메뉴 건너뛰기




Volumn 4, Issue 2, 1999, Pages 129-144

Susceptibility genes for nicotine dependence: A genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study

Author keywords

Genetics; Linkage study; Nicotine dependence; Smoking

Indexed keywords

NICOTINE;

EID: 0032947801     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000518     Document Type: Article
Times cited : (148)

References (77)
  • 3
    • 0003400662 scopus 로고
    • US Department of Health, Education and Welfare: Washington, DC
    • US Department of Health E and Welfare. Smoking and Health; A Report of the Surgeon General. US Department of Health, Education and Welfare: Washington, DC, 1979.
    • (1979) Smoking and Health; A Report of the Surgeon General
  • 4
    • 0013556909 scopus 로고
    • Smoking and other tobacco use: United States, 1987
    • National Center for Health Statistics
    • Schoenborn CA, Boyd G. Smoking and other tobacco use: United States, 1987. National Center for Health Statistics. Vital Health Statistics 1989; 10: 169.
    • (1989) Vital Health Statistics , vol.10 , pp. 169
    • Schoenborn, C.A.1    Boyd, G.2
  • 5
    • 0004005568 scopus 로고
    • US Department of Health and Human Services, Public Health Service, Office on Smoking: Washington, DC
    • US Department of Health and Human Services. The Health Consequences of Smoking: Cancer. A Report of the Surgeon General. US Department of Health and Human Services, Public Health Service, Office on Smoking: Washington, DC, 1982.
    • (1982) The Health Consequences of Smoking: Cancer. A Report of the Surgeon General
  • 7
    • 0002618834 scopus 로고
    • NIDA, the FDA, and nicotine regulation
    • Mathias R, NIDA, the FDA, and nicotine regulation. NIDA Notes 1994; 9: 5-7.
    • (1994) NIDA Notes , vol.9 , pp. 5-7
    • Mathias, R.1
  • 8
    • 0001117914 scopus 로고
    • Cigarette smoking - Attributable mortality and years of potential life lost - United States, 1988-1991
    • Centers for Disease Control and Prevention. Cigarette smoking - attributable mortality and years of potential life lost - United States, 1988-1991. MMWR 1993; 42: 37-39.
    • (1993) MMWR , vol.42 , pp. 37-39
  • 9
    • 0026594727 scopus 로고
    • Addictive drugs: The cigarette experience
    • Schelling TC. Addictive drugs: the cigarette experience. Science 1992; 255: 430-433.
    • (1992) Science , vol.255 , pp. 430-433
    • Schelling, T.C.1
  • 11
    • 0023147518 scopus 로고
    • Prevalence of tobacco dependence and withdrawal
    • Hughes JR, Gust SW, Pechacek TF. Prevalence of tobacco dependence and withdrawal. Am J Psychiatry 1987; 144: 205-208.
    • (1987) Am J Psychiatry , vol.144 , pp. 205-208
    • Hughes, J.R.1    Gust, S.W.2    Pechacek, T.F.3
  • 12
    • 0029935357 scopus 로고    scopus 로고
    • Nicotine addiction and treatment
    • Rose JE. Nicotine addiction and treatment. Annu Rev Med 1996; 47: 493-507.
    • (1996) Annu Rev Med , vol.47 , pp. 493-507
    • Rose, J.E.1
  • 13
    • 0028012523 scopus 로고
    • Genetic and social influences on starting to smoke: A study of Dutch adolescent twins and their parents
    • Boomsma DI, Koopmans JR, Lorenz JP, Doornen V, Orlebeke JF. Genetic and social influences on starting to smoke: a study of Dutch adolescent twins and their parents. Addiction 1994; 89: 219-226.
    • (1994) Addiction , vol.89 , pp. 219-226
    • Boomsma, D.I.1    Koopmans, J.R.2    Lorenz, J.P.3    Doornen, V.4    Orlebeke, J.F.5
  • 14
    • 0002795459 scopus 로고
    • Gonetic influences on smoking behavior
    • Turner JR, Cardon LR, Hewitt JK (eds). Plenum Press: New York
    • Heath AC, Madden PAF. Gonetic influences on smoking behavior. In: Turner JR, Cardon LR, Hewitt JK (eds). Behavior Genetic Approaches in Behavioral Medicine. Plenum Press: New York, 1995, pp 45-66.
