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Volumn 82, Issue 1, 1997, Pages 70-74

Alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in adipose tissue of women

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYTOCHROME P450;

EID: 0031036541     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.1.70     Document Type: Article
Times cited : (66)

References (41)
  • 1
    • 0016272566 scopus 로고
    • The involvement of human placental microsomal cytochrome P450 in aromatization
    • Thompson Jr EA, Siiteri PK. 1974 The involvement of human placental microsomal cytochrome P450 in aromatization. J Biol Chem. 249:5373-5378.
    • (1974) J Biol Chem , vol.249 , pp. 5373-5378
    • Thompson Jr., E.A.1    Siiteri, P.K.2
  • 2
    • 0015984830 scopus 로고
    • Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age
    • Hemsell DL, Grodin JM, Brenner PF, Siiteri PK, MacDonald PC. 1974 Plasma precursors of estrogen. II. Correlation of the extent of conversion of plasma androstenedione to estrone with age. J Clin Endocrinol Metab. 38:476-479.
    • (1974) J Clin Endocrinol Metab , vol.38 , pp. 476-479
    • Hemsell, D.L.1    Grodin, J.M.2    Brenner, P.F.3    Siiteri, P.K.4    MacDonald, P.C.5
  • 6
    • 0016668925 scopus 로고
    • Aromatization of androgens by human abdominal and breast fat tissue
    • Nimrod A, Ryan K. 1975 Aromatization of androgens by human abdominal and breast fat tissue. J Clin Endocrinol Metab. 40:367.
    • (1975) J Clin Endocrinol Metab , vol.40 , pp. 367
    • Nimrod, A.1    Ryan, K.2
  • 7
    • 0001820742 scopus 로고
    • The role of extraglandular estrogen in women in health and disease
    • James VHT, Serio M, Giusti G. eds. London: Academic Press
    • Edman CD, MacDonald PC. 1976 The role of extraglandular estrogen in women in health and disease. In: James VHT, Serio M, Giusti G. eds. The endocrine function of the human ovary. London: Academic Press; 135-140.
    • (1976) The Endocrine Function of the Human Ovary , pp. 135-140
    • Edman, C.D.1    MacDonald, P.C.2
  • 8
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen within the breast
    • Miller WR, O'Neill J. 1987 The importance of local synthesis of estrogen within the breast. Steroids. 50:537-548.
    • (1987) Steroids , vol.50 , pp. 537-548
    • Miller, W.R.1    O'Neill, J.2
  • 9
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • Bulun SE, Price TM, Mahendroo MS, Aitken J, Simpson ER. 1993 A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J Clin Endocrinol Metab. 77:1622-1628.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Mahendroo, M.S.3    Aitken, J.4    Simpson, E.R.5
  • 10
    • 0006656956 scopus 로고
    • Isolation of a full length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in non-steroidogenic cells
    • Corbin CJ, Graham-Lorence S, McPhaul M, Mason JI, Mendelson CR, Simpson ER. 1988 Isolation of a full length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in non-steroidogenic cells. Proc Natl Acad Sci USA. 85:8948-8952.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8948-8952
    • Corbin, C.J.1    Graham-Lorence, S.2    McPhaul, M.3    Mason, J.I.4    Mendelson, C.R.5    Simpson, E.R.6
  • 11
    • 0023691843 scopus 로고
    • Cloning of a comparative cDNA encoding human aromatase: Immunochemical identification and sequence analysis
    • Harada N. 1988 Cloning of a comparative cDNA encoding human aromatase: immunochemical identification and sequence analysis. Biochem Biophys Res Commun. 156:725-732.
    • (1988) Biochem Biophys Res Commun , vol.156 , pp. 725-732
    • Harada, N.1
  • 12
    • 0027446505 scopus 로고
    • The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
    • Nelson DR, Kamataki T, Waxman DJ, et al. 1993 The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 12:1-51.
    • (1993) DNA Cell Biol , vol.12 , pp. 1-51
    • Nelson, D.R.1    Kamataki, T.2    Waxman, D.J.3
  • 13
    • 0023242414 scopus 로고
    • Immunohistochemical localization of aromatase cytochrome P-450 and estradiol dehydrogenase in the syncytiotrophoblast of the human placenta
    • Fournet-Dulguerov N, MacLusky NJ, Leranth CZ, et al. 1987 Immunohistochemical localization of aromatase cytochrome P-450 and estradiol dehydrogenase in the syncytiotrophoblast of the human placenta. J Clin Endocrinol Metab. 65:757-764.
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 757-764
    • Fournet-Dulguerov, N.1    MacLusky, N.J.2    Leranth, C.Z.3
  • 14
    • 0017107380 scopus 로고
    • Concentration of oestrogens and androgens in human ovarian venous plasma and follicular fluid throughout the menstrual cycle
    • McNatty KP, Baird DT, Bolton A, Chambers P, Corker CS, MacLean H. 1976 Concentration of oestrogens and androgens in human ovarian venous plasma and follicular fluid throughout the menstrual cycle. J Endocrinol. 71:77-85.
