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Volumn 10, Issue 6, 1999, Pages 1356-1365

T cell costimulatory blockade: New therapies for transplant rejection

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

EID: 0032997619     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (69)

References (72)
  • 1
    • 0026281379 scopus 로고
    • Survival trends in long-term first cadaver-donor kidney transplants
    • edited by Terasaki P, Los Angeles, UCLA Tissue Typing Laboratory
    • Gjertson D: Survival trends in long-term first cadaver-donor kidney transplants. In: Clinical Transplants, edited by Terasaki P, Los Angeles, UCLA Tissue Typing Laboratory, 1991, pp 225-235
    • (1991) Clinical Transplants , pp. 225-235
    • Gjertson, D.1
  • 2
    • 0002634532 scopus 로고    scopus 로고
    • Antigen-independent events leading to chronic graft dysfunction
    • edited by Tilney N, Strom T, Paul L, Philadelphia, Lippincott-Raven
    • Tilney N, Paul L: Antigen-independent events leading to chronic graft dysfunction. In: Transplantation Biology, 1st Ed., edited by Tilney N, Strom T, Paul L, Philadelphia, Lippincott-Raven, 1996, pp 629-637
    • (1996) Transplantation Biology, 1st Ed. , pp. 629-637
    • Tilney, N.1    Paul, L.2
  • 3
    • 0009736430 scopus 로고    scopus 로고
    • Alloantigen-dependent events in chronic rejection
    • edited by Tilney N, Strom T, Paul L, Philadelphia, Lippincott-Raven
    • Paul L, Tilney N: Alloantigen-dependent events in chronic rejection. In: Transplantation Biology, 1st Ed., edited by Tilney N, Strom T, Paul L, Philadelphia, Lippincott-Raven, 1996, pp 567-575
    • (1996) Transplantation Biology, 1st Ed. , pp. 567-575
    • Paul, L.1    Tilney, N.2
  • 4
    • 0028178873 scopus 로고
    • Signals and signs for lymphocyte responses
    • Janeway CA Jr, Bottomly K: Signals and signs for lymphocyte responses. Cell 76: 275-285, 1994
    • (1994) Cell , vol.76 , pp. 275-285
    • Janeway C.A., Jr.1    Bottomly, K.2
  • 5
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • Van Parijs L, Abbas AK: Homeostasis and self-tolerance in the immune system: Turning lymphocytes off. Science (Washington DC) 280: 243-248, 1998
    • (1998) Science (Washington DC) , vol.280 , pp. 243-248
    • Van Parijs, L.1    Abbas, A.K.2
  • 6
    • 0029928584 scopus 로고    scopus 로고
    • Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo
    • Khoruts A, Jenkins MK: Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo. Ann NY Acad Sci 778: 72-79, 1996
    • (1996) Ann NY Acad Sci , vol.778 , pp. 72-79
    • Khoruts, A.1    Jenkins, M.K.2
  • 9
    • 0032543306 scopus 로고    scopus 로고
    • The role of T-cell costimulatory activation pathways in transplant rejection
    • Sayegh MH, Turka LA: The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 338: 1813-1821, 1998
    • (1998) N Engl J Med , vol.338 , pp. 1813-1821
    • Sayegh, M.H.1    Turka, L.A.2
  • 10
    • 0028197430 scopus 로고
    • Mechanisms of T cell recognition of alloantigen: The role of peptides
    • Sayegh MH, Watschinger B, Carpenter CB: Mechanisms of T cell recognition of alloantigen: The role of peptides. Transplantation 57: 1295-1302, 1994
    • (1994) Transplantation , vol.57 , pp. 1295-1302
    • Sayegh, M.H.1    Watschinger, B.2    Carpenter, C.B.3
  • 13
    • 0001913634 scopus 로고
    • The function and mechanism of action of cytolytic lymphocytes
    • edited by Paul WE, New York, Raven
    • Berke G: The function and mechanism of action of cytolytic lymphocytes. In: Fundamental Immunology, 3rd Ed., edited by Paul WE, New York, Raven, 1993, pp 965-974
    • (1993) Fundamental Immunology, 3rd Ed. , pp. 965-974
    • Berke, G.1
  • 15
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP: CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature (Lond) 356: 607-609, 1992
