-
1
-
-
0031873505
-
Inhibition of apoptotic signaling pathways in cancer cells as a mechanism of chemotherapy resistance
-
Haq, R., and Zanke, B. Inhibition of apoptotic signaling pathways in cancer cells as a mechanism of chemotherapy resistance. Cancer Metastasis Rev., 2: 233-239, 1998.
-
(1998)
Cancer Metastasis Rev.
, vol.2
, pp. 233-239
-
-
Haq, R.1
Zanke, B.2
-
2
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539-542, 1994.
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
3
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Washington DC
-
Lowe, S. W., Bodis, S., McClatchey, A., Remington, L., Ruley, H. E., Fisher, D. E., Housman, D. E., and Jacks, T. p53 status and the efficacy of cancer therapy in vivo. Science (Washington DC), 266: 807-810, 1994.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
4
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Lond.
-
Graeber, T. G., Osmanian, C. Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., and Giaccia, A. J. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature (Lond.), 379: 88-91, 1996.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
5
-
-
0031918244
-
Regulation of proliferation-survival decisions during tumor cell hypoxia
-
Schmaltz, C., Hardenbergh, P. H., Wells, A., and Fisher, D. E. Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol. Cell. Biol., 18: 2845-2854, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2845-2854
-
-
Schmaltz, C.1
Hardenbergh, P.H.2
Wells, A.3
Fisher, D.E.4
-
6
-
-
0032487926
-
Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation?
-
Magnusson, K. P., Satalino, R., Qian, W., Klein, G., and Wiman, K. G. Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation? Oncogene, 17: 2333-2337, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 2333-2337
-
-
Magnusson, K.P.1
Satalino, R.2
Qian, W.3
Klein, G.4
Wiman, K.G.5
-
7
-
-
0029776580
-
Apoptosis resistance increases with metastatic potential in cells of the human LNCaP prostate carcinoma line
-
McConkey, D. J., Greene, G., and Pettaway, C. A. Apoptosis resistance increases with metastatic potential in cells of the human LNCaP prostate carcinoma line. Cancer Res., 56: 5594-5599, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 5594-5599
-
-
McConkey, D.J.1
Greene, G.2
Pettaway, C.A.3
-
8
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Washington DC
-
Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R., and Greenberg, M. E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (Washington DC), 275: 661-665, 1997.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
9
-
-
0031026324
-
Neurotrophin-3 promotes the survival of oligodendrocyte precursors in embryonic hippocampal cultures under chemically defined conditions
-
Bertollini, L., Ciotti, M. T., Cherubini, E., and Cattaneo, A. Neurotrophin-3 promotes the survival of oligodendrocyte precursors in embryonic hippocampal cultures under chemically defined conditions. Brain Res., 746: 19-24, 1997.
-
(1997)
Brain Res.
, vol.746
, pp. 19-24
-
-
Bertollini, L.1
Ciotti, M.T.2
Cherubini, E.3
Cattaneo, A.4
-
10
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke, T. F., Kaplan, D. R., and Cantley, L. C. PI3K: downstream AKTion blocks apoptosis. Cell, 88: 435-437, 1997.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
11
-
-
0031034574
-
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
-
Kulik, G., Klippel, A., and Weber, M. J. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell Biol., 17: 1595-1606, 1997.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 1595-1606
-
-
Kulik, G.1
Klippel, A.2
Weber, M.J.3
-
12
-
-
0028263811
-
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
-
Harrington, E. A., Bennett, M. R., Fanidi, A., and Evan, G. I. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J., 13: 3286-3295, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 3286-3295
-
-
Harrington, E.A.1
Bennett, M.R.2
Fanidi, A.3
Evan, G.I.4
-
13
-
-
0029670038
-
Suppression of interleukin-1β-converting enzyme-mediated cell death by insulin-like growth factor
-
Jung, Y., Miura, M., and Yuan, J. Suppression of interleukin-1β-converting enzyme-mediated cell death by insulin-like growth factor. J. Biol. Chem., 271: 5112-5117, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5112-5117
-
-
Jung, Y.1
Miura, M.2
Yuan, J.3
-
14
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., Rodriguez-Viciana, P., Wennstrom, S., Warne, P. H., and Downward, J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J., 16: 2783-2793, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
15
-
-
0027320668
-
Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin
-
Muta, K., and Krantz, S. B. Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin. J. Cell Physiol., 156: 264-271, 1993.
