메뉴 건너뛰기




Volumn 140, Issue 2, 1999, Pages 111-129

Oestrogen deficiency in men: Where are we today?

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; AROMATASE; ESTRADIOL; ESTROGEN RECEPTOR; FOLLITROPIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LUTEINIZING HORMONE; OSTEOCALCIN; PRASTERONE; PROLACTIN; SOMATOMEDIN C; STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 0033061324     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1400111     Document Type: Review
Times cited : (124)

References (155)
  • 1
    • 0001872893 scopus 로고
    • Sex determination and differentiation
    • ch 1, Eds E Knobil & JD Neill. New York: Raven Press
    • George FW & Wilson JD. Sex determination and differentiation. In The Physiology of Reproduction, ch 1, pp 3-26. Eds E Knobil & JD Neill. New York: Raven Press, 1988.
    • (1988) The Physiology of Reproduction , pp. 3-26
    • George, F.W.1    Wilson, J.D.2
  • 8
    • 0026785124 scopus 로고
    • Genetic studies to characterize the origin of the mutation in placental aromatase deficiency
    • Harada N, Ogawa H, Shozu M & Yamada K. Genetic studies to characterize the origin of the mutation in placental aromatase deficiency. American Journal of Human Genetics 1992 51 666-672.
    • (1992) American Journal of Human Genetics , vol.51 , pp. 666-672
    • Harada, N.1    Ogawa, H.2    Shozu, M.3    Yamada, K.4
  • 10
    • 0028298216 scopus 로고
    • A syndrome of female pseudohermaphroditism, hypergonadotropic hypogonadism, and multicystic ovaries associated with missense mutations in the gene encoding aromatase (P450arom)
    • Conte FA, Grumbach MM, Ito Y, Fisher CR & Simpson ER. A syndrome of female pseudohermaphroditism, hypergonadotropic hypogonadism, and multicystic ovaries associated with missense mutations in the gene encoding aromatase (P450arom). Journal of Clinical Endocrinology and Metabolism 1994 78 1287-1292.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 1287-1292
    • Conte, F.A.1    Grumbach, M.M.2    Ito, Y.3    Fisher, C.R.4    Simpson, E.R.5
  • 13
    • 0028625491 scopus 로고
    • Insights from the study of animals lacking functional estrogen receptor
    • Korach KS. Insights from the study of animals lacking functional estrogen receptor. Science 1994 266 1524-1527.
    • (1994) Science , vol.266 , pp. 1524-1527
    • Korach, K.S.1
  • 15
    • 0001878449 scopus 로고    scopus 로고
    • Female pseudohermaphroditism resulting from aromatase (P450arom) deficiency associated with a novel mutation (R457X) in the CYP19 gene
    • Portrat-Doyen S, Forest MG, Nicolino M, Morel Y & Chatelain PC. Female pseudohermaphroditism resulting from aromatase (P450arom) deficiency associated with a novel mutation (R457X) in the CYP19 gene. Hormone Research 1996 46 (Suppl 2) 14.
    • (1996) Hormone Research , vol.46 , Issue.2 SUPPL. , pp. 14
    • Portrat-Doyen, S.1    Forest, M.G.2    Nicolino, M.3    Morel, Y.4    Chatelain, P.C.5
  • 16
    • 0031154045 scopus 로고    scopus 로고
    • Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: Impact of estrogens on hypergonadotropic hypogonadism. multicystic ovaries, and bone densitometry in childhood
    • Mullis PE, Yoshimura N, Kuhlmann B, Lippuner K, Jaeger P & Harada H. Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: impact of estrogens on hypergonadotropic hypogonadism. multicystic ovaries, and bone densitometry in childhood. Journal of Clinical Endocrinology and Metabolism 1997 82 1739-1745.
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 1739-1745
    • Mullis, P.E.1    Yoshimura, N.2    Kuhlmann, B.3    Lippuner, K.4    Jaeger, P.5    Harada, H.6
  • 19
    • 0028919090 scopus 로고
    • Estrogen receptors in human nontarget tissues: Biological and clinical implications
    • Ciocca DR & Vargas Roig LM. Estrogen receptors in human nontarget tissues: biological and clinical implications. Endocrine Reviews 1995 16 35-62.
    • (1995) Endocrine Reviews , vol.16 , pp. 35-62
    • Ciocca, D.R.1    Vargas Roig, L.M.2
  • 22
    • 0030031782 scopus 로고    scopus 로고
    • Estrogen receptors: Bioactivities and interactions with cell signaling pathways
    • Katzenellenbogen BS. Estrogen receptors: bioactivities and interactions with cell signaling pathways. Biology of Reproduction 1996 54 287-293.