    • (1976) J Endocrinol , vol.71 , pp. 77-85
    • McNatty, K.P.1    Baird, D.T.2    Bolton, A.3    Chambers, P.4    Corker, C.S.5    MacLean, H.6
  • 15
    • 0025320025 scopus 로고
    • Expression of mRNA species encoding steroidogenic enzymes in human follicles and corpora lutea throughout the menstrual cycle
    • Doody K, Lorence MC, Mason JI, Simpson ER. 1990 Expression of mRNA species encoding steroidogenic enzymes in human follicles and corpora lutea throughout the menstrual cycle. J Clin Endocrinol Metab. 70:1041-1045.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1041-1045
    • Doody, K.1    Lorence, M.C.2    Mason, J.I.3    Simpson, E.R.4
  • 16
    • 0021924875 scopus 로고
    • Cellular localization of rat testicular aromatase activity during development
    • Tsai-Morris CH, Aquilana DR, Dufau ML. 1985 Cellular localization of rat testicular aromatase activity during development. Endocrinology. 116:38-46.
    • (1985) Endocrinology , vol.116 , pp. 38-46
    • Tsai-Morris, C.H.1    Aquilana, D.R.2    Dufau, M.L.3
  • 17
    • 0018650264 scopus 로고
    • Acute stimulation of aromatization in Leydig cells by human chorionic gonadotropin in vitro
    • Valladares LE, Payne AH. 1979 Acute stimulation of aromatization in Leydig cells by human chorionic gonadotropin in vitro. Proc Natl Acad Sci USA. 76:4460-4463.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4460-4463
    • Valladares, L.E.1    Payne, A.H.2
  • 18
    • 0021646074 scopus 로고
    • Gonadotropic regulation of aromatase activity in the adult rat testis
    • Tsai-Morris CH, Aquilano DR, Dufau ML. 1984 Gonadotropic regulation of aromatase activity in the adult rat testis. Ann NY Acad Sci. 438:666-669.
    • (1984) Ann NY Acad Sci , vol.438 , pp. 666-669
    • Tsai-Morris, C.H.1    Aquilano, D.R.2    Dufau, M.L.3
  • 19
    • 0016590015 scopus 로고
    • The formation of estrogens by central neuroendocrine tissues
    • Naftolin F, Ryan KJ, Davies IJ, et al. 1975 The formation of estrogens by central neuroendocrine tissues. Recent Prog Horm Res. 31:295-319.
    • (1975) Recent Prog Horm Res , vol.31 , pp. 295-319
    • Naftolin, F.1    Ryan, K.J.2    Davies, I.J.3
  • 20
    • 0022348964 scopus 로고
    • Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system
    • Reselli CE, Horton LE, Resko JA. 1985 Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system. Endocrinology. 117:2471-2474.
    • (1985) Endocrinology , vol.117 , pp. 2471-2474
    • Reselli, C.E.1    Horton, L.E.2    Resko, J.A.3
  • 21
    • 0015362915 scopus 로고
    • Formation of estrogens from androgens by human subcutaneous adipose tissue in vitro
    • Bolt HM, Gobel P. 1972 Formation of estrogens from androgens by human subcutaneous adipose tissue in vitro. Horm Metab Res. 4:312.
    • (1972) Horm Metab Res , vol.4 , pp. 312
    • Bolt, H.M.1    Gobel, P.2
  • 23
    • 8044252957 scopus 로고
    • Endocrine management of malignancies of the prostate, breast, endometrium, kidney and ovary
    • DeGroot LJ, Besser GM, Cahill GF, Marshall JC, Nelson DH, Odell WD, Potts JT Jr., Rubenstein AH, Steinberger E, eds. London: Academic Press
    • Landau RL. 1979 Endocrine management of malignancies of the prostate, breast, endometrium, kidney and ovary. In: DeGroot LJ, Besser GM, Cahill GF, Marshall JC, Nelson DH, Odell WD, Potts JT Jr., Rubenstein AH, Steinberger E, eds. Endocrinology. London: Academic Press; 2111-2124.
    • (1979) Endocrinology , pp. 2111-2124
    • Landau, R.L.1
  • 24
    • 0023177323 scopus 로고
    • Effect of aging and obesity on aromatase activity of human adipose cells
    • Simpson ER, Mendelson CR. 1987 Effect of aging and obesity on aromatase activity of human adipose cells. Am J Clin Nutr. 45:290-295.
    • (1987) Am J Clin Nutr , vol.45 , pp. 290-295
    • Simpson, E.R.1    Mendelson, C.R.2
  • 25
    • 0021930760 scopus 로고
    • Effects of aging and obesity on aromatase activity of human adipose cells
    • Cleland WH, Mendelson CR, Simpson ER. 1985 Effects of aging and obesity on aromatase activity of human adipose cells. J Clin Endocrinol Metab. 60:174-177.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 174-177
    • Cleland, W.H.1    Mendelson, C.R.2    Simpson, E.R.3
  • 26
    • 0028044678 scopus 로고
    • Competitive RT-PCR analysis indicates levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs, and abdomen of women increase with advancing age
    • Bulun SE, Simpson ER. 1994 Competitive RT-PCR analysis indicates levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs, and abdomen of women increase with advancing age. J Clin Endocrinol Metab. 78:428-432.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 428-432
    • Bulun, S.E.1    Simpson, E.R.2
  • 27
    • 0028332035 scopus 로고
    • Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis
    • Simpson ER, Mahendroo MS, Means GD, et al. 1994 Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev. 15:342-355.
