Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death

Journal of Cell Science

Volumn 111, Issue 14, 1998, Pages 2029-2041

  Pluta, Ann F ^a,b   Earnshaw, William C ^a,c   Goldberg, Ilya G ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d HARVARD UNIVERSITY   (United States)

Author keywords

CENP C; HDaxx; Interphase centromere

Indexed keywords

FAS ANTIGEN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL DEATH; CENTROMERE; CHROMOSOME SEGREGATION; INTERPHASE; MITOSIS; NONHUMAN; PRIORITY JOURNAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD95; APOPTOSIS; BASE SEQUENCE; CARRIER PROTEINS; CELL NUCLEUS; CENTROMERE; CHROMOSOMAL PROTEINS, NON-HISTONE; GENE LIBRARY; HELA CELLS; HUMANS; INTERPHASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOSIS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

MURINAE;

EID: 0031847605     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Allshire, R. C. (1997) Centromeres, checkpoints and chromatid cohesion. Curr. Opin. Genet Dev. 7, 264-273.
2. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-10.
3. Brenner, S., Pepper, D., Berns, M. W., Tan, E. and Brinkley, B. R. (1981). Kinetochore structure, duplication and distribution in mammalian cells: analysis by human autoantiboies from scleroderma patients. J. Cell Biol. 91, 95-102.
4. Brinkley, B. R., Ouspenski, I. and Zinkowski, R. P. (1992). Structure and molecular organization of the centromere-kinetochore complex. Trends Cell Biol. 2, 15-21.
5. Brown, M. T. (1995). Sequence similarities between the yeast chromosome segregation protein Mif2 and the mammalian centromere protein CENP-C. Gene 160, 111-116.
6. Campbell, M. S. and Gorbsky, G. J. (1995) Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase. J. Cell Biol. 129, 1195-1204.
7. Casiano, C. A., Landberg, G., Ochs, R. L. and Tan, E. M. (1993) Autoantibodies to a novel cell cycle-regulated protein that accumulates in the nuclear matrix during S phase and is localized in the kinetochores and spindle midzone during mitosis. J. Cell Sci. 1993, 106.
8. Chomezynski, P. (1996). Guanidine methods for total RNA preparation. In Current Protocols in Molecular Biology (ed. F. A. Ausubel. R. Brent. R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith and K. Struhl) pp. 4.2.3-4.2.4. New York: John Wiley & Sons.
9. Cooke, C. A., Bernat, R. L. and Earnshaw, W. C. (1990). CENP-B: A major human centromere protein located beneath the kinetochore. J. Cell Biol. 110, 1475-1488.
10. Earnshaw, W. C. and Rothfield, N. (1985). Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma 91, 313-321.
11. Earnshaw, W. C. (1987). Anionic regions in nuclear proteins. J. Cell Biol. 105, 1479-1482.
12. Earnshaw, W. C., Sullivan, K. F., Machlin, P. S., Cooke, C. A., Kaiser, D. A., Pollard, T. D., Rothfield, N. F. and Cleveland, D. W. (1987) Molecular cloning of cDNA for CENP-B. the major human centromere autoantigen. J. Cell Biol. 104, 817-829.
13. Earnshaw, W. C., Ratrie, H. and Stetten, G. (1989) Visualisation of centromere proteins CENP-B and CENP-C on a stable dicentric chromosome in cytological spreads. Chromosoma (Berl.). 98, 1-12.
14. Earnshaw, W. C., Bernat, R. L., Cooke, C. A. and Rothfield, N. F. (1991) Role of the centromere/ kinetochore in cell cycle control. Cold Spring Harbor Symp. Quant. Biol. 56, 675-685.
15. Earnshaw, W. C. and Cooke, C. A. (1991). Analysis of the distribution of the INCENPs throughout mitosis reveals the existence of three distinct substages of metaphase and early events in cleavage furrow formation. J. Cell Sci. 98, 443-461.
16. Earnshaw, W. C. and Rattner, J. B. (1991). The use of autoantibodies in the study of nuclear and chromosomal organization. Meth. Cell Biol. 35, 135-175.
17. Feinberg, A. P. and Vogelstein, B. (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
18. Fukagawa, T. and Brown, W. R. A. (1997). Efficient conditional mutation of the vertebrate CENP-C gene Hum. Mol. Genet. 6, 2301-2308.
19. Golemis, E. A. and Brent, R. (1992). Fused protein domains inhibit DNA binding by LexA. Mol. Cell. Biol. 12, 3006-3014.
20. Golemis, E., Gyuris, J. and Brent, R. (1996). Interaction trap/two-hybrid system to identity interacting proteins. In Current Protocols in Moleeular Biology (ed. F. A. Ausubel. R. Brent, R. F. Kingston, D. D. Moore, J. G Seidman, J. A. Smith and K. Struhl). pp. 20.1.1-20.1. 28. New York: John Wiley & Sons.
