials in the neonatal rat spinal cord in vitro; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists
    • Thompson S. W. N., Gerber G., Sivilotti L. G. and Woolf C. J. (1992) Long duration ventral root potentials in the neonatal rat spinal cord in vitro; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists. Brain Res. 595, 87-97.
    • (1992) Brain Res. , vol.595 , pp. 87-97
    • Thompson, S.W.N.1    Gerber, G.2    Sivilotti, L.G.3    Woolf, C.J.4
  • 32
    • 0027340673 scopus 로고
    • 2 receptor activation to high threshold afferent fibre evoked ventral root responses in the rat spinal cord in vitro
    • 2 receptor activation to high threshold afferent fibre evoked ventral root responses in the rat spinal cord in vitro. Brain Res. 625, 100-108.
    • (1993) Brain Res. , vol.625 , pp. 100-108
    • Thompson, S.W.N.1    Urban, L.2    Dray, A.3
  • 33
    • 0028301271 scopus 로고
    • Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- And C-fibre mediated responses in the rat spinal cord in vitro
    • Thompson S. W. N., Dray A. and Urban L. (1994) Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fibre mediated responses in the rat spinal cord in vitro. J. Neurosci. 14, 3672-3687.
    • (1994) J. Neurosci. , vol.14 , pp. 3672-3687
    • Thompson, S.W.N.1    Dray, A.2    Urban, L.3
  • 34
    • 0028948248 scopus 로고
    • No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro
    • Thompson S. W. N., Levers T., Babbedge R., Dray A. and Urban L. (1995) No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro. Neurosci. Lett. 188, 121-124.
    • (1995) Neurosci. Lett. , vol.188 , pp. 121-124
    • Thompson, S.W.N.1    Levers, T.2    Babbedge, R.3    Dray, A.4    Urban, L.5
  • 35
    • 0026589605 scopus 로고
    • Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro
    • Urban L. and Dray A. (1992) Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro. Neuroscience 47, 693-702.
    • (1992) Neuroscience , vol.47 , pp. 693-702
    • Urban, L.1    Dray, A.2
  • 36
    • 0028329059 scopus 로고
    • Tachykinin induced regulation of excitatory amino acid responses in the rat spinal cord in vitro
    • Urban L., Naeem S., Patel A. I. and Dray A. (1994) Tachykinin induced regulation of excitatory amino acid responses in the rat spinal cord in vitro. Neurosci Lett. 168, 185-188.
    • (1994) Neurosci Lett. , vol.168 , pp. 185-188
    • Urban, L.1    Naeem, S.2    Patel, A.I.3    Dray, A.4
  • 37
    • 0027933184 scopus 로고
    • Modulation of spinal excitability: Co-operativity between neurokinins and excitatory amino acid neurotransmitters
    • Urban L., Thompson S. W. N. and Dray A. (1994) Modulation of spinal excitability: co-operativity between neurokinins and excitatory amino acid neurotransmitters. Trends Neurosci. 17, 432-438.
    • (1994) Trends Neurosci. , vol.17 , pp. 432-438
    • Urban, L.1    Thompson, S.W.N.2    Dray, A.3
  • 38
    • 0028586837 scopus 로고
    • Cellular and subcellular localisation of the mGluR5a metabotropic glutamate in the rat spinal cord
    • Vidnyanszky Z., Hamori J., Negyessy L., Rueegg D., Knoepfel T., Kuhn R. and Goercs T. J. (1994) Cellular and subcellular localisation of the mGluR5a metabotropic glutamate in the rat spinal cord. NeuroReport 6, 209-213.
    • (1994) NeuroReport , vol.6 , pp. 209-213
    • Vidnyanszky, Z.1    Hamori, J.2    Negyessy, L.3    Rueegg, D.4    Knoepfel, T.5    Kuhn, R.6    Goercs, T.J.7
  • 39
    • 0027992583 scopus 로고
    • Phenylglycine derivatives as antagonists of metabotropic glutamate receptors
    • Watkins J. C. and Collingridge G. L. (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends pharmac. Sci. 15, 333-342.
    • (1994) Trends Pharmac. Sci. , vol.15 , pp. 333-342
    • Watkins, J.C.1    Collingridge, G.L.2
  • 40
    • 0023266753 scopus 로고
    • Physiology and morphology of multireceptive neurons with C-fibre afferent inputs in the deep dorsal horn of the rat lumber spinal cord
    • Woolf C. J. and King A. E. (1987) Physiology and morphology of multireceptive neurons with C-fibre afferent inputs in the deep dorsal horn of the rat lumber spinal cord. J. Neurophysiol. 58, 460-479.
    • (1987) J. Neurophysiol. , vol.58 , pp. 460-479
    • Woolf, C.J.1    King, A.E.2
  • 41
    • 0028350254 scopus 로고
    • Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons
    • Young M. R., Fleetwood-Walker S. M., Mitchell R. and Munro F. E. (1994) Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons. Neuropharmacology 33, 141-144.
    • (1994) Neuropharmacology , vol.33 , pp. 141-144
    • Young, M.R.1    Fleetwood-Walker, S.M.2    Mitchell, R.3    Munro, F.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.