    • (1995) Behavior Genetic Approaches in Behavioral Medicine , pp. 45-66
    • Heath, A.C.1    Madden, P.A.F.2
  • 16
    • 4243217082 scopus 로고    scopus 로고
    • Behavior genetic investigation of cigarette smoking and related issues in twins
    • Blum K, Noble EP (eds). CRC Press: New York, 1997, pp
    • Swan GE, Carmelli D. Behavior genetic investigation of cigarette smoking and related issues in twins. In: Blum K, Noble EP (eds). Handbook of Psychiatric Genetics. CRC Press: New York, 1997, pp 387-406.
    • Handbook of Psychiatric Genetics , pp. 387-406
    • Swan, G.E.1    Carmelli, D.2
  • 17
    • 0032990447 scopus 로고    scopus 로고
    • A population-based twin study in women of smoking initiation and nicotine dependence
    • in press
    • Kendler KS, Neale MC, Sullivan PF, Gardner CO, Prescott CA. A population-based twin study in women of smoking initiation and nicotine dependence. Psychol Med 1999; 29: (in press).
    • (1999) Psychol Med , vol.29
    • Kendler, K.S.1    Neale, M.C.2    Sullivan, P.F.3    Gardner, C.O.4    Prescott, C.A.5
  • 21
    • 0024810778 scopus 로고
    • Chronic nicotine exposure and brain nicolinic receptors - Influence of genetic factors
    • Collins AC, Marks MJ. Chronic nicotine exposure and brain nicolinic receptors - influence of genetic factors. Prog Brain Res 1989; 79: 137.
    • (1989) Prog Brain Res , vol.79 , pp. 137
    • Collins, A.C.1    Marks, M.J.2
  • 22
    • 0025779587 scopus 로고
    • Progress towards the development of animal models of smoking-related behaviors
    • Collins AC, Marks MJ. Progress towards the development of animal models of smoking-related behaviors. J Addict Dis 1991; 10: 109-126.
    • (1991) J Addict Dis , vol.10 , pp. 109-126
    • Collins, A.C.1    Marks, M.J.2
  • 23
    • 0025779587 scopus 로고
    • Progress towards the development of animal models of smoking-related behaviors
    • The Haworth Press
    • Collins AC, Marks MJ. Progress towards the development of animal models of smoking-related behaviors. Behavioral and Biochemical Issues in Substance Abuse. The Haworth Press: 1991, pp 109-126.
    • (1991) Behavioral and Biochemical Issues in Substance Abuse , pp. 109-126
    • Collins, A.C.1    Marks, M.J.2
  • 25
    • 0029943635 scopus 로고    scopus 로고
    • Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
    • Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 1996; 382: 255-257.
    • (1996) Nature , vol.382 , pp. 255-257
    • Pontieri, F.E.1    Tanda, G.2    Orzi, F.3    Di Chiara, G.4
  • 26
    • 0031951263 scopus 로고    scopus 로고
    • Functional correlates of nicotine administration: Similarity with drugs of abuse
    • Pontieri FE, Passarelli F, Calò L, Caronti B, Functional correlates of nicotine administration: similarity with drugs of abuse. J Mol Med 1998; 76: 193-201.
    • (1998) J Mol Med , vol.76 , pp. 193-201
    • Pontieri, F.E.1    Passarelli, F.2    Calò, L.3    Caronti, B.4
  • 27
    • 0032104720 scopus 로고    scopus 로고
    • Common aspects of the action of nicotine and other drugs of abuse
    • Picciotto MR. Common aspects of the action of nicotine and other drugs of abuse. Drug Alcohol Depend 1998; 51: 165-172.