    • (1992) Nature (Lond) , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 16
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins MK, Schwartz RH: Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J Exp Med 165: 302-319, 1987
    • (1987) J Exp Med , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 18
    • 0029851224 scopus 로고    scopus 로고
    • Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases
    • Reiser H, Stadecker MJ: Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases. N Engl J Med 335: 1369-1377, 1996
    • (1996) N Engl J Med , vol.335 , pp. 1369-1377
    • Reiser, H.1    Stadecker, M.J.2
  • 19
    • 0030176384 scopus 로고    scopus 로고
    • Upstream-downstream: CD28 cosignaling pathways and T cell function
    • Rudd CE: Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4: 527-534, 1996
    • (1996) Immunity , vol.4 , pp. 527-534
    • Rudd, C.E.1
  • 21
    • 0027451433 scopus 로고
    • B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance
    • Boussiotis VA, Freeman GJ, Gray G, Gribben J, Nadler LM: B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J Exp Med 178: 1753-1763, 1993
    • (1993) J Exp Med , vol.178 , pp. 1753-1763
    • Boussiotis, V.A.1    Freeman, G.J.2    Gray, G.3    Gribben, J.4    Nadler, L.M.5
  • 22
    • 0027284230 scopus 로고
    • Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
    • Gimmi CD, Freeman GJ, Gribben JG, Gray G, Nadler LM: Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA 90: 6586-6590, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6586-6590
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3    Gray, G.4    Nadler, L.M.5
  • 25
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs L, Ibraghimov A, Abbas AK: The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4: 321-328, 1996
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 26
    • 0032031457 scopus 로고    scopus 로고
    • Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes
    • Van Parijs L, Biuckians A, Abbas AK: Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes. J Immunol 160: 2065-2071, 1998
    • (1998) J Immunol , vol.160 , pp. 2065-2071
    • Van Parijs, L.1    Biuckians, A.2    Abbas, A.K.3
  • 28
    • 0030026869 scopus 로고    scopus 로고
    • IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis: Correlation with induction of Bcl-2
    • Mor F, Cohen IR: IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis: Correlation with induction of Bcl-2. J Immunol 156: 515-522, 1996
    • (1996) J Immunol , vol.156 , pp. 515-522
    • Mor, F.1    Cohen, I.R.2
  • 29
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
    • Refaeli Y, Van Parijs L, London CA, Tschopp J, Abbas AK: Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 8: 615-623, 1998
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    Van Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 31
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel MF, Allison JP: CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med 183: 2533-2540, 1996
    • (1996) J Exp Med , vol.183 , pp. 2533-2540
    • Krummel, M.F.1    Allison, J.P.2
  • 32
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas TL, Bakker CY, Bluestone JA: CTLA-4 ligation blocks CD28-dependent T cell activation. J Exp Med 183: 2541-2550, 1996
    • (1996) J Exp Med , vol.183 , pp. 2541-2550
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 33
    • 0030966217 scopus 로고    scopus 로고
    • Induction of peripheral T cell tolerance in vivo required CTLA-4 engagement
    • Perez V, Parijs LV, Biuckians A, Zheng X, Strom T, Abbas A: Induction of peripheral T cell tolerance in vivo required CTLA-4 engagement. Immunity 6: 411-417, 1997
    • (1997) Immunity , vol.6 , pp. 411-417
