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Volumn 137, Issue 7, 1996, Pages 3061-3068

Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; ESTROGEN; MESSENGER RNA; TESTOSTERONE;

EID: 0029941512     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.7.8770932     Document Type: Article
Times cited : (174)

References (48)
  • 2
    • 0015984830 scopus 로고
    • Plasma precursors of estrogen. II Correlation of the extend of conversion of plasma androstenedione to estrone with age
    • Hemsell DL, Gordon J, Brenner PF, Siiteri PK 1974 Plasma precursors of estrogen. II Correlation of the extend of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab 38:476-479
    • (1974) J Clin Endocrinol Metab , vol.38 , pp. 476-479
    • Hemsell, D.L.1    Gordon, J.2    Brenner, P.F.3    Siiteri, P.K.4
  • 3
    • 0017131714 scopus 로고
    • In vivo studies on the metabolism of estrogens by muscle and adipose tissue of normal males
    • Longcope C, Pratt JH, Schneider SH, Fineberg SE 1976 In vivo studies on the metabolism of estrogens by muscle and adipose tissue of normal males. J Clin Endocrinol Metab 43:1134-1145
    • (1976) J Clin Endocrinol Metab , vol.43 , pp. 1134-1145
    • Longcope, C.1    Pratt, J.H.2    Schneider, S.H.3    Fineberg, S.E.4
  • 4
    • 0019976895 scopus 로고
    • Concentrations of endogenous estradiol as related to estradiol receptor sites in breast tumor cytosol
    • Thorsen T, Tangen M, Stoa KF 1982 Concentrations of endogenous estradiol as related to estradiol receptor sites in breast tumor cytosol. Eur J Cancer Clin Oncol 18:333-337
    • (1982) Eur J Cancer Clin Oncol , vol.18 , pp. 333-337
    • Thorsen, T.1    Tangen, M.2    Stoa, K.F.3
  • 5
    • 0021931084 scopus 로고
    • Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue
    • van Landeghem AAJ, Portman J, Nabauurs M 1985 Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue. Cancer Res 45:2900-2906
    • (1985) Cancer Res , vol.45 , pp. 2900-2906
    • Van Landeghem, A.A.J.1    Portman, J.2    Nabauurs, M.3
  • 6
    • 0016668925 scopus 로고
    • Aromatization of androgen by human abdominal and breast fat tissue
    • Nimrod A, Ryan KJ 1975 Aromatization of androgen by human abdominal and breast fat tissue. J Clin Endocrinol Metab 40:367-372
    • (1975) J Clin Endocrinol Metab , vol.40 , pp. 367-372
    • Nimrod, A.1    Ryan, K.J.2
  • 7
    • 0017283332 scopus 로고
    • Estradiol synthesis from C19 steroids by human breast cancer
    • Miller WR, Forrest APM 1974 Estradiol synthesis from C19 steroids by human breast cancer. Br J Cancer 33:16-18
    • (1974) Br J Cancer , vol.33 , pp. 16-18
    • Miller, W.R.1    Forrest, A.P.M.2
  • 8
    • 0022642042 scopus 로고
    • Aromatase, 17beta; hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal breast tissue in postmenopausal women
    • Vermeulen A, Deslypere JP, Paridaens R, Leclercq C, Roy F, Heuson J C 1986 Aromatase, 17beta; hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal breast tissue in postmenopausal women. Eur J Cancer Clin Oncol 22:515-525
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 515-525
    • Vermeulen, A.1    Deslypere, J.P.2    Paridaens, R.3    Leclercq, C.4    Roy, F.5    Heuson, J.C.6
  • 9
    • 0020326759 scopus 로고
    • A reassessment of the role of breast tumor aromatization
    • Bradlow HL 1982 A reassessment of the role of breast tumor aromatization. Cancer Res 42:3382S-3386S
    • (1982) Cancer Res , vol.42
    • Bradlow, H.L.1
  • 10
    • 0028302746 scopus 로고
    • Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders
    • Sasano H, Nagura H, Harada N, Goukon Y, Kimura M 1994 Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Human Pathol 25:530-535
    • (1994) Human Pathol , vol.25 , pp. 530-535
    • Sasano, H.1    Nagura, H.2    Harada, N.3    Goukon, Y.4    Kimura, M.5
  • 13
    • 0023229552 scopus 로고
    • Correlation of breast tumor aromatase activity and response to aromatase inhibitor with aminoglutethimide
    • Bezwoda WR, Mansoor N, Dansey R 1987 Correlation of breast tumor aromatase activity and response to aromatase inhibitor with aminoglutethimide. Oncology 44:345-349
    • (1987) Oncology , vol.44 , pp. 345-349
    • Bezwoda, W.R.1    Mansoor, N.2    Dansey, R.3
  • 14
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen with the breast
    • Miller WR, O'Neil J 1987 The importance of local synthesis of estrogen with the breast. Steroids 50:537-548
    • (1987) Steroids , vol.50 , pp. 537-548
    • Miller, W.R.1    O'Neil, J.2
  • 15
    • 0029077544 scopus 로고
    • Human testicular aromatase: Immunocytochemical and biochemical studies
    • Inkster SE, Brodie AMH 1995 Human testicular aromatase: immunocytochemical and biochemical studies. J Clin Endocrinol Metab 80:1941-1947
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1941-1947
    • Inkster, S.E.1    Brodie, A.M.H.2
  • 16
    • 0022393956 scopus 로고
    • Preparation and characterization of polyclonal and monoclonal antibodies against human aromatase cytochrome P-450 (P-450arom) and their use in its purification
    • Mendelson CR, Wright EE, Porter JC, Evans CT, Simpson ER 1985 Preparation and characterization of polyclonal and monoclonal antibodies against human aromatase cytochrome P-450 (P-450arom) and their use in its purification. Arch Biochem Biophys 243:480-491
    • (1985) Arch Biochem Biophys , vol.243 , pp. 480-491
    • Mendelson, C.R.1    Wright, E.E.2    Porter, J.C.3    Evans, C.T.4    Simpson, E.R.5
  • 18
    • 0027551416 scopus 로고
    • Proliferating cell nuclear antigen immunostaining in breast cancer and its relation to prognosis
    • Narita T, Funahashi H, Satoh Y, Takagi H 1993 Proliferating cell nuclear antigen immunostaining in breast cancer and its relation to prognosis. Jpn J Clin Oncol 23:20-25
    • (1993) Jpn J Clin Oncol , vol.23 , pp. 20-25
    • Narita, T.1    Funahashi, H.2    Satoh, Y.3    Takagi, H.4
  • 19
    • 0027389069 scopus 로고
    • Proliferating-cell nuclear antigen (PC10) immunolabelling and other proliferation indices as prognostic factors in breast cancer
    • Aaltomaa S, Lipponoe P, Papinaho S, Syrjanen K 1993 Proliferating-cell nuclear antigen (PC10) immunolabelling and other proliferation indices as prognostic factors in breast cancer. J Cancer Res Clin Oncol 119:288-294
    • (1993) J Cancer Res Clin Oncol , vol.119 , pp. 288-294
    • Aaltomaa, S.1    Lipponoe, P.2    Papinaho, S.3    Syrjanen, K.4
  • 20
    • 0027325267 scopus 로고
    • Prediction of early relapse and shortened survival in patients with breast cancer by proliferating cell nuclear antigen score
    • Tahan SR, Neuberg DS, Dieffenbach A, Yacoub L 1993 Prediction of early relapse and shortened survival in patients with breast cancer by proliferating cell nuclear antigen score. Cancer 71:3552-3559
    • (1993) Cancer , vol.71 , pp. 3552-3559
    • Tahan, S.R.1    Neuberg, D.S.2    Dieffenbach, A.3    Yacoub, L.4
  • 22
    • 0006656956 scopus 로고
    • Isolation of a full-length cDNA insert encoding human aromatase system cytochrome p-450 and its expression in nonsteroidogenic cells
