Multiple splicing events involved in regulation of human aromatase expression by a novel promoter, I.6

Endocrinology

Volumn 139, Issue 4, 1998, Pages 1610-1617

  Shozu, Makio ^b   Zhao, Ying ^b   Bulun, Serdar E ^b   Simpson, Evan R ^a  

^a MONASH MEDICAL CENTRE   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; BUCLADESINE; DEXAMETHASONE; INTERLEUKIN 11; INTERLEUKIN 1BETA;

ARTICLE; BASE MISPAIRING; CARCINOMA CELL; DNA FLANKING REGION; EXON; FETUS; GENE EXPRESSION REGULATION; GRANULOSA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALIGNANT TRANSFORMATION; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; STROMA CELL; TATA BOX; TISSUE SPECIFICITY;

EID: 0031792594     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5878     Document Type: Article

References (38)

1. McNatty KP, Baird DT, Bolton A, Chambers P, Corker CS, MacLean H 1976 Concentration of oestrogens and androgens in human ovarian venous plasma and follicular fluid throughout the menstrual cycle. J Endocrinol 71:77-85
2. Tsai-Morris CH, Aquilana DR, Dufau ML 1985 Cellular localization of rat testicular aromatase activity during development. Endocrinology 116:38-46
3. Naftolin F, Ryan KJ, Davies IJ, Reddy VV, Flores F, Petro Z, Kuhn M, White RJ, Takaoka Y, Wolin L 1975 The formation of estrogens by central neuroendocrine tissues. Recent Prog Horm Res 31:295-319
4. Grodin JM, Siiteri PK, MacDonald PC 1973 Source of estrogen production in postmenopausal women. J Clin Endocrinol Metab 36:207-214
5. Reed MJ, Owen AM, Lai LC, Coldham NG, Ghilchik MW, Sheikh NA, James VHT 1989 In situ oestrone synthesis in normal breast tissue and breast tumor tissue: effect of treatment with 4-hydroxyandrostenedione. Int J Cancer 44:233-237
6. Bulun SE, Economes K, Miller D, Simpson ER 1994 CYP19 (aromatase cytochrome P450) gene expression in human malignant endometrial tumors. J Clin Endocrinol Metab 79:1831-1834
7. Noble LS, Simpson ER, Johns A, Bulun SE 1996 Aromatase expression in endometriosis. J Clin Endocrinol Metab 81:174-179
8. Bulun SE, Simpson ER, Word RA 1994 Expression of the CYP19 gene and its product aromatase cytochrome P450 in human leiomyoma tissues and cells in culture. J Clin Endocrinol Metab 78:736-743
9. Toda K, Akira S, Kishimoto T, Sasaki H, Shizuta Y 1995 Identification of a transcriptional regulatory factor for human aromatase cytochrome P450 gene expression as nuclear factor IL-6 (NF-IL6). Eur J Biochem 231:292-299
10. Sun T, Zhao Y, Fisher CR, Kilgore M, Mendelson CR, Simpson ER, Characterization of cis-acting elements of the human aromatase P450 (CYP19) gene that mediate regulation by retinoids in human choriocarcinoma cells. Proceedings of the 10th International Congress of Endocrinology, San Francisco, California, 1996, p 118
11. Zhao Y, Nichols JE, Bulun SE, Mendelson CR, Simpson ER 1995 Aromatase P450 gene expression in human adipose tissue: role of a Jak/STAT pathway in regulation of the adipose-specific promoter. J Biol Chem 270:16449-16457
12. Zhao Y, Nichols JE, Valdez R, Mendelson CR, Simpson ER 1996 Tumor necrosis factor-α stimulates aromatase gene expression in human adipose stromal cells through use of an activating protein-1 binding site upstream of promoter 1.4. Mol Endocrinol 10:1350-1357
13. Abdelgadir S, Resko J, Ojeda S, Lephart E, McPhaul M, Roselli C 1994 Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain. Endocrinology 135:395-401
14. Abe-Dohmae S, Tanaka R, Takagi Y, Harada N 1996 In vitro increase of aromatase in RNA in diencephalic neurons. Neuroendocrinology 63:46-52
15. Means GD, Kilgore MW, Mahendroo MS, Mendelson CR, Simpson ER 1991 Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues. Mol Endocrinol 5:2005-2013
16. Toda K, Shizuta Y 1993 Molecular cloning of a cDNA showing alternative splicing of the 5′-untranslated sequence of mRNA for human aromatase P450. Eur J Biochem 213:383-389
17. Mahendroo MS, Mendelson CR, Simpson ER 1993 Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue. J Biol Chem 268:19463-19470
