Aromatase expression in a feminizing adrenocortical tumor

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 9, 1996, Pages 3173-3176

  Young, Jacques ^a   Bulun, Serdar E ^b   Agarwal, Veena ^b   Couzinet, Beatrice ^a   Mendelson, Carole R ^b   Simpson, Evan R ^b   Schaison, Gilbert ^a  

^a BICÊTRE HOSPITAL   (France)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; AROMATASE; CORTICOTROPIN; CORTODOXONE; DEOXYCORTICOSTERONE; ESTRADIOL; ESTRONE; FOLLITROPIN; LUTEINIZING HORMONE; PRASTERONE; PRASTERONE SULFATE; TESTOSTERONE;

ADRENAL CORTEX TUMOR; ADULT; CASE REPORT; CONFERENCE PAPER; ENDOCRINE FUNCTION TEST; FEMINIZATION; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROID BLOOD LEVEL;

ADRENAL CORTEX NEOPLASMS; ADRENALECTOMY; ADULT; AROMATASE; BLOTTING, NORTHERN; ESTRADIOL; ESTRONE; GENE EXPRESSION; HUMANS; MALE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0029792963     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.9.3173     Document Type: Conference Paper

References (11)

1. Gabrilove JL, Sharma DC, Wotiz HH, Dorfman RI. 1965 Feminizing adrenal cortical tumors in the male: a review of 52 cases including a case report. Medicine. 44:37-79.
2. Bertagna C, Orth DM. 1981 Clinical and laboratory findings and results of therapy in 58 patients with adrenocortical tumors admitted to a single medical center (1957 to 1978). Am J Med. 71:855-867.
3. Ackerman GE, Smith ME, Mendelson CR, MacDonald PC, Simpson ER. 1981 Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture. J Clin Endocrinol Metab. 53:412-417.
4. Rösier A, Bélanger A, Labrie F. 1992 Mechanisms of androgen production in male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency. J Clin Endocrinol Metab. 75:773-778.
5. Simpson ER, Mahendroo MS, Means GD, et al. 1994 Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev. 15:342-355.
6. Bulun SE, Rosenthal IM, Brodie AMH, et al. 1993 Use of tissue-specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumors, as well as in normal fetal and adult gonads. J Clin Endocrinol Metab. 77:1616-1621.
7. Bulun SE, Mahendroo MS, Simpson ER. 1993 Polymerase chain reaction amplification fails to detect aromatase cytochrome P450 transcripts in normal human endometrium or decidua. J Clin Endocrinol Metab. 76:1458-1463.
8. Santen RI. 1975 Is aromatization of testosterone to estradiol required for inhibition of luteinizing hormone secretion in men? J Clin Invest. 56:1555-1563.
9. Trunet PF, Mueller Ph, Bhatnagar AS, et al. 1993 Open dose-finding study of a new potent and selective nonsteroidal aromatase inhibitor, CGS 20 267, in healthy male subjects. J Clin Endocrinol Metab. 77:319-323.
10. Smith EP, Boyd J, Frank GR, et al. 1994 Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med. 331:1056-1061.
11. Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K. 1995 Aromatase deficiency in a male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab. 80:3689-3697.