    • Perez, V.1    Parijs, L.V.2    Biuckians, A.3    Zheng, X.4    Strom, T.5    Abbas, A.6
  • 36
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH: Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3: 541-547, 1995
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 38
    • 0030902622 scopus 로고    scopus 로고
    • CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion
    • Wu Y, Guo Y, Huang A, Zheng P, Liu Y: CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion. J Exp Med 185: 1327-1335, 1997
    • (1997) J Exp Med , vol.185 , pp. 1327-1335
    • Wu, Y.1    Guo, Y.2    Huang, A.3    Zheng, P.4    Liu, Y.5
  • 39
    • 0029792922 scopus 로고    scopus 로고
    • Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists
    • Madrenas J, Schwartz RH, Germain RN: Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists. Proc Natl Acad Sci USA 93: 9736-9741, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9736-9741
    • Madrenas, J.1    Schwartz, R.H.2    Germain, R.N.3
  • 40
    • 85190643997 scopus 로고    scopus 로고
    • T-cell mediated immunity
    • edited by Janeway CA Jr, Travers P, Singapore, Stamford Press
    • Allison J: T-cell mediated immunity. In: Immunobiology: The Immune System in Health and Disease, 3rd Ed., edited by Janeway CA Jr, Travers P, Singapore, Stamford Press, 1997, pp 7.15-7.31
    • (1997) Immunobiology: The Immune System in Health and Disease, 3rd Ed. , pp. 715-731
    • Allison, J.1
  • 41
    • 0028972549 scopus 로고
    • CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase
    • Truitt KE, Shi J, Gibson S, Segal LG, Mills GB, Imboden JB: CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase. J Immunol 155: 4702-4710, 1995
    • (1995) J Immunol , vol.155 , pp. 4702-4710
    • Truitt, K.E.1    Shi, J.2    Gibson, S.3    Segal, L.G.4    Mills, G.B.5    Imboden, J.B.6
  • 42
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y: JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77: 727-736, 1994
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 43
    • 0028291947 scopus 로고
    • Surface proteins involved in T cell costimulation
    • Mondino A, Jenkins MK: Surface proteins involved in T cell costimulation. J Leukocyte Biol 55: 805-815, 1994
    • (1994) J Leukocyte Biol , vol.55 , pp. 805-815
    • Mondino, A.1    Jenkins, M.K.2
  • 47
    • 0029810388 scopus 로고    scopus 로고
    • Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation
    • Boussiotis VA, Barber DL, Lee BJ, Gribben JG, Freeman GJ, Nadler LM: Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation. J Exp Med 184: 365-376, 1996
    • (1996) J Exp Med , vol.184 , pp. 365-376
    • Boussiotis, V.A.1    Barber, D.L.2    Lee, B.J.3    Gribben, J.G.4    Freeman, G.J.5    Nadler, L.M.6
  • 51
    • 0030587135 scopus 로고    scopus 로고
    • Multiple cis-dominant negative regulation of IL-2 gene expression in anergized T cells
    • Kitagawa-Sakakida S, Schwartz RH: Multiple cis-dominant negative regulation of IL-2 gene expression in anergized T cells. J Immunol 157: 2328-2339, 1996
    • (1996) J Immunol , vol.157 , pp. 2328-2339
    • Kitagawa-Sakakida, S.1    Schwartz, R.H.2
  • 52
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD 154 in cell-mediated immunity
    • Grewal IS, Flavell RA: CD40 and CD 154 in cell-mediated immunity. Annu Rev Immunol 16: 111-135, 1998
    • (1998) Annu Rev Immunol , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 53
    • 0029780119 scopus 로고    scopus 로고
    • CD40 ligand-dependent T cell activation: Requirement of B7-CD28 signaling through CD40
    • Yang Y, Wilson JM: CD40 ligand-dependent T cell activation: Requirement of B7-CD28 signaling through CD40. Science (Washington DC) 273: 1862-1864, 1996
    • (1996) Science (Washington DC) , vol.273 , pp. 1862-1864
    • Yang, Y.1    Wilson, J.M.2