-
(1993)
J. Cell Physiol.
, vol.156
, pp. 264-271
-
-
Muta, K.1
Krantz, S.B.2
-
16
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
Alessi, D. R., and Cohen, P. Mechanism of activation and function of protein kinase B. Curr. Opin. Genet. Dev., 8: 55-62, 1998.
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 55-62
-
-
Alessi, D.R.1
Cohen, P.2
-
17
-
-
0029810181
-
Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
-
Kohn, A. D., Takeuchi, F., and Roth, R. A. Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J. Biol. Chem., 271: 21920-21926, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21920-21926
-
-
Kohn, A.D.1
Takeuchi, F.2
Roth, R.A.3
-
18
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi, D. R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P., and Hemmings, B. A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J., 15: 6541-6551, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
19
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Washington DC
-
Stokoe, D., Stephens, L. R., Copeland, T., Gaffney, P. R., Reese, C. B., Painter, G. F., Holmes, A. B., McCormick, F., and Hawkins, P. T. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science (Washington DC), 277: 567-570, 1997.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
20
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
Washington DC
-
del Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., and Nunez, G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science (Washington DC), 278: 687-689, 1997.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Del Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
21
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell, 91: 231-241, 1997.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
22
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Washington DC
-
Cardone, M. H., Roy, N., Stennicke, H. R., Salvesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S., and Reed, J. C. Regulation of cell death protease caspase-9 by phosphorylation. Science (Washington DC), 282: 1318-1321, 1998.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
23
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic, V., Suzuki, A., de la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P., and Mak, T. W. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell, 95: 29-39, 1998.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
24
-
-
0032482369
-
PTEN/MMAC1/TEP1 involvement in primary prostate cancers
-
Pesche, S., Lati, A., Muzeau, F., Cussenot, O., Fournier, G., Longy, M., Eng, C., and Lidereau, R. PTEN/MMAC1/TEP1 involvement in primary prostate cancers. Oncogene, 16: 2879-2883, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 2879-2883
-
-
Pesche, S.1
Lati, A.2
Muzeau, F.3
Cussenot, O.4
Fournier, G.5
Longy, M.6
Eng, C.7
Lidereau, R.8
-
25
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression
-
USA
-
Whang, Y. E., Wu, X., Suzuki, H., Reiter, R. E., Tran, C., Vessella, R. L., Said, J. W., Isaacs, W. B., and Sawyers, C. L. Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression. Proc. Natl. Acad. Sci. USA, 95, 5246-5250, 1998.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
Reiter, R.E.4
Tran, C.5
Vessella, R.L.6
Said, J.W.7
Isaacs, W.B.8
Sawyers, C.L.9
-
26
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vlietstra, R. J., van Alewijk, D. C., Hermans, K. G., van Steenbrugge, G. J., and Trapman, J. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res., 58: 2720-2723, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 2720-2723
-
-
Vlietstra, R.J.1
Van Alewijk, D.C.2
Hermans, K.G.3
Van Steenbrugge, G.J.4
Trapman, J.5
-
27
-
-
15444349266
-
Frequent inactivation of PTEN/ MMAC1 in primary-prostate cancer
-
Cairns, P., Okami, K., Halachmi, S., Halachmi, N., Esteller, M., Herman, J. G., Jen, J., Isaacs, W. B., Bova, G. S., and Sidransky, D. Frequent inactivation of PTEN/ MMAC1 in primary-prostate cancer. Cancer Res., 5: 4997-5000, 1997.
-
(1997)
Cancer Res.