    • (1994) Endocr Rev , vol.15 , pp. 342-355
    • Simpson, E.R.1    Mahendroo, M.S.2    Means, G.D.3
  • 28
    • 0027261356 scopus 로고
    • Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue
    • Mahendroo MS, Mendelson CR, Simpson ER. 1993 Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue. J Biol Chem. 268:19463-19470.
    • (1993) J Biol Chem , vol.268 , pp. 19463-19470
    • Mahendroo, M.S.1    Mendelson, C.R.2    Simpson, E.R.3
  • 29
    • 0029820178 scopus 로고    scopus 로고
    • Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients
    • Agarwal VR, Bulun SE, Leitch M, Rohrich R, Simpson ER. 1996 Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients. J Clin Endocrinol Metab. 81:3843-3849.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3843-3849
    • Agarwal, V.R.1    Bulun, S.E.2    Leitch, M.3    Rohrich, R.4    Simpson, E.R.5
  • 30
    • 0029002074 scopus 로고
    • Aromatase P450 gene expression in human adipose tissue: Role of a Jak/STAT pathway in regulation of the adipose-specific promoter
    • Zhao Y, Nichols JE, Bulun SE, Mendelson CR, Simpson ER. 1995 Aromatase P450 gene expression in human adipose tissue: role of a Jak/STAT pathway in regulation of the adipose-specific promoter. J Biol Chem. 270:16449-16457.
    • (1995) J Biol Chem , vol.270 , pp. 16449-16457
    • Zhao, Y.1    Nichols, J.E.2    Bulun, S.E.3    Mendelson, C.R.4    Simpson, E.R.5
  • 31
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. 1979 Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:5294-5299.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 32
    • 0029616317 scopus 로고
    • Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR
    • Agarwal VR, Bulun SE, Simpson ER. 1995 Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR. Mol Cell Probes. 9:453-464.
    • (1995) Mol Cell Probes , vol.9 , pp. 453-464
    • Agarwal, V.R.1    Bulun, S.E.2    Simpson, E.R.3
  • 33
    • 0017809532 scopus 로고
    • Effect of obesity on conversion of plasma androstenedione to estrone in ovulatory and anovulatory young women
    • Edman CD, MacDonald PC. 1978 Effect of obesity on conversion of plasma androstenedione to estrone in ovulatory and anovulatory young women. Am J Obstet Gynecol. 130:456-461.
    • (1978) Am J Obstet Gynecol , vol.130 , pp. 456-461
    • Edman, C.D.1    MacDonald, P.C.2
  • 34
    • 0028787970 scopus 로고
    • Aromatase activity and interleukin-6 production by normal and malignant breast tissues
    • Purohit A, Ghilchik MW, Duncan L, et al. 1995 Aromatase activity and interleukin-6 production by normal and malignant breast tissues. J Clin Endocrinol Metab. 80:3052-3058.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3052-3058
    • Purohit, A.1    Ghilchik, M.W.2    Duncan, L.3
  • 36
    • 0023831082 scopus 로고
    • Aromatase activity in adipose tissue from breast quadrants: A link with tumor site
    • O'Neill JS, Elton RA, Miller WR. 1988 Aromatase activity in adipose tissue from breast quadrants: a link with tumor site. Br Med J. 296:741-743.
    • (1988) Br Med J , vol.296 , pp. 741-743
    • O'Neill, J.S.1    Elton, R.A.2    Miller, W.R.3
  • 38
    • 0029867613 scopus 로고    scopus 로고
    • Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells
    • Crichton MB, Nichols JE, Zhao Y, Bulun SE, Simpson ER. 1996 Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells. Mol Cell Endocrinol. 118:215-220.
    • (1996) Mol Cell Endocrinol , vol.118 , pp. 215-220
    • Crichton, M.B.1    Nichols, J.E.2    Zhao, Y.3    Bulun, S.E.4    Simpson, E.R.5
  • 39
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor a: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargil NS, Spiegleman BM. 1993 Adipose expression of tumor necrosis factor a: direct role in obesity-linked insulin resistance. Science. 259:87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargil, N.S.2    Spiegleman, B.M.3
  • 41
    • 0028533569 scopus 로고
    • The role of interleukin-6 in certain age-related diseases
    • Ershler WB, Sun WH, Binkley N. 1994 The role of interleukin-6 in certain age-related diseases. Drugs Aging. 5:358-365.
    • (1994) Drugs Aging , vol.5 , pp. 358-365
    • Ershler, W.B.1    Sun, W.H.2    Binkley, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.