Yersinia proteins that target host cell signaling pathways

Journal of Clinical Investigation

Volumn 99, Issue 6, 1997, Pages 1153-1157

  Fällman, Maria ^a   Persson, Cathrine ^a   Wolf Watz, Hans ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE; OUTER MEMBRANE PROTEIN;

BACTERIAL TRANSLOCATION; BACTERIAL VIRULENCE; HELA CELL; HOST PARASITE INTERACTION; HUMAN; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; YERSINIA;

EID: 0242504622     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119270     Document Type: Review

References (35)

1. Forsberg, Å., R. Rosqvist, and H. Wolf-Watz. 1994. Regulation and polarized transfer of the Yersinia outer proteins (Yops) involved in antiphagocytosis. Trends Microbiol. 2:14-19.
2. Van Gijsegem, F., S. Genin, and C. Bocher. 1993. Conservation of secretion pathways for pathogenicity determinants of plant and animal bacteria. Trends Microbiol. 1:175-180.
3. Rosqvist, R., S. Håkansson, Å. Forsberg, and H. Wolf-Watz. 1995. Functional conservation of the secretion and translation machinery for virulence proteins of yersiniae, salmonellae, and shigellae. EMBO (Eur. Mol. Biol. Organ.) J. 14:4187-4195.
4. Hermant, D., R. Menard, N. Arricau, C. Parsot, and M.Y. Popoff. 1995. Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells. Mol. Microbiol. 17:781-789.
5. Rosqvist, R., K.-E. Magnusson, and H. Wolf-Watz. 1994. Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. EMBO (Eur. Mol. Biol. Organ.) J. 13:964-972.
6. Sory, M.-P., and G.R. Cornelis. 1994. Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cells. Mol. Microbiol. 14:583-594.
7. Persson, C., R. Nordfelth, A. Holmström, S. Håkansson, R. Rosqvist, and H. Wolf-Watz. 1995. Cell-surface-bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell. Mol. Microbiol. 18:135-150.
8. Pettersson, J., R. Nordfelth, E. Dubinina, T. Bergman, M. Gustafsson, K.-E. Magnusson, and H. Wolf-Watz. 1996. Modulation of virulence factor expression by pathogen target cell contact. Science (Wash. DC). 273:1231-1233.
9. Håkansson, S.E., K. Schesser, C. Persson, E.E. Galyov, R. Rosqvist, F. Homblé, and H. Wolf-Watz. 1996. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity. EMBO (Eur. Mol. Biol. Organ.) J. 15:5812-5823.
10. Håkansson, S., T. Bergman, J.-C. Vanooteghem, G. Cornelis, and H. Wolf-Watz. 1993. YopB and YopD constitute a novel class of Yersinia Yop proteins. Infect. Immun. 61:71-80.
11. Galyov, E., S. Håkansson, Å. Forsberg, and H. Wolf-Watz. 1993. A secreted protein kinase of Yersinia pseudotuberculosis is an indispensable virulence determinant. Nature (Lond.). 361:730-732.
12. Håkansson, S., E.E. Galyov, R. Rosqvist, and H. Wolf-Watz. 1996. The Yersinia YpkA Ser/Thr kinase is translocated and subsequently targeted to the inner surface of the HeLa cell plasma membrane. Mol. Microbiol. 20:593-603.
13. Fällman, M., K. Andersson, S. Håkansson, K.-E. Magnusson, O. Stendahl, and H. Wolf-Watz. 1995. Yersinia pseudotuberculosis inhibits Fc receptor-mediated phagocytosis in J774 cells. Infect. Immun. 63:3117-3124.
14. Ruckdeschel, K., A. Roggenkamp, S. Schubert, and J. Heesemann. 1996. Differential contribution of Yersinia enterocolitica virulence factors to evasion of microbicidal action of neutrophils. Infect. Immun. 64:724-733.
15. Rosqvist, R., Å. Forsberg, and H. Wolf-Watz. 1991. Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption. Infect. Immun. 59:4562-4569.
16. Kulich, S.M., T.L. Yahr, L.M. Mende-Mueller, J.T. Barbieri, and D.W. Frank. 1994. Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388. J. Biol. Chem. 269:10431-10437.
17. Coburn, J., R.T. Wyatt, B.H. Iglewski, and M. Gill. 1989. Several GTP-binding proteins, including p21c-H-ras are preferred substrates of Pseudomonas aeruginosa exoenzyme S. J. Biol. Chem. 264:9004-9008.
18. Guan, K., and J.E. Dixon. 1990. Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia. Science (Wash. DC). 249:553-556.
19. Zhang, Z.-Y., J.C. Clemens, H.L. Schubert, J.A. Stuckey, M.W.F. Fischer, D.M. Hume, M.A. Saper, and J.E. Dixon. 1992. Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. J. Biol. Chem. 267:23759-23766.
20. Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions. EMBO (Eur. Mol. Biol. Organ.) J. In press.
21. Rosenshine, I., V. Duronio, and B.B. Finlay. 1992. Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells. Infect. Immun. 60:2211-2217.
22. Isberg, R.R., and G. Tran van Nhieu. 1994. Binding and internalization of microorganisms by integrin receptors. Trends Microbiol. 2:10-14.
23. Andersson, K., N. Carballeira, K.-E. Magnusson, C. Persson, O. Stendahl, H. Wolf-Watz, and M. Fällman. 1996. YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signaling associated with phagocytosis. Mol. Microbiol. 20:1057-1069.
24. Cas, a Src homology 3-containing molecule having multiple Scr homology 2-binding motifs. J. Biol. Chem. 270:15398-15402.
25. Petch, L.A., S.M. Bockholt, A. Bouton, J.T. Parsons, and K. Burridge. 1995. Adhesion-induced tyrosine phosphorylation of the p130 Src substrate. J. Cell. Sci. 108:1371-1379.
26. Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol. Chem. 270:22259-22262.
27. Miyamoto, S., H. Teramoto, O.A. Coso, J.S. Gutkind, P.D. Burbelo, S.K. Akiyama, and K.M. Yamada. 1995. Integrin function. Molecular hierarchies of cytoskeletal and signaling molecules. J. Cell Biol. 131:791-805.
28. Richardson, A., and J.T. Parsons. 1995. Signal transduction through integrins: a central role for focal adhesion kinase? Bioessays. 17:229-236.
29. Cas. Proc. Natl. Acad. Sci. USA. 92:10678-10682.
30. Sakai, R., A. Iwamatsu, N. Hirano, S. Ogawa, T. Tanaka, H. Mano, Y. Yazaki, and H. Hirai. 1994. A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO (Eur. Mol. Biol. Organ.) J. 13:3748-3756.
31. cas-binding proteins and their role in cellular transformation. Oncogene. 12:2467-2472.
32. FAK. Nature (Lond.). 380: 538-540.
33. 2+ concentration. J. Cell Biol. 131:509-524.
34. FAK phosphorylation in platelets. J. Biol. Chem. 271:16332-16337.
35. cas and its association with c-CrkII. J. Biol. Chem. 271:7796-7801.