    • (1996) Biology of Reproduction , vol.54 , pp. 287-293
    • Katzenellenbogen, B.S.1
  • 23
    • 0029807308 scopus 로고    scopus 로고
    • Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding
    • Ekena KE, Weis KE, Katzenellenbogen JA & Katzenellenbogen BS. Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding. Journal of Biological Chemistry 1996 271 20053-20059.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 20053-20059
    • Ekena, K.E.1    Weis, K.E.2    Katzenellenbogen, J.A.3    Katzenellenbogen, B.S.4
  • 24
    • 0030944524 scopus 로고    scopus 로고
    • Estrogen receptor residues required for stereospecific ligand recognition and activation
    • Bocchinfuso WP & Korach KS. Estrogen receptor residues required for stereospecific ligand recognition and activation. Molecular Endocrinology 1997 11 587-594.
    • (1997) Molecular Endocrinology , vol.11 , pp. 587-594
    • Bocchinfuso, W.P.1    Korach, K.S.2
  • 26
    • 0029985147 scopus 로고    scopus 로고
    • Physiological coupling of growth factor and steroid receptor signaling pathway: Estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor
    • Curtis SW, Washburn T, Sewall C, DiAugustine R, Lindzey J, Couse JF et al Physiological coupling of growth factor and steroid receptor signaling pathway: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. Proceedings of the National Academy of Sciences of the USA 1996 93 12626-12630.
    • (1996) Proceedings of the National Academy of Sciences of the USA , vol.93 , pp. 12626-12630
    • Curtis, S.W.1    Washburn, T.2    Sewall, C.3    DiAugustine, R.4    Lindzey, J.5    Couse, J.F.6
  • 28
    • 0030593681 scopus 로고    scopus 로고
    • ER-β: Identification and characterization of a novel human estrogen receptor
    • Mosselman S, Polman J & Dijkema R. ER-β: identification and characterization of a novel human estrogen receptor FEBS Letters 1996 392 49-53.
    • (1996) FEBS Letters , vol.392 , pp. 49-53
    • Mosselman, S.1    Polman, J.2    Dijkema, R.3
  • 29
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β
    • Kuiper GGJM, Carlsson B, Grandien J, Enmark E, Haggblad J, Nilsson S et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 1997 138 863-870.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, J.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6
  • 32
    • 0024853552 scopus 로고
    • Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis
    • Means GD, Mahendroo M, Corbin CJ, Mathis JM, Powell FE, Mendelson CR et al. Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. Journal of Biological Chemistry 1989 264 19385-19391.
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 19385-19391
    • Means, G.D.1    Mahendroo, M.2    Corbin, C.J.3    Mathis, J.M.4    Powell, F.E.5    Mendelson, C.R.6
  • 35
    • 0018547573 scopus 로고
    • The production of progesterone, androgens, and estrogens by granulosa cells, theca tissue and stromal tissue from human ovaries in vitro
    • McNatty KP, Makris A & DeGrazia C. The production of progesterone, androgens, and estrogens by granulosa cells, theca tissue and stromal tissue from human ovaries in vitro. Journal of Clinical Endocrinology and Metabolism 1979 49 687-699.
    • (1979) Journal of Clinical Endocrinology and Metabolism , vol.49 , pp. 687-699
    • McNatty, K.P.1    Makris, A.2    DeGrazia, C.3
  • 36
    • 0027141308 scopus 로고
    • Use of tissue specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumours, as well as in normal fetal and adult gonads
    • Bulun SE, Rosenthal IM, Brodie AMH, Inkster SE, Zeller WP, DiGeorge AM et al. Use of tissue specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumours, as well as in normal fetal and adult gonads. Journal of Clinical Endocrinology and Metabolism 1993 77 1616-1621.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.77 , pp. 1616-1621
    • Bulun, S.E.1    Rosenthal, I.M.2    Brodie, A.M.H.3    Inkster, S.E.4    Zeller, W.P.5    DiGeorge, A.M.6
  • 37
    • 0025939110 scopus 로고
    • Expression of aromatase P-450 in premenopausal and postmenopausal human ovaries: An immunocytochemical study
    • Inkster SE & Brodie AMH. Expression of aromatase P-450 in premenopausal and postmenopausal human ovaries: an immunocytochemical study. Journal of Clinical Endocrinology and Metabolism 1991 73 717-726.
    • (1991) Journal of Clinical Endocrinology and Metabolism , vol.73 , pp. 717-726
    • Inkster, S.E.1    Brodie, A.M.H.2
  • 38
    • 0026396006 scopus 로고
    • Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues
    • Means GD, Kilgore MW, Mahendroo MS, Mendelson CR & Simpson ER. Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues. Molecular Endocrinology 1991 5 2005-2013.
    • (1991) Molecular Endocrinology , vol.5 , pp. 2005-2013
    • Means, G.D.1    Kilgore, M.W.2    Mahendroo, M.S.3    Mendelson, C.R.4    Simpson, E.R.5
  • 39
    • 0023180688 scopus 로고
    • Purification and characterization of human placental aromatase cytochrome P-450
    • Kellis JT & Vickery LE. Purification and characterization of human placental aromatase cytochrome P-450. Journal of Biological Chemistry 1987 262 4413-4420.
