Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)

EMBO Journal

Volumn 18, Issue 21, 1999, Pages 6037-6049

  Torii, Seiji ^a   Egan, David A ^b   Evans, Ronald A ^b   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Caspase activation; Fas induced apoptosis; hDaxx; PML oncogenic domains

Indexed keywords

ARSENIC TRIOXIDE; FAS ANTIGEN; NUCLEAR PROTEIN; ONCOPROTEIN; PHOSPHOTRANSFERASE;

APOPTOSIS; ARTICLE; CYTOSOL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD95; APOPTOSIS; ARSENICALS; CARRIER PROTEINS; CELL LINE; CELL NUCLEUS; CLONING, MOLECULAR; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; NUCLEAR PROTEINS; OXIDES; PRECIPITIN TESTS; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; YEASTS;

EID: 0033229827     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.21.6037     Document Type: Article

References (52)

1. Ahmad, M., Srinivasula, S.M., Wang, L., Talanian, R.V., Litwack, G., Fernandes-Alnemri, T. and Alnemri, E.S. (1997) CRADD, a novel human apoptotic adaptor molecule for caspase-2 and FasL/tumor necrosis factor receptor-interacting protein RIP. Cancer Res., 57, 615-619.
2. Armstrong, R. et al. (1996) Fas-induced activation of the cell death related protease CPP32 is inhibited by Bcl-2 and by ICE family protease inhibitors. J Biol. Chem., 271, 16850-16855.
3. Bennett, M., Macdonald, K., Chan, S., Luzio, J., Simari, R. and Weissberg, P. (1998) Cell surface trafficking of fas: A rapid mechanism of p53-mediated apoptosis. Science, 282, 290-293.
4. Boldin, M.P., Varfolomeev, E.E., Pancer, Z., Mett, I.L., Camonis, J.H. and Wallach, D. (1995) Self-association of the 'death domains' of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J. Biol. Chem., 270, 7795-7798.
5. Cardone, M., Roy, N., Stennicke, H., Salvesen, G., Franke, T., Stanbridge, E., Frisch, S. and Reed, J. (1998) Regulation of cell death protease caspase-9 by phosphorylation. Science, 282, 1318-1320.
6. Chang, H., Nishitoh, H., Yang, X., Ichijo, H. and Baltimore, D. (1998) Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein daxx. Science, 281, 1860-1863.
7. Chang, H., Yang, X. and Baltimore, D. (1999) Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activiation. Proc. Natl Acad. Sci. USA, 96, 1252-1256.
8. 4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/ PML proteins. Blood, 88, 1052-1061.
9. Chen, J., Umesono, K. and Evans, R. (1996b) Bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proc. Natl Acad. Sci. USA, 93, 7567-7571.
10. de The, H., Lavau, C., Marchio, A., Chomienne, C., Degos, L. and Dejean, A. (1991) The PML-RAR α fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell, 66, 675-684.
11. Doucas, V., Tini, M., Egan, D. and Evans, R. (1999) Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling. Proc. Natl Acad. Sci. USA, 96, 2627-2632.
12. Duan, H. and Dixit, V.M. (1997) RAIDD is a new 'death' adaptor molecule. Nature, 385, 86-89.
13. Dyck, J., Maul, G., Miller, W., Chen, J., Kakizuka, A. and Evans, R. (1994) A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell, 76, 333-343.
14. Fernandes-Alnemri, T. et al. (1996) In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl Acad. Sci. USA, 93, 7464-7469.
15. Frisch, S.M., Vuori, K., Kelaita, D. and Sicks, S. (1996) A role for JunN-terminal kinase in anoikis; suppression by bcl-2 and crmA. J. Cell Biol., 135, 1377-1382.
16. Green, D. and Reed, J. (1998) Mitochondria and apoptosis. Science, 281, 1309-1312.
17. Guiochon-Mantel, A., Savouret, J., Quignon, F., Delabre, K., Milgrom, E. and de The, H. (1995) Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors. Mol. Endocrinol., 9, 1791-1803.
18. Hibi, M., Lin, A., Smeal, T., Minden, A. and Karin, M. (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev., 7, 2135-2148.
19. Kakizuka, A., Miller, W., Umesono, K., Warrell, R., Frankel, S., Murty, V., Dmitrovsky, E. and Evans, R. (1991) Chromosomal translocation t (15; 17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell, 66, 663-674.
20. Kiriakidou, M., Driscoll, D.A., Guisa, J.M.L. and Strauss, J.F., III (1997) Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region. DNA Cell Biol., 16, 1289-1298.
21. Knudson, C.M., Tung, K.S.K., Tourtellotte, W.G., Brown, G.A.J. and Korsmeyer, S.J. (1995) Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science, 270, 96-99.
22. Krajewska, M., Wang, H.-G., Krajewski, S., Zapata, J.M., Shabaik, A., Gascoyne, R. and Reed, J.C. (1997) Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease. Cancer Res., 57, 1605-1613.
23. Krajewski, S., Zapata, J.M. and Reed, J.C. (1996) Detection of multiple antigens on Western blots. Anal. Biochem., 236, 221-228.