    • (1998) Drug Alcohol Depend , vol.51 , pp. 165-172
    • Picciotto, M.R.1
  • 29
    • 0029805769 scopus 로고    scopus 로고
    • Hippocampal synaptic transmission enhanced by low concentrations of nicotine
    • Gray R, Rajan AS, Radcliffe KA, Yakehiro M. Dani JA. Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Nature 1996; 383: 713-716.
    • (1996) Nature , vol.383 , pp. 713-716
    • Gray, R.1    Rajan, A.S.2    Radcliffe, K.A.3    Yakehiro, M.4    Dani, J.A.5
  • 30
    • 0029805271 scopus 로고    scopus 로고
    • Memories of nicotine
    • McCehee DS, Role I.W. Memories of nicotine. Nature 1996; 383: 670-671.
    • (1996) Nature , vol.383 , pp. 670-671
    • McCehee, D.S.1    Role, I.W.2
  • 31
    • 0032495515 scopus 로고    scopus 로고
    • Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine
    • Picciotto MR, Zoli M, Rimondini R, Léna C, Marubio LM, Pich EM et al. Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine. Nature 1998; 391: 173-177.
    • (1998) Nature , vol.391 , pp. 173-177
    • Picciotto, M.R.1    Zoli, M.2    Rimondini, R.3    Léna, C.4    Marubio, L.M.5    Pich, E.M.6
  • 34
    • 0029099107 scopus 로고
    • A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
    • Fernandez-Salguero P, Hoffman SM, Cholerton S, Mohrenweiser H, Raunio H, Rautio A et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet 1995; 57: 653-660.
    • (1995) Am J Hum Genet , vol.57 , pp. 653-660
    • Fernandez-Salguero, P.1    Hoffman, S.M.2    Cholerton, S.3    Mohrenweiser, H.4    Raunio, H.5    Rautio, A.6
  • 35
    • 0031947888 scopus 로고    scopus 로고
    • Genetic polymorphism of drug metabolizing enzymes: New mutations in CYP2D6 and CYP2A6 genes in Japanese
    • Yokoi T, Kamataki T. Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese. Pharm Res 1998; 15: 517-524.
    • (1998) Pharm Res , vol.15 , pp. 517-524
    • Yokoi, T.1    Kamataki, T.2
  • 36
    • 0032565878 scopus 로고    scopus 로고
    • Nicotine metabolism defect reduces smoking
    • Pianezza ML, Sellers EM, Tyndale RF. Nicotine metabolism defect reduces smoking. Nature 1998; 393: 750.
    • (1998) Nature , vol.393 , pp. 750
    • Pianezza, M.L.1    Sellers, E.M.2    Tyndale, R.F.3
  • 38
    • 0031810031 scopus 로고    scopus 로고
    • Depression and self-medication with nicotine: The modifying influence of the dopamine D4 receptor gene
    • Lerman C, Caporaso N, Main D, Audrain J, Boyd NR, Bowman ED et al. Depression and self-medication with nicotine: the modifying influence of the dopamine D4 receptor gene. Health Psychol 1998; 17: 56-62.
    • (1998) Health Psychol , vol.17 , pp. 56-62
    • Lerman, C.1    Caporaso, N.2    Main, D.3    Audrain, J.4    Boyd, N.R.5    Bowman, E.D.6
  • 40
    • 0031867741 scopus 로고    scopus 로고
    • Genetic influences on smoking: Candidate genes
    • Rossing MA. Genetic influences on smoking: candidate genes. Environ Health Perspect 1998; 106: 231-238.
    • (1998) Environ Health Perspect , vol.106 , pp. 231-238
    • Rossing, M.A.1
  • 41
    • 0018240502 scopus 로고
    • Measuring degree of physical dependence to tobacco smoking with roference to individualization of treatment
    • Fagerstrom KO. Measuring degree of physical dependence to tobacco smoking with roference to individualization of treatment. Addict Behav 1978; 3: 235-241.
    • (1978) Addict Behav , vol.3 , pp. 235-241
    • Fagerstrom, K.O.1
  • 42
    • 0024338367 scopus 로고
    • Measuring nicotine dependence: A review of the Fagerstrom Tolerance Questionnaire
    • Fagerstrom KO, Schneider NC. Measuring nicotine dependence: a review of the Fagerstrom Tolerance Questionnaire. [Review], J Behav Med 1989; 12: 159-182.