18. Harada N, Utsumi T, Takagi Y 1993 Tissue-specific expression of the human aromatase cytochrome P450 gene by alternative use of multiple exons I and promoters, and switching of tissue-specific exons I in carcinogenesis. Proc Natl Acad Sci USA 90:11312-11316
19. Carlone D, Richards J 1997 Functional interactions phosphorylation and levels of 3′,5′-cyclic adenosine monophosphate-regulatory element binding protein and steroidogenic factor-1 mediate hormone-regulated and constitutive expression of aromatase in gonadal cells. Mol Endocrinol 11:292-304
20. Michael MD, Kilgore MW, Morohashi K-I, Simpson ER 1995 Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary. J Biol Chem 270:13561-13466
21. Toda K, Shizuta Y 1994 Identification and characterization of cis-acting regularity elements for the expression of the human aromatase cytochrome P450 gene. J Biol Chem 269:8099-8107
22. Kilgore MW, Means GD, Mendelson CR, Simpson ER 1992 Alternative promotion of aromatase cytochrome P450 expression in human fetal tissues. Mol Cell Endocrinol 83:R9-R16
23. Honda S-I, Harada N, Takagi Y 1994 Novel exon I of the aromatase gene specific for aromatase transcripts in brain. Biochem Biophys Res Commun 198:1153-1160
24. Toda K, Simpson ER, Mendelson CR, Shizuta Y, Kilgore MW 1994 Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues. Mol Endocrinol 8:210-217
25. Shozu M, Zhao Y, Simpson ER 1997 Estrogen biosynthesis in THP-1 cells is regulated by promoter switching of the aromatase (CyP19) gene. Endocrinology 138:5125-5135
26. Toda K, Terashima M, Kamamoto T, Sumimoto H, Yamamoto Y, Sagara Y, Ikeda H, Shizuta Y 1990 Structural and functional characterization of human aromatase P450 gene. Eur J Biochem 193:559-565
27. Ackerman GE, Smith ME, Mendelson CR, MacDonald PC, Simpson ER 1981 Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture. J Clin Endocrinol Metab 53:412-417
28. Bulun SE, Rosenthal IM, Brodie AMH, Inkster SE, Zeller WP, DiGeorge AM, Frasier SD, Kilgore MW, Simpson ER 1993 Use of tissue-specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord rumors, as well as in normal fetal and adult gonads. J Clin Endocrinol Metab 77:1616-1621
29. Shozu M, Simpson E, Expression of aromatase activity in fetal bone. Program of the 79th Annual Meeting of The Endocrine Society, Minneapolis, MN, 1997, p. 238 (Abstract)
30. Kollmar R, Farhanami P 1993 Site-specific initiation of transcription by RNA polymerase II. Proc Soc Exp Biol Med 203:127-139
31. Wobbe C, Strahl K 1990 Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro. Med Cell Biol 10:3859-3867
32. Javehery R, Khachi A, Lo K, Zanzie-Gregory B 1994 DNA sequence requirements for transcriptional initiator activity in mammalian cells. Med Cell Biol 14:116-127
33. Toda K, Terashima M, Mitsuuchi Y, Yamasaki Y, Yokoyama Y, Nojiona S, Ushiro H, Maeda T, Yamamoto Y, Sagara Y, Shizuta Y 1989 Alternative usage of different poly(A) addition signals for two major species of mRNA encoding human aromatase P450. FEBS Lett 247:371-376
34. Corbin CJ, Graham-Lorence S, McPhaul M, Mason JI, Mendelson CR, Simpson ER 1988 Isolation of a full length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in non-steroidogenic cells. Proc Natl Acad Sci USA 85:8948-8952
35. Harada N 1988 Cloning of a comparative cDNA encoding human aromatase: immunochemical identification and sequence analysis. Biochem Biophys Res Commun 156:725-732
36. Means GD, Mahendroo M, Corbin CJ, Mathis JM, Powell FE, Mendelson CR, Simpson ER 1989 Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. J Biol Chem 264:19385-19391
37. Agarwal VR, Bulun SE, Leitch M, Rohrich R, Simpson ER 1996 Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients. J Clin Endocrinol Metab 81:3843-3849
38. Zhou C, Zhou D, Esteban J, Murai J, Siiteri PK, Wilczynski S, Chen S 1996 Aromatase gene expression and its exon I usage in human breast rumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol 59:163-171