    • (1987) Journal of Biological Chemistry , vol.262 , pp. 4413-4420
    • Kellis, J.T.1    Vickery, L.E.2
  • 41
    • 0024828449 scopus 로고
    • Immunocytochemical studies of aromatase in early and full-term human placental tissue: Comparison with biochemical assays
    • Inkster SE & Brodie AMH. Immunocytochemical studies of aromatase in early and full-term human placental tissue: comparison with biochemical assays. Biology of Reproduction 1989 41 889-898.
    • (1989) Biology of Reproduction , vol.41 , pp. 889-898
    • Inkster, S.E.1    Brodie, A.M.H.2
  • 43
    • 0015318131 scopus 로고
    • Estradiol and testosterone secretion by human, simian and canine testes, in male with hypogonadism and in male pseudohermaphrodite with the feminizing testes syndrome
    • Kelch RP, Jenner MR, Weinstein R, Kaplan SL & Grumbach MM. Estradiol and testosterone secretion by human, simian and canine testes, in male with hypogonadism and in male pseudohermaphrodite with the feminizing testes syndrome. Journal of Clinical Investigation 1972 51 824-830.
    • (1972) Journal of Clinical Investigation , vol.51 , pp. 824-830
    • Kelch, R.P.1    Jenner, M.R.2    Weinstein, R.3    Kaplan, S.L.4    Grumbach, M.M.5
  • 45
    • 0021924875 scopus 로고
    • Cellular localization of rat testicular aromatase activity during development
    • Tsai-Morris C-H, Aquilano DR & Dufau ML. Cellular localization of rat testicular aromatase activity during development. Endocrinology 1985 116 38-46.
    • (1985) Endocrinology , vol.116 , pp. 38-46
    • Tsai-Morris, C.-H.1    Aquilano, D.R.2    Dufau, M.L.3
  • 51
    • 0029879369 scopus 로고    scopus 로고
    • Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis
    • Janulis L, Hess RA, Bunick D, Nitta H, Janssen S, Asawa Y et al. Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis. Journal of Andrology 1996 17 111-116.
    • (1996) Journal of Andrology , vol.17 , pp. 111-116
    • Janulis, L.1    Hess, R.A.2    Bunick, D.3    Nitta, H.4    Janssen, S.5    Asawa, Y.6
  • 56
    • 0020202030 scopus 로고
    • Regulation of aromatase activity of stromal cells derived from human adipose tissue
    • Mendelson CR, Cleland WH, Smith ME & Simpson ER. Regulation of aromatase activity of stromal cells derived from human adipose tissue Endocrinology 1982 111 1077-1085.
    • (1982) Endocrinology , vol.111 , pp. 1077-1085
    • Mendelson, C.R.1    Cleland, W.H.2    Smith, M.E.3    Simpson, E.R.4
  • 58
    • 0025914639 scopus 로고
    • Tissue-specific expression of human P450 arom: The promoter responsible for expression in adipose is different from that utilized in placenta
    • Mahendroo MS, Means GD, Mendelson CR & Simpson ER. Tissue-specific expression of human P450 arom: the promoter responsible for expression in adipose is different from that utilized in placenta. Journal of Biological Chemistry 1991 266 11276-11281.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 11276-11281
    • Mahendroo, M.S.1    Means, G.D.2    Mendelson, C.R.3    Simpson, E.R.4
  • 59
    • 0027261356 scopus 로고
    • Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue
    • Mahendroo MS, Mendelson CR & Simpson ER. Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue. Journal of Biological Chemistry 1993 268 19463-19470.
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 19463-19470
    • Mahendroo, M.S.1    Mendelson, C.R.2    Simpson, E.R.3
  • 60
    • 0028919673 scopus 로고
    • Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes
    • Zhao Y, Mendelson CR & Simpson ER. Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes. Molecular Endocrinology 1995 9 340-349.
    • (1995) Molecular Endocrinology , vol.9 , pp. 340-349
    • Zhao, Y.1    Mendelson, C.R.2    Simpson, E.R.3
  • 61
    • 0029002074 scopus 로고
    • Aromatase P450 gene expression in human adipose tissue: Role of a Jak/STAT pathway in regulation of the adipose-specific promoter
    • Zhao Y, Nichols JE, Bulun SE, Mendelson CR & Simpson ER. Aromatase P450 gene expression in human adipose tissue: role of a Jak/STAT pathway in regulation of the adipose-specific promoter. Journal of Biological Chemistry 1995 270 16449-16457.
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 16449-16457
    • Zhao, Y.1    Nichols, J.E.2    Bulun, S.E.3    Mendelson, C.R.4    Simpson, E.R.5
  • 63
    • 0005438378 scopus 로고
    • Secretion and metabolism of adrenal androgens to estrogens
    • Eds VHT James, M Serio, G Giusti & L Martini, New York: Academic Press
    • Siiteri PK & Seron-Ferre M. Secretion and metabolism of adrenal androgens to estrogens. In The Endocrine Function of the Human Adrenal Cortex, pp 251-264. Eds VHT James, M Serio, G Giusti & L Martini, New York: Academic Press, 1978.
    • (1978) The Endocrine Function of the Human Adrenal Cortex , pp. 251-264
    • Siiteri, P.K.1    Seron-Ferre, M.2
  • 64
    • 0022348964 scopus 로고
    • Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system
    • Roselli CE, Hurton LE & Resko JA. Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system. Endocrinology 1985 117 2471-2477.