  • 54
    • 0030266492 scopus 로고    scopus 로고
    • CD40L is important for induction of, but not response to, costimulatory activity: ICAM-1 as the second costimulatory molecule rapidly up-regulated by CD40L
    • Shinde S, Wu Y, Guo Y, Niu Q, Xu J, Grewal IS, Flavell R, Liu Y: CD40L is important for induction of, but not response to, costimulatory activity: ICAM-1 as the second costimulatory molecule rapidly up-regulated by CD40L. J Immunol 157: 2764-2768, 1996
    • (1996) J Immunol , vol.157 , pp. 2764-2768
    • Shinde, S.1    Wu, Y.2    Guo, Y.3    Niu, Q.4    Xu, J.5    Grewal, I.S.6    Flavell, R.7    Liu, Y.8
  • 58
    • 0032489862 scopus 로고    scopus 로고
    • CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen
    • Wu Y, Shou Q, Zheng P, Liu Y: CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen. J Exp Med 187: 1151-1156, 1998
    • (1998) J Exp Med , vol.187 , pp. 1151-1156
    • Wu, Y.1    Shou, Q.2    Zheng, P.3    Liu, Y.4
  • 60
    • 0028886953 scopus 로고
    • T cell costimulatory pathways: Promising novel targets for immunosuppression and tolerance induction
    • Sayegh MH, Turka LA: T cell costimulatory pathways: Promising novel targets for immunosuppression and tolerance induction. J Am Soc Nephrol 6: 1143-1150, 1995
    • (1995) J Am Soc Nephrol , vol.6 , pp. 1143-1150
    • Sayegh, M.H.1    Turka, L.A.2
  • 61
    • 0003058879 scopus 로고    scopus 로고
    • Anti-CD 154 therapy to prevent graft rejection
    • Harlan DM, Kirk AD: Anti-CD 154 therapy to prevent graft rejection. Graft 1: 63-70, 1998
    • (1998) Graft , vol.1 , pp. 63-70
    • Harlan, D.M.1    Kirk, A.D.2
  • 62
    • 0031464292 scopus 로고    scopus 로고
    • Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allografts
    • Sayegh M, Zheng X-G, Magee C, Hancock W, Turka L: Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allografts. Transplantation 64: 1646-1650, 1997
    • (1997) Transplantation , vol.64 , pp. 1646-1650
    • Sayegh, M.1    Zheng, X.-G.2    Magee, C.3    Hancock, W.4    Turka, L.5
  • 67
    • 0033557716 scopus 로고    scopus 로고
    • The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival
    • Judge TA, Wu Z, Zheng X-G, Sharpe AH, Sayegh MH, Turka LA: The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival. J Immunol 162: 1947-1951, 1999
    • (1999) J Immunol , vol.162 , pp. 1947-1951
    • Judge, T.A.1    Wu, Z.2    Zheng, X.-G.3    Sharpe, A.H.4    Sayegh, M.H.5    Turka, L.A.6
  • 69
    • 2642655282 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
    • Luhder F, Hoglund P, Allison JP, Benoist C, Mathis D: Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J Exp Med 187: 427-432, 1998
    • (1998) J Exp Med , vol.187 , pp. 427-432
    • Luhder, F.1    Hoglund, P.2    Allison, J.P.3    Benoist, C.4    Mathis, D.5
  • 70
    • 0031047696 scopus 로고    scopus 로고
    • Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively induced model of experimental allergic encephalomyelitis
    • Hurwitz AA, Sullivan TJ, Krummel MF, Sobel RA, Allison JA: Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively induced model of experimental allergic encephalomyelitis. J Neuroimmunol 73: 57-62, 1997
    • (1997) J Neuroimmunol , vol.73 , pp. 57-62
    • Hurwitz, A.A.1    Sullivan, T.J.2    Krummel, M.F.3    Sobel, R.A.4    Allison, J.A.5
  • 72
    • 0030931388 scopus 로고    scopus 로고
    • The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury
    • Takada M, Chandraker A, Nadeau KC, Sayegh MH, Tilney NL: The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury. J Clin Invest 100: 1199-1203, 1997
    • (1997) J Clin Invest , vol.100 , pp. 1199-1203
    • Takada, M.1    Chandraker, A.2    Nadeau, K.C.3    Sayegh, M.H.4    Tilney, N.L.5


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