    • (1989) J Behav Med , vol.12 , pp. 159-182
    • Fagerstrom, K.O.1    Schneider, N.C.2
  • 43
    • 0021260678 scopus 로고
    • Degree of addiction and effectiveness of nicotine gum therapy for smoking
    • Jarvik ME, Schneider NG. Degree of addiction and effectiveness of nicotine gum therapy for smoking. Am J Psychiatry 1984; 141: 790-791.
    • (1984) Am J Psychiatry , vol.141 , pp. 790-791
    • Jarvik, M.E.1    Schneider, N.G.2
  • 44
    • 0021739415 scopus 로고
    • Effect of nicotine chewing gum in smoking cessation
    • Hjalmarson A. Effect of nicotine chewing gum in smoking cessation. JAMA 1984; 252: 2835-2838.
    • (1984) JAMA , vol.252 , pp. 2835-2838
    • Hjalmarson, A.1
  • 45
    • 0013490195 scopus 로고
    • Short-term effects of nicotine gum
    • Grabowski J, Hall SM (eds). Dept of Health and Human Services: Washington, DC
    • Hughes JR, Hatsukami DK. Short-term effects of nicotine gum. In: Grabowski J, Hall SM (eds). Pharmacological Adjuncts in Smoking Cessation. Dept of Health and Human Services: Washington, DC, 1985.
    • (1985) Pharmacological Adjuncts in Smoking Cessation
    • Hughes, J.R.1    Hatsukami, D.K.2
  • 46
  • 47
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic maps: Individual and sex-specific variation in recombination
    • Broman KW, Murray JC, Sheffield VC, White RL, Weber JL. Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am J Hum Genet 1998; 63: 861-869.
    • (1998) Am J Hum Genet , vol.63 , pp. 861-869
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3    White, R.L.4    Weber, J.L.5
  • 48
    • 0029923481 scopus 로고    scopus 로고
    • High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR
    • Hecker KH, Roux KH. High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR. Biotechniques 1996; 20: 478-480.
    • (1996) Biotechniques , vol.20 , pp. 478-480
    • Hecker, K.H.1    Roux, K.H.2
  • 49
    • 0030881661 scopus 로고    scopus 로고
    • Accurate inference of relationships in sib-pair linkage studies
    • Boehnke M, Cox NJ. Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet 1997; 61: 423-429.
    • (1997) Am J Hum Genet , vol.61 , pp. 423-429
    • Boehnke, M.1    Cox, N.J.2
  • 50
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996; 58: 1347-1363.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 51
    • 0030728925 scopus 로고    scopus 로고
    • Allele-sharing models: LOD scores and accurate linkage tests
    • Kong A, Cox NJ. Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 1997; 61: 1179-1188.
    • (1997) Am J Hum Genet , vol.61 , pp. 1179-1188
    • Kong, A.1    Cox, N.J.2
  • 52
    • 0031455789 scopus 로고    scopus 로고
    • Comparison of nonparametric statistics for detection of linkage in nuclear families: Single-marker evaluation
    • Davis S, Weeks DE. Comparison of nonparametric statistics for detection of linkage in nuclear families: single-marker evaluation. Am J Hum Genet 1997; 61: 1431-1444.
    • (1997) Am J Hum Genet , vol.61 , pp. 1431-1444
    • Davis, S.1    Weeks, D.E.2
  • 53
    • 0029598802 scopus 로고
    • Use of exact and adjusted liability scores to detect genes affecting common traits
    • Goldin LR, Chase GA, King TM, Badlner JA, Gershon ES. Use of exact and adjusted liability scores to detect genes affecting common traits. Genet Epidemiol 1995; 12: 765-769.