    • (1985) Endocrinology , vol.117 , pp. 2471-2477
    • Roselli, C.E.1    Hurton, L.E.2    Resko, J.A.3
  • 65
    • 0028069877 scopus 로고
    • Androgens influence sexual differentiation of embryonic mouse hypothalamic aromatase neurons in vitro
    • Beyer C, Green SJ & Hutchison JB. Androgens influence sexual differentiation of embryonic mouse hypothalamic aromatase neurons in vitro. Endocrinology 1994 135 1220-1226.
    • (1994) Endocrinology , vol.135 , pp. 1220-1226
    • Beyer, C.1    Green, S.J.2    Hutchison, J.B.3
  • 66
    • 0028025188 scopus 로고
    • Pre- And postnatal ontogeny of aromatase cytochrome P450 messenger ribonucleic acid expression in the male rat brain studied by in situ hybridization
    • Lauber ME & Lichtensteiger W. Pre- and postnatal ontogeny of aromatase cytochrome P450 messenger ribonucleic acid expression in the male rat brain studied by in situ hybridization. Endocrinology 1994 135 1661-1666.
    • (1994) Endocrinology , vol.135 , pp. 1661-1666
    • Lauber, M.E.1    Lichtensteiger, W.2
  • 67
    • 0030174660 scopus 로고    scopus 로고
    • A review of brain aromatase cytochrome P450
    • Lephart ED. A review of brain aromatase cytochrome P450. Brain Research Reviews 1996 22 1-26.
    • (1996) Brain Research Reviews , vol.22 , pp. 1-26
    • Lephart, E.D.1
  • 70
    • 0024385223 scopus 로고
    • Aromatase activity in microsomal preparations of human genital skin fibroblasts: Influence of glucocorticoids
    • Berkovitz GD, Bisat T & Carter KM. Aromatase activity in microsomal preparations of human genital skin fibroblasts: influence of glucocorticoids. Journal of Steroid Biochemistry 1989 33 341-347.
    • (1989) Journal of Steroid Biochemistry , vol.33 , pp. 341-347
    • Berkovitz, G.D.1    Bisat, T.2    Carter, K.M.3
  • 71
    • 0027099861 scopus 로고
    • A unique aromatase (P450 arom) mRNA formed by alternative use of tissue specific exons I in human skin fibroblasts
    • Harada N. A unique aromatase (P450 arom) mRNA formed by alternative use of tissue specific exons I in human skin fibroblasts. Biochemical and Biophysical Research Communications 1992 189 1001-1007.
    • (1992) Biochemical and Biophysical Research Communications , vol.189 , pp. 1001-1007
    • Harada, N.1
  • 72
    • 0026507049 scopus 로고
    • Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction (PCR) amplification
    • Price T, Aitken J & Simpson ER. Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction (PCR) amplification. Journal of Clinical Endocrinology and Metabolism 1992 74 879-883.
    • (1992) Journal of Clinical Endocrinology and Metabolism , vol.74 , pp. 879-883
    • Price, T.1    Aitken, J.2    Simpson, E.R.3
  • 73
    • 0027362649 scopus 로고
    • Tissue-specific expression of the human aromatase cytochrome P450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis
    • Harada N, Utsume T & Takagi Y. Tissue-specific expression of the human aromatase cytochrome P450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proceedings of the National Academy of Sciences of the USA 1993 90 11312-11316.
    • (1993) Proceedings of the National Academy of Sciences of the USA , vol.90 , pp. 11312-11316
    • Harada, N.1    Utsume, T.2    Takagi, Y.3
  • 77
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen within the breast
    • Miller WR & O'Neill J. The importance of local synthesis of estrogen within the breast. Steroids 1987 50 537-548.
    • (1987) Steroids , vol.50 , pp. 537-548
    • Miller, W.R.1    O'Neill, J.2
  • 78
    • 0028319003 scopus 로고
    • Regulation of the CYP19 (P450 arom) gene expression in breast adipose tissue and breast cancer
    • Bulun SE & Simpson ER. Regulation of the CYP19 (P450 arom) gene expression in breast adipose tissue and breast cancer. Trends in Endocrinology and Metabolism 1994 5 113-120.
    • (1994) Trends in Endocrinology and Metabolism , vol.5 , pp. 113-120
    • Bulun, S.E.1    Simpson, E.R.2
  • 79
    • 0028302746 scopus 로고
    • Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders
    • Sasano H, Nagura H, Harada N, Goukon Y & Kimura M. Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Human Pathology 1994 25 530-535.
    • (1994) Human Pathology , vol.25 , pp. 530-535
    • Sasano, H.1    Nagura, H.2    Harada, N.3    Goukon, Y.4    Kimura, M.5
  • 82
    • 0029941512 scopus 로고    scopus 로고
    • Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers
    • Lu Q, Nakmura J, Savinov A, Yue W, Weisz J, Dabbs DJ et al. Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers. Endocrinology 1996 137 3061-3068.