    • Corbin C, Graham-Lorence S, McPhaul M, Mason J, Mendelson C, Simpson E 1988 Isolation of a full-length cDNA insert encoding human aromatase system cytochrome p-450 and its expression in nonsteroidogenic cells. Proc Natl Acad Sci USA 85:8948-8952
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8948-8952
    • Corbin, C.1    Graham-Lorence, S.2    McPhaul, M.3    Mason, J.4    Mendelson, C.5    Simpson, E.6
  • 23
    • 0027211128 scopus 로고
    • Detection of aromatase and keratinocyte growth factor expression in breast tumors using reverse transcription-polymerase chain reaction
    • Koos RD, Banks PK, Inkster SE, Yue W, Brodie AMH 1993 Detection of aromatase and keratinocyte growth factor expression in breast tumors using reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol 45:217-212
    • (1993) J Steroid Biochem Mol Biol , vol.45 , pp. 217-1212
    • Koos, R.D.1    Banks, P.K.2    Inkster, S.E.3    Yue, W.4    Brodie, A.M.H.5
  • 24
    • 0017755181 scopus 로고
    • The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen dependent processes in reproduction and breast cancer
    • Brodie AMH, Schwarzel WC, Shaikh AA, Brodie HJ 1977 The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen dependent processes in reproduction and breast cancer. Endocrinology 100:1684-1694
    • (1977) Endocrinology , vol.100 , pp. 1684-1694
    • Brodie, A.M.H.1    Schwarzel, W.C.2    Shaikh, A.A.3    Brodie, H.J.4
  • 25
    • 0024828449 scopus 로고
    • Immunocytochemical studies of aromatase in early and full term human placental tissues: Comparison with biochemical assays
    • Inkster SE, Brodie AMH 1989 Immunocytochemical studies of aromatase in early and full term human placental tissues: comparison with biochemical assays. Biol Reprod 41:889-898
    • (1989) Biol Reprod , vol.41 , pp. 889-898
    • Inkster, S.E.1    Brodie, A.M.H.2
  • 27
    • 0025939110 scopus 로고
    • Expression of aromatase cytochrome P450 in premenopausal and postmenopausal human ovaries: An immunocytochemical study
    • Inkster SE, Brodie AMH 1991 Expression of aromatase cytochrome P450 in premenopausal and postmenopausal human ovaries: an immunocytochemical study. J Clin Endocrinol Metab 73:717-726
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 717-726
    • Inkster, S.E.1    Brodie, A.M.H.2
  • 32
    • 0019422166 scopus 로고
    • Aromatazation of testosterone and oestrogen receptor levels in human breast cancer
    • Li K, Adams JB 1981 Aromatazation of testosterone and oestrogen receptor levels in human breast cancer. J Steroid Biochem Mol Biol 14:269-272
    • (1981) J Steroid Biochem Mol Biol , vol.14 , pp. 269-272
    • Li, K.1    Adams, J.B.2
  • 33
    • 0025805117 scopus 로고
    • Growth regulation of the PCNA gene
    • Baserga R 1991 Growth regulation of the PCNA gene. J Cell Sci 98:433-436
    • (1991) J Cell Sci , vol.98 , pp. 433-436
    • Baserga, R.1
  • 34
    • 0022542049 scopus 로고    scopus 로고
    • Expression of proliferating cell nuclear antigen(PCNA)/Cyclin during the cell cycle
    • Kurki P, Vanderlaan M, Dolbeare F, Gray J, Tan EM Expression of proliferating cell nuclear antigen(PCNA)/Cyclin during the cell cycle. Exp Cell Res 166:209-219
    • Exp Cell Res , vol.166 , pp. 209-219
    • Kurki, P.1    Vanderlaan, M.2    Dolbeare, F.3    Gray, J.4    Tan, E.M.5
  • 35
    • 0023272510 scopus 로고
    • Immunohistochemical detection of proliferating cell nuclear antigen in solid human malignancies
    • Robbins BA, dela Vega D, Ogata K, Tan EM, Nakamura RM 1987 Immunohistochemical detection of proliferating cell nuclear antigen in solid human malignancies. Atch Patho Lab Med 111:841-845