, vol.5
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
Halachmi, N.4
Esteller, M.5
Herman, J.G.6
Jen, J.7
Isaacs, W.B.8
Bova, G.S.9
Sidransky, D.10
-
28
-
-
0032145501
-
Development of an androgen receptor-null model for identifying the initiation site for androgen stimulation of proliferation and suppression of programmed (apoptotic) death of PC-82 human prostate cancer cells
-
Gao, J., and Isaacs, J. T. Development of an androgen receptor-null model for identifying the initiation site for androgen stimulation of proliferation and suppression of programmed (apoptotic) death of PC-82 human prostate cancer cells. Cancer Res., 58: 3299-3306, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 3299-3306
-
-
Gao, J.1
Isaacs, J.T.2
-
29
-
-
0029151180
-
Lobe-specific apoptotic cell death in rat prostate after androgen ablation by castration
-
Banerjee, P. P., Banerjee, S., Tilly, K. I., Tilly, J. L., Brown, T. R., and Zirkin, B. R. Lobe-specific apoptotic cell death in rat prostate after androgen ablation by castration. Endocrinology, 136: 4368-4376, 1995.
-
(1995)
Endocrinology
, vol.136
, pp. 4368-4376
-
-
Banerjee, P.P.1
Banerjee, S.2
Tilly, K.I.3
Tilly, J.L.4
Brown, T.R.5
Zirkin, B.R.6
-
30
-
-
0030772022
-
Target to apoptosis: A hopeful weapon for prostate cancer
-
Tang, D. G., and Porter, A. T. Target to apoptosis: a hopeful weapon for prostate cancer. Prostate, 32: 284-293, 1997.
-
(1997)
Prostate
, vol.32
, pp. 284-293
-
-
Tang, D.G.1
Porter, A.T.2
-
31
-
-
0024373929
-
Treatment of prostate cancer
-
Korman, L. B. Treatment of prostate cancer. Clin. Pharm., 8: 412-424, 1989.
-
(1989)
Clin. Pharm.
, vol.8
, pp. 412-424
-
-
Korman, L.B.1
-
32
-
-
0018847558
-
The LNCaP cell line - A new model for studies on human prostatic carcinoma
-
Horoszewicz, J. S., Leong, S. S., Chu, T. M., Wajsman, Z. L., Friedman, M., Papsidero, L., Kim, U., Chai, L. S., Kakati, S., Arya, S. K., and Sandberg, A. A. The LNCaP cell line - a new model for studies on human prostatic carcinoma. Prog. Clin. Biol. Res., 37: 115-132, 1980.
-
(1980)
Prog. Clin. Biol. Res.
, vol.37
, pp. 115-132
-
-
Horoszewicz, J.S.1
Leong, S.S.2
Chu, T.M.3
Wajsman, Z.L.4
Friedman, M.5
Papsidero, L.6
Kim, U.7
Chai, L.S.8
Kakati, S.9
Arya, S.K.10
Sandberg, A.A.11
-
33
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation, and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation, and independently of mitochondrial transmembrane depolarization. EMBO J., 17: 37-49, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
34
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91: 479-489, 1997.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
35
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem, R., Hakem, A., Duncan, G. S., Henderson, J. T., Woo, M., Soengas, M. S., Elia, A., de la Pompa, J. L., Kagi, D., Khoo, W., Potter, J., Yoshida, R., Kaufman, S. A., Lowe, S. W., Penninger, J. M., and Mak, T. W. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell, 94: 339-352, 1998.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
36
-
-
0031770827
-
Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I
-
Kulik, G., and Weber, M. J. Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I. Mol. Cell. Biol. 18: 6711-6718, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6711-6718
-
-
Kulik, G.1
Weber, M.J.2
-
37
-
-
0029156587
-
In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin
-
Schultz, R. M., Merriman, R. L., Andis, S. L., Bonjouklian, R., Grindey, G. B., Rutherford, P. G., Gallegos, A., Massey, K., and Powis, G. In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin. Anti-cancer Res., 15: 1135-1139, 1995.
-
(1995)
Anti-Cancer Res.
, vol.15
, pp. 1135-1139
-
-
Schultz, R.M.1
Merriman, R.L.2
Andis, S.L.3
Bonjouklian, R.4
Grindey, G.B.5
Rutherford, P.G.6
Gallegos, A.7
Massey, K.8
Powis, G.9
-
38
-
-
0032575752
-
Mitochondria and apoptosis
-
Washington DC
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Washington DC), 281: 1309-1312, 1998.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
|