    • (1996) Endocrinology , vol.137 , pp. 3061-3068
    • Lu, Q.1    Nakmura, J.2    Savinov, A.3    Yue, W.4    Weisz, J.5    Dabbs, D.J.6
  • 86
    • 0029984402 scopus 로고    scopus 로고
    • Identification and characterization of transcriptional regulatory elements of the human aromatase cytochrome P450 gene (CYP19)
    • Toda K, Nomoto S & Shizuta Y. Identification and characterization of transcriptional regulatory elements of the human aromatase cytochrome P450 gene (CYP19). Journal of Steroid Biochemistry and Molecular Biology 1996 56 151-159.
    • (1996) Journal of Steroid Biochemistry and Molecular Biology , vol.56 , pp. 151-159
    • Toda, K.1    Nomoto, S.2    Shizuta, Y.3
  • 88
    • 0031792594 scopus 로고    scopus 로고
    • Multiple splicing events involved in regulation of human aromatase expression by a novel promoter, I.6
    • Shozu M, Zhao Y, Bulun SE & Simpson E. Multiple splicing events involved in regulation of human aromatase expression by a novel promoter, I.6. Endocrinology 1998 139 1610-1617.
    • (1998) Endocrinology , vol.139 , pp. 1610-1617
    • Shozu, M.1    Zhao, Y.2    Bulun, S.E.3    Simpson, E.4
  • 89
    • 0031007224 scopus 로고    scopus 로고
    • Developmental and physiological effects of estrogen receptor gene disruption in mice
    • Lindzey J & Korach KS. Developmental and physiological effects of estrogen receptor gene disruption in mice. Trends in Endocrinology and Metabolism 1997 8 137-145.
    • (1997) Trends in Endocrinology and Metabolism , vol.8 , pp. 137-145
    • Lindzey, J.1    Korach, K.S.2
  • 90
    • 0028866648 scopus 로고
    • Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene
    • Couse JF, Curtis SW, Washburn TF, Lindzey J, Golding TS, Lubahn DB et al. Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. Molecular Endocrinology 1995 9 1441-1454.
    • (1995) Molecular Endocrinology , vol.9 , pp. 1441-1454
    • Couse, J.F.1    Curtis, S.W.2    Washburn, T.F.3    Lindzey, J.4    Golding, T.S.5    Lubahn, D.B.6
  • 91
    • 0029969771 scopus 로고    scopus 로고
    • Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility
    • Eddy EM, Washburn TF, Bunch DO, Goulding EH, Gladen BC, Lubahn DB et al. Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 1996 137 4796-4805.
    • (1996) Endocrinology , vol.137 , pp. 4796-4805
    • Eddy, E.M.1    Washburn, T.F.2    Bunch, D.O.3    Goulding, E.H.4    Gladen, B.C.5    Lubahn, D.B.6
  • 94
    • 0031171415 scopus 로고    scopus 로고
    • Estrogen receptor function as revealed by knockout studies: Neuroendocrine and behavioral aspects
    • Rissman EF, Wersinger SR, Taylor JA & Lubahn DB. Estrogen receptor function as revealed by knockout studies: neuroendocrine and behavioral aspects. Hormones and Behaviour 1997 31 232-243.
    • (1997) Hormones and Behaviour , vol.31 , pp. 232-243
    • Rissman, E.F.1    Wersinger, S.R.2    Taylor, J.A.3    Lubahn, D.B.4
  • 95
  • 96
    • 0027420909 scopus 로고
    • Estrogen receptor and progesterone receptor genes are expressed differentially in mouse embryos during preimplantation development
    • Hou Q & Gorski J. Estrogen receptor and progesterone receptor genes are expressed differentially in mouse embryos during preimplantation development. Proceedings of the National Academy of Sciences of the USA 1993 90 9460-9464.
    • (1993) Proceedings of the National Academy of Sciences of the USA , vol.90 , pp. 9460-9464
    • Hou, Q.1    Gorski, J.2
  • 98
    • 0030815423 scopus 로고    scopus 로고
    • Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man
    • Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane JP et al. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation 1997 96 3774-3777.
    • (1997) Circulation , vol.96 , pp. 3774-3777
    • Sudhir, K.1    Chou, T.M.2    Chatterjee, K.3    Smith, E.P.4    Williams, T.C.5    Kane, J.P.6
  • 99
    • 0032462138 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones in reproductive tissues
    • Revelli A, Massobrio M & Tesarik J. Nongenomic actions of steroid hormones in reproductive tissues. Endocrine Reviews 1998 19 3-17.
    • (1998) Endocrine Reviews , vol.19 , pp. 3-17
    • Revelli, A.1    Massobrio, M.2    Tesarik, J.3
  • 100
    • 0027232797 scopus 로고
    • Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?
    • Sharpe RM & Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 1993 341 1392-1395.
