-
1
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 260:546-549, 1995
-
(1995)
Science
, vol.260
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
2
-
-
0029073613
-
Weight reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maftei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maftei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
3
-
-
15844409555
-
Role of leptin in fat regulation
-
Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS: Role of leptin in fat regulation (Letter). Nature 380:677, 1996
-
(1996)
Nature
, vol.380
, pp. 677
-
-
Collins, S.1
Kuhn, C.M.2
Petro, A.E.3
Swick, A.G.4
Chrunyk, B.A.5
Surwit, R.S.6
-
4
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of obese gene product
-
Stephens TW, Basinski M, Briatow PK, Bue-Valleskey JM, Burgert SG, Craft L, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A, MacKella W, Rosteck PR Jr, Schoner B, Smith D, Tinsley FC, Zhang XY, Helman M: The role of neuropeptide Y in the antiobesity action of obese gene product. Nature 377:530-532, 1995
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Briatow, P.K.3
Bue-Valleskey, J.M.4
Burgert, S.G.5
Craft, L.6
Hale, J.7
Hoffmann, J.8
Hsiung, H.M.9
Kriauciunas, A.10
MacKella, W.11
Rosteck Jr., P.R.12
Schoner, B.13
Smith, D.14
Tinsley, F.C.15
Zhang, X.Y.16
Helman, M.17
-
5
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
6
-
-
0029939065
-
Decreased food intake does not completely account for adiposity reduction after ob protein infusion
-
Levine N, Nelson C, Gurney A, Vandlen R, De Sauvage F: Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci USA 93:1726-1730, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1726-1730
-
-
Levine, N.1
Nelson, C.2
Gurney, A.3
Vandlen, R.4
De Sauvage, F.5
-
7
-
-
0029983180
-
Obese gene expression: Reduction by fasting and stimulation by insulin and glucose in lean mice and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity
-
Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV: Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proc Natl Acad Sci USA 93:3434-3438, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3434-3438
-
-
Mizuno, T.M.1
Bergen, H.2
Funabashi, T.3
Kleopoulos, S.P.4
Zhong, Y.G.5
Bauman, W.A.6
Mobbs, C.V.7
-
9
-
-
0030039272
-
Abnormal splicing of the leptin receptor gene in db/db mice
-
Lee G-H, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor gene in db/db mice. Nature 379:622-635, 1996
-
(1996)
Nature
, vol.379
, pp. 622-635
-
-
Lee, G.-H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
10
-
-
0029859099
-
Leptin: The tale of an obesity gene
-
Caro JF, Sinha KS, Kolaczynski JW, Zhang PL, Considine RV: Leptin: the tale of an obesity gene. Diabetes 45:1455-1462, 1996
-
(1996)
Diabetes
, vol.45
, pp. 1455-1462
-
-
Caro, J.F.1
Sinha, K.S.2
Kolaczynski, J.W.3
Zhang, P.L.4
Considine, R.V.5
-
11
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M: Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46:313-316, 1997
-
(1997)
Diabetes
, vol.46
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
12
-
-
0029088115
-
Recombinant ob-gene product reduces food intake in fasted mice
-
Rentsch J, Levens W, Chiesi M: Recombinant ob-gene product reduces food intake in fasted mice. Biochem Biophys Res Commun 214:131-136, 1995
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 131-136
-
-
Rentsch, J.1
Levens, W.2
Chiesi, M.3
-
13
-
-
0022408439
-
An improved method for isolation of mouse pancreatic islets
-
Gotoh M, Mayumi H, Himeno K, Tokuda N, Nomoto K: An improved method for isolation of mouse pancreatic islets. Transplantation 40:437-438, 1985
-
(1985)
Transplantation
, vol.40
, pp. 437-438
-
-
Gotoh, M.1
Mayumi, H.2
Himeno, K.3
Tokuda, N.4
Nomoto, K.5
-
14
-
-
0018581535
-
Simple method for collection of pancreatic islets by the use of Ficoll-Conray gradient
-
Okeda T, Ono J, Takaki R, Todo S: Simple method for collection of pancreatic islets by the use of Ficoll-Conray gradient. Endocrinol Jpn 26:495-499, 1979
-
(1979)
Endocrinol Jpn
, vol.26
, pp. 495-499
-
-
Okeda, T.1
Ono, J.2
Takaki, R.3
Todo, S.4
-
15
-
-
0029953957
-
Leptin is a metabolic signal to the reproductive system
-
Barash IA, Cheung CC, Weigle DS, Ren H, Kabigting EB, Kuijper JL, Clifton DK, Steiner RA: Leptin is a metabolic signal to the reproductive system. Endocrinology 137:3144-3147, 1996
-
(1996)
Endocrinology
, vol.137
, pp. 3144-3147
-
-
Barash, I.A.1
Cheung, C.C.2
Weigle, D.S.3
Ren, H.4
Kabigting, E.B.5
Kuijper, J.L.6
Clifton, D.K.7
Steiner, R.A.8
-
16
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G: Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3-10, 1997
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
17
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei MA, Hallas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Med 1:1155-1161, 1995
-
(1995)
Nature Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.A.1
Hallas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
-
18
-
-
0007524724
-
Evidence of free and bound leptin in human circulation
-
Sinha MK, Opentanova I, Ohannesian JP, Kolaczynski JW, Heiman ML, Hale J, Becker GW, Bowsher RR, Stephens TW, Caro JF: Evidence of free and bound leptin in human circulation. J Clin Invest 98:1277-1282, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 1277-1282
-
-
Sinha, M.K.1
Opentanova, I.2
Ohannesian, J.P.3
Kolaczynski, J.W.4
Heiman, M.L.5
Hale, J.6
Becker, G.W.7
Bowsher, R.R.8
Stephens, T.W.9
Caro, J.F.10
-
19
-
-
0030600564
-
Do leptin receptors play a functional role in the endocrine pancreas?
