L'activation du N F-K B au cours des infections bactériennes : Une réaction primordiale de défense de l'hôte

Medecine Therapeutique

Volumn 5, Issue 10, 1999, Pages 797-806

  Kayal, Samer ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; TUMOR NECROSIS FACTOR;

BACTERIAL INFECTION; BACTERIAL VIRULENCE; IMMUNE RESPONSE; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033391821     PISSN: 12646520     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. Medzhitov R., Janevvay CA., Jr. 1997. Innate immunity : the virtues of a nonclonal system of recognition. Cell 91 :295-298.
2. May M.J., Ghosh S. 1998. Signal transduction through NF-kappa B. Immunol Today 19: 80-88.
3. Israel A. 1997. Signal transduction. IkappaBkinase all zipped up. Nature388 :519-521.
4. Sen R., Baltimore D. 1986. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell46 :705-716.
5. Cay N.J., Keith F.J. 1991. Drosophila Toll andlU receptor. Nature351 :355-356.
6. Beg A.A., Sha W.C., Bronson R.T., Baltimore D. 1995. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes Dev9 :2736-2746.
7. Thompson J.E., Phillips R.J., ErdjumentBromage H., Tempst P., Ghosh S. 1995.1 kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B. Cell80:573-582.
8. Weil R., Laurent-Winter C, Israel A. 1997. Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha.JBio!Chem272 :9942-9949.
9. Suyang H., Phillips R., Douglas I., Ghosh S. 1996. Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B. Mol Cell Biol 16:5444-5449.
10. Hu Y., et al. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science284:316-320.
11. Li Q., Van Antwerp D., Mercurio F., Lee K.F., Verma I.M. 1999. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. 5dence284 :321-325. 12. Lee F.S., Hagler J., Chen Z.J., Maniatis T. 1997. Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell88 :213-222.
12. Nakano H., etal. 1998. Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA 95:3537-3542.
13. Perona R., Montaner S., Saniger L., Sanchez-Perez I., Bravo R., Laçai JC. 1997. Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes Devl 1 : 463-475.
14. Yamaoka S., etal. 1998. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NFkappaB activation. Cell 93 :1231-1240.
15. Cohen L., Henzel W.J., Baeuerle P.A. 1998. IKAP is a scaffold protein of the IkappaB kinase complex. Nature395 :292-296. 17. Dinarello C.A. 1996. Biologic basis for interleukin-1 in disease. Blood87 : 20952147.
16. Medzhitov R., et al. 1998. MyD88 is an adaptor protein in the h Toll/Ill receptor family signaling pathways. Mol Cell 2 :253-258.
17. Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., Hoffmann J.A. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973-983.
18. Medzhitov R., Preston-Hurlburt P., Janeway C.A., Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nafure388 :394397.
19. Burns K., eraJ. 1998. MyD88, an adapter protein involved in interleukin-1 signaling. 1 BiolChem 273 :12203-12209.
20. Muzio M., Ni}., Feng P., Dixit V.M. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL 1 signaling. Science278 :1612-1615.
21. Cao Z., Xiong J., Takeuchi M., Kurama T., Coeddel D.V. 1996. TRAF6 is a signal transducer for interleukin-1. Na(ure383 :443-446.
22. Ninomiya-Tsuji J., Kishimoto K., Hiyama A., Inoue J., Cao Z., Matsumoto K. 1999. The kinase TAK1 can activate the NIKI kappaB as well as the MAP kinase cascade in the IL1 signalling pathway. Na(ure398 : 252-256.
23. Hsu H., Shu H.B., Pan M.C., Coeddel D.V. 1996.TRADD-TRAF2 andTRADDFADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84 :299-308.
24. Hsu H., Huang J., Shu H.B., Baichvval V., Coeddel D.V. 1996. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity4 : 387-396.
25. Nagata S. 1997. Apoptosis by death factor. Cell 88 :355-365.
26. Beg A.A., Baltimore D. 1996. An essential role for NF-kappaB in preventing TNF-alphainduced cell death. Science274 :782-784.
27. Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S., Jr. 1998. NFkappaB antiapoptosis : induction of TRAF1 and TRAF2 and C-IAP1 and c- IAP2 to suppress caspase-8 activation. 5c/ence281 : 1680-1683.
28. Wu M.X., Ao Z., Prasad K.V., Wu R., Schlossman S.F. 1998. IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science281 : 998-1001.
29. Clifton D.R., et al. 1998. NF-kappa Bdependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection. Proc Natl AcadSci USA 95 : 4646-4651.