21. Gyuris, J., Golemis, E., Chertkov, H. and Brent, R. (1993). Cdil, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75, 791-803.
22. Halverson, D., Baum, M., Stryker, J., Carbon, J. and Clarke, L. (1997) A centromere DNA binding protein from fission yeast affects chromosome segregation and has homology to human CENP-B. J. Cell Biol. 136, 487-500.
23. Kalitsis, P., Fowler, K. J., Earle, E., Hill, J. and Choo, K. H. A. (1998) Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death. Proc. Nat. Acad. Sci. USA 95, 1136-1141.
24. Kapoor, M., Montes de Oca Luna, R., Lozano, G., Cummings. C., Brinkley, B. R. and May, G. S. (1997). The CENP-B gene is not essential in mice. Mol. Biol. Cell 8, 267a.
25. Kiriakidou, M., Driscoll, D. A., Lopez-Guisa, J. M. and Strauss, J. F. I. (1997). Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region. DNA Cell Biol. 16, 1289-1298.
26. knehr, M., Poppe, M., Schroetecr, D., Eickelbaum, W., Finze, E.-M., Kiesewetter, U.-L., Enulescu, M., Arand, M. and Paweletz, N. (1996) Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G1 phase. Proc. Nat. Acad. Sci. USA 93, 10234-10239.
27. Lanini, L. and McKeon, F. (1995). Domains required for CENP-C assembly at the kinetochore. Mol. Biol. Cell 6, 1049-1059.
28. Lee, J.-K., Huberman, J. A. and Hurwitz, J. (1997) Purification and characterization of a CENP-B homologue protein that hinds to the centromeric K-type repeat DNA ot Schizosaccharomyces pombe. Proc. Nat. Acad. Sci. USA 94, 8427-8432.
29. Li, J., Xu, M., Zhou, H., Ma, J. and Potter, H. (1997). Alzhemier presenilins in the nuclear membrane, inierphase kmetochores, and centrosomes suggest a role in chromosome segregation. Cell 90, 917-927.
30. Li, Y. and Benezra, R. (1996). Identification of a human mitotic checkpoint gene:hsMAD2. Science 274, 246-248.
31. Lupas, A. (1996). Prediction and analysis of coiled-coil structures. Meth. Enzzymol. 266, 513-525.
32. Mackay, A., Eckley, D. M., Chue, C. and Earnshaw, W. C. (1993) Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase. J. Cell Biol. 123, 373-385.
33. Matsumoto, H., Masukata, H., Muro, Y., Nozaki, N. and Okazaki, T. (1989a). A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA. a human centromeric satellite. J. Cell Biol. 109, 1963-1973.
34. Matsumoto, H., Sugimoto, K. and Okazaki, T. (1989b). Alphoid satellite DNA is tightly associated with centromere antigens in human chromosomes throughout the cell cycle. Exp. Cell Res. 181, 181-196.
35. Matsumoto, H., Yoda, K., Ikeno, M., Kitagawa, K., Muro, Y. and Okazaki, T. (1993). Properties of CENP-B and its target sequence in a satellite DNA. In Chromosome Segregation and Anneuplody (ed. B. K. Vig). pp. 31-43. Berlin: Springer-Verlag.
36. Meluh, P. B. and Koshland, D. (1995) Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol. Biol. Cell 6, 793-807.
37. Monteiro, M. J. and Mical, T. I. (1996). Resolution of kinase activities during the HeLa cell cycle: Identification of kinases with cyclic activities. Exp. Cell Res. 223, 443-451.
38. Moroi, Y., Peebles, C., Fritzler, M. J., Steigerwald, J. and Tan, K. M. (1980). Autoantibody to centromere (kinetochore) in scleroderma sera. Proc. Nat. Acad. Sci. USA 77, 1627-1631.
39. Moroi, Y., Hartman, A. L., Nakane, P. K. and Tan, F. M. (1981) Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. J. Cell Biol. 90, 254-259.
40. Nakai, K. and Kanehisa, M. (1992). A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14, 897-911.
41. Ochs, R. L. and Press, R. I. (1992). Centromere autoantigens are associated with the nucleolus. Exp. Cell Res. 200, 339-350.
42. Page, S. L., Earnshaw, W. C., Choo, K. H. A. and Shaffer, L. G. (1995) Further evidence that CENP-C is a necessary component of active centromeres: studies of a dic(X:15) with simultaneous immunofluorescence and FISH. Hum. Mol. Genet. 4, 289-294.
43. Pluta, A. F., Saitoh, N., Goldberg, I. and Earnshaw, W. C. (1992) Identification of a subdomam of CENP-B that is necessary and sufficient for localization to the human centromere. J. Cell Biol. 116, 1081-1093.
44. Pluta, A. F., Mackay, A. M., Ainsztein, A. M., Goldberg, I. G. and Earnshaw, W. C. (1995). The centromere: hub of chromosomal activities. Science 270, 1591-1594.