    • (1995) Genet Epidemiol , vol.12 , pp. 765-769
    • Goldin, L.R.1    Chase, G.A.2    King, T.M.3    Badlner, J.A.4    Gershon, E.S.5
  • 54
    • 0030851777 scopus 로고    scopus 로고
    • True and false positive peaks in genomewide scans: Applications of length-biased sampling to linkage mapping
    • Terwilliger JD, Shannon WD, Lathrop GM, Nolan JP, Goldin LR, Chase GA et al. True and false positive peaks in genomewide scans: applications of length-biased sampling to linkage mapping. Am J Hum Genet 1997; 61: 430-438.
    • (1997) Am J Hum Genet , vol.61 , pp. 430-438
    • Terwilliger, J.D.1    Shannon, W.D.2    Lathrop, G.M.3    Nolan, J.P.4    Goldin, L.R.5    Chase, G.A.6
  • 55
    • 0031456689 scopus 로고    scopus 로고
    • Improvement of the power to detect complex disease genes by regional inference procedures
    • Goldin LR, Chase GA. Improvement of the power to detect complex disease genes by regional inference procedures. Genet Epidemiol 1997; 14: 785-789.
    • (1997) Genet Epidemiol , vol.14 , pp. 785-789
    • Goldin, L.R.1    Chase, G.A.2
  • 56
    • 0028371763 scopus 로고
    • Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci
    • Eaves LJ. Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci. Hered (Edinburgh) 1994; 72: 175-192.
    • (1994) Hered (Edinburgh) , vol.72 , pp. 175-192
    • Eaves, L.J.1
  • 57
    • 0031979443 scopus 로고    scopus 로고
    • Significance levels in complex inheritance
    • Morton NE. Significance levels in complex inheritance. Am J Hum Genet 1998; 62: 690-697.
    • (1998) Am J Hum Genet , vol.62 , pp. 690-697
    • Morton, N.E.1
  • 58
    • 0032231376 scopus 로고    scopus 로고
    • Statistical genetics '98: Bayesian linkage analysis, or: How I learned to stop worrying and love the posterior probability of linkage
    • Vieland VJ. Statistical genetics '98: Bayesian linkage analysis, or: How I learned to stop worrying and love the posterior probability of linkage. Am J Hum Genet 1998; 63: 947-954.
    • (1998) Am J Hum Genet , vol.63 , pp. 947-954
    • Vieland, V.J.1
  • 59
    • 0002985658 scopus 로고    scopus 로고
    • Statistical evidence: A likelihood paradigm (book review)
    • Vieland VJ, Hodge SE. Statistical evidence: a likelihood paradigm (book review). Am J Hum Genet 1998: 63: 283-289.
    • (1998) Am J Hum Genet , vol.63 , pp. 283-289
    • Vieland, V.J.1    Hodge, S.E.2
  • 60
    • 0032231937 scopus 로고    scopus 로고
    • The power to detect linkage in complex disease by means of simple LOD-score analyses
    • Greenberg DA, Abreu P, Hodge SE. The power to detect linkage in complex disease by means of simple LOD-score analyses. Am J Hum Genet 1998; 63: 870-879.
    • (1998) Am J Hum Genet , vol.63 , pp. 870-879
    • Greenberg, D.A.1    Abreu, P.2    Hodge, S.E.3
  • 61
    • 0031066950 scopus 로고    scopus 로고
    • 1996 William Allan award address. Algorithms and inferences: The challenge of multifactorial diseases
    • Elston RC. 1996 William Allan Award Address. Algorithms and inferences: the challenge of multifactorial diseases. Am J Hum Genet 1997; 60: 255-262.
    • (1997) Am J Hum Genet , vol.60 , pp. 255-262
    • Elston, R.C.1
  • 62
    • 0032231299 scopus 로고    scopus 로고
    • Methods of linkage analysis - and the assumptions underlying them
    • Elston RC. Methods of linkage analysis - and the assumptions underlying them. Am J Hum Genet 1998; 63: 931-934.
    • (1998) Am J Hum Genet , vol.63 , pp. 931-934
    • Elston, R.C.1
  • 63
    • 0028949123 scopus 로고
    • Personality and the inheritance of smoking behavior: A genetic perspective
    • Heath AC. Personality and the inheritance of smoking behavior: a genetic perspective. Behav Genet 1995; 25: 103-117.
