CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen

Journal of Experimental Medicine

Volumn 187, Issue 7, 1998, Pages 1151-1156

  Wu, Yan ^a   Zhou, Qunmin ^a   Zheng, Pan ^a   Liu, Yang ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; ANTIGEN; B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 2; INTERLEUKIN 4; KEYHOLE LIMPET HEMOCYANIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HELPER CELL; IMMUNIZATION; IMMUNOGLOBULIN PRODUCTION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CLONE CELLS; CYTOKINES; DINITROBENZENES; FLOW CYTOMETRY; HEMOCYANIN; IMMUNIZATION; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; MICE; MICE, KNOCKOUT; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0032489862     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.7.1151     Document Type: Article

References (30)

1. Mueller, D.L., M.K. Jenkins. and R.H. Schwartz. 1989. Clonal expansion vs functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen occupancy. Annu. Rev. Immunol. 7:445-480.
2. Ferguson, S.E., S. Han, G. Kelsoe, and C.B. Thompson. 1996. CD28 is required for germinal center formation. J. Immunol. 156:4576-1581.
3. + T cells and defective antibody production in vivo. J. Exp. Med. 179:809-817.
4. Cause, W.C., S.J. Chen, R.J. Greenwald, M.J. Halvorson, P. Lu, X.D. Xhou, S.C. Morris, K.P. Lee, C.H. June, F.D. Finkelman, et al. 1997. CD28-dependence of T cell differentiation of IL-4 production varies with particular type 2 immune response. J. Immunol. 158:4082-4087.
5. Linsley, P.S., E.A. Clark, and J.A. Ledbetter. 1990. The T cell antigen, CD28, mediates adhesion with B cells by interacting with the activation antigen B7. Proc. Natl. Acad. Sci. USA. 87:5031-5035.
6. Shahinian, A., K. Pfeffer, K. Lee, K.P. Kundig, T.M. Kishihara, A. Wakham, K. Kawai, P.S. Ohashi, C.B. Thompson, and T.W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science. 261:609-612.
7. Zimmermann, C., P. Seiler, P. Lane, and R.M. Zinkernagel. 1997. Anti-viral immune response in CTLA4-transgenic mice. J. Virol. 71:1802-1807.
8. Liu, Y., B. Jones, K. Sullivan, A. Aruffo, P.S. Linsley, and C.A. Janeway, Jr. 1992. The heat-stable antigen is a costimulatory molecule for CD4 T cells. J. Exp. Med. 175:437-445.
9. Liu, Y., B. Jones, W. Brady, C.A. Janeway, Jr., and P.S. Linsley. 1992. Costimulation for CD4 T cell growth: Co-operation of B7 and the heat-stable antigen. Eur. J. Immunol. 22: 2855-2859.
10. Enk, A., and S. Katz. 1994. Heat-stable antigen is an important costimulatory molecule on epidermal Langerhans' cells. J. Immunol. 152:3264-3270.
11. De Bruijn, M.L.H., P.A. Peterson, and M.R. Jackson. 1996. Induction of heat-stable antigen expression by phagocytosis is involved in in vitro activation of unprimed cytotoxic T lymphocytes by macrophages. J. Immunol. 156:2686-2692.
12. Liu, Y., R. Wenger, M. Zhou, and P.J. Nielsen. 1997. Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T cell responses. J. Exp. Med. 185:251-262.
13. Wang, Y.-C., L. Zhu, R. McHugh, K.W. Sell, and P. Selvaraj. 1995. Expression of heat-stable antigen on tumor cells provides co-stimulation for tumor-specific T cell proliferation and cytotoxicity in mice. Eur. J. Immunol. 25:1163-1167.