    • (1993) Lancet , vol.341 , pp. 1392-1395
    • Sharpe, R.M.1    Skakkebaek, N.E.2
  • 103
    • 0031734593 scopus 로고    scopus 로고
    • Identification of multiple CYP19 genes encoding different cytochrome P450 aromatase isozymes in brain and ovary
    • Tchoudakova A & Callard GV. Identification of multiple CYP19 genes encoding different cytochrome P450 aromatase isozymes in brain and ovary. Endocrinology 1998 139 2179-2189.
    • (1998) Endocrinology , vol.139 , pp. 2179-2189
    • Tchoudakova, A.1    Callard, G.V.2
  • 105
    • 0026592208 scopus 로고
    • Functional domains of aromatase cytochrome P450 inferred from comparative analyses of amino acid sequences and substantiated by site-directed mutagenesis experiments
    • Chen S & Zhou D. Functional domains of aromatase cytochrome P450 inferred from comparative analyses of amino acid sequences and substantiated by site-directed mutagenesis experiments. Journal of Biological Chemistry 1992 267 22587-22594.
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 22587-22594
    • Chen, S.1    Zhou, D.2
  • 107
    • 0028334187 scopus 로고
    • Correlation between low levels of estrogen receptors and estrogen responsiveness in two rat osteoblast-like cell lines
    • Davis VL, Couse JF, Gray TK & Korach KS. Correlation between low levels of estrogen receptors and estrogen responsiveness in two rat osteoblast-like cell lines. Journal of Bone and Mineral Research 1994 9 983-991.
    • (1994) Journal of Bone and Mineral Research , vol.9 , pp. 983-991
    • Davis, V.L.1    Couse, J.F.2    Gray, T.K.3    Korach, K.S.4
  • 110
    • 0028693735 scopus 로고
    • Adolescence in evolutionary perspective
    • Bogin B. Adolescence in evolutionary perspective. Acta Paediatrica (Suppl) 1994 406 29-35.
    • (1994) Acta Paediatrica , vol.406 , Issue.SUPPL. , pp. 29-35
    • Bogin, B.1
  • 113
    • 0025177910 scopus 로고
    • The endocrinology of the pubertal growth spurt
    • Pescovitz OH. The endocrinology of the pubertal growth spurt. Acta Paediatrica Scandinavica 1990 367 119-125.
    • (1990) Acta Paediatrica Scandinavica , vol.367 , pp. 119-125
    • Pescovitz, O.H.1
  • 114
    • 0026921780 scopus 로고
    • Pubertal growth in genetic disorders of sex hormone action and secretion
    • Ritzen EM. Pubertal growth in genetic disorders of sex hormone action and secretion. Acta Paediatrica Scandinavica 1992 383 22-25.
    • (1992) Acta Paediatrica Scandinavica , vol.383 , pp. 22-25
    • Ritzen, E.M.1
  • 116
    • 0027417528 scopus 로고
    • Androgen-stimulated pubertal growth: The effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty
    • Keenan BS, Richards GE, Ponder SW, Dallas JS, Nagamani M & Smith ER. Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. Journal of Clinical Endocrinology and Metabolism 1993 76 996-1001.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 996-1001
    • Keenan, B.S.1    Richards, G.E.2    Ponder, S.W.3    Dallas, J.S.4    Nagamani, M.5    Smith, E.R.6
  • 117
    • 0028025054 scopus 로고
    • Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: Evidence for a stimulatory role of endogenous estrogens during male adolescence
    • Metzger DL & Kerrigan JR. Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: evidence for a stimulatory role of endogenous estrogens during male adolescence. Journal of Clinical Endocrinology and Metabolism 1994 79 513-518.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.79 , pp. 513-518
    • Metzger, D.L.1    Kerrigan, J.R.2
  • 118
    • 0028905776 scopus 로고
    • Combination treatment with growth hormone and gonadotropin-releasing hormone analogs in short normal girls
    • Saggese G, Cesaretti G, Barsanti S & Rossi A. Combination treatment with growth hormone and gonadotropin-releasing hormone analogs in short normal girls. Journal of Pediatrics 1995 126 468-473.
    • (1995) Journal of Pediatrics , vol.126 , pp. 468-473
    • Saggese, G.1    Cesaretti, G.2    Barsanti, S.3    Rossi, A.4
  • 119
    • 0029060778 scopus 로고
    • The role of estrogen in pubertal skeletal physiology: Epiphyseal maturation and mineralization of the skeleton
    • Frank GR. The role of estrogen in pubertal skeletal physiology: epiphyseal maturation and mineralization of the skeleton. Acta Paediatrica 1995 84 627-630.
    • (1995) Acta Paediatrica , vol.84 , pp. 627-630
    • Frank, G.R.1
  • 120
    • 0030255994 scopus 로고    scopus 로고
    • Oestrogen receptor deficiency: Consequences for growth
    • Smith EP & Korach KS. Oestrogen receptor deficiency: consequences for growth. Acta Paediatrica (Suppl) 1996 417 39-43.
    • (1996) Acta Paediatrica , vol.417 , Issue.SUPPL. , pp. 39-43
    • Smith, E.P.1    Korach, K.S.2
  • 123
    • 0022529328 scopus 로고
    • Pubertal growth in patients with androgen insensitivity: Indirect evidence for the importance of estrogens in pubertal growth of girls
    • Zachmann M, Prader A, Sabel EH, Crigler JF, Ritzen EM, Atares M et al. Pubertal growth in patients with androgen insensitivity: indirect evidence for the importance of estrogens in pubertal growth of girls. Journal of Pediatrics 1986 108 694-697.