-
Leclercq-Meyer V, Considine RV, Sener A, Malaisse WJ: Do leptin receptors play a functional role in the endocrine pancreas? Biochem Biophys Res Commun 229:794-798, 1996
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 794-798
-
-
Leclercq-Meyer, V.1
Considine, R.V.2
Sener, A.3
Malaisse, W.J.4
-
21
-
-
0021078905
-
Effects of forskolin on insulin release and cyclic AMP content in rat pancreatic islets
-
Wiedenkeller DE, Sharp GWG: Effects of forskolin on insulin release and cyclic AMP content in rat pancreatic islets. Endocrinology 113:2311-2313, 1983
-
(1983)
Endocrinology
, vol.113
, pp. 2311-2313
-
-
Wiedenkeller, D.E.1
Sharp, G.W.G.2
-
22
-
-
2342652901
-
Forskolin: Unique diterpene activator of adenylate cyclase in membranes and intact cells
-
Seamon KB, Padgett W, Daly JW: Forskolin: unique diterpene activator of adenylate cyclase in membranes and intact cells. Proc Natl Acad Sci USA 78:3363-3367, 1981
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 3363-3367
-
-
Seamon, K.B.1
Padgett, W.2
Daly, J.W.3
-
23
-
-
0026053849
-
Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats
-
Bedoya FJ, Jeanrenaud B: Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats. Diabetes 40:15-19, 1991
-
(1991)
Diabetes
, vol.40
, pp. 15-19
-
-
Bedoya, F.J.1
Jeanrenaud, B.2
-
24
-
-
0027367456
-
Stimulus-secretion coupling and insulin secretion in aging: Evaluation of glucose oxidation and ATP-sensitive potassium channel responsiveness
-
Ruhe RC, Curry DL, McDonald RB: Stimulus-secretion coupling and insulin secretion in aging: evaluation of glucose oxidation and ATP-sensitive potassium channel responsiveness. Mechan Aging Develop 71:161-167, 1993
-
(1993)
Mechan Aging Develop
, vol.71
, pp. 161-167
-
-
Ruhe, R.C.1
Curry, D.L.2
Mcdonald, R.B.3
-
25
-
-
2942552582
-
The suppressive effect of enterostatin on various stimuli for insulin secretion in pancreatic islets
-
Ookuma M, York DA, Bray GA: The suppressive effect of enterostatin on various stimuli for insulin secretion in pancreatic islets (Abstract). FASEB J 11:A297, 1997
-
(1997)
FASEB J
, vol.11
-
-
Ookuma, M.1
York, D.A.2
Bray, G.A.3
-
26
-
-
0026742854
-
Effect of a restricted diet on the in vitro glucose-induced insulin release of aging rats
-
Castro M, Pedrosa D, Osuma JI: Effect of a restricted diet on the in vitro glucose-induced insulin release of aging rats. Experimentia 48:996-998, 1992
-
(1992)
Experimentia
, vol.48
, pp. 996-998
-
-
Castro, M.1
Pedrosa, D.2
Osuma, J.I.3
-
27
-
-
0026699305
-
Recovery of glucose-induced insulin secretion in a rat model of NIDDM is not accompanied by return of the β-cell GLUT2 glucose transporter
-
Chen C, Thorens B, Bonner-Weir S, Weir GC, Leahy JL: Recovery of glucose-induced insulin secretion in a rat model of NIDDM is not accompanied by return of the β-cell GLUT2 glucose transporter. Diabetes 41:1320-1327, 1992
-
(1992)
Diabetes
, vol.41
, pp. 1320-1327
-
-
Chen, C.1
Thorens, B.2
Bonner-Weir, S.3
Weir, G.C.4
Leahy, J.L.5
-
28
-
-
0024229140
-
Diet-induced type 2 diabetes in C37BL/6J mice
-
Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN: Diet-induced type 2 diabetes in C37BL/6J mice. Diabetes 37:1163-1167, 1988
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
29
-
-
0029021052
-
Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets
-
Wencel HE, Smother C, Opara EC, Kuhn CM, Feinglos MN, Surwit RS: Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets. Physiol Behav 57:1215-1220, 1995
-
(1995)
Physiol Behav
, vol.57
, pp. 1215-1220
-
-
Wencel, H.E.1
Smother, C.2
Opara, E.C.3
Kuhn, C.M.4
Feinglos, M.N.5
Surwit, R.S.6
-
30
-
-
0026589009
-
Elevated β-cell calmodulin produces a unique insulin secretory defect in transgenic mice
-
Epstein PN, Ribar TJ, Decker GL, Yaney G, Means A: Elevated β-cell calmodulin produces a unique insulin secretory defect in transgenic mice. Endocrinology 130:1387-1393, 1992
