Depression and self-medication with nicotine: The modifying influence of the dopamine D4 receptor gene

Health Psychology

Volumn 17, Issue 1, 1998, Pages 56-62

  Lerman, Caryn ^a   Main, David ^a   Audrain, Janet ^a   Caporaso, Neil ^b   Boyd, Neal R ^c   Bowman, Elise D ^b   Shields, Peter G ^b  

^a GEORGETOWN UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c FOX CHASE CANCER CENTER   (United States)

Author keywords

Depression; Genetics; Smoking

Indexed keywords

DOPAMINE 4 RECEPTOR; NICOTINE;

ADULT; ARTICLE; DEPRESSION; FEMALE; GENETIC ANALYSIS; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; SELF MEDICATION; SMOKING;

ADULT; DEPRESSION; FEMALE; GENETIC MARKERS; GENOTYPE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; NICOTINE; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; SELF MEDICATION; SMOKING; SMOKING CESSATION;

EID: 0031810031     PISSN: 02786133     EISSN: None     Source Type: Journal    
DOI: 10.1037/0278-6133.17.1.56     Document Type: Article

References (13)

1. American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington, DC: Author.
2. Anda, R. F., Williamson, D. F., Escobedo, L. G., Mast, E. E., Giovino, G. A., & Remington, P. L. (1990). Depression and the dynamics of smoking: A national perspective. Journal of the American Medical Association, 264, 1541-1545.
3. Asghari, V., Sanyal, S., Buchwaldt, S., Paterson, A., Jovanovic, V., & Van Tol, H. H. (1995). Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. Journal of Neurochemistry, 65, 1157-1165.
4. Benjamin, J., Li, L., Patterson, C., Greenberg, B. D., Murphy, D. L., & Hamer, D. H. (1996). Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nature Genetics, 12, 81-84.
5. Berlin, L, Saïd, S., Spreux-Varoquaux, O., Launay, J. M., Olivares, R., Millet, V., Lecrubier, Y., & Puech, A. J. (1995). A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers. Clinical Pharmacology & Therapeutics, 58, 444-452.
6. Breslau, N., Andreski, P., & Kilbey, M. M. (1991). Nicotine dependence in an urban population of young adults: Prevalence and co-morbidity with depression, anxiety and other substance dependencies. NIDA Research Monograph, 105, 458-459.
7. Breslau, N., Kilbey, M. M., & Andreski, P. (1993). Nicotine dependence and major depression. Archives of General Psychiatry, 50, 31-35.
8. Carmelli, D., Swan, G. E., Robinette, D., & Fabsitz, R. (1992). Genetic influence on smoking - A study of male twins. New England Journal of Medicine, 327, 829-833.
9. Carmody, T. P. (1989). Affect regulation, nicotine addiction, and smoking cessation. Journal of Psychoactive Drugs, 21, 331-342.
10. Corrigall, W. A., Franklin, K. B. J., Coen, K. M., & Clark, P. B. (1992). The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology, 107, 285-289.
11. Hughes, J. R. (1988). Clonidine, depression, and smoking cessation. Journal of the American Medical Association, 259, 2901-2902.
12. Jardine, R., Martin, N. G., & Henderson, A. S. (1984). Genetic covariation between neuroticism and the symptoms of anxiety and depression. Genetic Epidemiology, 1, 89-107.
13. Joffe, R., Lowe, M. R., & Fisher, E. B., Jr. (1981). A validity test of the reasons for smoking scale. Addictive Behaviors, 6, 41-45.