45. Pluta, A. F. and Earnshaw, W. C. (1996). Specific interaction between human kinetochore protein CENP-C and a nucleolar transcriptional regulator. J. Biol. Chem. 271, 18767-18774.
46. Rattner, J. B., Rao, A., Fritzler, M. J., Valencia, D. W. and Yen, T. J. (1993). CENP-F is a.ca 400 kDa kinetochore protein that exhibits, a cell-cycle dependent localization. Cell Motil. Cytoskel. 26, 214-226.
47. Reynolds, A. and Lundblad, V. (1989) Yeast vectors and assays tor expression of cloned genes. In Current Protocols in Molecular Biology (ed. F. A. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith and K. Struhl), pp. 13.6.1-13.6.4. New York: John Wiles & Sons.
48. Saitoh. H., Tomkiel, J., Cooke, C. A., Ratrie III. H., Maurer, M., Rothfield, N. F. and Earnshaw, W. C. (1992). CENP-C. an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70, 115-125.
49. Schaar, B. T., Chan, G. K. T., Maddox, R. Salmon, E. D. and Yen, T. J. (1997) CENP-E function at kinetochores is essential for chromosome alignment. J. Cell Biol. 139, 1373-1382.
50. Stoler S., Keith, K. C., Curnick, K. E. and Fitzgerald-Hayes, M. (1995) A mutation in CSE4. an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes Dev. 9, 573-586.
51. Sugimoto, K., Kuriyama, K., Shibata, A. and Himeno, M. (1997). Characterization of internal DNA-binding and C-terminal dimenzation domains of human centromere/kinetochore autoantigen CENP-C in vitro: role of DNA-hinding and self-associating activities in kinetochore organization. Chromosome Rev. 5, 132-141.
52. Sullivan, B. A. and Schwartz, S. (1995). Identification of centromeric antigens in dicentric Robertsoman translocations: CENP-C and CENP-E. are necessary components of functional centromeres. Hum. Mol. Genet. 4. 2189-2197.
53. Sullivan, K. F., Hechenberger, M. and Masri, K. (1994) Human CENP-A contains a histone H3 related histone fold domain that is required tor targeting to the centromere. J. Cell Biol. 127. 581-592.
54. Tan, E. M., Chan, E. K. L., Sullivan, K. F. and Rubin, R. L. (1988). Antinuclear antibodies (ANAs) diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity. Clin. Immunul. Immunopathol. 47, 121-141.
55. Taylor, S. S. and McKeon, F. (1997). Kinetochore localization of murine Bub1 is required tor normal mitotic timing and checkpoint response to spindle damage. Cell 89, 727-735.
56. Tomkiel, J., Cooke, C. A., Saitoh, H., Bernat, R. L. and Earnshaw, W. C. (1994). CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J. Cell Biol. 125, 531-545.
57. Wajant, H., Johannes, F.-J., Haas, E., Siemienski, K., Schwenzer, R., Schubert, G., Weiss, T., Grell, M. and Scheurich, P. (1998). Dominant-negative FADD inhibits TNFR60-. Fas/Apol- and TRAIL.-R/Apo2-mediated cell death but not gene induction. Curr. Biol. 8. 113-116.
58. Warburton, P., Cooke, C. A., Bourassa, S., Vafa, O., Sullivan, B. A., Stetten, G., Gimelli, G., Warburton, D., Tyler-Smith. C., Sullivan, K. F., Poirer, G. G. and Earnshaw, W. C. (1997) Immunolocalization of CENPA suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr. Biol. 7, 901-904.
59. Wood, K. W., Sakowicz, R., Goldstein, L. S. B. and Cleveland, D. W. (1997). CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell 91, 357-366.
60. Wordeman, L., Steurer, E., Sheetz, M. and Mitchison, T. (1991). Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. J. Cell Biol. 114, 285-294.
61. Wordeman, L. and Mitchison, T. J. (1995). Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128, 95-105.
62. Yang, C. H., Tomkiel, J., Saitoh, H., Johnson, D. H. and Earnshaw, W. C. (1996). Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetoehore protein CENP-C. Mol. Cell. Biol. 16, 3576-3586.
63. Yang, X., Khosravi-Far, R., Chang, H. Y. and Baltimore, D. (1997) Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89, 1067-1076.
64. Zervos, A. S., Gyuris, J. and R., B. (1993). Mxil, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72, 223-232.
65. Zhang, J., Cado, D., Chen, A., Kabra, N. H. and Winoto, A. (1998) Fas-mediated apoptosis and activation-induced T-cell proliteration are defective in mice lacking FADD/Mort1. Nature 392, 296-299.
66. Zhu, X., Mancini, M. A., Chang, K.-H., Liu, C.-Y., Chen, C.-F., Shan, B., Jones, D., Yang-Feng, T. L. and Lee, W.-H. (1995). Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Mol. Cell. Biol. 15, 5017-5029.