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Volumn 158, Issue 7, 1997, Pages 3285-3292

Borrelia burgdorferi Activates Nuclear Factor-κB and Is a Potent Inducer of Chemokine and Adhesion Molecule Gene Expression in Endothelial Cells and Fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; CELL ADHESION MOLECULE; CHEMOKINE; DNA BINDING PROTEIN; I KAPPA B; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPROTEIN; MEMBRANE ANTIGEN; MESSENGER RNA; OUTER MEMBRANE PROTEIN; OUTER SURFACE PROTEIN A;

EID: 0031112560     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (146)

References (49)
  • 2
    • 0011828355 scopus 로고
    • Lyme arthritis: Pathogenetic principles emerging from studies in humans and mice
    • G. S. Panai, ed. Kluwer Academic Publishers, London
    • Simon, M. M., M. D. Kramer, R. Wallich, and U. E. Schaible. 1994. Lyme arthritis: pathogenetic principles emerging from studies in humans and mice. In Immunology of the Connective Tissue Diseases. G. S. Panai, ed. Kluwer Academic Publishers, London, p. 205.
    • (1994) Immunology of the Connective Tissue Diseases , pp. 205
    • Simon, M.M.1    Kramer, M.D.2    Wallich, R.3    Schaible, U.E.4
  • 3
    • 0028052968 scopus 로고
    • Interleukin-8 and related chemotactic cytokines: CXC and CC chemokines
    • Baggiolini, M., B. Dewald, and B. Moser. 1994. Interleukin-8 and related chemotactic cytokines: CXC and CC chemokines. Adv. Immunol. 55:97.
    • (1994) Adv. Immunol. , vol.55 , pp. 97
    • Baggiolini, M.1    Dewald, B.2    Moser, B.3
  • 4
    • 0026095304 scopus 로고
    • Regulation of transendothelial neutrophil migration by endogenous interleukin-8
    • Huber, A. R., S. L. Kunkel, R. F. Todd III, and S. J. Weiss. 1991. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 254: 99.
    • (1991) Science , vol.254 , pp. 99
    • Huber, A.R.1    Kunkel, S.L.2    Todd III, R.F.3    Weiss, S.J.4
  • 6
    • 0029093560 scopus 로고
    • A soluble gradient of endogenous monocyte chemoattractant protein-1 promotes the transendothelial migration of monocytes in vitro
    • Randolph, G. J., and M. B. Furie. 1995. A soluble gradient of endogenous monocyte chemoattractant protein-1 promotes the transendothelial migration of monocytes in vitro. J. Immunol. 155:3610.
    • (1995) J. Immunol. , vol.155 , pp. 3610
    • Randolph, G.J.1    Furie, M.B.2
  • 7
    • 0029559628 scopus 로고
    • C-C chemokines, but not the CXC chemokines interleukin-8 and interferon-γ inducible protein-10, stimulate transendothelial chemotaxis of T lymphocytes
    • Roth, S. J., M. W. Carr, and T. A. Springer. 1995. C-C chemokines, but not the CXC chemokines interleukin-8 and interferon-γ inducible protein-10, stimulate transendothelial chemotaxis of T lymphocytes. Eur. J. Imimmol. 25:3482.
    • (1995) Eur. J. Imimmol. , vol.25 , pp. 3482
    • Roth, S.J.1    Carr, M.W.2    Springer, T.A.3
  • 10
    • 0027511886 scopus 로고
    • Invasion of human skin fibroblasts by the Lyme disease spirochete, Borrelia burgdorferi
    • Klempner, M. S., R. Noring, and R. A. Rogers. 1993. Invasion of human skin fibroblasts by the Lyme disease spirochete, Borrelia burgdorferi. J. Infect. Dis. 167:1074.
    • (1993) J. Infect. Dis. , vol.167 , pp. 1074
    • Klempner, M.S.1    Noring, R.2    Rogers, R.A.3
  • 11
    • 0027205383 scopus 로고
    • 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets
    • 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets. Proc. Natl. Acad. Sci. USA 90:7059.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7059
    • Coburn, J.1    Leong, J.M.2    Erban, J.K.3
  • 12
    • 0028915849 scopus 로고
    • Hemagglutination and proteoglycan binding of the Lyme disease spirochete, Borrelia burgdorferi
    • Leong, J. M., P. E. Morrissey, E. Ortega-Barria, M. E. Pereira, and J. Coburn. 1995. Hemagglutination and proteoglycan binding of the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 63:874.