30. Henderson B., Poole S., Wilson M. 1996. Bacterial modulins : a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol Rev 60:316-341.
31. Poltorak A., et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/1 OScCr mice : mutations in Tlr4 gene. Science282 : 2085-2088.
32. Yang R.B., etal. 1998. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature395 :284-288.
33. Gupta D., Kirkland T.N., Viriyakosol S., Dziarski R. 1996. CD14 is a cell-activating receptor for bacterial peptidoglycan. J Biol Chem27\ :23310-23316.
34. Palombella V.J., etal. 1998. Role of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritis. ProcNatl AcadSciUSABB : 15671-15676.
35. Schwandner R., Dziarski R., Wesche H., Rothe M., Kirschning C.J. 1999. Peptidoglycan- and lipoteichoic acid-induced ceil activation is mediated by Toll-like receptor 2. J Biol Chem274 :17406-17409.
36. Yoshimura A., Lien E., Ingalls R.R., Tuomanen E., Dziarski R., Golenbock D. 1999. Cutting edge : recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. y Immunol 163 :1 -5.
37. Wooten R.M., Modur V.R., MclntyreT.M., Weis J.J. 1996. Borrella burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells. J Immunol 157:4584-4590.
38. Ebnet K., Brown K.D., Siebenlist U.K., Simon M.M., Shaw S. 1997. Borrella burgdorferi activates nuclear factor-kappa B and is a potent inducerof chemokine and adhesion molecule gene expression in endothelial cells and fibroblasts./Immunol 158 :3285-3292.
39. 41.Theus S.A., Harrich D.A., Gaynor R., Radolf J.D., Norgard M.V. 1998. Treponema pallidum, lipoproteins, and synthetic lipoprotein analogues induce human immunodeficiency virus type 1 gene expression in monocytes via NF-kappaB activation. J Infect Dis 177:941 -950.
40. Brightbill H.D., etal. 1999. Host defense mechanisms triggered by microbial lipoproteins through Toll-like receptors. Science 285 :732-736.
41. 43.AliprantisA.O., etal. 1999. Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll- like Receptor-2. Science 285 :736-739.
42. Brown M.C., Taffet S.M. 1995. Lipoarabinomannans derived from different strains of Mycobacterium tuberculosis differentially stimulate the activation of NF-kappa B and KBF1 in murine macrophages. Infect Immun 63 :1960-1968.
43. Giri O.K., Mehta R.T., Kansal R.G., Aggarwal B.B. 1998. Mycobacterium aviumintracellulare complex activates nuclear transcription factor-kappaB in different cell types through reactive oxygen intermediates. J Immunol 161 :4834-4841.
44. Roach T.I., Chatterjee D., Blackwell J.M. 1994. Induction of early-response genes KC and JE by mycobacterial lipoarabinomannans : regulation of KC expression in murine macrophages by Lsh/lty/Bcg (candidate Nramp). Infect Immun 62 :1176-1184.
45. Feng S.H., Lo S.C. 1999. Lipid extract of Mycoplasma penetrans proteinase K-digested lipid- associated membrane proteins rapidly activates NF-kappaB and activator protein 1. Infect Immun 67 :2951-2956.
46. Bernier R., Barbeau B., Tremblay M.J., Olivier M. 1998. The lipophosphoglycan of Lcishmania cfonovan/up-regulates HIV-1 transcription in T cells through the nuclear factor-kappaB elements. J Immunol 160 : 2881-2888.
47. DiMango E., Ratner A.J., Bryan R., Tabibi S., Prince A. 1998. Activation of NFkappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J Clin Invest 101 :2598-2605.
48. Naumann M., Wessier S., Bartsch C, Wieland B., Meyer T.F. 1997. Neisseria gonorrhoeaeepithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines. J ExpMed 186:247-258.
49. Galan J.E., Collmer A. 1999. Type III secretion machines : bacterial devices for protein delivery into host cells. Science284 : 1322-1328.
50. Rosenshine I., Ruschkowski S., Stein M., Reinscheid D.J., Mills S.D., Finlay B.B. 1996. A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation. Embo] 15:2613-2624.
51. Eaves-Pyles T., Szabo C., Salzman A.L 1999. Bacterial invasion is not required for activation of NF-kappaB in enterocytes. Infect Immun 67 :800-804.
52. Hardt W.D., Chen L.M., Schuebel K.E., Bustelo X.R., Galan J.E. 1998. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells. Cell 93 : 815-826.
53. Adam T., Giry M., Boquet P., Sansonetti P. 1996. Rho-dependent membrane folding causes Shigella entry into epithelial cells. Embo J15 :3315-3321.