14. Reiser, H., and B. Benacerraf. 1989. Costimulatory signal provided by a B lymphoid cell line and its Ia-negative variant. Proc. Natl. Acad. Sci. USA. 86:10069-10073.
15. Li, Y., K.E. Hellstrom, S.A. Newby, and L. Chen. 1996. Costimulation and B7-1 induces immunity to poorly immunogenic tumors. J. Exp. Med. 183:639-644.
16. Guo, Y., Y. Wu, S. Shinde, and Y. Liu. 1996. Identification of a CD40 ligand-induced costimulatory molecule as CD44H. J. Exp. Med. 184:955-961.
17. Dubey, C., M. Croft, and S. Swain. 1995. Costimulatory requirement of naive CD4 T cells: ICAM-1 or B7-1 can costimulate naive CD4 T cell activation, but both are required for optimal responses. J. Immunol. 155:45-57.
18. Shinde, S., Y. Wu, Y. Guo, J. Xu, I.S. Grewal, R.A. Flavell, and Y. Liu. 1996. CD40L is important for induction of, but not response to, costimulatory activity: ICAM-1 as the second costimulatory molecule rapidly up-regulated by CD40L. J. Immunol. 157:2764-2768.
19. DeBenedette, M.A., N.R. Chu, K.E. Pollk, J. Hurtodo, W.F. Wade, B.S. Kwon, and T.H. Watts. 1995. Role of 4-1BB ligand in costimulation of T lymphocyte growth and its up-regulation on M12 B lymphoma by cAMP.J. Exp. Med. 181: 985-992.
20. Melero, I., W.W. Shuford, S.A. Newby, A. Aruffo, J.A. Ledbetter, K.E. Hellstrom, R.S. Mittler, and L. Chen. 1997. Monoclonal antibodies against 4-1BB T cell activation molecule eradicate established tumors. Nat. Med. 3:682-685.
21. Nielsen P.J., B. Lorenz, A.M. Müller, R.H. Wenger, F. Brombacher, M. Simon, T. von der Weid, W.J. Langhorne, H. Mossmann, and G. Köhler. 1997. Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood. 89:1058-1067.
22. Wu, Y., Y. Guo, C.A. Janeway, Jr., and Y. Liu. 1995. Signalling by a new anti-Thy-1 monoclonal antibody interfere with B7-2-mediated costimulation for T cell growth. Cell. Immunol. 165:266-277.
23. Foy, T.M., A. Aruffo, J. Bajorath, J. Buhlmann, and R.J. Noelle. 1996. Immune regulation by CD40 and its ligand. Annu. Rev. Immunol. 14:591-618.
24. Mosmann, T.R., and R.L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
25. Finkelman, F.D., J. Holmes, I.M. Katona, J.F. Urban, Jr., M.P. Beckmann, L.S. Park, K.A. Schooley, R.L. Coffman, T.R. Mosmann, and W.E. Paul. 1990. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8:303-333.
26. Ihle, J., B.A. Witthuhn, F.W. Quelle, K. Yamamoto, and O. Silvennoinen. 1995. Signalling through the hematopoietic cytokine receptors. Annu. Rev. Immunol. 13:369-398.
27. Ding, L., J.M. Green, C.B. Thompson, and E.M. Shevach 1995. B7/CD28-dependent and independent induction of CD40 ligand expression. J. Immunol. 155:5124-5132.
28. Kündig, M., A. Shahinian, K. Kawai, H.-W. Mittrücken, E. Sebzda, M.F. Bachmann, T.W. Mak, and P.S. Ohashi. 1996. Duration of TCR stimulation determines costimulatory requirement of T cells. Immunity. 5:41-52.
29. MacLennan, I.C.M. 1994. Germinal centers. Annu. Rev. Immunol. 12:117-139.
30. Kalinke, U., E.M. Bucher, B. Ernst, A. Oxenius, H.P. Roost, S. Geley, R. Kofler, R.M. Zinkernagel, and H. Hengartner. 1996. The role of somatic mutation in the generation of protective humoral immune response against vesicular stomatitis virus. Immunity. 5:639-652.