    • (1995) Infect. Immun. , vol.63 , pp. 874
    • Leong, J.M.1    Morrissey, P.E.2    Ortega-Barria, E.3    Pereira, M.E.4    Coburn, J.5
  • 14
    • 0028277550 scopus 로고
    • Borrelia burgdorferi up-regulates the adhesion molecules E-selectin, P-selectin, ICAM-1 and VCAM-1 on mouse endothelioma cells in vitro
    • Boeggemeyer, E., T. Stehle, U. E. Schaible, M. Hahne, D. Vestweber, and M. M. Simon. 1994. Borrelia burgdorferi up-regulates the adhesion molecules E-selectin, P-selectin, ICAM-1 and VCAM-1 on mouse endothelioma cells in vitro. Cell Adhes. Commun. 2:145.
    • (1994) Cell Adhes. Commun. , vol.2 , pp. 145
    • Boeggemeyer, E.1    Stehle, T.2    Schaible, U.E.3    Hahne, M.4    Vestweber, D.5    Simon, M.M.6
  • 16
    • 0026758170 scopus 로고
    • The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-κB-mediated inhibition
    • Franzoso, G., V. Bours, S. Park, M. Tomita-Yamaguchi, K. Kelly, and U. Siebenlist. 1992. The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-κB-mediated inhibition. Nature 359:339.
    • (1992) Nature , vol.359 , pp. 339
    • Franzoso, G.1    Bours, V.2    Park, S.3    Tomita-Yamaguchi, M.4    Kelly, K.5    Siebenlist, U.6
  • 17
    • 0027997213 scopus 로고
    • A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-κB subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells
    • Franzoso, G., P. Biswas, G. Poli, L. M. Carlson, K. D. Brown, M. Tomita-Yamaguchi, A. S. Fauci, and U. K. Siebenlist. 1994. A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-κB subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells. J. Exp. Med. 180:1445.
    • (1994) J. Exp. Med. , vol.180 , pp. 1445
    • Franzoso, G.1    Biswas, P.2    Poli, G.3    Carlson, L.M.4    Brown, K.D.5    Tomita-Yamaguchi, M.6    Fauci, A.S.7    Siebenlist, U.K.8
  • 19
    • 0027978073 scopus 로고
    • Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: Dependence on lipid modification
    • Weis, J. J., Y. Ma, and L. F. Erdile. 1994. Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modification. Infect. Immun. 62:4632.
    • (1994) Infect. Immun. , vol.62 , pp. 4632
    • Weis, J.J.1    Ma, Y.2    Erdile, L.F.3
  • 21
    • 0028985037 scopus 로고
    • NF-κB and Rel proteins in innate immunity
    • Kopp, E. B., and S. Ghosh. 1995. NF-κB and Rel proteins in innate immunity. Adv. Immunol. 58:1.
    • (1995) Adv. Immunol. , vol.58 , pp. 1
    • Kopp, E.B.1    Ghosh, S.2
  • 22
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
    • Palombella, V. J., O. J. Rando, A. L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78:773.
    • (1994) Cell , vol.78 , pp. 773
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 23
    • 0029010658 scopus 로고
    • The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression
    • Read, M. A., A. S. Neish, F. W. Luscinskas, V. J. Palombella, T. Maniatis, and T. Collins. 1995. The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression. Immunity 2:493.
    • (1995) Immunity , vol.2 , pp. 493
    • Read, M.A.1    Neish, A.S.2    Luscinskas, F.W.3    Palombella, V.J.4    Maniatis, T.5    Collins, T.6
  • 24
    • 0027462682 scopus 로고
    • Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α
    • Brown, K., S. Park, T. Kanno, G. Franzoso, and U. Siebenlist. 1993. Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α. Proc. Natl. Acad. Sci. USA 90:2532.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2532
    • Brown, K.1    Park, S.2    Kanno, T.3    Franzoso, G.4    Siebenlist, U.5
  • 25
    • 0027245086 scopus 로고
    • Cytokine-inducible expression in endothelial cells of an IκB-α-like gene is regulated by NF-κB
    • DeMartin, R., B. Vanhove, Q. Cheng, E. Hofer, V. Csizmadia, H. Winkler, and F. H. Bach. 1993. Cytokine-inducible expression in endothelial cells of an IκB-α-like gene is regulated by NF-κB. EMBO J. 12:2773.