24. Lamond, A. and Earnshaw, W. (1998) Structure and function in the nucleus. Science, 280, 547-553.
25. La Morte, V., Dyck, J., Ochs, R. and Evans, R. (1998) Localization of nascent RNA and CREB binding protein with the Pml-containing nuclear body. Proc. Natl Acad. Sci. USA, 95, 4991-4996.
26. Li, H., Zhu, H., Xu, C. and Yuan, J. (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell, 94, 491-501.
27. Luo, X., Budihardjo, I., Zou, H., Slaughter, C. and Wang, X. (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell, 94, 481-490.
28. Mannick, J.B., Hausladen, A., Liu, L.M., Hess, D.T., Zeng, M., Miao, Q.X., Kane, L.S., Gow, A.J. and Stamler, J.S. (1999) Fas-induced caspase denitrosylation. Science, 284, 651-654.
29. Matsuzawa, S., Takayama, S., Froesch, B.A., Zapata, J.M. and Reed, J.C. (1998) p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1. EMBO J., 17, 2736-2747.
30. Michaelson, J.S., Bader, D., Kuo, F., Kozak, C. and Leder, P. (1999) Loss of daxx, a promiscuously interaction protein, results in extensive apoptosis in early mouse development. Genes Dev., 13, 1918-1923.
31. Middleton, G., Nunez, G. and Davies, A.M. (1996) Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors. Development, 122, 695-701.
32. Mu, Z., Chin, K., Liu, J., Lozano, G. and Chang, K. (1994) PML, a growth suppressor disrupted in acute promyelocytic leukemia. Mol. Cell. Biol., 14, 6858-6867.
33. Muller, S., Matunis, M.J. and Dejean, A. (1998) Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J., 17, 61-70.
34. Muzio, M. et al. (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell, 85, 817-827.
35. Oh, J.H., O'Malley, L.K., Krajewski, S., Reed, J.C. and Oh, Y.J. (1997) Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death. Neuroreport, 8, 1851-1856.
36. Okura, J., Gong, L., Kamitani, T., Wada, T., Okura, I., Wei, C.F., Chang, H.M. and Yeh, E.T. (1996) Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. J. Immunol., 157, 4277-4281.
37. Perez, D. and White, E. (1998) E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. J. Cell Biol., 141, 1255-1266.
38. Pluta, A., Earnshaw, W. and Goldberg, I. (1998) Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death. J. Cell Sci., 111, 2029-2041.
39. Quignon, F., De Bels, F., Koken, M., Feunteun, J., Ameisen, J.-C. and de Thé, H. (1998) Pml induces a novel caspase-independent death process. Nature Genet., 20, 259-265.
40. Reed, J.C. (1997) Cytochrome c: Can't live with it; can't live without it. Cell, 91, 559-562.
41. Salvesen, G.S. and Dixit, V.M. (1997) Caspases: Intracellular signaling by proteolysis. Cell, 91, 443-446.
42. Siegel, R., Martin, D., Zheng, L., Ng, S., Bertin J., Cohen J. and Lenardo, M. (1998) Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis. J. Cell Biol., 141, 1243-1253.
43. Soignet, S. et al. (1998) Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N. Engl. J. Med., 339, 1341-1348.
44. Stennicke, H. et al. (1998) Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem., 273, 27084-27090.
45. Sternsdorf, T., Jensen, K. and Will, H. (1997) Evidence for covalent modification of the nuclear Dot-associated proteins PML and Sp100 by PICI/SUMO-1. J. Cell Biol., 139, 1621-1634.
46. Vallian, S., Gäken, J., Trayner, I., Gingold, E., Kouzarides, J., Chang, K.-S. and Farzaneh, F. (1997) Transcriptional repression by the promyelocytic leukemia protein, PML. Exp. Cell Res., 237, 371-382.
47. Wallach, D., Boldin, M., Varfolomeev, E., Beyaert, R., Vandenabeele, P. and Fiers, W. (1997) Cell death induction by receptors of the TNF family: towards a molecular understanding. FEBS Lett., 410, 96-106.
48. Wang, Z., Delva, L., Gaboli, M., Rivi, R., Giorgio, M., Cordon-Cardo, C., Grosveld, F.P. and Pandolfi, P. (1998a) Role of PML in cell growth and the retinoic acid pathway. Science, 279, 1547-1551.
49. Wang, Z.-G., Ruggero, D., Ronchetti, S., Zhong, S., Gaboli, M., Rivi, R. and Pandolfi, P. (1998b) Pml is essential for multiple apoptotic pathways. Nature Genet., 20, 266-272.
50. Yang, X., Khosravi-Far, R., Chang, H.Y. and Baltimore, D. (1997) Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell, 89, 1067-1076.
51. Zhou, Q., Snipas, S., Orth, K., Muzio, M., Dixit, V.M. and Salvesen, G.S. (1997) Target protease specificity of the viral serpin CrmA: analysis of five caspases. J. Biol. Chem., 272, 7797-7800.
52. Zhu, J., Koken, M., Frederique, Q., Chelbi-Alix, M., Degos, L., Wang, Z., Chen, Z. and de The, H. (1997) Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia. Proc. Natl Acad. Sci. USA, 94, 3978-3983.