The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury

Journal of Clinical Investigation

Volumn 100, Issue 5, 1997, Pages 1199-1203

  Takada, Moriatsu ^a   Chandraker, Anil ^a   Nadeau, Kari C ^b   Sayegh, Mohamed H ^a   Tilney, Nicholas L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

CD28 B7; Kidney; Rat; T cell

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CREATININE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNIVERSITY OF WISCONSIN SOLUTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; KIDNEY ISCHEMIA; MALE; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; REPERFUSION INJURY; UNINEPHRECTOMY;

EID: 0030931388     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119632     Document Type: Article

References (32)

1. Land, W., and K. Messmer. 1996. The impact of ischemia/reperfusion injury on specific and nonspecific, early and late chronic events after organ transplantation. Transplant. Rev. 20:108-127.
2. Naimark, D.M.J., and E. Cole. 1994. Determinants of long-term renal allograft survival. Transplant. Rev. 3:93-313.
3. Carpenter, C.B. 1995. Long-term failure of renal transplants: adding insult to injury. Kidney Int. 50:s40-s44.
4. Goes, N., J. Urmson, V. Ramassar, and P.F. Halloran. 1995. Ischemic acute tubular necrosis induces an extensive local cytokine response. Transplantation (Baltimore). 59:565-572.
5. Takada, M., K.C. Nadeau, G.D. Shaw, K.A. Marquette, and N.L. Tilney. 1997. The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the kidney: inhibition by a soluble P-selectin ligand. J. Clin. Invest. 99:1-9.
6. Schwartz, R.H. 1992. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell. 71: 1065-1068.
7. Tan, P., C. Anasetti, J. A. Hansen, J. Melrose, M. Brunvand, J. Bradshaw, J.A. Ledbetter, and P.S. Linsley. 1993. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J. Exp. Med. 177:165-173.
8. Linsley, P.S., A. Clarke, and J.A. Ledbetter. 1990. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc. Natl. Acad. Sci. USA. 87:5031-5035.
9. Linsley, P.S., P.M. Wallace, J. Johnson, M.G. Gibson, J.L. Greene, J.A. Ledbetter, C. Singh, and M.A. Tepper. 1992. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science (Wash. DC). 257:792-795.
10. Lenschow, D.J., Y. Zeng, J.R. Thistlethwaire, A. Montag, W. Brady, M.G. Gibson, P.S. Linsley, and J.A. Bluestone. 1992. Long-term survival of xenogenic pancreatic islet grafts induced by CTLA4Ig. Science (Wash. DC). 257: 789-792.
11. Turka, L.A., P.S. Linsley, H. Lin, W. Brady, J.M. Leiden, R.-Q. Wei, M.L. Gibson, X.-G. Zheng, S. Myrdal, D. Gordon, et al. 1992. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc. Natl. Acad. Sci. USA. 89:11102-11105.
12. Sayegh, M.H., E. Akalin, W.W. Hancock, M.E. Russel, C.B. Carpenter, P.S. Linsley, and L.A. Turka. 1995. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J. Exp. Med. 181:1869-1874.
13. Perico, N., O. Imberti, M. Bontempelli, and G. Remuzzi. 1995. Toward novel antirejection strategies: in vivo immunosuppressive properties of CTLA4Ig. Kidney Int. 47:241-246.
14. Russell, M.E., W.W. Hancock, E. Akalin, A.F. Wallace, T. Glysing-Jensen, T.A. Willett, and M.H. Sayegh. 1996. Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis. J. Clin. Invest. 97:833-838.
15. Azuma, H., A. Chandraker, K.C. Nadeau, W.W. Hancock, C.B. Carpenter, N.L. Tilney, and M.H. Sayegh. 1996. Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection. Proc. Natl. Acad. Sci. USA. 93:12439-12444.