    • (1987) Atch Patho Lab Med , vol.111 , pp. 841-845
    • Robbins, B.A.1    Dela Vega, D.2    Ogata, K.3    Tan, E.M.4    Nakamura, R.M.5
  • 36
    • 0026557138 scopus 로고
    • Interleukin-1 and interleukin-6 in breast cyst fluid: Their role in relegating aromatase activity in breast cancer cells
    • Reed MJ, Coldham NG, Patel S, Ghilchik MW, James VHT 1992 Interleukin-1 and interleukin-6 in breast cyst fluid: their role in relegating aromatase activity in breast cancer cells. J Endocrinol 132:R5-R8
    • (1992) J Endocrinol , vol.132
    • Reed, M.J.1    Coldham, N.G.2    Patel, S.3    Ghilchik, M.W.4    James, V.H.T.5
  • 38
    • 0025785443 scopus 로고
    • Aromatase activity in human adipose tissue stromal cells: The effect of fetal bovine serum fractions on dexamethasone-stimulated aromatization
    • Leuprasitsakul P, Longcope C 1991 Aromatase activity in human adipose tissue stromal cells: the effect of fetal bovine serum fractions on dexamethasone-stimulated aromatization. J Steroid Biochem Mol Biol 39:353-357
    • (1991) J Steroid Biochem Mol Biol , vol.39 , pp. 353-357
    • Leuprasitsakul, P.1    Longcope, C.2
  • 39
    • 0027940222 scopus 로고
    • The role of aromatase in breast tumors
    • Reed MJ 1994 The role of aromatase in breast tumors. Breast Cancer Res Treat 30:7-17
    • (1994) Breast Cancer Res Treat , vol.30 , pp. 7-17
    • Reed, M.J.1
  • 41
    • 0025684712 scopus 로고
    • Relationship between tumor aromatase activity, tumor characteristics and response to therapy
    • Miller WR, Anderson TJ, Jack WLJ 1990 Relationship between tumor aromatase activity, tumor characteristics and response to therapy. J Steroid Biochem Mol Biol 37:1055-111059
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 1055-111059
    • Miller, W.R.1    Anderson, T.J.2    Jack, W.L.J.3
  • 43
    • 0022600388 scopus 로고
    • The neu oncogene encodes an epidermal growth factor receptor-related protein
    • Bargmann CI, Hung MC, Weinberg RA 1986 The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature 319:226-230
    • (1986) Nature , vol.319 , pp. 226-230
    • Bargmann, C.I.1    Hung, M.C.2    Weinberg, R.A.3
  • 45
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with ampliation of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL 1987 Human breast cancer: correlation of relapse and survival with ampliation of the HER-2/neu oncogene. Science 235:177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 47
    • 0026198298 scopus 로고
    • Immunohistochemical assay of neu/c-erbB2 oncogene product in paraffin-embedded tissue in early breast cancer: Retrospective follow-up study of 245 Stage I and P cases
    • Battifora H, Gaffey M, Esteban J, Mehta P, Faucett C 1991 Immunohistochemical assay of neu/c-erbB2 oncogene product in paraffin-embedded tissue in early breast cancer: retrospective follow-up study of 245 Stage I and P cases. Mod Pathol 4:466-474
    • (1991) Mod Pathol , vol.4 , pp. 466-474
    • Battifora, H.1    Gaffey, M.2    Esteban, J.3    Mehta, P.4    Faucett, C.5
  • 48
    • 0026793986 scopus 로고    scopus 로고
    • Overexpression of HER-2/neu, its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer
    • Allred DC, Clark GM, Molona R, Tandon AK, Schnitt SJ, Gilchrist KW Overexpression of HER-2/neu, its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer. Hum Pathol 23:974-979
    • Hum Pathol , vol.23 , pp. 974-979
    • Allred, D.C.1    Clark, G.M.2    Molona, R.3    Tandon, A.K.4    Schnitt, S.J.5    Gilchrist, K.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.