54. Dyer R.B., Collaco C.R., Nicsel D.W., Herzog N.K. 1993. Shigella flexneriinvasion of HeLa cells induces NF-kappa B DNA-binding activity. Infect Immune] : 4427-4433.
55. Zychlinsky A., Fitting C, Cavaillon J.M., Sansonetti P.J. 1994. Interlcukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. J Clin Invest 94:1328-1332.
56. Simonet M., Richard S., Berche P. 1990. Electron microscopic evidence for in vivo extracellular localization of Yersiniapseudotuberculosis harboring the pYV plasmid. Infect Immun 58 : 841-845.
57. Cornells G.R., Wolf-Watz H. 1997. The Yersinia Yop virulon : a bacterial system for subverting eukaryotic cells. MolMicrobiol 23:861-867.
58. Fallman M., Persson C, Wolf-Watz H. 1997. Yersinia proteins that target host eel I signaling pathways. J Clin Invest 99 :1153-1157.
59. Ruckdeschel K., et al. 1998. Yersinia enterocolitica impairs activation of transcription factor NF-kappaB : involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor alpha production. J Exp Med 187:1069-1079.
60. Schesser K., Spuk A.K., Dukuzumuremyi J.M., Neurath M.F., Pettersson S., WolfWatz H. 1998. The yopj locus is required for Versm/a-mediated inhibition of NF-kappaB activation and cytokine expression : Yopj contains a eukaryotic SH2-like domain that is essential for its repressive activity. Mol Microbiol 28:1067-1079.
61. Burns D.L. 1999. Biochemistry of type IV secretion. CurrOpin Microbiol2 :25-29.
62. Covacci A., Telford J.L., Del Giudice C., Parsonnet J., Rappuoli R. 1999. HelicobacterpyloriVirulence and genetic geography. 5c/ence284:1328-1333.
63. Aihara M., et al. 1997. Mechanisms involved in Helicobacterpy/or/'-induced interleukin-8 production by a gastric cancer cell line, MKN45. Infect Immun 65 :32183224.
64. Glocker E., Lange C., Covacci A., Bereswill S., Kist M., Pahl H.L. 1998. Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation. Infect Immun 66 :2346-2348.
65. Munzenmaier A., et al. 1997. A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factorkappa B. ; Immunol 159 : 6140-6147.
66. Foo S.Y., Nolan G.P. 1999. NF-kappaB to the rescue : RELs, apoptosis and cellular transformation. Trends Genet 15 :229-235.
67. Kayal S., Lilienbaum A., Poyart C., Memet S., Israel A., Berche P. 1999. Listeriolysin O-dependent activation of endothelial cells during infection with Listcria monocytogenes : activation of NF-kappa B and upregulation of adhesion molecules and chemokines. Mol Microblol31 :1709-1722.
68. Drevets D.A. 1997. Listeria monocytogenes infection of cultured endothelial cells stimulates neutrophil adhesion and adhesion molecule expression. J Immunol 158 :53055313.
69. Sakiri R., Ramegovvda B., Tesh V.L. 1998. Shiga toxin type 1 activates tumor necrosis factor-alpha gene transcription and nuclear translocation of thetranscriptional activators nuclear factor-kappaB and activator proteinl./ooc/92 :558-566.
70. Krüll M., et al. 1999. Signal Transduction Pathways Activated in Endothelial Cells Following Infection with Chlamydiapneumoniae. ) Immunol 162 :4834-4841.
71. Sporn L.A., et al. 1997. Rickettsia rickettsii infection of cultured human endothelial cells induces NF-kappaB activation. Infect Immun 65 :2 786-2 791.
72. Sahni S.K., Van Antwerp D.J., Eremeeva M.E., Silverman D.J., Marder V.J., Sporn L.A. 1998. Proteasome-independent activation of nuclear factor kappaB in cytoplasmic extracts from human endothelial cells by Rickettsia rickettsii. Infect Immun 66:1827-1833.
73. Portnoy D.A., Chakraborty T., Goebel W., Cossart P. 1992. Molecular determinants of Listeria monocytogenes pathogenesis. Infect Immun 60 :1263-1267.
74. Häuf N., Goebel W., Fiedler F., Sokolovic Z., Kühn M. 1997. Listeria monocytogenes infection of P388D1 macrophages results in a biphasic NF-kappaB (RelA/p50) activation induced by lipoteichoic acid and bacterial phospholipases and mediated by IkappaBalpha and IkappaBbeta degradation. Proc Natl AcadSci USA 94 :9394-9399.