    • (1986) Journal of Pediatrics , vol.108 , pp. 694-697
    • Zachmann, M.1    Prader, A.2    Sabel, E.H.3    Crigler, J.F.4    Ritzen, E.M.5    Atares, M.6
  • 124
    • 0026081588 scopus 로고
    • 17α-hydroxylase/ 17.20-lyase deficiency: From clinical Investigation to molecular definition
    • Yanase T, Simpson ER & Waterman MR. 17α-hydroxylase/ 17.20-lyase deficiency: from clinical Investigation to molecular definition. Endocrine Reviews 1991 12 91-108.
    • (1991) Endocrine Reviews , vol.12 , pp. 91-108
    • Yanase, T.1    Simpson, E.R.2    Waterman, M.R.3
  • 128
    • 0027372340 scopus 로고
    • A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
    • Shenker A, Laue L, Kosugi S, Merendino JJ Jr, Minegishi T & Cutler GB Jr. A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature 1993 365 652-654.
    • (1993) Nature , vol.365 , pp. 652-654
    • Shenker, A.1    Laue, L.2    Kosugi, S.3    Merendino J.J., Jr.4    Minegishi, T.5    Cutler G.B., Jr.6
  • 129
    • 0027956207 scopus 로고
    • Rapid GDP release from Gsα in patients with gain and loss of endocrine function
    • Iiri T, Herzmark P, Nakamoto JM, Van Dop C & Bourne HR. Rapid GDP release from Gsα in patients with gain and loss of endocrine function. Nature 1994 371 164-168.
    • (1994) Nature , vol.371 , pp. 164-168
    • Iiri, T.1    Herzmark, P.2    Nakamoto, J.M.3    Van Dop, C.4    Bourne, H.R.5
  • 131
    • 0027462430 scopus 로고
    • The effect of oxandrolone on the growth hormone axes of boys with constitutional delay of growth and puberty
    • Malhotra A, Poon E, Tse WY, Pringle PJ, Hindmarsh PC & Brook CGD. The effect of oxandrolone on the growth hormone axes of boys with constitutional delay of growth and puberty. Clinical Endocrinology 1993 38 393-398.
    • (1993) Clinical Endocrinology , vol.38 , pp. 393-398
    • Malhotra, A.1    Poon, E.2    Tse, W.Y.3    Pringle, P.J.4    Hindmarsh, P.C.5    Brook, C.G.D.6
  • 132
    • 0027417528 scopus 로고
    • Androgen-stimulated pubertal growth: The effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty
    • Keenan BS, Richards GE, Ponder SW, Dallas JS, Nagamani M & Smith ER. Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. Journal of Clinical Endocrinology and Metabolism 1993 76 996-1001.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , pp. 996-1001
    • Keenan, B.S.1    Richards, G.E.2    Ponder, S.W.3    Dallas, J.S.4    Nagamani, M.5    Smith, E.R.6
  • 134
    • 0028157059 scopus 로고
    • The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol
    • Bagatell CJ, Dahl KD & Bremner WJ. The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol. Journal of Andrology 1994 15 15-21.
    • (1994) Journal of Andrology , vol.15 , pp. 15-21
    • Bagatell, C.J.1    Dahl, K.D.2    Bremner, W.J.3
  • 135
    • 0031406115 scopus 로고    scopus 로고
    • Estrogen receptor (α and β) expression in the excurrent ducts of the adult male rat reproductive tract
    • Hess RA, Gist DH, Bunick D, Lubahn DB, Farrell A, Bahr J et al. Estrogen receptor (α and β) expression in the excurrent ducts of the adult male rat reproductive tract. Journal of Andrology 1997 18 602-611.
    • (1997) Journal of Andrology , vol.18 , pp. 602-611
    • Hess, R.A.1    Gist, D.H.2    Bunick, D.3    Lubahn, D.B.4    Farrell, A.5    Bahr, J.6
  • 136
    • 0031468567 scopus 로고    scopus 로고
    • Do males rely on female hormones?
    • Sharpe RM. Do males rely on female hormones? Nature 1997 390 447-448.
    • (1997) Nature , vol.390 , pp. 447-448
    • Sharpe, R.M.1
  • 137
    • 0030975888 scopus 로고    scopus 로고
    • Immunolocalisation of oestrogen receptor-α within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood
    • Fisher JS, Millar MR, Majdic G, Saunders PTK, Fraser HM & Sharpe RM. Immunolocalisation of oestrogen receptor-α within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood. Journal of Endocrinology 1997 153 485-495.