16. Pearson, T.C., D.Z. Alexander, K.J. Winn, P.S. Linsley, R.P. Lowry, and C.P. Larsen. 1994. Transplantation tolerance induced by CTLA4-Ig. Transplantation (Baltimore). 57:1701-1706.
17. Davidson, L., and J.B. Henry. 1969. Clinical Diagnosis by Laboratory Methods. 14th ed. W.B. Saunders Company, Philadelphia, PA. 48 pp.
18. Hancock, W.W., R.H. Lord, A.J. Colby, T. Diamantstein, F.R. Rickles, C. Dijktra, N. Hogg, and N.L. Tilney. 1987. Identification of IL 2R+ T cells and macrophages within rejecting rat cardiac allografts, and comparison of the effects of treatment with anti-IL 2R monoclonal antibody or cyclosporin. J. Immunol. 138:164-170.
19. Platzer, C. S. Ode-Hakim, P. Reike, W.-D. Döcke, R. Ewert, and H.-D. Volk. 1994. Quantitative PCR analysis of cytokine transcription patterns in peripheral mononuclear cells after anti-CD3 rejection therapy using two novel multispecific competitor fragments. Transplantation (Baltimore). 58:264-268.
20. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanitidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-161.
21. Chandraker, A., M.E. Russell, T. Glysing-Jensen, T.A. Willett, and M.H. Sayegh. 1997. T cell costimulatory blockade in experimental chronic cardiac allograft rejection: effects of cyclosporine and donor antigen. Transplantation (Baltimore). 63:1053-1058.
22. Nadeau, K.C., H. Azuma, and N.L. Tilney. 1995. Cytokine expression in chronic rejection: role for MCP-1 and RANTES. Proc. Natl. Acad. Sci. USA. 92:8729-8733.
23. Kelly, K.J., W.W. Williams, Jr., R.B. Colvin, and J.V. Bonventre. 1994. Antibody to intracellular adhesion molecule 1 protects the kidney against ischemic injury. Proc. Natl. Acad. Sci. USA. 91:812-816.
24. Turcovski-Corrales, S.M., R.G. Fenton, G. Peltz, and D.D. Taub. 1995. CD28:B7 interactions promote T cell adhesion. Eur. J. Immunol. 25:3087-3093.
25. Tullius, S.G., and N.L. Tilney. 1995. Both alloantigens-dependent and -independent factors influence chronic allograft rejection. Transplantation (Baltimore). 59:313-318.
26. Sayegh, M.H., and L.A. Turka. 1995. T cell costimulatory pathways: promising novel targets for immunosuppression and tolerance induction. J. Am. Soc. Nephrol. 6:1143-1150.
27. Halloran, P.F., J. Urmson, P.H. Van der Meide, and P. Autenried. 1992. Regulation of MHC expression in vivo. II. IFN-alpha/beta inducers and recombinant IFN-alpha modulate MHC antigen expression in mouse tissues. J. Immunol. 142:4241-4247.
28. Schall, T.J., K. Bacon, K.J. Toy, and D.V. Goeddel. 19911. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature (Lond.). 347:669-671.
29. Russell, M.E., A.F. Wallace, W.W. Hancock, M.H. Sayegh, D.H. Adams, N.E.S. Sibinga, L.R. Wyner, and M.J. Karnovsky. 1995. Upregulation of cytokines associated with macrophage activation in the Lewis-F344 rat transplantation model of chronic cardiac rejection. Transplantation (Baltimore). 59: 572-578.
30. Russell, M.E., A.F. Wallace, L.R. Wyner, J.B. Newell, and M.J. Karnovskv. 1994. Upregulation and modulation of inducible nitric oxide synthase in rat cardiac allografts with chronic rejection and transplant arteriosclerosis. Circulation. 92:457-464.
31. Yamamoto, T., N.A. Noble, D.E. Miller, and W.A. Border. 1994. Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis. Kidney Int. 45:916-927.
32. Sharma, V.K., R.M. Bologa, G.P. Xu, B. Li, J. Mouradian, J. Wang, D. Serur, V. Rao, and M. Suthanthiran. 1996. Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy. Kidney Int. 49: 1297-1303.