-
(1992)
Endocrinology
, vol.130
, pp. 1387-1393
-
-
Epstein, P.N.1
Ribar, T.J.2
Decker, G.L.3
Yaney, G.4
Means, A.5
-
31
-
-
0024456530
-
Comparison of effect of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets
-
Easom RA, Hughes JH, Landt M, Wolf BA, Turk J, McDaniel ML: Comparison of effect of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets. Biochem J 264:27-33, 1989
-
(1989)
Biochem J
, vol.264
, pp. 27-33
-
-
Easom, R.A.1
Hughes, J.H.2
Landt, M.3
Wolf, B.A.4
Turk, J.5
McDaniel, M.L.6
-
33
-
-
0021040104
-
Insulin secretion: Combined effects of phorbol ester and A23187
-
Zawalich W, Brown C, Rasmussen H: Insulin secretion: combined effects of phorbol ester and A23187. Biochem Biophys Res Commun 117:448-455, 1983
-
(1983)
Biochem Biophys Res Commun
, vol.117
, pp. 448-455
-
-
Zawalich, W.1
Brown, C.2
Rasmussen, H.3
-
34
-
-
0022270684
-
2+ and a phorbol ester on insulin secretion from islets of Langerhans permiabilized by high-voltage discharge
-
2+ and a phorbol ester on insulin secretion from islets of Langerhans permiabilized by high-voltage discharge. FEBS Lett 191:102-106, 1985
-
(1985)
FEBS Lett
, vol.191
, pp. 102-106
-
-
Jones, P.M.1
Stutchfield, J.2
Howell, S.L.3
-
35
-
-
0027473729
-
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide 1(7-37)
-
Holz GG IV, Kuhtriber WM, Habener JF: Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide 1(7-37). Nature 361:362-365, 1993
-
(1993)
Nature
, vol.361
, pp. 362-365
-
-
Holz IV, G.G.1
Kuhtriber, W.M.2
Habener, J.F.3
-
36
-
-
0027963204
-
Identification and subcellular characterization of protein kinase C isoforms in insulinoma β-cells and whole islets
-
Knutson KL, Hoenig M: Identification and subcellular characterization of protein kinase C isoforms in insulinoma β-cells and whole islets. Endocrinology 135:881-886, 1994
-
(1994)
Endocrinology
, vol.135
, pp. 881-886
-
-
Knutson, K.L.1
Hoenig, M.2
-
37
-
-
0027993928
-
2+ Channels
-
2+ Channels. J Biol Chem 269:2743-2749, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 2743-2749
-
-
Arkhammar, P.1
Juntti-Berggren, L.2
Larsson, O.3
Welsh, M.4
Nanberg, E.5
Sjoholm, A.6
Kohler, M.7
Berggren, P.-O.8
-
38
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
39
-
-
0026578767
-
Insulin secretion from ob/ob mouse pancreatic islets: Effects of neurotransmitters
-
Tassava TM, Okuda T, Romsos DR: Insulin secretion from ob/ob mouse pancreatic islets: effects of neurotransmitters. Am J Physiol 262:E338-E343, 1992
-
(1992)
Am J Physiol
, vol.262
-
-
Tassava, T.M.1
Okuda, T.2
Romsos, D.R.3
-
40
-
-
0028921575
-
Enhanced sensitivity of pancreatic islets from preobese 2-week-old ob/ob mice to neurohormonal stimulation of insulin secretion
-
Chen N-G, Romsos DR: Enhanced sensitivity of pancreatic islets from preobese 2-week-old ob/ob mice to neurohormonal stimulation of insulin secretion. Endocrinology 136:505-511, 1995
-
(1995)
Endocrinology
, vol.136
, pp. 505-511
-
-
Chen, N.-G.1
Romsos, D.R.2
-
41
-
-
0030601095
-
Signal transduction in isolated islets from the ob/ob mouse: Enhanced sensitivity of protein kinase C stimulation
-
Zawalich WS, Zawalich KC: Signal transduction in isolated islets from the ob/ob mouse: enhanced sensitivity of protein kinase C stimulation. Biochem Biophys Res Commun 223:618-623, 1996
-
(1996)
Biochem Biophys Res Commun
, vol.223
, pp. 618-623
-
-
Zawalich, W.S.1
Zawalich, K.C.2
-
42
-
-
0028791470
-
Effects of short-term culturing on islet phosphoinositide and insulin secretory responses to glucose and carbachol
-
Zawalich WS, Zawalich KC, Kelly GG: Effects of short-term culturing on islet phosphoinositide and insulin secretory responses to glucose and carbachol Acta Diabetologica 32:158-164, 1995
-
(1995)
Acta Diabetologica
, vol.32
, pp. 158-164
-
-
Zawalich, W.S.1
Zawalich, K.C.2
Kelly, G.G.3
|