    • (1995) Behav Genet , vol.25 , pp. 103-117
    • Heath, A.C.1
  • 66
    • 0029561974 scopus 로고
    • Molecular dissection of quantitative traits: Progress and prospects
    • Paterson AH. Molecular dissection of quantitative traits: progress and prospects. PCR Meth Appl 1995; 5: 321-333.
    • (1995) PCR Meth Appl , vol.5 , pp. 321-333
    • Paterson, A.H.1
  • 67
    • 0028952250 scopus 로고
    • High-resolution genetic mapping of complex traits
    • Kruglyak L, Lander ES. High-resolution genetic mapping of complex traits. Am J Hum Genet 1995; 56: 1212-1223.
    • (1995) Am J Hum Genet , vol.56 , pp. 1212-1223
    • Kruglyak, L.1    Lander, E.S.2
  • 68
    • 0029912286 scopus 로고    scopus 로고
    • Limits on fine mapping of complex traits
    • Kruglyak L, Lander ES. Limits on fine mapping of complex traits. Am J Hum Genet 1996; 58: 1092-1093.
    • (1996) Am J Hum Genet , vol.58 , pp. 1092-1093
    • Kruglyak, L.1    Lander, E.S.2
  • 69
    • 0031718093 scopus 로고    scopus 로고
    • Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p, and 22q in a population-based sampled Finnish family set
    • Hovatta I, Lichtermann D, Juvonen H, Suvisaari J, Terwilliger JD, Arajarvi R et al. Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p. 5q, 6p, 8p, 20p, and 22q in a population-based sampled Finnish family set. Mol Psychiatry 1998; 3: 452-457.
    • (1998) Mol Psychiatry , vol.3 , pp. 452-457
    • Hovatta, I.1    Lichtermann, D.2    Juvonen, H.3    Suvisaari, J.4    Terwilliger, J.D.5    Arajarvi, R.6
  • 70
    • 0033358661 scopus 로고    scopus 로고
    • Replication of linkage studies of complex traits: An examination of the variation in position of the peak LOD score
    • submitted
    • Roberts SB, MacLean CJ, Neale MC, Eaves LJ, Kendler KS. Replication of linkage studies of complex traits: an examination of the variation in position of the peak LOD score. Am J Hum Genet (submitted).
    • Am J Hum Genet
    • Roberts, S.B.1    MacLean, C.J.2    Neale, M.C.3    Eaves, L.J.4    Kendler, K.S.5
  • 71
    • 17144452354 scopus 로고    scopus 로고
    • A search for type 1 diabetes susceptibility genes in families from the United Kingdom
    • Mein CA, Esposito L, Dunn MG, Johnson GCL, Timms AE, Goy JV et al. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nature Genet 1998; 19: 297-300.
    • (1998) Nature Genet , vol.19 , pp. 297-300
    • Mein, C.A.1    Esposito, L.2    Dunn, M.G.3    Johnson, G.C.L.4    Timms, A.E.5    Goy, J.V.6
  • 72
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998; 62: 1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 75
    • 0032231766 scopus 로고    scopus 로고
    • Multiple phenotype modeling in gene-mapping studies of quantitative traits: Power advantages
    • Allison DB, Thiel B, St Jean P, Elston RC, Infante MC, Schork NJ. Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages. Am J Hum Genet 1998; 63: 1190-1201.
    • (1998) Am J Hum Genet , vol.63 , pp. 1190-1201
    • Allison, D.B.1    Thiel, B.2    St Jean, P.3    Elston, R.C.4    Infante, M.C.5    Schork, N.J.6
  • 76
    • 0030669122 scopus 로고    scopus 로고
    • Use of siblings as controls in case-control association studies
    • Curtis D. Use of siblings as controls in case-control association studies. Ann Hum Genet 1997; 61: 319-333.
    • (1997) Ann Hum Genet , vol.61 , pp. 319-333
    • Curtis, D.1
  • 77
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ. A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet 1998; 62: 450-458.
    • (1998) Am J Hum Genet , vol.62 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.