    • (1993) EMBO J. , vol.12 , pp. 2773
    • Demartin, R.1    Vanhove, B.2    Cheng, Q.3    Hofer, E.4    Csizmadia, V.5    Winkler, H.6    Bach, F.H.7
  • 26
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IκB-α: Evidence for an inducible autoregulatory pathway
    • Sun, S.-C., P. A. Ganchi, D. W. Ballard, and W. C. Greene. 1993. NF-κB controls expression of inhibitor IκB-α: evidence for an inducible autoregulatory pathway. Science 259:1912.
    • (1993) Science , vol.259 , pp. 1912
    • Sun, S.-C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 27
    • 0028829239 scopus 로고
    • Borrelia burgdorferi up-regulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro
    • Sellati, T. J., M. J. Burns, M. A. Ficazzola, and M. B. Furie. 1995. Borrelia burgdorferi up-regulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro. Infect. Immun. 63:4439.
    • (1995) Infect. Immun. , vol.63 , pp. 4439
    • Sellati, T.J.1    Burns, M.J.2    Ficazzola, M.A.3    Furie, M.B.4
  • 28
    • 0028609426 scopus 로고
    • Expression of endothelial cell adhesion molecules in joints and heart during Borrelia burgdorferi infection in mice
    • Schaible, U. E., D. Vestweber, E. C. Butcher, T. Stehle, and M. M. Simon. 1994. Expression of endothelial cell adhesion molecules in joints and heart during Borrelia burgdorferi infection in mice. Cell Adhes. Commun. 2:465.
    • (1994) Cell Adhes. Commun. , vol.2 , pp. 465
    • Schaible, U.E.1    Vestweber, D.2    Butcher, E.C.3    Stehle, T.4    Simon, M.M.5
  • 29
    • 0028935791 scopus 로고
    • Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration
    • Springer, T. A. 1995. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57:827.
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 827
    • Springer, T.A.1
  • 30
    • 0029892117 scopus 로고    scopus 로고
    • Orchestrated information transfer underlying leukocyte endothelial interactions
    • Ebnet, K., E. P. Kaldjian, A. O. Anderson, and S. Shaw. 1996. Orchestrated information transfer underlying leukocyte endothelial interactions. Annu. Rev. Immunol. 14:155.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 155
    • Ebnet, K.1    Kaldjian, E.P.2    Anderson, A.O.3    Shaw, S.4
  • 32
    • 0028940959 scopus 로고
    • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages
    • Radolf, J. D., L. L. Arndt, D. R. Akins, L. L. Curetty, M. E. Levi, Y. Shen, L. S. Davis, and M. V. Norgard. 1995. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J. Immunol. 541:2866.
    • (1995) J. Immunol. , vol.541 , pp. 2866
    • Radolf, J.D.1    Arndt, L.L.2    Akins, D.R.3    Curetty, L.L.4    Levi, M.E.5    Shen, Y.6    Davis, L.S.7    Norgard, M.V.8
  • 33
    • 0030048119 scopus 로고    scopus 로고
    • Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease
    • Montgomery, R. R., S. E. Malawista, K. J. M. Feen, and L. K. Bockenstedt. 1996. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. Med. 183:261.
    • (1996) J. Exp. Med. , vol.183 , pp. 261
    • Montgomery, R.R.1    Malawista, S.E.2    Feen, K.J.M.3    Bockenstedt, L.K.4
  • 34
    • 0028024239 scopus 로고
    • Role of outer membrane architecture in immune evasion by Treptmema pallidum and Borrelia burgdorferi
    • Radolf, J. D. 1994. Role of outer membrane architecture in immune evasion by Treptmema pallidum and Borrelia burgdorferi. Trends Microbiol. 2:307.
    • (1994) Trends Microbiol. , vol.2 , pp. 307
    • Radolf, J.D.1
  • 35
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch, R. J., and P. S. Tobias. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 437
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 37
    • 0029782133 scopus 로고    scopus 로고
    • Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-κB
    • Norgard, M. V., L. L. Arndt, D. R. Akins, L. L. Curetty, D. A. Harrich, and J. D. Radolf. 1996. Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-κB. Infect. Immun. 64:3845.