    • (1997) Journal of Endocrinology , vol.153 , pp. 485-495
    • Fisher, J.S.1    Millar, M.R.2    Majdic, G.3    Saunders, P.T.K.4    Fraser, H.M.5    Sharpe, R.M.6
  • 138
    • 0030824020 scopus 로고    scopus 로고
    • Expression of oestrogen receptor beta (ERβ) in multiple rat tissues visualised by immunohistochemistry
    • Saunders PTK, Maguire SM, Gaughan J & Millar RM. Expression of oestrogen receptor beta (ERβ) in multiple rat tissues visualised by immunohistochemistry. Journal of Endocrinology 1997 154 R13-R16.
    • (1997) Journal of Endocrinology , vol.154
    • Saunders, P.T.K.1    Maguire, S.M.2    Gaughan, J.3    Millar, R.M.4
  • 142
    • 0027270229 scopus 로고
    • Expression of estrogen receptor mRNA in tumorous and non-tumorous liver tissue as detected by in situ hybridization
    • Pacchioni D, Papotti M, Andorno E, Bonino F, Mondardini A, Olivieri F et al. Expression of estrogen receptor mRNA in tumorous and non-tumorous liver tissue as detected by in situ hybridization. Journal of Surgical Oncology 1993 3 (Suppl) 14-17.
    • (1993) Journal of Surgical Oncology , vol.3 , Issue.SUPPL. , pp. 14-17
    • Pacchioni, D.1    Papotti, M.2    Andorno, E.3    Bonino, F.4    Mondardini, A.5    Olivieri, F.6
  • 144
    • 0030963363 scopus 로고    scopus 로고
    • Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene
    • Sudhir K, Chou TM, Messina LM, Hutchinson SJ, Korach KS, Chatterjee K et al. Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene. Lancet 1997 349 1146-1147.
    • (1997) Lancet , vol.349 , pp. 1146-1147
    • Sudhir, K.1    Chou, T.M.2    Messina, L.M.3    Hutchinson, S.J.4    Korach, K.S.5    Chatterjee, K.6
  • 145
    • 0030952581 scopus 로고    scopus 로고
    • Suppression of endogenous testosterone in young men increases serum levels of high density lipoprotein subclass lipoprotein A-I and lipoprotein (a)
    • Eckardstein A, Kliesch S, Nieschlag E, Chirazi A, Assmann G & Behre HM. Suppression of endogenous testosterone in young men increases serum levels of high density lipoprotein subclass lipoprotein A-I and lipoprotein (a). Journal of Clinical Endocrinology and Metabolism 1997 82 3367-3372.
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 3367-3372
    • Eckardstein, A.1    Kliesch, S.2    Nieschlag, E.3    Chirazi, A.4    Assmann, G.5    Behre, H.M.6
  • 146
    • 0030047305 scopus 로고    scopus 로고
    • Randomised comparison of oestrogen versus oestrogen plus progestogen hormone replacement therapy in women with hysterectomy
    • Medical Research Council's General Practice Research Framework. Randomised comparison of oestrogen versus oestrogen plus progestogen hormone replacement therapy in women with hysterectomy. British Medical Journal 1996 312 473-478.
    • (1996) British Medical Journal , vol.312 , pp. 473-478
  • 147
    • 0025014653 scopus 로고
    • High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: The follow-up study of the lipid research clinics prevalence study
    • Jacobs DR, Mebane IL, Bangdwala SI, Criqui MH & Tyroler HA. High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: the follow-up study of the lipid research clinics prevalence study. American Journal of Epidemiology 1990 131 32-47.
    • (1990) American Journal of Epidemiology , vol.131 , pp. 32-47
    • Jacobs, D.R.1    Mebane, I.L.2    Bangdwala, S.I.3    Criqui, M.H.4    Tyroler, H.A.5
  • 152
    • 0029665118 scopus 로고    scopus 로고
    • Aromatase deficiency in women and men: Would you have predicted the phenotypes?
    • Bulun SE. Aromatase deficiency in women and men: would you have predicted the phenotypes? Journal of Clinical Endocrinology and Metabolism 1996 81 867-871.
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , pp. 867-871
    • Bulun, S.E.1
  • 153
    • 0030873034 scopus 로고    scopus 로고
    • Importance of estrogens in human males' fertility and bone pathophysiology
    • Asteria C. Importance of estrogens in human males' fertility and bone pathophysiology. European Journal of Endocrinology 1997 137 120-121.
    • (1997) European Journal of Endocrinology , vol.137 , pp. 120-121
    • Asteria, C.1
  • 154
    • 0026794199 scopus 로고
    • Differences between male and female brains - Developmental mechanisms and implications
    • Pilgrim C & Reisert J. Differences between male and female brains - developmental mechanisms and implications. Hormone and Metabolic Research 1992 24 151-159.
    • (1992) Hormone and Metabolic Research , vol.24 , pp. 151-159
    • Pilgrim, C.1    Reisert, J.2
  • 155
    • 0026308375 scopus 로고
    • Hormonal control of behaviour: Steroid action in the brain
    • Hutchinson JB. Hormonal control of behaviour: steroid action in the brain. Current Opinions in Neurobiology 1991 1 562-570.
    • (1991) Current Opinions in Neurobiology , vol.1 , pp. 562-570
    • Hutchinson, J.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.