    • (1996) Infect. Immun. , vol.64 , pp. 3845
    • Norgard, M.V.1    Arndt, L.L.2    Akins, D.R.3    Curetty, L.L.4    Harrich, D.A.5    Radolf, J.D.6
  • 38
    • 0028981050 scopus 로고
    • Activation of NF-κ-B requires proteolysis of the inhibitor IκB-α: Signal-induced phosphorylation of IκB-α does not release active NF-κB
    • Lin, Y.-C., K. Brown, and U. Siebenlist. 1995. Activation of NF-κ-B requires proteolysis of the inhibitor IκB-α: signal-induced phosphorylation of IκB-α does not release active NF-κB. Proc. Natl. Acad. Sci. USA 92:552.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 552
    • Lin, Y.-C.1    Brown, K.2    Siebenlist, U.3
  • 39
    • 0028172869 scopus 로고
    • Inducible phosphorylation of IκB-α is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors
    • Finco, T. S., A. A. Beg, and A. S. Baldwin. Jr. 1994. Inducible phosphorylation of IκB-α is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors. Proc. Natl. Acad. Sci. USA 91:11884.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11884
    • Finco, T.S.1    Beg, A.A.2    Baldwin Jr., A.S.3
  • 40
    • 0028986193 scopus 로고
    • NF-κB: A lesson in family values
    • Thanos, D., and T. Maniatis. 1995. NF-κB: a lesson in family values. Cell 80: 529.
    • (1995) Cell , vol.80 , pp. 529
    • Thanos, D.1    Maniatis, T.2
  • 41
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers
    • Collins, T., M. A. Read, A. S. Neish, M. Z. Whitley, D. Thanos, and T. Maniatis. 1995. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers. FASEB J. 9:899.
    • (1995) FASEB J. , vol.9 , pp. 899
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 43
    • 0027453552 scopus 로고
    • Transcription factors NF-κ6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka, T., K. Fujikawa, Y. Nishio, N. Mukaida, K. Matsushima, T. Kishimoto, and S. Akira. 1993. Transcription factors NF-κ6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. USA 90:10193.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10193
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 44
    • 0028137830 scopus 로고
    • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial cells and melanoma cells
    • Shattuck, R. L., L. D. Wood, G. J. Jaffe, and A. Richmond. 1994. MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial cells and melanoma cells. Mol. Cell. Biol. 14:791.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 791
    • Shattuck, R.L.1    Wood, L.D.2    Jaffe, G.J.3    Richmond, A.4
  • 45
    • 0029034506 scopus 로고
    • The interferon-stimulated response element and a κB site mediate synergistic induction of murine IP-10 gene transcription by IFN-γ and TNF-α
    • Ohmori, Y., and T. A. Hamilton. 1995. The interferon-stimulated response element and a κB site mediate synergistic induction of murine IP-10 gene transcription by IFN-γ and TNF-α. J. Immunol. 154:5235.
    • (1995) J. Immunol. , vol.154 , pp. 5235
    • Ohmori, Y.1    Hamilton, T.A.2
  • 46
    • 0027199236 scopus 로고
    • Genomic organization and transcriptional regulation of the RANTES chemokine gene
    • Nelson, P. J., H. T. Kim, W. C. Manning, T. J. Goralski, and A. M. Krensky. 1993. Genomic organization and transcriptional regulation of the RANTES chemokine gene. J. Immunol. 151:2601.
    • (1993) J. Immunol. , vol.151 , pp. 2601
    • Nelson, P.J.1    Kim, H.T.2    Manning, W.C.3    Goralski, T.J.4    Krensky, A.M.5
  • 47
    • 0026013238 scopus 로고
    • 5′ regulatory region of a novel cytokine gene mediates selective activation by interferon-γ
    • Wright, T. M., and J. M. Farber. 1991. 5′ regulatory region of a novel cytokine gene mediates selective activation by interferon-γ. J. Exp. Med. 173:417.
    • (1991) J. Exp. Med. , vol.173 , pp. 417
    • Wright, T.M.1    Farber, J.M.2
  • 48
    • 0028179224 scopus 로고
    • NF-κB and IκB-α: An inducible regulatory system in endothelial activation
    • Read, M. A., M. Z. Whitley, A. J. Williams, and T. Collins. 1994. NF-κB and IκB-α: an inducible regulatory system in endothelial activation. J. Exp. Med. 179:503.
    • (1994) J. Exp. Med. , vol.179 , pp. 503
    • Read, M.A.1    Whitley, M.Z.2    Williams, A.J.3    Collins, T.4
  • 49
    • 0026526503 scopus 로고
    • Tumor necrosis factor a and interferon γ synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-κB-like binding sites of the interleukin 8 gene
    • Yasumoto, K., S. Okamoto, N. Mukaida, S. Murakami, M. Mai, and K. Matsushima. 1992. Tumor necrosis factor a and interferon γ synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-κB-like binding sites of the interleukin 8 gene. J. Biol. Chem. 267:22506.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22506
    • Yasumoto, K.1    Okamoto, S.2    Mukaida, N.3    Murakami, S.4    Mai, M.5    Matsushima, K.6


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